CN104491635A - Traditional Chinese medicine composition for treating tinea pedis and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating tinea pedis and preparation method thereof Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition for treating tinea pedis. The composition is prepared from the following traditional Chinese medicinal materials in parts by weight: 10-15 parts of rice vinegar, 10-30 parts of garlic, 10-30 parts of pepper, 10-20 parts of radix sophorae flavescentis, 10-15 parts of cortex phellodendri, 10-20 parts of fructus kochiae, 10-20 parts of kaki calyx, 10-15 parts of radix stemonae, 10-15 parts of saposhnicovia divaricata, 10-20 parts of schizonepeta, 10-15 parts of saponin, 10-15 parts of hairyvein agrimony, 10-15 parts of polygonatum kingianum, 10-15 parts of cynanchum paniculatum, 10-15 parts of cortex magnoliae officinalis, 10-15 parts of radix stephaniae tetrandrae, 10-15 parts of sanguisorba officinalis, 10-15 parts of bunge corydalis herb, 10-15 parts of fig, 5-10 parts of frankincense and 5-10 parts of myrrh. The traditional Chinese medicine composition shows remarkable effects of eliminating tinea pedis related pruritus, healing skin and inhibiting fungi, can be used for clinical treatment of primary or secondary tinea manuum, tinea cruris, leuconychia and other fungal infections besides tinea pedis.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of tinea pedis treating Chinese medicine composition and preparation method thereof.
Background technology
Tinea pedis, is commonly called as beriberi, tinea pedis, is the foot dermatosis that pathogenic fungus causes, has infectiousness.Its pathogenic factor is the sebaceous gland owing to not having the fatty acid can secreting Antifungi between vola and toe, and horny layer is nutritious, and foot's sweat gland enriches, and air circulation is poor, is easy to the environment forming damp warm, is beneficial to very much the growth of filamentous fungi.The crowd of gravid woman, diabetics or life-time service hormone, immunosuppressant, due to the decline of skin resistance, is the Susceptible population of tinea pedis.
The main clinic symptoms of tinea pedis comprises: play is itched, localized abscesses, skin injury, sepage, pain, infectivity is to other positions of patient, as infected to the hand formation tinea manuum, infect fingernail (toenail) and form tinea unguium, infect and form tinea cruris to buttocks, groin place, serious meeting causes the secondary infection such as shank erysipelas.
Summary of the invention
The invention provides a kind of tinea pedis treating Chinese medicine composition and preparation method thereof, by extracting, being enriched the content of active component in Chinese medicine composition, providing a kind of Chinese medicine composition for the treatment of tinea pedis safely and effectively.
The Chinese medicine composition that the present invention treats tinea pedis is made up of the crude drug of following weight portion:
Rice vinegar 10-15, Bulbus Allii 10-30, Pericarpium Zanthoxyli 10-30, Radix Sophorae Flavescentis 10-20, Cortex Phellodendri 10-15, Fructus Kochiae 10-20, Calyx Kaki 10-20, Radix Stemonae 10-15, Radix Saposhnikoviae 10-15, Herba Schizonepetae 10-20, Fructus Gleditsia 10-15, Herba Agrimoniae 10-15, Rhizoma Polygonati 10-15, Radix Cynanchi Paniculati 10-15, Cortex Magnoliae Officinalis 10-15, Radix Stephaniae Tetrandrae 10-15, Radix Sanguisorbae 10-15, Herba Violae 10-15, Fructus Fici 10-15, Olibanum 5-10, Myrrha 5-10.
The preferred crude drug by following weight portion of Chinese medicine composition of described treatment tinea pedis is made:
Rice vinegar 10, Bulbus Allii 30, Pericarpium Zanthoxyli 30, Radix Sophorae Flavescentis 20, Cortex Phellodendri 10, the Fructus Kochiae 10, Calyx Kaki 20, the Radix Stemonae 15, Radix Saposhnikoviae 15, Herba Schizonepetae 20, Fructus Gleditsia 10, Herba Agrimoniae 10, Rhizoma Polygonati 10, Radix Cynanchi Paniculati 15, Cortex Magnoliae Officinalis 15, Radix Stephaniae Tetrandrae 5, Radix Sanguisorbae 15, Herba Violae 15, Fructus Fici 15, Olibanum 5, Myrrha 5.
On the other hand, the invention provides a kind of Chinese medicine composition preparation method for the treatment of tinea pedis, comprise following step
Rapid:
(1) get the raw materials ready, take the crude drug of the above proportioning;
(2) garlic peeling, grinds to form mashed garlic, adds the pure water of a times amount, regulates pH to 6-6.5, adds allinase enzymolysis 0.5-1h at 30-38 DEG C, obtain enzymolysis solution for subsequent use;
(3) Olibanum, Myrrha, Pericarpium Zanthoxyli crushed after being dried are to 30-50 order, and add the enzymolysis solution of step (2) gained, after steam distillation, oil-water separation obtains quintessence oil;
(4) Radix Sophorae Flavescentis, Cortex Phellodendri, the Fructus Kochiae, Calyx Kaki, the Radix Stemonae, Radix Saposhnikoviae, Herba Schizonepetae, Fructus Gleditsia, Herba Agrimoniae, Rhizoma Polygonati, Radix Cynanchi Paniculati, Cortex Magnoliae Officinalis, Radix Stephaniae Tetrandrae, Radix Sanguisorbae, Herba Violae, Fructus Fici add 5-10 and doubly measure pure water, decoct 2-3h, filter, obtain filtrate 1 for subsequent use, medicinal residues add the soak by water 1-2h of 3-5 times amount, and filter, medicinal residues discard, obtain filtrate 2 to merge with filtrate 1, be evaporated to the concentrated solution that relative density is 1.2-1.3;
(5) namely rice vinegar, quintessence oil obtain the Chinese medicine composition for the treatment of tinea pedis of the present invention after adding concentrated solution.
Beneficial effect of the present invention: the Chinese medicine composition for the treatment of tinea pedis provided by the invention obviously can alleviate the symptom such as pruritus, erosion, pain of tinea pedis, and show obvious fungus inhibit activities, except tinea pedis, also can be used for constitutional or the secondary fungal infections such as the tinea manuum, tinea cruris, tinea unguium.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described further.
The Chinese medicine composition of embodiment 1 tinea pedis
Take the crude drug rice vinegar 10 of following weight portion, Bulbus Allii 30, Pericarpium Zanthoxyli 30, Radix Sophorae Flavescentis 20, Cortex Phellodendri 10, the Fructus Kochiae 10, Calyx Kaki 20, the Radix Stemonae 15, Radix Saposhnikoviae 15, Herba Schizonepetae 20, Fructus Gleditsia 10, Herba Agrimoniae 10, Rhizoma Polygonati 10, Radix Cynanchi Paniculati 15, Cortex Magnoliae Officinalis 15, Radix Stephaniae Tetrandrae 5, Radix Sanguisorbae 15, Herba Violae 15, Fructus Fici 15, Olibanum 5, Myrrha 5.
Garlic peeling, grinds to form mashed garlic, adds the pure water of a times amount, regulates pH to 6.5, adds allinase enzymolysis 0.5 at 35 DEG C, obtain enzymolysis solution for subsequent use; Olibanum, Myrrha, Pericarpium Zanthoxyli crushed after being dried to 40 order, add enzymolysis solution, after steam distillation, oil-water separation obtains quintessence oil; Radix Sophorae Flavescentis, Cortex Phellodendri, the Fructus Kochiae, Calyx Kaki, the Radix Stemonae, Radix Saposhnikoviae, Herba Schizonepetae, Fructus Gleditsia, Herba Agrimoniae, Rhizoma Polygonati, Radix Cynanchi Paniculati, Cortex Magnoliae Officinalis, Radix Stephaniae Tetrandrae, Radix Sanguisorbae, Herba Violae, Fructus Fici add 8 times and measure pure water, decoct 3h, filter, obtain filtrate 1 for subsequent use, medicinal residues add the soak by water 2h of 5 times amount, and filter, medicinal residues discard, obtain filtrate 2 to merge with filtrate 1, be evaporated to the concentrated solution that relative density is 1.2; Namely rice vinegar, quintessence oil obtain the Chinese medicine composition for the treatment of tinea pedis after adding concentrated solution, sooner or later smear twice.
The Chinese medicine composition of embodiment 2 tinea pedis
Take the crude drug rice vinegar 15 of following weight portion, Bulbus Allii 30, Pericarpium Zanthoxyli 30, Radix Sophorae Flavescentis 0, Cortex Phellodendri 15, the Fructus Kochiae 10, Calyx Kaki 10, the Radix Stemonae 10, Radix Saposhnikoviae 10, Herba Schizonepetae 10, Fructus Gleditsia 10, Herba Agrimoniae 15, Rhizoma Polygonati 15, Radix Cynanchi Paniculati 15, Cortex Magnoliae Officinalis 15, Radix Stephaniae Tetrandrae 15, Radix Sanguisorbae 15, Herba Violae 15, Fructus Fici 15, Olibanum 10, Myrrha 10.
Garlic peeling, grinds to form mashed garlic, adds the pure water of a times amount, regulates pH to 6.5, adds allinase enzymolysis 0.5 at 35 DEG C, obtain enzymolysis solution for subsequent use; Olibanum, Myrrha, Pericarpium Zanthoxyli crushed after being dried to 40 order, add enzymolysis solution, after steam distillation, oil-water separation obtains quintessence oil; Radix Sophorae Flavescentis, Cortex Phellodendri, the Fructus Kochiae, Calyx Kaki, the Radix Stemonae, Radix Saposhnikoviae, Herba Schizonepetae, Fructus Gleditsia, Herba Agrimoniae, Rhizoma Polygonati, Radix Cynanchi Paniculati, Cortex Magnoliae Officinalis, Radix Stephaniae Tetrandrae, Radix Sanguisorbae, Herba Violae, Fructus Fici add 8 times and measure pure water, decoct 3h, filter, obtain filtrate 1 for subsequent use, medicinal residues add the soak by water 2h of 5 times amount, and filter, medicinal residues discard, obtain filtrate 2 to merge with filtrate 1, be evaporated to the concentrated solution that relative density is 1.2; Namely rice vinegar, quintessence oil obtain the Chinese medicine composition for the treatment of tinea pedis after adding concentrated solution, sooner or later smear twice.
Embodiment 3 tinea pedis treating effect assessment
Case load: 60 example, the range of age 30-60 year, man 40 example, female 20 example;
Symptom: interphalangeal erosion, blister, stench, pruritus;
Grouping: 60 routine tinea pedis patients are divided into 4 groups: matched group, embodiment 1 group, embodiment 2 groups, clotrimazole group.
Criterion of therapeutical effect: cure: foot is rotten to the corn dry, without gargalesthesia, without blister, desquamation;
Effective: blister reduces, gargalesthesia alleviates, and has slight desquamation;
Invalid: without positive effect, blister increases, local gargalesthesia, desquamation.
Medication is statistics each group of therapeutic effect after two weeks, specifically see table 1.
Table 1, tinea pedis treating effect
Table 1 result of the test shows the present invention's traditional Chinese medicine composition for treating tinea pedis and has the cure rate doubling conventional clotrimazole, improvement successful for tinea pedis is more excellent, determined curative effect, cost is low, and have no side effect, can be used for the treatment of the fungal infection class disease such as tinea pedis, the tinea manuum, tinea cruris and tinea unguium clinically.
Embodiment 4 model case
Patient high certain, man, 23 years old, erosive type tinea pedis, blister, desquamation, had obvious gargalesthesia, and after using clotrimazole, daktarin, tinea pedis is repeatedly repeatedly, and blister after two weeks is dry, gargalesthesia disappears to use the Chinese medicine composition of the embodiment of the present invention 1 to smear, and damaged skin starts to heal.
Patient Lee, man, 32 years old, exists rotten to the corn, sepage between biped 6 toes, have strong gargalesthesia, desquamation is obvious, and stench, has obvious pain during walking, and after using the Chinese medicine composition of the embodiment of the present invention 1 to smear surrounding, gargalesthesia disappears, without sepage, breakage skin dries up, and stink alleviates, pain with no pressure.
Patient Zeng, female, 35 years old, the concurrent tinea manuum of tinea pedis, the sepage of biped interphalangeal erosion, have lasting strong gargalesthesia, stench, right ring finger both sides exist dark in property blister in groups, and gargalesthesia is obvious, the embodiment of the present invention 2 Chinese medicine composition is used to smear the hand blister minimizing after two weeks of hands, sufficient affected part, gargalesthesia disappears, and biped sepage disappears, and damaged skin heals gradually, gargalesthesia alleviates, and only interval occurs.
Grandson patient, man, 25 years old, groin place, right side large area keratinization, and increase gradually, have obvious gargalesthesia, after using the embodiment of the present invention 2 Chinese medicine composition to smear surrounding, thicken skin and recover, gargalesthesia disappears, negative fungal examination.
Patient Lee, female 34 years old, the sepage of biped interphalangeal erosion, strong pruritus, tinea pedis secondary biped tinea unguium 5, after using the Chinese medicine composition of the embodiment of the present invention 2 to smear surrounding, tinea pedis erosion disappears, pruritus alleviates, and after continuing to smear 4 months, 4 tinea unguium grow new toenail by root.
Chinese medicine composition of the present invention all shows desirable elimination pruritus, healing skin and fungus inhibitory action in the fungal infection treatments such as the tinea manuum, tinea pedis, tinea cruris, tinea unguium, can be used for the clinical treatment of above fungal infection.
Claims (6)
1. treat a Chinese medicine composition for tinea pedis, it is characterized in that being made up of the crude drug of following weight portion:
Rice vinegar 10-15, Bulbus Allii 10-30, Pericarpium Zanthoxyli 10-30, Radix Sophorae Flavescentis 10-20, Cortex Phellodendri 10-15, Fructus Kochiae 10-20, Calyx Kaki 10-20, Radix Stemonae 10-15, Radix Saposhnikoviae 10-15, Herba Schizonepetae 10-20, Fructus Gleditsia 10-15, Herba Agrimoniae 10-15, Rhizoma Polygonati 10-15, Radix Cynanchi Paniculati 10-15, Cortex Magnoliae Officinalis 10-15, Radix Stephaniae Tetrandrae 10-15, Radix Sanguisorbae 10-15, Herba Violae 10-15, Fructus Fici 10-15, Olibanum 5-10, Myrrha 5-10.
2. the Chinese medicine composition for the treatment of tinea pedis as claimed in claim 1, is characterized in that: be made up of the crude drug of following weight portion:
Rice vinegar 10, Bulbus Allii 30, Pericarpium Zanthoxyli 30, Radix Sophorae Flavescentis 20, Cortex Phellodendri 10, the Fructus Kochiae 10, Calyx Kaki 20, the Radix Stemonae 15, Radix Saposhnikoviae 15, Herba Schizonepetae 20, Fructus Gleditsia 10, Herba Agrimoniae 10, Rhizoma Polygonati 10, Radix Cynanchi Paniculati 15, Cortex Magnoliae Officinalis 15, Radix Stephaniae Tetrandrae 5, Radix Sanguisorbae 15, Herba Violae 15, Fructus Fici 15, Olibanum 5, Myrrha 5.
3. the Chinese medicine composition for the treatment of tinea pedis as claimed in claim 1, is characterized in that being made up of the crude drug of following weight portion:
Rice vinegar 15, Bulbus Allii 30, Pericarpium Zanthoxyli 30, Radix Sophorae Flavescentis 0, Cortex Phellodendri 15, the Fructus Kochiae 10, Calyx Kaki 10, the Radix Stemonae 10, Radix Saposhnikoviae 10, Herba Schizonepetae 10, Fructus Gleditsia 10, Herba Agrimoniae 15, Rhizoma Polygonati 15, Radix Cynanchi Paniculati 15, Cortex Magnoliae Officinalis 15, Radix Stephaniae Tetrandrae 15, Radix Sanguisorbae 15, Herba Violae 15, Fructus Fici 15, Olibanum 10, Myrrha 10.
4. the preparation method of the Chinese medicine composition of the treatment tinea pedis described in any one of claim 1-3, is characterized in that comprising the steps:
(1) get the raw materials ready, take the crude drug of the above proportioning;
(2) garlic peeling, grinds to form mashed garlic, adds the pure water of a times amount, regulates pH to 6-6.5, adds allinase enzymolysis 0.5-1h at 30-38 DEG C, obtain enzymolysis solution for subsequent use;
(3) Olibanum, Myrrha, Pericarpium Zanthoxyli crushed after being dried are to 30-50 order, and add the enzymolysis solution of step (2) gained, after steam distillation, oil-water separation obtains quintessence oil;
(4) Radix Sophorae Flavescentis, Cortex Phellodendri, the Fructus Kochiae, Calyx Kaki, the Radix Stemonae, Radix Saposhnikoviae, Herba Schizonepetae, Fructus Gleditsia, Herba Agrimoniae, Rhizoma Polygonati, Radix Cynanchi Paniculati, Cortex Magnoliae Officinalis, Radix Stephaniae Tetrandrae, Radix Sanguisorbae, Herba Violae, Fructus Fici add 5-10 and doubly measure pure water, decoct 2-3h, filter, obtain filtrate 1 for subsequent use, medicinal residues add the soak by water 1-2h of 3-5 times amount, and filter, medicinal residues discard, obtain filtrate 2 to merge with filtrate 1, be evaporated to the concentrated solution that relative density is 1.2-1.3;
(5) namely rice vinegar, quintessence oil obtain the Chinese medicine composition for the treatment of tinea pedis after adding concentrated solution.
5. the preparation method of the Chinese medicine composition for the treatment of tinea pedis as claimed in claim 4, is characterized in that: pH value is 6.5.
6. the preparation method of the Chinese medicine composition of Hepatoma therapy as claimed in claim 4, is characterized in that Olibanum, Myrrha, Pericarpium Zanthoxyli crushed after being dried to 40 order.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105214066A (en) * | 2015-11-19 | 2016-01-06 | 赵岱 | A kind of foot bath gelatin being used for the treatment of beriberi |
| CN106215066A (en) * | 2016-09-27 | 2016-12-14 | 杨巧霞 | Treat the Traditional Chinese medicine foot soaping liquid of chronic tinea pedis acute attack stage |
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2014
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105214066A (en) * | 2015-11-19 | 2016-01-06 | 赵岱 | A kind of foot bath gelatin being used for the treatment of beriberi |
| CN106215066A (en) * | 2016-09-27 | 2016-12-14 | 杨巧霞 | Treat the Traditional Chinese medicine foot soaping liquid of chronic tinea pedis acute attack stage |
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