CN104507521B - 吸入器 - Google Patents

吸入器 Download PDF

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Publication number
CN104507521B
CN104507521B CN201380027248.0A CN201380027248A CN104507521B CN 104507521 B CN104507521 B CN 104507521B CN 201380027248 A CN201380027248 A CN 201380027248A CN 104507521 B CN104507521 B CN 104507521B
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CN
China
Prior art keywords
blister
inhaler
axis
drive
rotation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201380027248.0A
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English (en)
Chinese (zh)
Other versions
CN104507521A (zh
Inventor
A.梅利尼奥提斯
A.索利
R.克拉克
L.麦吉尼斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vectura Delivery Devices Ltd
Original Assignee
Vectura Delivery Devices Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vectura Delivery Devices Ltd filed Critical Vectura Delivery Devices Ltd
Publication of CN104507521A publication Critical patent/CN104507521A/zh
Application granted granted Critical
Publication of CN104507521B publication Critical patent/CN104507521B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0053—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal
    • A61M15/0058—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal the used dosages being cut from the carrier
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/003—Particle size control by passing the aerosol trough sieves or filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A61M15/0025—Mouthpieces therefor with caps
    • A61M15/0026—Hinged caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A61M15/0036—Piercing means hollow piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0053—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal
    • A61M15/0056—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal the used dosages being crushed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0053—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal
    • A61M15/006—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal the used dosages being discarded out of the inhaler's housing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0081—Locking means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/19—Constructional features of carpules, syringes or blisters

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
CN201380027248.0A 2012-05-25 2013-05-16 吸入器 Active CN104507521B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1209267.2 2012-05-25
GB1209267.2A GB2502350A (en) 2012-05-25 2012-05-25 Inhaler having means to control the force applied to an actuating lever
PCT/GB2013/051261 WO2013175176A1 (en) 2012-05-25 2013-05-16 Inhaler

Publications (2)

Publication Number Publication Date
CN104507521A CN104507521A (zh) 2015-04-08
CN104507521B true CN104507521B (zh) 2017-04-12

Family

ID=46546684

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380027248.0A Active CN104507521B (zh) 2012-05-25 2013-05-16 吸入器

Country Status (26)

Country Link
US (1) US10183133B2 (https=)
EP (2) EP3388099B1 (https=)
JP (1) JP6255393B2 (https=)
KR (1) KR101849181B1 (https=)
CN (1) CN104507521B (https=)
AR (1) AR091361A1 (https=)
AU (1) AU2013264972B2 (https=)
BR (1) BR112014029111B1 (https=)
CA (1) CA2871173C (https=)
DK (1) DK2846860T3 (https=)
ES (2) ES2836882T3 (https=)
GB (1) GB2502350A (https=)
HU (1) HUE039761T2 (https=)
IL (1) IL235825A (https=)
IN (1) IN2014DN10634A (https=)
MX (1) MX359344B (https=)
NZ (1) NZ700622A (https=)
PL (1) PL2846860T3 (https=)
PT (1) PT2846860T (https=)
RU (1) RU2582755C1 (https=)
SG (1) SG11201406764UA (https=)
SI (1) SI2846860T1 (https=)
TR (1) TR201808143T4 (https=)
TW (1) TWI632925B (https=)
WO (1) WO2013175176A1 (https=)
ZA (1) ZA201408102B (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015006639A1 (en) 2013-07-12 2015-01-15 SILVA, John, H. Mouthpiece for inhalers
EP2878326A1 (en) * 2013-11-27 2015-06-03 Vectura Delivery Devices Limited Inhaler
CN106139335B (zh) * 2015-04-09 2022-12-16 正大天晴药业集团股份有限公司 一种药粉释放装置
JP6619078B2 (ja) * 2015-07-20 2019-12-11 ヴェクトュラ・デリヴァリー・ディヴァイスィズ・リミテッド ドライパウダー吸入器
PE20181307A1 (es) * 2016-01-19 2018-08-10 Novartis Ag Inhalador multidosis
AR108513A1 (es) * 2016-05-25 2018-08-29 Vectura Delivery Devices Ltd Inhalador de polvo seco con dispositivo de ruptura de blíster
CN118750706A (zh) * 2016-12-06 2024-10-11 诺顿（沃特福特）有限公司 具有集成电子模块的吸入装置
GB201812671D0 (en) * 2018-08-03 2018-09-19 Coalesce Product Dev Ltd An inhaler device
EP3622990A1 (en) 2018-09-17 2020-03-18 Vectura Delivery Devices Limited Dry powder inhaler
US12214121B2 (en) * 2018-09-17 2025-02-04 Vectura Delivery Devices Limited Dry powder inhaler
EP3628358A1 (en) 2018-09-25 2020-04-01 Vectura Delivery Devices Limited Inhaler
BR112021023049A8 (pt) * 2019-05-17 2022-10-18 Impel Neuropharma Inc Dispositivo de dispensação nasal de uso único
CA195576S (en) * 2019-11-18 2022-03-08 Vectura Delivery Devices Ltd Inhaler
IL291998B2 (en) 2019-11-18 2025-02-01 Vectura Delivery Devices Ltd Inhaler for use with a compliance monitor
CN114728137B (zh) 2019-11-18 2024-07-12 维克多瑞传送设备有限公司 具有依从性监视器的干粉吸入器
CN114599415B (zh) 2019-11-18 2024-07-23 维克多瑞传送设备有限公司 具有依从性和/或服从性监视器的干粉吸入器
EP4114743B1 (en) 2020-03-06 2024-11-13 Vectura Delivery Devices Limited Process for manufacturing a blister strip for a dry powder inhaler
US20240252770A1 (en) 2021-05-17 2024-08-01 Vectura Delivery Devices Limited Inhaler with an adherence/compliance monitor
JP7629544B2 (ja) * 2021-05-17 2025-02-13 ヴェクトュラ・デリヴァリー・ディヴァイスィズ・リミテッド 乾燥粉末吸入器のためのアドヒアランスモニタ
CA3227842A1 (en) * 2021-08-13 2023-02-16 Norton (Waterford) Limited Dry powder medicament inhaler
EP4137184A1 (en) 2021-08-16 2023-02-22 Vectura Delivery Devices Limited Adherence / compliance monitor for an inhaler
CN115721044A (zh) * 2021-08-30 2023-03-03 深圳市合元科技有限公司 气溶胶生成系统、气溶胶生成装置及控制方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101730559A (zh) * 2007-07-06 2010-06-09 贝林格尔.英格海姆国际有限公司 吸入器
WO2010114506A1 (en) * 2009-03-30 2010-10-07 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Dry powder inhaler device
CN101977646A (zh) * 2008-01-24 2011-02-16 维克多瑞传送设备有限公司 吸入器
CN101980742A (zh) * 2008-01-24 2011-02-23 维克多瑞传送设备有限公司 吸入器

Family Cites Families (4)

* Cited by examiner, † Cited by third party
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GB9004781D0 (en) 1990-03-02 1990-04-25 Glaxo Group Ltd Device
GB2407042B (en) 2003-10-17 2007-10-24 Vectura Ltd Inhaler
WO2010039200A2 (en) * 2008-09-30 2010-04-08 Oriel Therapeutics, Inc. Dry powder inhalers with endless strips and cooperating piercers and related methods
GB201020130D0 (en) * 2010-11-26 2011-01-12 Vectura Delivery Devices Ltd Inhaler

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101730559A (zh) * 2007-07-06 2010-06-09 贝林格尔.英格海姆国际有限公司 吸入器
CN101977646A (zh) * 2008-01-24 2011-02-16 维克多瑞传送设备有限公司 吸入器
CN101980742A (zh) * 2008-01-24 2011-02-23 维克多瑞传送设备有限公司 吸入器
WO2010114506A1 (en) * 2009-03-30 2010-10-07 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Dry powder inhaler device

Also Published As

Publication number Publication date
PT2846860T (pt) 2018-06-20
GB2502350A (en) 2013-11-27
HUE039761T2 (hu) 2019-02-28
TR201808143T4 (tr) 2018-07-23
ES2836882T3 (es) 2021-06-28
DK2846860T3 (en) 2018-08-06
CA2871173C (en) 2018-01-02
KR20150011804A (ko) 2015-02-02
JP2015517370A (ja) 2015-06-22
EP2846860B1 (en) 2018-04-25
MX2014014367A (es) 2015-03-03
SG11201406764UA (en) 2014-11-27
ZA201408102B (en) 2018-05-30
CN104507521A (zh) 2015-04-08
CA2871173A1 (en) 2013-11-28
NZ700622A (en) 2015-12-24
GB2502350A9 (en) 2014-03-19
AR091361A1 (es) 2015-01-28
US10183133B2 (en) 2019-01-22
EP2846860A1 (en) 2015-03-18
IL235825A (en) 2017-06-29
MX359344B (es) 2018-09-26
AU2013264972A1 (en) 2014-10-23
BR112014029111A2 (pt) 2017-06-27
GB201209267D0 (en) 2012-07-04
EP3388099B1 (en) 2020-09-16
HK1203424A1 (en) 2015-10-30
ES2673208T3 (es) 2018-06-20
BR112014029111B1 (pt) 2021-04-27
RU2582755C1 (ru) 2016-04-27
TWI632925B (zh) 2018-08-21
WO2013175176A1 (en) 2013-11-28
JP6255393B2 (ja) 2017-12-27
KR101849181B1 (ko) 2018-05-30
US20150151059A1 (en) 2015-06-04
IN2014DN10634A (https=) 2015-09-11
SI2846860T1 (sl) 2018-09-28
PL2846860T3 (pl) 2018-10-31
AU2013264972B2 (en) 2017-03-09
TW201408340A (zh) 2014-03-01
EP3388099A1 (en) 2018-10-17
IL235825A0 (en) 2015-01-29

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