CN104474155A - Medicine for treating chronic cough and preparation method thereof - Google Patents
Medicine for treating chronic cough and preparation method thereof Download PDFInfo
- Publication number
- CN104474155A CN104474155A CN201410695051.0A CN201410695051A CN104474155A CN 104474155 A CN104474155 A CN 104474155A CN 201410695051 A CN201410695051 A CN 201410695051A CN 104474155 A CN104474155 A CN 104474155A
- Authority
- CN
- China
- Prior art keywords
- medicine
- chronic cough
- semen plantaginis
- carassius auratus
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 29
- 206010011224 Cough Diseases 0.000 title claims abstract description 26
- 208000013116 chronic cough Diseases 0.000 title claims abstract description 21
- 238000002360 preparation method Methods 0.000 title claims abstract description 8
- 229940079593 drug Drugs 0.000 title claims description 8
- 210000000582 semen Anatomy 0.000 claims abstract description 11
- 241000252229 Carassius auratus Species 0.000 claims description 10
- 238000009835 boiling Methods 0.000 claims description 4
- 238000005202 decontamination Methods 0.000 claims description 4
- 230000003588 decontaminative effect Effects 0.000 claims description 4
- 210000001835 viscera Anatomy 0.000 claims description 3
- 239000012467 final product Substances 0.000 claims description 2
- 239000002994 raw material Substances 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 6
- 206010062717 Increased upper airway secretion Diseases 0.000 abstract description 4
- 239000008280 blood Substances 0.000 abstract description 4
- 210000004369 blood Anatomy 0.000 abstract description 4
- 208000026435 phlegm Diseases 0.000 abstract description 4
- 210000000952 spleen Anatomy 0.000 abstract description 4
- 240000001398 Typha domingensis Species 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 230000003203 everyday effect Effects 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 206010019233 Headaches Diseases 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 231100000869 headache Toxicity 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 231100000820 toxicity test Toxicity 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 206010061245 Internal injury Diseases 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 206010013990 dysuria Diseases 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 238000003304 gavage Methods 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 208000006750 hematuria Diseases 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 201000002327 urinary tract obstruction Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/60—Fish, e.g. seahorses; Fish eggs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
Abstract
The invention discloses a medicine for treating chronic cough and a preparation method thereof. The medicine is mainly prepared from semen plantaginis and cattail according to a certain weight ratio, the medicine disclosed by the invention has the functions of clearing heat and eliminating phlegm, moistening dryness and cooling blood, tonifying spleen and decreasing internal heat, and has the advantages of quickness for becoming effective, good curative effect and no recurrence in treatment of chronic cough.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of chronic cough and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Namely chronic cough is coughed and prolongedly not to be healed, and goes out " Plain Questions coughs opinion ", coughs also known as chronic cough, chronic cough.How because exopathogen is reluctant to leave, internal organs internal injury, Qi and blood deficiency, caused by seven emotions pent-up etc.Because current Western medicine effectively cannot treat chronic cough, and long-term taking Western medicine has more side effect.Therefore, there is great demand in the Chinese medicine of people to rapid, effective treatment chronic cough, up to now, also do not find about relevant report of the present invention.
Summary of the invention
The present inventor is the checking repeatedly again through clinical trial on the basis of secret prescription handed down in the family from generation to generation, the finally perfect medicine of effective treatment chronic cough, thus completes the present invention.
Object of the present invention is just to provide a kind of Chinese medicine composition of more effective treatment chronic cough.
Another object of the present invention just there is provided the preparation method of this Chinese medicine composition.
Medicine of the present invention selects Semen Plantaginis, Herba Typhae, Carassius auratus to carry out combination preparation, made by these drug regimens each efficacy of drugs produce synergism, thus effectively can treat chronic cough.Semen Plantaginis is wherein selected to be that cold, enter kidney, urinary bladder channel, have diuretic, heat clearing away, improving eyesight, the function of eliminating the phlegm, controls urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, heat-damp in summer dysentery, cough ant phlegm, and arthralgia chiefly caused by damp pathogen, conjunctival congestion is hidden from view because its nature and flavor are sweet.Herba Typhae moisturizes removing heat from blood, goes taste to lie prostrate fire, controls dysuria, acute mastitis.Carassius auratus nature and flavor are sweet flat, and have the function of invigorating spleen to remove dampness, control weakness of the spleen and stomach, anorexia is unable, has blood in stool, edema.
Detailed description of the invention
The drug dose of instant component is also that inventor draws through groping in a large number to sum up, and the consumption of each component all has good curative effect within the scope of following weight
Semen Plantaginis 10-15g Herba Typhae 10-15g Carassius auratus 400-600g
Be preferably
Semen Plantaginis 15g Herba Typhae 15g Carassius auratus 500g
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Semen Plantaginis: pick decontamination, sieve removes spare, empty grain;
2, Herba Typhae: pick decontamination, cleans, dries;
3, Carassius auratus: remove internal organs and scale, cleans.
Two, prepare
The Semen Plantaginis of described weight, Herba Typhae, Carassius auratus are placed in crock, and the 1600 grams of intense fires of adding water decoct boilings 10 minutes, then with slow fire boiling to ripe and get final product.
Medicine of the present invention has heat clearing away and eliminates the phlegm, and moisturizes removing heat from blood, and the function of spleen invigorating pathogenic fire reducing is used for the treatment of chronic cough instant effect, good effect.
Set forth the beneficial effect of medicine of the present invention further below by way of test example, these tests comprise animal toxicity test and the clinical observation on the therapeutic effect test of medicine of the present invention.
The animal toxicity test of [test example 1] medicine of the present invention
Get West Germany rabbit 30, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, often organize 15, wherein one group is overdose test group, and another group is normal amount test group.Overdose test group is 25ml/kg, and normal amount is 10ml/kg, administering mode be administration by gavage to medicinal liquid, every day, secondary, serve on 7 days, observed administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's totally 31 examples for medical treatment.
2, diagnostic criteria
Clinical manifestation is generally without obvious pulmonary disease evidence, and continuous chronic cough Symptoms last was chronic cough more than 3 weeks, acutely during old property cough, with headache, and brain dusk.
3, Therapeutic Method
Select above-mentioned medicament, take to patient, patient need eat soup and eat fish, and every day, potion, 5 days was a course for the treatment of, took 2 courses for the treatment of continuously.
4, efficacy assessment standard
Effective: chronic cough symptom is fully recovered, recover normal;
Take a turn for the better: chronic cough symptom alleviates, continuous chronic cough and acutely coughing, the phenomenon with headache brain dusk disappears;
Invalid: not reach improvement standard person.
5, therapeutic outcome (seeing the following form):
In above-mentioned treatment, by Drug therapy chronic cough patient 31 example of the present invention, effective 26 examples of result, obvious effective rate is 83.87%, and take a turn for the better 3 examples, and improvement rate is 9.68%, and invalid 2 examples, total effective rate is 93.55%.
Claims (3)
1. treat a medicine for chronic cough, its feature is asked and is: it is made up of the crude drug in following weight range:
Semen Plantaginis 10-15g Herba Typhae 10-15g Carassius auratus 400-600g.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Semen Plantaginis 15g Herba Typhae 15g Carassius auratus 500g.
3. the preparation method of medicine according to claim 1 or 2, is characterized in that: it comprises the following steps:
(1) get the raw materials ready
(1) Semen Plantaginis: pick decontamination, sieve removes spare, empty grain;
(2) Herba Typhae: pick decontamination, cleans, dries;
(3) Carassius auratus: remove internal organs and scale, cleans;
(2) prepare
The Semen Plantaginis of described weight, Herba Typhae, Carassius auratus are placed in crock, and the 1600 grams of intense fires of adding water decoct boilings 10 minutes, then with slow fire boiling to ripe and get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410695051.0A CN104474155A (en) | 2014-11-27 | 2014-11-27 | Medicine for treating chronic cough and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410695051.0A CN104474155A (en) | 2014-11-27 | 2014-11-27 | Medicine for treating chronic cough and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104474155A true CN104474155A (en) | 2015-04-01 |
Family
ID=52748856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410695051.0A Pending CN104474155A (en) | 2014-11-27 | 2014-11-27 | Medicine for treating chronic cough and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104474155A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002096440A1 (en) * | 2001-05-31 | 2002-12-05 | Virendrakumar Jain | Cow urine therapy and herbal medicinal composition with cow urine and method of manufacturing the same |
| CN101869617A (en) * | 2009-04-27 | 2010-10-27 | 苏德才 | Traditional Chinese medicine for treating cough |
-
2014
- 2014-11-27 CN CN201410695051.0A patent/CN104474155A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002096440A1 (en) * | 2001-05-31 | 2002-12-05 | Virendrakumar Jain | Cow urine therapy and herbal medicinal composition with cow urine and method of manufacturing the same |
| CN101869617A (en) * | 2009-04-27 | 2010-10-27 | 苏德才 | Traditional Chinese medicine for treating cough |
Non-Patent Citations (3)
| Title |
|---|
| 杨保君: "《偏方巧治指南》", 30 April 1999, 中国纺织出版社 * |
| 武国忠: "《武国忠图说不上火保健康》", 31 July 2014, 江苏科学技术出版社 * |
| 王增: "《黑色食品食疗经》", 30 June 2006, 中国妇女出版社 * |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150401 |
|
| WD01 | Invention patent application deemed withdrawn after publication |