CN104490667A - Cosmetic containing loquat seed extract for preventing skin aging - Google Patents
Cosmetic containing loquat seed extract for preventing skin aging Download PDFInfo
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Abstract
The invention discloses a cosmetic containing a loquat seed extract for preventing skin aging. The cosmetic contains 0.001-20wt% of loquat seed extract, so that the cosmetic can play a role in preventing skin aging. The loquat seed extract contained in the cosmetic has an effect of inhibiting hyaluronidase and enhancing oxidation resistance, so that not only can synthesis of skin collagenous fiber cells be promoted, but also the skin elasticity can be further improved. Moreover, the loquat seed extract is a natural extract which is relatively good in stability and safety to skin, so that the loquat seed extract is added into the cosmetic for preventing skin aging and has a good skin care effect.
Description
Technical field
The invention belongs to cosmetic field, particularly relate to a kind of containing the anti-skin ageing cosmetics of Folium Eriobotryae seed extract.
Background technology
Substantially adopting to improve wrinkle of skin the free radical antioxidative functional suppressing ascorbic acid, alpha-tocopherol, retinol and derivant SOD thereof etc. in the market, also having to improve wrinkle of skin also with the use of cosmetics or pharmaceutical products.But these goods are expensive, and mostly be chemically active, safety is undesirable, does not also reach substantial effect.Therefore, develop natural safety better, improving effect significant cosmetics again to wrinkle of skin, is necessary.
Especially, improving wrinkle of skin object to reach, using retinoid (retinol and derivant thereof) etc. as the example of the anti-ageing composition of skin, No. 4603146th, U.S. Patent bulletin, in the patent such as No. 4877805, also have report.
This retinoid is to the improvement usefulness of skin, although there is certain effect by skin clinical identification, but there will be variable color, spoiled phenomenon in the formula of cosmetic product uses, using even if a small amount of also has side effect to skin, can bring out stimulation to skin.Meanwhile, also there is the phenomenon of effect instability in the application, the slight change of formula also can reduce the effect of retinoid, and in order to solve this technical problem, the research institution of many countries such as US and European, so far still in the research continued with in exploring.
In order to solve retinoid Problems existing in the application, we research and develop substitute that is natural, safety, explore the new cosmetic compositions with better anti-ageing effect.Using the material of natural safety to substitute retinoid, is the active substance utilizing natural materials self, solves the side-effect problem of retinoid to skin, and natural active substance has superior safety and the advantage of stability.
Folium Eriobotryae (Eriobotrya japonica) is aiphyllium belonging to Rosaceae, can by its fruit in the traditional Chinese medical science, and root, stem and leaf are used as medicine.Especially Folium Eriobotryae seed and Folium Eriobotryae are with lung heat clearing, reinforcing premodial qi, effect such as to reduce phlegm and well-known.In addition, Folium Eriobotryae seed extract has the Oxidation reducing active acid element and free radical, strengthen the report of oxidation resistance: (Yokota et al., Biol.Pharm.Bull.29 (3): 467-471 (2006)), Folium Eriobotryae seed extract and composition thereof is also had to have the effect of anti-inflammatory, the report that antioxidant activity etc. are relevant: (Shimizu et al., Chem.Pharm.Bull.34:2614-2617 (1986); De Tommaasi et al., Planta Med., 57:414-416 (1991)).
Summary of the invention
Object of the present invention to utilize natural active substance to realize cosmetic composition aging-resistant effect, and therefore, the invention provides a kind of containing the compositions of the anti-skin ageing of Folium Eriobotryae seed extract and the application in cosmetics, concrete scheme is as follows:
A compositions containing the anti-skin ageing of Folium Eriobotryae seed extract, it is characterized in that, the weight ratio that described compositions contains Folium Eriobotryae seed extract is 0.01 ~ 20%.
Preferably, the weight ratio that described compositions contains Folium Eriobotryae seed extract is 0.01 ~ 10%.
Further, the extracting method of described Folium Eriobotryae seed extract is: soaked by Folium Eriobotryae seed, to clean up and dry, to be driedly to zero gravity change, carries out physical property pulverizing; Folium Eriobotryae seed ground product and Extraction solvent are placed in the extraction equipment being furnished with reflux cooling device, are heated to 40-60 DEG C of reflux, extract, 5-9 hour; Extracting liquid filtering is removed insoluble matter and impurity; Freeze-dried after vacuum-concentrcted, obtain Folium Eriobotryae seed extract; Described Extraction solvent is anhydrous or moisture lower alcohol.
Preferably, described Folium Eriobotryae seed ground product and the weight ratio of Extraction solvent mixed liquor are 1:10-30, are preferably 1:20.
Preferably, described Extraction solvent is C
1-C
4alcohol, propylene glycol, distilled water is by weight mixing or C for 2:1:1
1-C
4alcohol, 1,3 butylene glycol, distilled water by weight for 2:1:1 mix.
The Folium Eriobotryae seed extract that described method obtains, can be applied to skin and prevent in aging cosmetics.A, described cosmetics, comprise following weight percent composition:
Surplus is deionized water.
Manufacture method is: Folium Eriobotryae seed extract, carbomer, EDETATE SODIUM, 1,3 butylene glycol, methyl hydroxybenzoate, deionized water are dissolved by above-mentioned percentage by weight mixing post-heating to 80 ± 2 DEG C, obtain aqueous phase; Propyl hydroxybenzoate, macadimia nut oil, white mineral oil, polydimethyl siloxane fluid, sad/certain herbaceous plants with big flowers acid glycerol three ester are dissolved by above-mentioned percentage by weight mixing post-heating to 80 ± 2 DEG C, obtains oil phase; Oil phase is added in aqueous phase and mixes, then triethanolamine is added hybrid cooling to 40-45 DEG C, add essence and continue hybrid cooling to 30-35 DEG C, obtain cosmetic composition.
B, described cosmetics, comprise following weight percent composition:
Manufacture method is: Folium Eriobotryae seed extract, glycerol, Anjidew NL50, deionized water are mixed to get aqueous phase by above-mentioned percentage by weight; Denatured alcohol, methyl hydroxybenzoate, propyl hydroxybenzoate are mixed to get alcohol phase by above-mentioned percentage by weight; Alcohol is added in aqueous phase and mixes, then add the rear filter paper filtering of essence mixing, obtain cosmetic composition.
C, preferred, described cosmetics, comprise following weight percent composition:
Manufacture method is: Folium Eriobotryae seed extract, carbomer, EDETATE SODIUM, 1,3 butylene glycol, methyl hydroxybenzoate, deionized water are dissolved by above-mentioned percentage by weight mixing post-heating to 80 ± 2 DEG C, obtain aqueous phase; Propyl hydroxybenzoate, macadimia nut oil, white mineral oil, polydimethyl siloxane fluid, sorbitan sesquioleate, polysorbate-60 are dissolved by above-mentioned percentage by weight mixing post-heating to 80 ± 2 DEG C, obtains oil phase; Oil phase is added in aqueous phase and mixes, then triethanolamine is added hybrid cooling to 40-45 DEG C, add essence and continue hybrid cooling to 30-35 DEG C, obtain cosmetic composition.
D, described cosmetics, comprise following weight percent composition:
Manufacture method is: Folium Eriobotryae seed extract, glycerol, hyaluronan extraction thing, methyl hydroxybenzoate, deionized water are dissolved by above-mentioned percentage by weight mixing post-heating to 80 ± 2 DEG C, obtain aqueous phase; Propyl hydroxybenzoate, lecithin, macadimia nut oil are dissolved by above-mentioned percentage by weight mixing post-heating to 80 ± 2 DEG C, obtains oil phase; Oil phase is added in aqueous phase and mixes, then add essence continuation hybrid cooling to 30-35 DEG C, obtain cosmetic composition.
The Folium Eriobotryae seed extract that the present invention obtains by the above method, toner/smoothing toner can be made an addition to, alimentary water, nourishing cream, essence, eye cream, massage creams etc. prevent in aging all relevant cosmetics, and addition is the 0.001-20% of cosmetic composition gross weight, and preferred addition scope is 0.01-10%, when addition is less than 0.001%, can not reaches and significantly prevent aging Expected Results; When addition is more than 20%, prevents aging effect and product stability aspect from not having too large change even if increase consumption again, the cost of product can be increased on the contrary, reduce economic benefit.
Specifically set forth content of the present invention below by way of testing, these experiments are just set forth to further illustrate content of the present invention, and interest field of the present invention is not by the restriction of these experiment described contents.
One, embodiment
(extracting the making of Folium Eriobotryae seed extract with different Extraction solvent)
By Folium Eriobotryae seed distilled water immersion, clean up, in cool place without under sunlit condition, after being dried to zero gravity change, grind with homogenizer.
(embodiment 1)
Ethanol and distilled water are mixed to get Extraction solvent by weight 3:1; The above-mentioned Folium Eriobotryae seed ground product 100g crushed is added in the Extraction solvent of 1500g, reflux, extract, 7 hours under 60 DEG C of temperature conditions; Then filter 1 time with 200 object filter cloths, carry out the 2nd time with whatman2 filter paper at ambient temperature and filter, remove insoluble matter and impurity; Then filtrate being placed in is furnished with the distillator of device for cooling, vacuum-concentrcted, freeze-dried under the condition of 50 DEG C, obtains the Folium Eriobotryae seed extract of 18.4g (dry weight).
(embodiment 2)
1,3 butylene glycol and distilled water are mixed to get Extraction solvent by weight 3:1; The above-mentioned Folium Eriobotryae seed ground product 100g crushed is added in the Extraction solvent of 1500g, reflux, extract, 7 hours under 60 DEG C of temperature conditions; Then filter 1 time with 200 object filter cloths, carry out the 2nd time with whatman2 filter paper at ambient temperature and filter, remove insoluble matter and impurity; Then filtrate being placed in is furnished with the distillator of device for cooling, vacuum-concentrcted, freeze-dried under the condition of 50 DEG C, obtains the Folium Eriobotryae seed extract of 14.6g (dry weight).
(embodiment 3)
Ethanol, 1,3 butylene glycol, distilled water are mixed to get Extraction solvent by weight 2:1:1; The above-mentioned Folium Eriobotryae seed ground product 100g crushed is added in the Extraction solvent of 1500g, reflux, extract, 7 hours under 60 DEG C of temperature conditions; Then filter 1 time with 200 object filter cloths, carry out the 2nd time with whatman2 filter paper at ambient temperature and cross elimination, except insoluble matter and impurity; Then filtrate being placed in is furnished with the distillator of device for cooling, vacuum-concentrcted, freeze-dried under the condition of 50 DEG C, obtains the Folium Eriobotryae seed extract of 16.2g (dry weight).
Two, test
Experiment 1: antioxidant effect measures
Antioxidant effect measures and adopts Fenton's reaction, lipid peroxidation (Lipid peroxidation system) and thiobarbituricacidα-method (TBA) test determination.
Folium Eriobotryae seed extract and each 0.01g of vitamin e of Example 1,2,3 are divided into four groups, arrange a blank group in addition; Each group adds 5ml respectively and contains Ethyl linoleate 0.01ml, 0.2% (mass fraction) dodecane sulfonate, iron chloride 10mmol, the buffer solution of hydrogen peroxide 2mol, 25mmol Tris and 0.75mmol potassium ion; After dissolving, each group adds 0.1ml dodecane methylsulfuric acid salt buffer solution again, under 55 DEG C of conditions, leave standstill 16 hours, adds after 4% (mass fraction) butylated hydroxytoluene 0.05ml reacts and leaves standstill.
Get each group of solution 0.3ml and put into test tube, add 0.05mol/L hydrochloric acid 3.0ml, butanols 4.0ml, under 535nm condition, measure absorbance by after its centrifugal layering, compare antioxidant effect, antioxidant effect computing formula is as follows:
Antioxidant effect=(test group absorbance-matched group absorbance)/matched group absorbance * 100%
Its result is as shown in table 1 below:
Table 1
| Test group | Antioxidant effect (%) |
| The extract that the ethanol of embodiment 1 and distilled water (3:1) extract | 77.5 |
| The extract that the 1,3 butylene glycol of embodiment 2 and distilled water (3:1) extract | 56.7 |
| The extract that the ethanol of embodiment 3,1,3 butylene glycol and distilled water (2:1:1) extract | 81.6 |
| Vitamin e | 45.2 |
Above table 1 shows, Folium Eriobotryae seed extract compares with vitamin e, shows more superior antioxidant effect; And the extract of the solvent extraction of 2:1:1 mixing pressed by Folium Eriobotryae seed ethanol, 1,3 butylene glycol and distilled water, show more superior antioxidant effect than the extract extracted with other Extraction solvent.
Test 2: collagen fiber cell biological synthetic effect measures
Directly take cell sample from human body, use above-described embodiment 1 respectively, the extract that embodiment 2 and embodiment 3 obtain, carry out process to measure promoting collagen fiber cell biological synthetic effect (namely adding the synthetic fibers cell of the culture fluid cultivation human body of flask volume 70-80% in culture flask) (normal human fibroblast:ATCC-28), Using such method embodiment 1, after the extract of embodiment 2 and embodiment 3 processes respectively, with collagen fiber cell biological synthesis mensuration test kit (the BCA protein assay kit bought on the market, pierce 23225), measure the collagen fiber cell generated.Each extract concentrations of adding in culture fluid is 0.01% (weight fraction) respectively, 0.1% (weight fraction), 1.00% (weight fraction).Its result is as shown in table 2 below:
Table 2
Upper table 2 shows, Folium Eriobotryae seed extract is conducive to collagen fiber cell biological synthetic ratio, can reach collagen fiber cell biological synthetic effect; And Folium Eriobotryae seed ethanol, 1,3 butylene glycol and distilled water extraction process, with compared with other Extraction solvent extraction process, the effect improving collagen fiber cell biological synthetic ratio is more obvious.Therefore, compositions of the present invention can promote that collagen fiber cell biological synthesizes, and for the wrinkle that aging particularly photoaging produces, uses cosmetic composition of the present invention to play and prevents aging action.
Experiment 3: suppress hyaluronidase effect measuring
Adopt hyaluronidase (sigma, 4) the activation degree effect of inactive enzyme is suppressed to measure, hyaluronidase decomposes to divide relevant hyaluronic a kind of enzyme to cellular water, if suppress the active effect of hyaluronidase to be given prominence to, hyaluronic stability is just high, the water holding capacity of cell is just high, can judge with this active effect suppressing hyaluronidase.
Respectively the extract 10mg of Example 1,2,3 adds in 3 test tubes, separately establishes the blank group that does not add extract; The acetate buffer solution 100ml adding 0.1mol/L in each test tube dissolves; In each group of acetate buffer solution, add enzyme (hyaluronidase) 0.1mg, place 20 minutes under 37 DEG C of conditions; Then adding the acetate buffer solution 250ml containing having dissolved hyaluronic acid 200mg, placing 40 minutes under 37 DEG C of conditions; Add the sodium hydroxide solution 100ml of 4mol/L again, after adding sodium hydroxide, solution temperature raises; Cooling solution, cooling procedure adds 100ml borate buffer (pH 9.0), after 20 minutes, under 585nm condition, measures absorbance to constant temperature when 37 DEG C.Inhibition is according to following formulae discovery:
Hyaluronic acid enzyme inhibition rate (%)=(test group absorbance-matched group absorbance)/matched group absorbance * 100%;
Its result is as shown in table 3 below:
Table 3
| Test group | Hyaluronic acid enzyme inhibition rate (%) |
| Embodiment 1 | 78 |
| Embodiment 2 | 65 |
| Embodiment 3 | 91 |
Upper table 3 result shows, Folium Eriobotryae seed extract can play the effect suppressing hyaluronidase, and Folium Eriobotryae seed ethanol, 1,3 ,-butanediol and distilled water are as the better effects if of Extraction solvent than the extract suppression hyaluronidase by other Extraction solvent extraction process.
Three, cosmetics experiment
1, the preparation of moisturizer
According to the amounts of components of each formula of following table 4, Folium Eriobotryae seed extract, carbomer, EDETATE SODIUM, 1,3 butylene glycol, methyl hydroxybenzoate, deionized water mixing post-heating to 80 ± 2 DEG C are dissolved, obtains aqueous phase; Propyl hydroxybenzoate, macadimia nut oil, white mineral oil, polydimethyl siloxane fluid, sad/certain herbaceous plants with big flowers acid glycerol three ester mixing post-heating to 80 ± 2 DEG C are dissolved, obtains oil phase; Oil phase is added in aqueous phase and mixes, then triethanolamine is added hybrid cooling to 45 DEG C, add essence and continue hybrid cooling to 35 DEG C, prepare moisturizer.
Table 4
2, comparative example moisturizer preparation
Formula based on Production Example 1 formula 3, the ethanol, 1 of embodiment 3 is replaced with pure water, the Folium Eriobotryae seed extract that 3-butanediol and distilled water (2:1:1) extract, other raw materials are constant, according to the same method preparing formula 1, formula 2, formula 3, prepare not containing the comparative example moisturizer of Folium Eriobotryae seed extract.
3, skin elasticity promotes effect measuring
Temperature 20-25 DEG C, under relative humidity 60% condition, selects the healthy women 30 (34 years old mean age) of more than 28 years old less than 40 years old to be divided into 4 groups:
The moisturizer that A group uses formula 1 to prepare containing Folium Eriobotryae seed extract;
The moisturizer that B group uses formula 2 to prepare containing Folium Eriobotryae seed extract;
The moisturizer that C group uses formula 3 to prepare containing Folium Eriobotryae seed extract;
D group uses not containing comparative example moisturizer prepared by Folium Eriobotryae seed extract;
Skin elasticity effect measuring is carried out to above four groups of user.
Above-mentioned cosmetic applying uses 12 weeks after (2 times/day) in circumference of eyes, uses skin elasticity analyzer (Cutometer SEM575, Courage+Khazaka
) measuring skin elasticity, measurement result is by following formulae discovery, and its each cell mean is as shown in table 5 below:
(R5)=R5 (12)-R5 (0); R5 value is the value that actual elastic coefficient (Net elasticity) shows, and more close to 1, elasticity is better.
Table 5
| Experimental group | Skin elasticity promotes effect (R5) |
| A group | 0.09 |
| B group | 0.05 |
| C group | 0.19 |
| D group | 0.015 |
Upper table 5 result shows, the moisturizer containing Folium Eriobotryae seed extract effectively can increase skin elasticity, and the moisturizer containing the Folium Eriobotryae seed extract that useful ethanol, 1,3 butylene glycol and distilled water extract as Extraction solvent increases the better effects if of skin elasticity.
4, Security test
The moisturizer of formula 1, formula 2, formula 3 preparation is applied to Medial upper arm skin, and situations such as observing skin whether have stimulation, erythema after 24 hours, itch, be irritated, observed once after 24 hours again.Observed result (calculating by positive reaction number of objects/total number of objects) is as shown in table 6 below:
Table 6
| Formula | After 24 hours | After 48 hours |
| Formula 1 | 0/30 | 1/30 |
| Formula 2 | 0/30 | 0/30 |
| Formula 3 | 0/30 | 0/30 |
The result of upper table 6 shows, moisturizer containing Folium Eriobotryae seed extract 8%, except having women's tested object (after 48 hours) except using the Folium Eriobotryae seed extract moisturizer of formula 1 and occurring positive reaction, all not there is positive reaction in the tested object of remaining, can determine that the cosmetic composition containing Folium Eriobotryae seed extract has good safety to skin by testing above.
5, the preparation of soft skin astringent
According to the amounts of components of each formula of following table 7, Folium Eriobotryae seed extract, glycerol, Anjidew NL50, deionized water are mixed to get aqueous phase; Denatured alcohol, methyl hydroxybenzoate, propyl hydroxybenzoate are mixed to get alcohol phase; Alcohol is added in aqueous phase and mixes, then add the rear filter paper filtering of essence mixing, obtain soft skin astringent.
Table 7
6, the preparation of nutrition astringent
According to the amounts of components of each formula of following table 8, Folium Eriobotryae seed extract, carbomer, EDETATE SODIUM, 1,3 butylene glycol, methyl hydroxybenzoate, deionized water mixing post-heating to 80 ± 2 DEG C are dissolved, obtains aqueous phase; Propyl hydroxybenzoate, macadimia nut oil, white mineral oil, polydimethyl siloxane fluid, sorbitan sesquioleate, polysorbate-60 are mixed post-heating to 80 ± 2 DEG C and dissolve, obtains oil phase; Oil phase is added in aqueous phase and mixes, then triethanolamine is added hybrid cooling to 40 DEG C, add essence and continue hybrid cooling to 35 DEG C, obtain nutrition astringent.
Table 8
7, the preparation of essence
According to the amounts of components of each formula of following table 9, Folium Eriobotryae seed extract, glycerol, hyaluronan extraction thing, methyl hydroxybenzoate, deionized water mixing post-heating to 80 ± 2 DEG C are dissolved, obtains aqueous phase; Propyl hydroxybenzoate, lecithin, macadimia nut oil mixing post-heating to 80 ± 2 DEG C are dissolved, obtains oil phase; Oil phase is added in aqueous phase and mixes, then add essence continuation hybrid cooling to 35 DEG C, obtain cosmetics essence.
Table 9
Effect of the present invention: the compositions containing Folium Eriobotryae seed extract provided by the invention can suppress hyaluronidase and strengthen antioxidative effect, not only can promote the synthesis of the biological thin bag of skin collagen fiber, can also improve elasticity of skin; And Folium Eriobotryae seed extract is natural extract, its stability and all better to the safety of skin, adds Folium Eriobotryae seed extract and has good skin effect in the cosmetic composition preventing skin ageing.
Detailed description of the invention
In order to more fully understand technology contents of the present invention, below in conjunction with specific embodiment technical scheme of the present invention being introduced further and illustrating.
In following examples, the extracting method of Folium Eriobotryae seed extract is as follows: by Folium Eriobotryae seed soak, clean up and In Shade drying, to be dried to zero gravity change after pulverize with homogenizer; Ethanol, propylene glycol and distilled water are mixed and made into Extraction solvent by weight for 2:1:1; Folium Eriobotryae seed ground product and Extraction solvent are placed in by weight for 1:20 the extraction equipment being furnished with reflux cooling device, are heated to 60 DEG C of reflux, extract, 7 hours; Extracting liquid filtering is removed insoluble matter and impurity; Freeze-dried after vacuum-concentrcted, obtain Folium Eriobotryae seed extract.
One, the preparation of moisturizer
Embodiment 1
By weight percentage, by the carbomer of the Folium Eriobotryae seed extract of 0.01-20%, 0.1-0.2%, the EDETATE SODIUM of 0.03-0.06%, 1 of 2-6%, 3-butanediol, 0.1-0.4% methyl hydroxybenzoate and required deionized water mixing post-heating to 80 ± 2 DEG C are dissolved, and obtain aqueous phase; By the polydimethyl siloxane fluid of the white mineral oil of the macadimia nut oil of the propyl hydroxybenzoate of 0.05-0.2%, 2-6%, 2-5%, 0.5-1.2%, 1-4% sad/certain herbaceous plants with big flowers acid glycerol three ester mixing post-heating to 80 ± 2 DEG C dissolve, and obtain oil phase; Added in aqueous phase by oil phase and mix, then the triethanolamine of 0.2-0.4% is added hybrid cooling to 40-45 DEG C, the essence adding 0.2-0.5% continues hybrid cooling to 30-35 DEG C, obtains cosmetics moisturizer.
Embodiment 2
By weight percentage, by the Folium Eriobotryae seed extract of 10%, 0.15% carbomer, the EDETATE SODIUM of 0.04%, 1,3 butylene glycol, 0.2% methyl hydroxybenzoate and required deionized water mixing post-heating to 80 ± 2 DEG C of 4% dissolve, obtain aqueous phase; By the propyl hydroxybenzoate of 0.15%, 4% macadimia nut oil, 3% white mineral oil, 0.7% polydimethyl siloxane fluid, 2% sad/certain herbaceous plants with big flowers acid glycerol three ester mixing post-heating to 80 ± 2 DEG C dissolve, and obtain oil phase; Added in aqueous phase by oil phase and mix, then the triethanolamine of 0.3% is added hybrid cooling to 40 DEG C, the essence adding 0.3% continues hybrid cooling to 35 DEG C, obtains cosmetics moisturizer.
Embodiment 3
By weight percentage, by the Folium Eriobotryae seed extract of 15%, 0.15% carbomer, the EDETATE SODIUM of 0.04%, 1,3 butylene glycol, 0.2% methyl hydroxybenzoate and required deionized water mixing post-heating to 80 ± 2 DEG C of 4% dissolve, obtain aqueous phase; By the propyl hydroxybenzoate of 0.15%, 4% macadimia nut oil, 3% white mineral oil, 0.7% polydimethyl siloxane fluid, 2% sad/certain herbaceous plants with big flowers acid glycerol three ester mixing post-heating to 80 ± 2 DEG C dissolve, and obtain oil phase; Added in aqueous phase by oil phase and mix, then the triethanolamine of 0.3% is added hybrid cooling to 40 DEG C, the essence adding 0.3% continues hybrid cooling to 35 DEG C, obtains cosmetics moisturizer.
Two, the preparation of soft skin astringent
Embodiment 4
By weight percentage, the Folium Eriobotryae seed extract of 0.01-20%, the glycerol of 0.5-2%, the Anjidew NL50 of 2-5% and required deionized water are mixed to get aqueous phase; The methyl hydroxybenzoate of the denatured alcohol of 8-12%, 0.05-0.2%, the propyl hydroxybenzoate of 0.01-0.05% are mixed to get alcohol phase; Alcohol is added in aqueous phase and mixes, then add the rear filter paper filtering of essence mixing of 0.05-0.1%, obtain the soft skin astringent of cosmetics.
Embodiment 5
By weight percentage, the Folium Eriobotryae seed extract of 10%, the glycerol of 1.5%, the Anjidew NL50 of 35% and required deionized water are mixed to get aqueous phase; The denatured alcohol of 10%, the methyl hydroxybenzoate of 0.15%, the propyl hydroxybenzoate of 0.2% are mixed to get alcohol phase; Alcohol is added in aqueous phase and mixes, then add the rear filter paper filtering of essence mixing of 0.08%, obtain the soft skin astringent of cosmetics.
Embodiment 6
By weight percentage, the Folium Eriobotryae seed extract of 15%, the glycerol of 1.5%, the Anjidew NL50 of 35% and required deionized water are mixed to get aqueous phase; The denatured alcohol of 10%, the methyl hydroxybenzoate of 0.15%, the propyl hydroxybenzoate of 0.2% are mixed to get alcohol phase; Alcohol is added in aqueous phase and mixes, then add the rear filter paper filtering of essence mixing of 0.08%, obtain the soft skin astringent of cosmetics.
Three, the preparation of nutrition astringent
Embodiment 7
By weight percentage, by the carbomer of the Folium Eriobotryae seed extract of 0.01-20%, 0.1-0.2%, the EDETATE SODIUM of 0.01-0.05%, 1 of 0.5-2%, the methyl hydroxybenzoate of 3-butanediol, 0.1-0.4% and required deionized water mixing post-heating to 80 ± 2 DEG C are dissolved, and obtain aqueous phase; The polysorbate-60 of the sorbitan sesquioleate of the polydimethyl siloxane fluid of the white mineral oil of the macadimia nut oil of the propyl hydroxybenzoate of 0.05-0.2%, 1-4%, 5-8%, 1-3%, 0.2-0.6%, 1.2-2% mixing post-heating to 80 ± 2 DEG C are dissolved, obtains oil phase; Added in aqueous phase by oil phase and mix, then the triethanolamine of 0.1-0.25% is added hybrid cooling to 40-45 DEG C, the essence adding 0.2-0.5% continues hybrid cooling to 30-35 DEG C, obtains cosmetics nutrition astringent.
Embodiment 8
By weight percentage, the Folium Eriobotryae seed extract of 10%, the carbomer of 0.15%, EDETATE SODIUM, the 1,3 butylene glycol of 1.5%, the methyl hydroxybenzoate of 0.3% and required deionized water mixing post-heating to 80 ± 2 DEG C of 0.03% are dissolved, obtains aqueous phase; By the propyl hydroxybenzoate of 0.15%, 2% macadimia nut oil, the white mineral oil of 7%, polydimethyl siloxane fluid, the sorbitan sesquioleate of 0.4%, the polysorbate-60 of 0.5% of 2% mix post-heating to 80 ± 2 DEG C and dissolve, obtain oil phase; Added in aqueous phase by oil phase and mix, then the triethanolamine of 0.2% is added hybrid cooling to 40 DEG C, the essence adding 0.3% continues hybrid cooling to 35 DEG C, obtains cosmetics nutrition astringent.
Embodiment 9
By weight percentage, the Folium Eriobotryae seed extract of 16%, the carbomer of 0.15%, EDETATE SODIUM, the 1,3 butylene glycol of 1.5%, the methyl hydroxybenzoate of 0.3% and required deionized water mixing post-heating to 80 ± 2 DEG C of 0.03% are dissolved, obtains aqueous phase; By the propyl hydroxybenzoate of 0.15%, 2% macadimia nut oil, the white mineral oil of 6%, polydimethyl siloxane fluid, the sorbitan sesquioleate of 0.4%, the polysorbate-60 of 0.5% of 2% mix post-heating to 80 ± 2 DEG C and dissolve, obtain oil phase; Added in aqueous phase by oil phase and mix, then the triethanolamine of 0.2% is added hybrid cooling to 40 DEG C, the essence adding 0.3% continues hybrid cooling to 35 DEG C, obtains cosmetics nutrition astringent.
Four, the preparation of essence
Embodiment 10
By weight percentage, the hyaluronan extraction thing of the glycerol of the Folium Eriobotryae seed extract of 0.01-20%, 6-10%, 2-3%, the methyl hydroxybenzoate of 0.1-0.2% and required deionized water mixing post-heating to 80 ± 2 DEG C are dissolved, obtains aqueous phase; The macadimia nut oil of the lecithin of the propyl hydroxybenzoate of 0.05-0.15%, 0.4-0.8%, 8-12% mixing post-heating to 80 ± 2 DEG C are dissolved, obtains oil phase; Oil phase is added in aqueous phase and mixes, then add 0.05-0.1% put into essence continue hybrid cooling to 30-35 DEG C, obtain cosmetics essence.
Embodiment 11
By weight percentage, by the Folium Eriobotryae seed extract of 10%, 8% glycerol, the hyaluronan extraction thing of 2.5%, the methyl hydroxybenzoate of 0.15% and required deionized water mixing post-heating to 80 ± 2 DEG C dissolve, obtain aqueous phase; The propyl hydroxybenzoate of 0.1%, the lecithin of 0.6%, macadimia nut oil mixing post-heating to 80 ± 2 DEG C of 10% are dissolved, obtains oil phase; Oil phase is added in aqueous phase and mixes, then add 0.08% put into essence continue hybrid cooling to 35 DEG C, obtain cosmetics essence.
Embodiment 12
By weight percentage, by the Folium Eriobotryae seed extract of 15%, 8% glycerol, the hyaluronan extraction thing of 2.5%, the methyl hydroxybenzoate of 0.15% and required deionized water mixing post-heating to 80 ± 2 DEG C dissolve, obtain aqueous phase; The propyl hydroxybenzoate of 0.1%, the lecithin of 0.6%, macadimia nut oil mixing post-heating to 80 ± 2 DEG C of 10% are dissolved, obtains oil phase; Oil phase is added in aqueous phase and mixes, then add 0.08% put into essence continue hybrid cooling to 35 DEG C, obtain cosmetics essence.
The above only further illustrates technology contents of the present invention with embodiment, so that reader is easier to understand, but does not represent embodiments of the present invention and is only limitted to this, and any technology done according to the present invention extends or recreation, all by protection of the present invention.
Claims (9)
1. the cosmetics containing the anti-skin ageing of Folium Eriobotryae seed extract, it is characterized in that, the percentage by weight that described cosmetics contain Folium Eriobotryae seed extract is 0.01 ~ 20%.
2. the cosmetics containing the anti-skin ageing of Folium Eriobotryae seed extract according to claim 1, it is characterized in that, described cosmetics also comprise following weight percent composition:
3. the cosmetics containing the anti-skin ageing of Folium Eriobotryae seed extract according to claim 1, it is characterized in that, described cosmetics also comprise following weight percent composition:
4. the cosmetics containing the anti-skin ageing of Folium Eriobotryae seed extract according to claim 1, it is characterized in that, described cosmetics also comprise following weight percent composition:
5. the cosmetics containing the anti-skin ageing of Folium Eriobotryae seed extract according to claim 1, it is characterized in that, described cosmetics also comprise following weight percent composition:
6. the cosmetics containing the anti-skin ageing of Folium Eriobotryae seed extract according to claim 1, it is characterized in that, the extracting method of described Folium Eriobotryae seed extract is:
Folium Eriobotryae seed is soaked, to clean up and dry, to be driedly to zero gravity change, carry out physical property pulverizing; Folium Eriobotryae seed ground product and Extraction solvent are placed in the extraction equipment being furnished with reflux cooling device, are heated to 40-60 DEG C of reflux, extract, 5-9 hour; Extracting liquid filtering is removed insoluble matter and impurity; Freeze-dried after vacuum-concentrcted, obtain Folium Eriobotryae seed extract; Described Extraction solvent is anhydrous or moisture lower alcohol.
7. the cosmetics containing the anti-skin ageing of Folium Eriobotryae seed extract according to claim 6, it is characterized in that, described Folium Eriobotryae seed ground product and the weight ratio of Extraction solvent mixed liquor are 1:10-30.
8. the cosmetics containing the anti-skin ageing of Folium Eriobotryae seed extract according to claim 6, it is characterized in that, described Folium Eriobotryae seed ground product and the weight ratio of Extraction solvent mixed liquor are 1:20.
9. the cosmetics containing the anti-skin ageing of Folium Eriobotryae seed extract according to claim 6, it is characterized in that, described Extraction solvent is C
1-C
4alcohol, propylene glycol, distilled water mix by weight 2:1:1, or C
1-C
4alcohol, 1,3 butylene glycol, distilled water mix by weight 2:1:1.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105213226A (en) * | 2015-10-26 | 2016-01-06 | 深圳市仙迪化妆品有限公司 | Cosmetic composition containing macadimia nut oil and preparation method thereof |
| CN106727064A (en) * | 2017-03-28 | 2017-05-31 | 佛山汇沐化学科技有限公司 | A kind of whitening Deacne pack |
| CN116172938A (en) * | 2023-03-15 | 2023-05-30 | 北京工商大学 | Preparation process of fritillary and loquat composition with relieving effect |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213226A (en) * | 2015-10-26 | 2016-01-06 | 深圳市仙迪化妆品有限公司 | Cosmetic composition containing macadimia nut oil and preparation method thereof |
| CN105213226B (en) * | 2015-10-26 | 2018-06-19 | 深圳市仙迪化妆品有限公司 | Cosmetic composition containing macadimia nut oil and preparation method thereof |
| CN106727064A (en) * | 2017-03-28 | 2017-05-31 | 佛山汇沐化学科技有限公司 | A kind of whitening Deacne pack |
| CN116172938A (en) * | 2023-03-15 | 2023-05-30 | 北京工商大学 | Preparation process of fritillary and loquat composition with relieving effect |
| CN116172938B (en) * | 2023-03-15 | 2024-05-03 | 北京工商大学 | Preparation process of fritillary and loquat composition with relieving effect |
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| CN104490667B (en) | 2017-08-08 |
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Address after: 518000, Guangdong, Baoan District, Fuyong Shenzhen street and show West Road, 44 sharp Industrial Park, 3, three or four floor Patentee after: Shenzhen Xiandi Cosmetics Co., Ltd Address before: 518000, Guangdong, Baoan District, Fuyong Shenzhen street and show West Road, 44 sharp Industrial Park, 3, three or four floor Patentee before: SHENZHEN SANDA COSMETICS Co.,Ltd. |
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