CN104491516A - 治疗肾结石的中药 - Google Patents

治疗肾结石的中药 Download PDF

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CN104491516A
CN104491516A CN201410735619.7A CN201410735619A CN104491516A CN 104491516 A CN104491516 A CN 104491516A CN 201410735619 A CN201410735619 A CN 201410735619A CN 104491516 A CN104491516 A CN 104491516A
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王志军
丛英珍
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Abstract

本发明涉及一种药物配方领域，具体地说是一种治疗肾结石的中药，其特征在于，以重量百分比计由如下原料药制成：通淋草7～10％；猫须草4～6％；鸡肫草8～11％；陆英叶7～10％；萆薢9～12％；关木通6～9％；补骨脂2～5％；夏天无3～5％；木槿花2～5％；千日红4～7％；五味藤2～6％；忍冬藤2～5％；佛手3～6％；委陵菜2～4％；鸡矢藤2～4％；芦根2～5％；猪笼草3～5％；岗稔根3～5％；川朴4～6％，将上述原料药加水煎熬后去渣得滤液。本发明具有消炎止痛、活血化瘀、行气散结、利尿排石之功效，适用于有腰部酸痛、周身乏力、排尿不畅、血尿等症状的肾结石患者。

Description

治疗肾结石的中药
技术领域
本发明涉及一种中成药制剂，具体地说是一种用于治疗肾结石的中药。
背景技术
众所周知，肾结石是一种多发病、常见病，临床以肾绞痛和血尿为主要症状，常会引起尿路梗阻，和继发性感染，根据结石成分的不同，肾结石可分草酸钙结石、磷酸钙结石、尿酸结石、磷酸铵镁结石、胱氨酸结石及嘌呤结石六类，临床常分为实证和虚实夹杂证两种类型。目前，临床上治疗肾结石的药物较多，但由于肾脏的结构特殊，药物治疗的效果及药物的化石溶石功能不甚理想，多数病人不得以而转入手术治疗；而手术治疗往往伴有药物过敏等副作用，术后易复发，经济开支大，创伤大，治疗时间长，给病患带来严重的经济和身体负担。
发明内容
本发明所要解决的技术问题是为了克服现有技术的不足，提供一种治疗肾结石的中药，具有消炎止痛、活血化瘀、行气散结、利尿排石之功效，适用于有腰部酸痛、周身乏力、排尿不畅、血尿等症状的肾结石患者，且疗效显著，无毒副作用，成本低廉；配伍严谨，具有补充肾气，增加膀胱的气化功能，促使泌尿功能正常，产生溶石、排石的作用，且安全性高，有利于患者及时减轻疼痛症状。
本发明解决上述技术问题采用的技术方案是：一种治疗肾结石的中药，其特征在于，以重量百分比计由如下原料药制成：通淋草7～10％；猫须草4～6％；鸡肫草8～11％；陆英叶7～10％；萆薢9～12％；关木通6～9％；补骨脂2～5％；夏天无3～5％；木槿花2～5％；千日红4～7％；五味藤2～6％；忍冬藤2～5％；佛手3～6％；委陵菜2～4％；鸡矢藤2～4％；芦根2～5％；猪笼草3～5％；岗稔根3～5％；川朴4～6％，将上述原料药加水煎熬后去渣得滤液。
本发明的有益效果是，具有消炎止痛、活血化瘀、行气散结、利尿排石之功效，适用于有腰部酸痛、周身乏力、排尿不畅、血尿等症状的肾结石患者。
具体实施方式
下面结合实施例对本发明作进一步的描述：
实施例1：
采用通淋草、猫须草、鸡肫草、陆英叶、萆薢、关木通、补骨脂、夏天无、木槿花、千日红、五味藤、忍冬藤、佛手、委陵菜、鸡矢藤、芦根、猪笼草、岗稔根、川朴为原料而制成。其组分(重量％)每副为通淋草9.1、猫须草4.6、鸡肫草10.1、陆英叶9.2、萆薢10.8、关木通8.1、补骨脂3.2、夏天无3.8、木槿花3.2、千日红5.9、五味藤3.9、忍冬藤4.1、佛手5.1、委陵菜3.1、鸡矢藤2.0、芦根2.9、猪笼草3.1、岗稔根3.4、川朴4.4。取19味中草药总重量285克，加水1000ml浸泡2小时，煎3小时，去渣得滤液200ml，药渣再加水300ml，煎熬30-40分钟，去渣得滤液100ml，共得300ml药汁，装入无菌玻璃瓶内，密封瓶盖备用。每日1剂分2次口服，每次空腹温服150ml。5天为一疗程，中间休息2天，再进行下一疗程，一般服用3至5个疗程。
本发明通淋草具有清热解毒、镇痛消炎、利尿通淋等功效。对尿路结石、肝胆系结石及前列腺结石等结石顽症有显著疗效；猫须草用于治疗急慢性肾炎、膀胱炎、尿路结石和风湿性关节炎；鸡肫草补肺止咳，止血，利湿。主治肺热咳嗽，咯血，吐血，肾结石，胆结石，白带，湿热疮毒；陆英叶利尿消肿，活血止痛。用于肾炎水肿，腰膝酸痛；萆薢祛风，利湿。治风湿顽痹，腰膝疼痛，小便不利，淋浊，遗精，湿热疮毒；关木通热淋涩痛，水肿。能利水消肿，下利湿热，使湿热之邪下行从小便排出；补骨脂补肾壮阳，固精缩尿，肾虚腰痛，小便频数，小儿遗尿，肾漏，温脾止泻，纳气平喘；夏天无祛风湿，降血压。主治风湿性关节炎、腰肌劳损，高血压病，脑血管意外引起偏瘫；木槿花治风热束肺所致咳喘，血热妄行所致吐血衄血，尿血，肠风泻血等症，痢疾；千日红祛痰，平喘。用于慢性或喘息性支气管炎、百日咳，有止咳定喘、平肝明目功效；五味藤祛风除湿，散瘀止痛，跌打损伤，风湿骨痛，急性肠胃炎，过敏性皮炎；忍冬藤具有清热解毒，疏风通络的疗效。可用于温病发热，疮痈肿毒，热毒血痢，风湿热痹；佛手有理气化痰、止呕消胀、舒肝健脾、和胃功能；委陵菜解毒消肿，利湿止痒。用于痔疮，肛门肿痛，湿疹；鸡矢藤祛风除湿，消食化积，解毒消肿，活血止痛；芦根用于热病烦渴、胃热呕吐、肺热咳嗽、肺痈吐脓、热淋涩痛；猪笼草清肺润燥，行水，解毒。治肺燥咳嗽，百日咳，黄疸，胃痛；岗稔根养血，通络，止血止痛。用于慢性肝炎，疝气，崩漏，风湿痹痛，腰肌劳损；川朴主治：食积气滞，腹胀便秘，湿阻中焦，脘痞吐泻，痰壅气逆，胸满喘咳。
本发明各原料还可按下表所列比例(重量百分比)混合的实施例来实现。其加工工艺与实施例1相同。
下面结合我院进行的临床试验对本发明作进一步、详细地描述：
1、病例选择：作为治疗肾结石的中药制剂，选择确诊的肾结石患者200例临床观察，病人随机分成治疗组和对照组两组，治疗组100例，其中男性55例，女性45例，年龄30～60岁，平均年龄45.4岁，病程最短者1个月，最长者5年，平均2.5年。对照组100例，其中男性56例，女性44例，年龄31～65岁，平均年龄46.7岁，病程最短者2个月，最长者6年，平均3.1年。
2、治疗方法：每日1剂分2次口服，每次空腹温服150ml。5天为一疗程，中间休息2天，再进行下一疗程，服用5个疗程。对照组服用别嘌醇片，口服，一次1～3片，一日2～3次，饭前半小时或胃痛发作时嚼碎后服。
3、疗效判定：
(1)治愈：B超显示肾结石排出，体内无残留，肾功能恢复正常。
(2)显效：B超显示肾结石缩小，肾功能明显改善。
(3)有效：B超显示肾结石有所减小，肾功能改善或无继续恶化。
(4)无效：症状、体征无改善，肾功能无改善。
4、结果：
选用本发明中药制剂的治疗组中，治愈40例，显效30例，有效25例，无效5例，治愈率40％，总有效率95％。
对照组中治愈20例，显效15例，有效11例，无效54例，治愈率20％，总有效率46％。
以上结果显示，治疗组的治愈率和总有效率明显高于对照组。
典型病例：
1、许某，男，36岁，患者患肾结石有一年多，B超检查肾内结石为1.7×0.8cm，结石边缘光滑，经常腰痛，疼的时候吃点药症状会减轻，过一段时间又发作，反反复复发作。后来我院就诊，服用本发明中药制剂，服用2个疗程后，经B超检查，其肾内结石为1.0×0.5cm，腰痛明显减轻，又接着服用2个疗程后，经B超检查，其肾内结石已全部排出。
2、孙某，女，42岁，患者右侧后腰部绞痛，并向大腿根部放射，急性痛苦面容，呻吟、冷汗，查右下腹压痛(+)，右侧肾区压痛<++)，叩击痛(++)，舌苔薄黄，脉弦紧。急查B超：右肾窦内可见1.3cmX3.9cm的无回声区，右输尿管上段扩张，内可见直径0.5cm的强回声团，后方伴声影。尿常规：蛋白微量，白细胞3～5/np，红细胞20～30/np，诊断为石淋。治以排石通淋、清热利湿，服用本发明上述中药制剂，服用2个疗程后，随小便排出一枚黄豆大小的结石，服用3个疗程后，患者症状、体征消失，X线平片、B超显示结石阴影消失。
3、胡某，男，48岁，患者患有肾结石三余年，腰部和腹部经常会阵发性疼痛，有时剧烈活动后疼痛就会发作。
经B超检查，其肾内有结石5个，其中最大的1.2×0.7cm。后来我院就诊，服用本发明中药制剂，服用2个疗程后，经B超检查，其肾内结石还是5个，但结石明显变小，又接着服用本发明中药制剂1个疗程后，经B超检查，其肾内结石还有3个，但结石明显变小，又接着服用本发明的中药制剂1个疗程，经B超检查，其肾内结石已全部排出。

Claims (1)

1.一种治疗肾结石的中药，其特征在于，以重量百分比计由如下原料药制成：通淋草7～10％；猫须草4～6％；鸡肫草8～11％；陆英叶7～10％；萆薢9～12％；关木通6～9％；补骨脂2～5％；夏天无3～5％；木槿花2～5％；千日红4～7％；五味藤2～6％；忍冬藤2～5％；佛手3～6％；委陵菜2～4％；鸡矢藤2～4％；芦根2～5％；猪笼草3～5％；岗稔根3～5％；川朴4～6％，将上述原料药加水煎熬后去渣得滤液。
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