CN104436077A - Medicine composition for treating mammary gland proliferation - Google Patents
Medicine composition for treating mammary gland proliferation Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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Abstract
The invention discloses a medicine composition for treating mammary gland proliferation, and belongs to the technical field of Chinese medicines. The medicine composition comprises, by weight, 5-15 parts of radix bupleuri, 10-20 parts of white peony roots, 10-20 parts of angelica, 5-15 parts of curcuma zedoary, 10-20 parts of seaweeds, 10-15 parts of corydalis tuber, 5-15 parts of green tangerine peel and 5-20 parts of rhizoma cyperi. Based on the principle of combining disease identification and syndrome differentiation for treating mammary gland proliferation by traditional Chinese medicines, the medicine composition treats both symptoms and root causes and treats excess and deficiency, natural plant medicines for soothing the liver, regulating qi, resolving hard lumps, regulating thoroughfare and conception vessels and promoting blood circulation and stopping pain are screened, herbal medicines in a prescription are precisely and appropriately combined, and the medicine composition is obvious and stable in curative effect and low in cost and has no adverse effects from observation in the long-term and short-term clinical application process.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of pharmaceutical composition for the treatment of cyclomastopathy.
Background technology
Cyclomastopathy is the disease that the growth of mammary gland tissue conduit and newborn lobule degeneration structurally and Progressive symmetric erythrokeratodermia connective tissue causes, and its pathogenic factor is mainly due to endocrine hormone imbalance.Be characterized in periodically mastalgia, the single or multiple lump of companion's one or both sides breast.The traditional Chinese medical science belongs to " nodules of the breast ", " mastalgia " category.Cyclomastopathy is the common cystic hyperplasia of breast of women, and its sickness rate accounts for the first place of mastopathy, and this sick sickness rate was in the trend risen year by year in the last few years, and the age also more and more becomes younger.About there is the women of 70% ~ 80% to have cyclomastopathy in various degree according to investigations, be more common in the women of 25 ~ 45 years old.Real pathogenic factor is also indefinite so far, but a large amount of clinical observation display, and cyclomastopathy may be unbalanced with hormone in vivo level or mammary gland tissue is more relevant to the sensitivity of gonadal hormone.Research in recent years thinks relevant with endocrine disturbance and Nervous and Mental Factors.When under the effect of body in some stressors (as work is too nervous, emotion is too exciting, advanced age is unmarried, not suckling in puerperal and suffer from some chronic disease etc.), the breast hyperplasia tissue that the acinus of breast, glandular tube and fibrous tissue should be restored can not get restoring or meromorphosis, just form cyclomastopathy gradually, show as the newborn leaf and nodular particles and the pain that occurs together that thicken.
The traditional Chinese medical science to the understanding of cyclomastopathy comparatively early, namely has " breast knot is swollen " from Shanxi for Liu Juan work Remedies Left Over by Ghosts is contained, begins to claim " nodules of the breast " to Qing Dynasty Gao Jinting " Yangke Xinde Ji, Experience Gained in Treating External Diseases ".Think that the liver pulse cloth breast is coerced, nipple color green grass or young crops belongs to liver, if depression of liver-QI, breast side of body venation is obstructed, breast functional activity of QI being not smooth, therefore sees distending pain of the breast.Breast is passed through by the stomach channel of foot-Yang-ming again, a lot of many blood of Yangming Channel, and breast is the histoorgan of milk circulation, easy stagnation of QI blood stasis congelation in bulk and pain, with 500 routine nodules of the breast patients statistics, find being irritable and irascible person 374 people, account for 74.6%, illustrate this disease and liver stomach in close relations.In addition, from 317 routine cyclomastopathy patients, it is routine that gynecological is diagnosed as menoxenia, dysmenorrhea, hysteromyoma, cervical erosion and pelvic inflammatory disease etc. 228, accounts for 71.93%.Menstruation and breast indicate femaleness, menstruation on time and under, breast changes with menstruation, and mechanism of qi is unobstructed, and both live in peace with each other, if functional activity of QI being not smooth, must cause qi depression to blood stasis caking and pain.Thus illustrate depression of liver-QI be pathogenic principal element, and involve punching appoint and taste.
Modern medicine is to the Drug therapy of cyclomastopathy mainly based on endocrine regulation and symptomatic treatment, and as bromocriptine, regulate the tamoxifen of female hormone, Progesterone and methyl testosterone etc., available 5% potassium iodide is treated under physician guidance in addition.But primary disease has periodically and the feature of recurrent exerbation, and above-mentioned Western medicine side effect is large, can not long-term taking.
Summary of the invention
In order to overcome the defect that above-mentioned prior art exists, the object of the present invention is to provide a kind of pharmaceutical composition for the treatment of cyclomastopathy, this pharmaceutical composition is evident in efficacy, toxic and side effects is little, with low cost.
The present invention is achieved through the following technical solutions:
Treat a pharmaceutical composition for cyclomastopathy, be made up of the crude drug of following mass parts: Radix Bupleuri 5 ~ 15 parts, the Radix Paeoniae Alba 10 ~ 20 parts, Radix Angelicae Sinensis 10 ~ 20 parts, Rhizoma Curcumae 5 ~ 15 parts, Sargassum 10 ~ 20 parts, Rhizoma Corydalis 10 ~ 15 parts, 5 ~ 15 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 5 ~ 20 parts.
Treat a pharmaceutical composition for cyclomastopathy, be made up of the crude drug of following mass parts: Radix Bupleuri 10 ~ 15 parts, the Radix Paeoniae Alba 10 ~ 20 parts, Radix Angelicae Sinensis 10 ~ 20 parts, Rhizoma Curcumae 10 ~ 15 parts, Sargassum 10 ~ 20 parts, Rhizoma Corydalis 10 ~ 15 parts, 9 ~ 15 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 10 ~ 20 parts.
Treat a pharmaceutical composition for cyclomastopathy, be made up of the crude drug of following mass parts: Radix Bupleuri 10 parts, the Radix Paeoniae Alba 15 parts, Radix Angelicae Sinensis 15 parts, Rhizoma Curcumae 10 parts, Sargassum 10 parts, Rhizoma Corydalis 12 parts, 9 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 10 parts.
Treat a pharmaceutical composition for cyclomastopathy, be made up of the crude drug of following mass parts: be made up of the following ingredients crude drug in units of mass parts: Radix Bupleuri 12 parts, the Radix Paeoniae Alba 15 parts, Radix Angelicae Sinensis 15 parts, Rhizoma Curcumae 10 parts, Sargassum 15 parts, Rhizoma Corydalis 15 parts, 9 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 12 parts.
Treat a pharmaceutical composition for cyclomastopathy, be made up of the crude drug of following mass parts: Radix Bupleuri 12 parts, the Radix Paeoniae Alba 20 parts, Radix Angelicae Sinensis 20 parts, Rhizoma Curcumae 15 parts, Sargassum 20 parts, Rhizoma Corydalis 10 parts, 12 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 15 parts.
Treat a pharmaceutical composition for cyclomastopathy, be made up of the crude drug of following mass parts: Radix Bupleuri 9 parts, the Radix Paeoniae Alba 12 parts, Radix Angelicae Sinensis 12 parts, Rhizoma Curcumae 9 parts, Sargassum 10 parts, Rhizoma Corydalis 12 parts, 9 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 9 parts.
Treat a pharmaceutical composition for cyclomastopathy, be made up of the crude drug of following mass parts: Radix Bupleuri 5 parts, the Radix Paeoniae Alba 20 parts, Radix Angelicae Sinensis 20 parts, Rhizoma Curcumae 5 parts, Sargassum 15 parts, Rhizoma Corydalis 10 parts, 5 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 5 parts.
With described pharmaceutical composition for medicinal ingredient, add adjuvant and make oral formulations.Described oral formulations is tablet, powder, pill, capsule, granule, electuary or oral liquid.Described adjuvant comprises one or more in stabilizing agent, solubilizing agent, lubricant or disintegrating agent.
Compared with prior art, the present invention has following useful technique effect:
The present invention be directed to easy repeatedly, the periodic feature of cyclomastopathy chronic disease, through medicine optimization experiment repeatedly and clinical practice accumulation, the Chinese medicine prescription formed and proportioning, pharmaceutical composition of the present invention based on the differential diagnosis of diseases of Mammary Hyperplasia Treated by Chinese Medicine and the dialectical principle that combines, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, filter out the natural plant of depressed liver-energy dispersing and QI regulating, hard masses softening and resolving, Chong and Ren Meridians regulating, promoting blood circulation and stopping pain, flavour of a drug combination is precise and appropriate, determined curative effect, stable, low cost.Married woman take blood as this, and meanwhile, qi as the commander of blood, blood being the mother of qi, and both QI and blood all derive from the raw essence of water and grain of internal organsization, follows row in passages through which vital energy circulates system.So married woman's QI and blood fill, run and suitable, then through, pregnant, produce, breast etc. process safety.Otherwise the qi and blood disorder that a variety of causes causes is the immanent cause of gynaecopathia.Therefore pharmaceutical composition of the present invention is also studied from adjusting pleasant blood to start with.We are with Radix Bupleuri, the Radix Paeoniae Alba, Radix Angelicae Sinensis three medicine for monarch, and Radix Bupleuri is soothing the liver strongly fragrant gas, Radix Angelicae Sinensis, the Radix Paeoniae Alba take a tonic or nourishing food to build up one's health deficiency of liver-blood.With the passing of time breast QI and blood is smooth is agglomerated into caking, when the weight product with blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, therefore get Rhizoma Curcumae, Sargassum is minister, the condensation of the blood that degass.Be aided with Pericarpium Citri Reticulatae Viride for assistant, help the unobstructed QI and blood of Radix Bupleuri.Stagnation of QI and blood may bring about pain, the common pain of nodules of the breast patient clinical, therefore with Rhizoma Cyperi, Rhizoma Corydalis for making, coordinating Radix Angelicae Sinensis, the Radix Paeoniae Alba, helping blood-activating and qi-promoting analgesic effect better.The present invention verifies through clinical practice, and many cases disease all has no adverse reaction.Sum up through a large amount of clinical efficacy, the recent cure rate of pharmaceutical composition of the present invention is 65%, and total effective rate is 95%, and clinical trial does not find 1 routine untoward reaction case history, is the Chinese medicine formula medicine of ideal treatment cyclomastopathy (nodules of the breast).
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in further detail, and the explanation of the invention is not limited.
Pharmaceutical composition of the present invention is based on the differential diagnosis of diseases of Mammary Hyperplasia Treated by Chinese Medicine and the dialectical principle that combines, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, filter out the natural plant of depressed liver-energy dispersing and QI regulating, hard masses softening and resolving, Chong and Ren Meridians regulating, promoting blood circulation and stopping pain, according to theory of Chinese medical science prescription, be prepared from according to certain weight proportion.
A kind of pharmaceutical composition for the treatment of cyclomastopathy of the present invention, is made up of the crude drug of following mass parts: Radix Bupleuri 5 ~ 15 parts, the Radix Paeoniae Alba 10 ~ 20 parts, Radix Angelicae Sinensis 10 ~ 20 parts, Rhizoma Curcumae 5 ~ 15 parts, Sargassum 10 ~ 20 parts, Rhizoma Corydalis 10 ~ 15 parts, 5 ~ 15 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 5 ~ 20 parts.
Function: depressed liver-energy dispersing and QI regulating, hard masses softening and resolving, promoting blood circulation and stopping pain, Chong and Ren Meridians regulating.
Foundation: the traditional Chinese medical science thinks that cyclomastopathy (nodules of the breast) mostly is depression of liver-QI, qi depression to blood stasis, Chong and Ren channel disorder causes, the product of application depressed liver-energy dispersing and QI regulating, hard masses softening and resolving, promoting blood circulation and stopping pain and Chong and Ren Meridians regulating, according to card medication, as Radix Bupleuri depressed liver-energy dispersing and QI regulating, Rhizoma Curcumae, Sargassum hard masses softening and resolving, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae Viride blood circulation promoting regulates qi blood stasis dispelling, and Chong and Ren Meridians regulating.
Embodiment 1
The pharmaceutical composition for the treatment of cyclomastopathy, in mass parts: Radix Bupleuri 10 parts, the Radix Paeoniae Alba 15 parts, Rhizoma Curcumae 10 parts, Sargassum 10 parts, Rhizoma Corydalis 12 parts, 9 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 10 parts.
Embodiment 2
The pharmaceutical composition for the treatment of cyclomastopathy, in mass parts: Radix Bupleuri 12 parts, the Radix Paeoniae Alba 15 parts, Radix Angelicae Sinensis 15 parts, Rhizoma Curcumae 10 parts, Sargassum 15 parts, Rhizoma Corydalis 15 parts, 9 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 12 parts.
Embodiment 3
The pharmaceutical composition for the treatment of cyclomastopathy, in mass parts: Radix Bupleuri 12 parts, the Radix Paeoniae Alba 15 parts, Radix Angelicae Sinensis 15 parts, Rhizoma Curcumae 10 parts, Sargassum 15 parts, Rhizoma Corydalis 15 parts, 9 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 12 parts.
Embodiment 4
The pharmaceutical composition for the treatment of cyclomastopathy, in mass parts: Radix Bupleuri 12 parts, the Radix Paeoniae Alba 20 parts, Radix Angelicae Sinensis 20 parts, Rhizoma Curcumae 15 parts, Sargassum 20 parts, Rhizoma Corydalis 10 parts, 12 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 15 parts.
Embodiment 5
The pharmaceutical composition for the treatment of cyclomastopathy, in mass parts: Radix Bupleuri 5 parts, the Radix Paeoniae Alba 20 parts, Radix Angelicae Sinensis 20 parts, Rhizoma Curcumae 5 parts, Sargassum 15 parts, Rhizoma Corydalis 10 parts, 5 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 5 parts.
Aforementioned pharmaceutical compositions of the present invention adds various customary adjuvant required when preparing different dosage form, such as disintegrating agent, lubricant, binding agent etc. are prepared into the conventional oral formulations of any one with the method for Chinese medicinal of routine, such as, can be pill, capsule, tablet, powder, granule, electuary or oral liquid etc.
The present invention's herbal raw material used all can be buied from Chinese medicine shop, and its specification meets national medical standards.
Usage and consumption:
Dosage of the present invention depends on concrete dosage form, the age of patient, the factor such as body weight and health status.As guidance: for oral administration: 1) capsule: take 3 every day, each serving 2-4 grain, every content of dispersion 0.4g, warm water takes.2) tablet: take 3 every day, each serving 2-4 sheet, every sheet content of dispersion 0.4g, warm water takes.3) pill: take 3 every day, each serving 8g, warm water takes.4) electuary: take 3 every day, each serving 10g, warm water takes.
Provide the concrete use embodiment that the present invention obtains pharmaceutical composition below:
The present invention adds up the clinical 200 routine patients chosen, and patient age is between 25 ~ 45 years old; The course of disease 3 months ~ 10 years; All patients all have breast diffusivity dull pain in various degree or distending pain symptom, have obvious periodicity, how exacerbation of symptoms before menstrual onset, and pain relief or disappearance after menstruation.The visible cyclomastopathy in various degree of ultrasound diagnosis, quality is medium, obscure boundary; Noctovisor scan inspection display breast local transparent degree is low, and vascular lake increases, and in netted change, blood vessel is fuzzy.
Curative effect judgment criteria:
Effective: lump disappears, and all the other symptoms remain;
Cure: pain disappears, lump disappears, and simultaneous phenomenon disappears;
Invalid: pain and lump are all not improved.
Through taking pharmaceutical composition of the present invention, the statistical result showed of 200 routine tested patients, treated effect reaches 98%, and cure rate is 83%.
Concrete individual instances is as follows:
1. horse ××, female, 32 years old, Xianyang civil servant.First visit: on August 21st, 2012
Main suit: two newborn pain March.
History of present illness: pain is many to be occurred after depressed, tired, increases the weight of for premenstrual 10 days, mostly is acupuncture sample pain, receive can, dormancy can, two just adjust, because tired, depression are brought out and increased the weight of nearly several months over, menstrual blood volume normally, lmp:8.15.
Have a medical check-up: tongue body is slightly fat, and body of the tongue is light red, no fur, thready and moderate pulse.Training checks: spirit can, after menstruation 6 days, two breast was symmetrical, nipple-areola not and abnormal, left breast outside upper can and 2*2cm, on nipple can and 2*2cm lamellar enclosed mass, tenderness is not obvious, and right breast is not and enclosed mass.
Diagnosis: nodules of the breast (cyclomastopathy)
Dialectical: depression of liver-QI
Control suitable: depressed liver-energy dispersing and QI regulating
Treatment: the electuary that pharmaceutical composition of the present invention is made, takes after mixing it with water for 1 bag, 3 times/day.
Through taking medicine of the present invention, to take after 15 days symptom and take a turn for the better, mastalgia disappears substantially, breast mass comparatively before obviously reduce deliquescing.Exhort that patient takes this medicine in menstruation the last week, continue to strengthen curative effect.Rear patient contacts two menstrual cycle, and more not repeatedly, two newborn enclosed mass does not touch two newborn pain.
2. king's ××, female, 35 years old, Suzhou City resident.First visit: on July 24th, 2012
Main suit: two newborn pain more than 6 years
History of present illness: afterwards angry and premenstrual pain increases the weight of.Mostly be distending pain, receive food can, two just adjust, and sleep not good enough, dreaminess.Once take " Toremifene Citrate sheet ", " RUKANG PIAN " " Rupisanjie capsule " in locality, take the first medicine effective.Menstrual period are normal, amount can, last menstrual period July 13, menstruation has clot, darkish complexion.
Have a medical check-up: light red tongue, tender, indentation is light, few tongue, thready and moderate pulse.
Training checks: after menstruation 11 days, spirit can, two breast is symmetrical, bag-shaped breast, under two nipple can and tortuous glandular tube, left breast outside upper can and 3*3cm tufted thicken body of gland, right breast outside upper can and 2.5*2.5cm thicken body of gland.
Lab testing: the 2013.3.1 Suzhou hospital of traditional Chinese hospital, has the small-sized cystic of mammary gland, two cyclomastopathy.
Diagnosis: nodules of the breast (cyclomastopathy)
Dialectical: stagnation of liver-QI
The rule for the treatment of: depressed liver-energy dispersing and QI regulating
Treatment: the electuary that pharmaceutical composition of the present invention is made, takes after mixing it with water for 1.5 bags, 3 times/day.
2013-7-27 bis-examines
After importing treatment and oral medicine of the present invention through four times, conscious lump deliquescing, haves a medical check-up: the obvious deliquescing of two swelling of the breast blocks is reduced, and takes effect, continual cure.
2013-7-31 tri-examines
Import treatment and take the deliquescing of invention medicine self-induction lump for 7 times, the non-pain of two breast, spirit can.The light red no fur of body of the tongue, stringy pulse delays.The obvious deliquescing of two swelling of the breast blocks is reduced, and in flake, without tenderness, advises the electuary convention amount after treatment menstrual cycle continuing and make with pharmaceutical composition of the present invention.
The 2013-5-17 four diagnostic methods
This year checks.In last treatment rear udder attachment pain, start two mastalgia January in this year, nearly breast in January pain, diet can, poor sleep, two just can.Last menstrual period May 1.Amount is many, 13 days menstrual period.Two breast outside upper can and tortuous glandular tube, without tenderness.
Treatment: Chinese medicine;
Radix Bupleuri 10g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba 15g, Pericarpium Citri Reticulatae Viride 9g, Rhizoma Cyperi 10g, Sargassum 10g, Rhizoma Corydalis 12g, Rhizoma Curcumae 10g.Third Mate is decocted in water for oral dose, 1 dose/day.
2013-5-21 five examines
After medication treatment, self-induction pain obviously alleviates.Existing premenstrual 10 days.Flu, coughs with a small amount of yellow sticky expectorant.Have a medical check-up: receive can, sleep not good enough, difficulty falling asleep.The light red few tongue of body of the tongue.Wiry and frequent pulse.
Treatment: 1, SUNJU GANMAO PIAN; 2, the electuary made of pharmaceutical composition of the present invention, within premenstrual 10 days, take, instructions of taking is the same.
3. Song's ××, female, 49 years old, Langfang in Hebei Province.First visit: on August 13rd, 2013
Main suit: two newborn pain 15 years
History of present illness: how to increase the weight of at premenstrual 15 days, distending pain, diet can, sleep, two just, easily nervous, postponed menstruation 5 days, last menstrual period 7.20, existing premenstrual 5 days,
Look into: complexion is slightly yellow, light red tongue HongShaoJin(SIC), white and thin fur, wiry and frequent pulse,
Training checks: two breast is symmetrical, and nipple-areola color and luster is without exception, two breast outside upper can and the harder body of gland of 3.5*3.5cm
Diagnosis: nodules of the breast (corpus mamma hypertrophy)
Dialectical: stagnation of QI due to depression of the liver, temper is lost
Control suitable: depressed liver-energy dispersing and QI regulating, removing obstruction for relieving pain
Treatment: Radix Bupleuri 10g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba 15g, Pericarpium Citri Reticulatae Viride 9g, Rhizoma Cyperi 10g, Sargassum 10g, Rhizoma Corydalis 12g, Rhizoma Curcumae 10g.Land is paid and is decocted in water for oral dose, 1 dose/day.
2013-8-16 bis-examines
Existing premenstrual 2 days, the two breast of self-induction pain, look into: the obvious deliquescing of two swelling of the breast blocks, micro-have tenderness, the not red work of body of the tongue, thin fur, treatment: 1, hot towel external application, day once, each half an hour;
2, Chinese medicine:
Radix Bupleuri 10g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba 15g, Pericarpium Citri Reticulatae Viride 9g
Rhizoma Cyperi 10g, Sargassum 10g, Rhizoma Corydalis 12g, Rhizoma Curcumae 10g.Third Mate is decocted in water for oral dose, 1 dose/day.
Take through the last week.
4. a ××, female, 51 years old, Liquan County.First visit: on JIUYUE 13rd, 2013
Main suit: two newborn pain more than 3 years, attaches most importance to left breast.
History of present illness: receive can, two just adjust, dormancy can, time have perspiration, warm, weak, being about to cry due to sadness.Menopause 2 years.
Have a medical check-up: body of the tongue is light red, thready and rapid pulse.
Diagnosis: nodules of the breast (cyclomastopathy)
The rule for the treatment of: depressed liver-energy dispersing and QI regulating, adjusts punching to appoint pain relieving
Treatment: Chinese medicine: Radix Bupleuri 12g, Radix Angelicae Sinensis 15g, Radix Paeoniae Alba 15g, Pericarpium Citri Reticulatae Viride 9g, Rhizoma Cyperi 12g, Sargassum 15g, Rhizoma Corydalis 15g, Rhizoma Curcumae 10g.Third Mate is decocted in water for oral dose, 1 dose/day.
2013-9-17 bis-examines
Through taking 3 pairs of treatments by Chinese herbs, two mastalgia disappears, but left breast still has discomfort.Have a medical check-up: spirit can, pale tongue, thready pulse slightly number, left breast outside upper can and the streak enclosed mass of 1*1cm, without tenderness.
Process: take pharmaceutical composition electuary of the present invention 1 bag, take after mixing it with water, 3 times/day, 3 bags.
5. Liu's ××, female, 48 years old, Xi'an.First visit: on JIUYUE 24th, 2013
Main suit: two mammary swelling more than 10 years of pain
History of present illness: receive can, sleep not good enough, two just adjust, sweating, blurred vision flower, companion nipple itch, without discharge.Do not treat.Menstruation menstrual period are normal, hypomenorrhea, last menstrual period August 29.
Have a medical check-up: pale tongue, yellow and thin fur, stringy,thready and rapid pulse.
Training checks: spirit can, two breast is symmetrical, and nipple-areola color and luster is without exception, nipple without discharge, right breast outside upper can and 8*8cm, in matter, while fill the air, left breast outside upper can and 8*8cm, while fill the air, matter is slightly hard.
Lab testing: Jiao great Yi Fu institute: ultrasonic, the low echo nodules of right mammary gland, hyperplastic nodule may.
2013.8.13
Diagnosis: nodules of the breast (cyclomastopathy)
Dialectical: stagnation of QI due to depression of the liver
Process:
Chinese medicine: Radix Bupleuri 12g Radix Paeoniae Alba 20g Radix Angelicae Sinensis 20g Rhizoma Curcumae 15g
Sargassum 20g Rhizoma Corydalis 12g Rhizoma Cyperi 15g Pericarpium Citri Reticulatae Viride 12g
5 pairs, be decocted in water for oral dose, 1 dose/day.
2013-10-17 bis-examines
Through taking 5 pairs of treatments by Chinese herbs, two mastalgia obviously alleviates, breast mass comparatively before obviously reduce deliquescing.Above following the service 7 doses each menstrual cycle the last week.Be used in conjunction 2 menstrual cycle with consolidate curative effect.
6. wait ××, female, 28 years old, Xining.First visit: on JIUYUE 24th, 2008
Main suit: two mastalgia more than 3 years.
History of present illness: relevant with emotion, after anger, premenstrually to increase the weight of, distending pain, twinge, receive can, dormancy can, two just adjust, and xerostomia happiness drink, once took various patent medicine, time has repeatedly, once in JIUYUE, 2012 row " myomectomy ".
Look into: menstrual phase, color are normal, and amount is many, menstruation 10.2 last time, pale tongue, point is red, and few Tianjin, yellow fur is held concurrently in vain mutually, stringy and thready pulse
Training checks: spirit can, two breast is symmetrical, and nipple-areola color and luster is without exception, left breast outside upper can and the streak enclosed mass of 2*2cm, in matter, light tenderness, right breast outside upper can and streak enclosed mass 3*3cm, axillary lymph knot does not touch.
Diagnosis: nodules of the breast (cyclomastopathy)
Dialectical: stagnation of liver-QI
Control suitable: depressed liver-energy dispersing and QI regulating
Treatment: Chinese medicine: Radix Bupleuri 9g Radix Paeoniae Alba 12g Radix Angelicae Sinensis 12g Rhizoma Curcumae 9g
Sargassum 10g Rhizoma Corydalis 10g Rhizoma Cyperi 9g Pericarpium Citri Reticulatae Viride 9g
5 pairs, be decocted in water for oral dose, 1 dose/day.
In premenstrual 10 days following the services.
After 2009-2-21 bis-examines and takes medicine early stage, mastalgia obviously improves, and within nearly 10 days, comes, two newborn pain repeatedly, last menstrual period January 30, existing premenstrual 10 days, receiving can, dormancy can, constipation, looks into: spirit can, left breast outside upper can and 2*2cm matter in enclosed mass, light tenderness, right breast outside upper can and streak enclosed mass 3*3cm, without tenderness.Treatment:
Chinese medicine: Radix Bupleuri 9g Radix Paeoniae Alba 12g Radix Angelicae Sinensis 12g Rhizoma Curcumae 9g
Sargassum 10g Rhizoma Corydalis 10g Rhizoma Cyperi 9g Pericarpium Citri Reticulatae Viride 9g
5 pairs, be decocted in water for oral dose, 1 dose/day.
The experience summing up decades of the present invention, with depressed liver-energy dispersing and QI regulating, hard masses softening and resolving, medicine for promoting blood circulation and dispelling pain, Chong and Ren Meridians regulating is method, composition " pharmaceutical composition for the treatment of cyclomastopathy " experience prescription, sum up through a large amount of clinical efficacy, recent cure rate is 65%, total effective rate is 95%, in the application of clinic experimentation of example up to a hundred, not finding 1 routine untoward reaction case history, is one of Chinese medicine formula medicine for the treatment of cyclomastopathy (nodules of the breast) ideal at present.
Claims (10)
1. treat a pharmaceutical composition for cyclomastopathy, it is characterized in that, be made up of the crude drug of following mass parts: Radix Bupleuri 5 ~ 15 parts, the Radix Paeoniae Alba 10 ~ 20 parts, Radix Angelicae Sinensis 10 ~ 20 parts, Rhizoma Curcumae 5 ~ 15 parts, Sargassum 10 ~ 20 parts, Rhizoma Corydalis 10 ~ 15 parts, 5 ~ 15 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 5 ~ 20 parts.
2. a kind of pharmaceutical composition for the treatment of cyclomastopathy according to claim 1, it is characterized in that, be made up of the crude drug of following mass parts: Radix Bupleuri 10 ~ 15 parts, the Radix Paeoniae Alba 10 ~ 20 parts, Radix Angelicae Sinensis 10 ~ 20 parts, Rhizoma Curcumae 10 ~ 15 parts, Sargassum 10 ~ 20 parts, Rhizoma Corydalis 10 ~ 15 parts, 9 ~ 15 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 10 ~ 20 parts.
3. a kind of pharmaceutical composition for the treatment of cyclomastopathy according to claim 1, is characterized in that, be made up of the crude drug of following mass parts: Radix Bupleuri 10 parts, the Radix Paeoniae Alba 15 parts, Radix Angelicae Sinensis 15 parts, Rhizoma Curcumae 10 parts, Sargassum 10 parts, Rhizoma Corydalis 12 parts, 9 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 10 parts.
4. a kind of pharmaceutical composition for the treatment of cyclomastopathy according to claim 1, is characterized in that, be made up of the crude drug of following mass parts: Radix Bupleuri 12 parts, the Radix Paeoniae Alba 15 parts, Radix Angelicae Sinensis 15 parts, Rhizoma Curcumae 10 parts, Sargassum 15 parts, Rhizoma Corydalis 15 parts, 9 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 12 parts.
5. a kind of pharmaceutical composition for the treatment of cyclomastopathy according to claim 1, is characterized in that, be made up of the crude drug of following mass parts: Radix Bupleuri 12 parts, the Radix Paeoniae Alba 20 parts, Radix Angelicae Sinensis 20 parts, Rhizoma Curcumae 15 parts, Sargassum 20 parts, Rhizoma Corydalis 10 parts, 12 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 15 parts.
6. a kind of pharmaceutical composition for the treatment of cyclomastopathy according to claim 1, is characterized in that, be made up of the crude drug of following mass parts: Radix Bupleuri 9 parts, the Radix Paeoniae Alba 12 parts, Radix Angelicae Sinensis 12 parts, Rhizoma Curcumae 9 parts, Sargassum 10 parts, Rhizoma Corydalis 12 parts, 9 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 9 parts.
7. a kind of pharmaceutical composition for the treatment of cyclomastopathy according to claim 1, is characterized in that, be made up of the crude drug of following mass parts: Radix Bupleuri 5 parts, the Radix Paeoniae Alba 20 parts, Radix Angelicae Sinensis 20 parts, Rhizoma Curcumae 5 parts, Sargassum 15 parts, Rhizoma Corydalis 10 parts, 5 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Cyperi 5 parts.
8. according to a kind of pharmaceutical composition for the treatment of cyclomastopathy in claim 1 ~ 7 described in any one, it is characterized in that, with described pharmaceutical composition for medicinal ingredient, add adjuvant and make oral formulations.
9. a kind of pharmaceutical composition for the treatment of cyclomastopathy according to claim 8, is characterized in that, described oral formulations is tablet, powder, pill, capsule, granule, electuary or oral liquid.
10. a kind of pharmaceutical composition for the treatment of cyclomastopathy according to claim 8, it is characterized in that, described adjuvant comprises one or more in stabilizing agent, solubilizing agent, lubricant or disintegrating agent.
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| CN105727180A (en) * | 2016-03-15 | 2016-07-06 | 兖矿集团有限公司总医院 | Chinese herbal medicine composition for treating mammary gland hyperplasia and preparation method thereof |
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| CN102641478A (en) * | 2012-05-11 | 2012-08-22 | 西安洲良明康生物医药科技有限公司 | Oral medicament for treating hyperplasia of mammary glands |
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| CN102641478A (en) * | 2012-05-11 | 2012-08-22 | 西安洲良明康生物医药科技有限公司 | Oral medicament for treating hyperplasia of mammary glands |
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| 童彩玲: "中医药治疗乳腺增生病摄要", 《中医药学刊》 * |
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| CN105727180A (en) * | 2016-03-15 | 2016-07-06 | 兖矿集团有限公司总医院 | Chinese herbal medicine composition for treating mammary gland hyperplasia and preparation method thereof |
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