CN103142882A

CN103142882A - Gastrointestinal dysfunction treatment medicine and its preparation method

Info

Publication number: CN103142882A
Application number: CN2013100501937A
Authority: CN
Inventors: 安耀苍
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-02-08
Filing date: 2013-02-08
Publication date: 2013-06-12

Abstract

The invention discloses a gastrointestinal dysfunction treatment medicine and its preparation method. The gastrointestinal dysfunction treatment medicine is prepared through using purslane, coix seed, white hyacinth bean, Semen Euryales and the like according to certain weight proportions. The gastrointestinal dysfunction treatment medicine has the efficacies of intestine and stomach coordinating, spleen strengthening, stomach harmonizing, digestion helping, middle energizer regulating, stomach tonifying, and fluid promoting, and has the advantages of fast effectiveness, good curative effect, and high cure rate when the medicine is used for treating gastrointestinal dysfunction.

Description

A kind of medicine for the treatment of gastrointestinal dysfunction and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of the gastrointestinal function disorder and preparation method thereof, belong to the field of Chinese medicines.

Technical background

Functional gastrointestinal disorder; claim again gastrointestinal neurosis; it is the general name of one group of gastro-intestinal syndrome; Nervous and Mental Factors is this pathogenetic main inducing; as the difficulty in nervous, anxiety, life and work, worry, unexpected misfortune etc.; all can disturb the normal activity of higher nerve, and then cause the gastrointestinal dysfunction.Clinical manifestation mainly contains globus hystericus, nervous vomiting, eroetatio nervosa, anorexia nervosa and irritable bowel syndrome, often with insomnia, anxiety, attention lax, other functional symptoms such as forgetful, nervousness, headache.The background of many spiritednesses factor, aspect biochemistry and pathological anatomy without organic change.This disease does not comprise the functional gastrointestinal disorder that the other system disease causes.Chinese medicine to the record of primary disease sporadically appear in melancholia, Bulbus Lilii syndrome, globus hystericus, belch, vomiting, gastric abscess, indigestion and loss of appetite, abdominal distention, suffer from abdominal pain, have loose bowels, constipation and other diseases.Onset is mostly slow, and the course of disease can be for years on end, and morbidity is persistence or outbreak repeatedly.At present, because Western medicine is can't the rapid, effective treatment gastrointestinal function disorderly, and a lot of side effect are arranged, therefore, there is very large demand in people to the Chinese medicine of rapid, effective treatment gastrointestinal function disorder.

Summary of the invention

The inventor has finally found the medicine of effective treatment gastrointestinal function disorder, thereby has completed the present invention according to the research of theory of Chinese medical science and clinical repeatedly test and checking.

Purpose of the present invention just is to provide a kind of composition of medicine that can effectively treat the gastrointestinal function disorder.

Another object of the present invention just has been to provide the preparation method of this composition of medicine.

Medicine of the present invention selects Herba Portulacae, Semen Coicis, Rhizoma Dioscoreae, Semen Lablab Album, Semen Euryales, Folium Nelumbinis medicine to make up, and makes each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat the gastrointestinal function disorder.Wherein select Herba Portulacae to be because its nature and flavor acid is cold, enter large intestine, liver, spleen channel, heat-clearing and toxic substances removing is arranged, the function of loose blood detumescence is controlled the hematodiarrhoea pus and blood, pyretic stranguria, stranguria with blood, leukorrhagia, carbuncle malignant boil, erysipelas, scrofula.Select Semen Coicis to be because its property slightly sweet flavor is cool, enter spleen, lung, kidney channel, spleen invigorating is arranged, tonifying the lung, heat clearing away, the function of dampness removing is controlled and is had loose bowels, arthralgia chiefly caused by damp pathogen, the contracture of muscle arteries and veins, joint stuffiness, edema, beriberi, consumptive lung disease, lung abscess, acute appendicitis, stranguria with turbid discharge, leucorrhea.Select Rhizoma Dioscoreae to be because its nature and flavor are sweet, flat, enter lung, spleen, kidney channel, spleen invigorating is arranged, tonifying the lung is reinforced the kidney, and the function of benefit essence is controlled diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease is quenched one's thirst, seminal emission, leukorrhagia, frequent micturition.Select Semen Lablab Album to be because its nature and flavor are sweet, tepor is returned spleen, stomach warp, and invigorating the spleen for eliminating dampness is arranged, and in the function of relieving summer heat, control weakness of the spleen and stomach, inappetence, diarrhea, leukorrhagia, heat-damp in summer is vomited and diarrhoea, abdominal distention uncomfortable in chest.Select Semen Euryales to be because its property sweet-puckery flavor is flat, enter spleen, kidney channel, reinforcing the kindey to control nocturnal emission is arranged, the spleen reinforcing stopping leak is controlled seminal emission, stranguria with turbid discharge, leukorrhagia, incontinence of urine, loose stool and diarrhea.Select Folium Nelumbinis to be because its nature and flavor are pained, flat, enter the heart, liver, spleen channel, clearing away summer-heat and eliminating dampness is arranged, sending up the lucid YANG, the function of hemostasis is controlled diarrhea due to summer heat and dampness, dizzy, the aqueous vapor edema, thunder-headache is spitted blood, epistaxis, metrorrhagia is had blood in stool, puerperal blood faints.

The specific embodiment

The drug dose of the present invention's combination is also that the inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect in the following weight scope

Herba Portulacae 15-30 gram Semen Coicis 15-30 Keshan medicine 25-35 gram

Seem Lablab Album 10-20 gram Semen Euryales 10-20 gram Folium Nelumbinis 3-6 gram

Preferable amount is

Herba Portulacae 25 gram Semen Coicis 25 Keshan medicine 30 grams

Seem Lablab Album 15 gram Semen Euryales 15 gram Folium Nelumbinis 5 grams

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Herba Portulacae: choose clean impurity, remove undesirable root, slightly moisten with water, cutting is dried;

2, Semen Coicis: get crude drug, remove residual cot, impurity;

3, Rhizoma Dioscoreae: choose clean impurity, be soaked in water and pull out and slightly dry in the air for degree to the Rhizoma Dioscoreae central part is softening, section is dried or is dried;

4, Semen Lablab Album: get crude drug, remove mould, moth Semen Lablab Album grain and impurity, the used time smashs to pieces

5, Semen Euryales: first rise frying in wheat bran heat release pot to cigarette, cleaner Semen Euryales is poured into, stir to little yellow, take out, the well sifted wheat bran cools;

6, Folium Nelumbinis: clean with water, cut off the base of a fruit and edge, shredding is dried.

Two, preparation

1, Herba Portulacae, Semen Coicis, Rhizoma Dioscoreae, Semen Lablab Album, Semen Euryales, the Folium Nelumbinis medicine of described weight are put into container, grind into powder.

2, fine drug powder is added 300 ml milks, mix thoroughly and be potion, each serving potion, mix again when taking.

Medicine of the present invention has the intestines and stomach coordinating, invigorating the spleen and regulating the stomach, help digestion transfer in, the effect of reinforcing stomach reg fluid, the disorderly instant effect for the treatment of gastrointestinal function, short treating period do not recur.

Below further set forth the beneficial effect of medicine of the present invention by test example, these tests comprise animal toxicity test report and the clinical observation material of medicine of the present invention.

The animal toxicity test report of [test example 1] medicine of the present invention

Get 30 of rabbit, male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, 15 every group, wherein one group is the normal amount toxicity test, another group is the super quantity toxicity test, and the normal amount group is 15ml/kg, and the excess group is 30ml/kg, administering mode is the administration by gavage administration, be used in conjunction 7 days every day twice, observes the administration reaction every day, it is normal that result of the test shows that two groups of families exempt from diet activity, and medicine is without bad toxic and side effects.

The clinical observation material of [test example 2] medicine of the present invention

1, physical data

Accept out-patient's 100 examples for medical treatment, male patient's 65 examples, female patient 35 examples.

2, diagnostic criteria

How slow the gastrointestinal dysfunction onset is, and how touching the course of disease is with the passing of time, and complicated symptoms is persistence or repeated relapsing.Clinical manifestation is take gastrointestinal symptom as main, stomach autonomic nervous dysfunction's patient shows as more: the dim gas of seriality that repeatedly shows effect, the foreign body in pharynx sense, the feeling of distension and oppression of both sides of the chest and gastral cavilty section, string pain, and gastric is difficult to say the sense of discomfort of shape, without hunger sensation or the time and honey stomach, Shi Erwu appetite, gastric upper punch superinverse, have the hiccups, xerostomia, bitter taste, uncomfortable in chest, like long gas, acid regurgitation, belch, anorexia, feel sick, glutted after burning sensation, food under vomiting, xiphoid-process, epigastric discomfort or pain, emotion changes sx↑ whenever.

The gastrointestinal nerve dysfunction is the modal functional disease of gastrointestinal tract.Take bowel symptoms as main, the patient often has stomachache, abdominal distention, borborygmus, diarrhoea and constipation, left lower quadrant, and pain the time can be laid one's hand on and streak swollen thing, and stomachache often increases the weight of because of feed or cold drink, alleviates after defecation, aerofluxus, coloclysis.Stomachache often with abdominal distention, defecation freely sense or defecation frequency increase, feces such as can rarely do at the symptom.Claim that in the past this is colon dysfunction, spastic colon, adaptive colitis, spastic colitis, mucous colitis, emotional diarrhea etc.

3, Therapeutic Method

Select above-mentioned medicament, take to the patient, morning every day, evening respectively take 1 time, and 7 days is a course for the treatment of, takes continuously 5 courses for the treatment of.

4, efficacy assessment standard

Produce effects: transference cure, body constitution recover normal, observe 1 year without the recidivist;

Take a turn for the better: symptom is clearly better, and body constitution is recovered gradually.

Invalid: as not reach improvement standard person.

5, therapeutic outcome (seeing the following form)

In above-mentioned treatment, with disorderly patient's 100 examples of Drug therapy gastrointestinal function of the present invention, produce effects 97 examples as a result, obvious effective rate is 97%, 2 examples that take a turn for the better, improvement rate is 2%, invalid 1 example, total effective rate is 99%.

Claims

1. medicine for the treatment of gastrointestinal dysfunction, it is characterized in that: it is to be made by the crude drug in following weight range:

Herba Portulacae 15-30 gram Semen Coicis 15-30 Keshan medicine 25-35 gram

Seem Lablab Album 10-20 gram Semen Euryales 10-20 gram Folium Nelumbinis 3-6 gram.

2. treat according to claim 1 the medicine of gastrointestinal dysfunction, wherein the consumption of each crude drug is:

Herba Portulacae 25 gram Semen Coicis 25 Keshan medicine 30 grams

Seem Lablab Album 15 gram Semen Euryales 15 gram Folium Nelumbinis 5 grams.

3. the preparation method of described medicine according to claim 1 and 2, it comprises the following steps:

(1) get the raw materials ready

(1) Herba Portulacae: choose clean impurity, remove undesirable root, slightly moisten with water, cutting is dried;

(2) Semen Coicis: get crude drug, remove residual cot, impurity;

(3) Rhizoma Dioscoreae: choose clean impurity, be soaked in water and pull out and slightly dry in the air for degree to the Rhizoma Dioscoreae central part is softening, section is dried or is dried;

(4) Semen Lablab Album: get crude drug, remove mould, moth Semen Lablab Album grain and impurity, the used time smashs to pieces

(5) Semen Euryales: first rise frying in wheat bran heat release pot to cigarette, cleaner Semen Euryales is poured into, stir to little yellow, take out, the well sifted wheat bran cools;

(6) Folium Nelumbinis: clean with water, cut off the base of a fruit and edge, shredding is dried;

(2) preparation

(1) Herba Portulacae, Semen Coicis, Rhizoma Dioscoreae, Semen Lablab Album, Semen Euryales, the Folium Nelumbinis medicine of described weight are put into container, grind into powder;

(2) fine drug powder is added 300 ml milks, mix thoroughly and be potion, each serving potion, mix again when taking.