CN105853681A - Yao medicine composition for treating depression and preparation method thereof - Google Patents

Yao medicine composition for treating depression and preparation method thereof Download PDF

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Publication number
CN105853681A
CN105853681A CN201610272193.5A CN201610272193A CN105853681A CN 105853681 A CN105853681 A CN 105853681A CN 201610272193 A CN201610272193 A CN 201610272193A CN 105853681 A CN105853681 A CN 105853681A
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China
Prior art keywords
yao
preparation
parts
treating depression
medicine composition
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CN201610272193.5A
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Chinese (zh)
Inventor
张曼
戴建业
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Guangxi University of Chinese Medicine
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Guangxi University of Chinese Medicine
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Priority to CN201610272193.5A priority Critical patent/CN105853681A/en
Publication of CN105853681A publication Critical patent/CN105853681A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/83Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus

Abstract

The invention discloses a Yao medicine composition for treating depression and a preparation method thereof. The Yao medicine composition is prepared from the following Yao medicine raw materials in parts by weight: 2-40 parts of polygala fallax hemsl, 2-20 parts of litsea pungens, 2-40 parts of acorus gramineus, 2-40 parts of lavender, 2-20 parts of albizia julibrissin and 2-20 parts of lily. The dosage form of the Yao medicine composition is powder or tea bags. The preparation process of the Yao medicine composition for treating depression comprises the steps of: crushing the medicinal raw materials, baking, sterilizing and bagging. Shown by clinical tests, the Yao medicine composition disclosed by the invention has definite and stable curative effects of relieving the depressed liver, promoting the circulation of qi, nourishing yin and soothing the nerves without toxic and side effects, and is a Yao health care medicine for treating depression.

Description

A kind of Yao medicinal composition treating depression and preparation method thereof
Technical field
The invention belongs to national medicine field, be specifically related to a kind of Yao medicinal composition treating depression and preparation method thereof.
Background technology
Depression is a kind of with the notable and lasting low affective disorders as main clinical characteristics of mental state, morbidity is many to be changed closely related with the feelings will such as be worried, disgruntled, its pathological changes mechanism it is critical only that feelings will is not relaxed, zang-fu organs qi movement imbalance and strongly fragrant caused in making gas, blood, expectorant, heat, wet, food.In recent years, precious jade medical science gradually payes attention to the impact for disease of the feelings will and the treatment of Emotional disorder, thus the treatment for depression opens a brand-new thinking and approach.
Precious jade doctor thinks that human body is that " god, essence, gas " " three gas unifications " forms.Wherein " refreshing " is by sky, controls soul and psychology, and precious jade doctor is referred to as " waking up ", and human body is left in people's after death soul the most forever." smart " be subject in ground, keep the growth promoter of the human body and physiology, precious jade doctor to be referred to as " steaming "." gas " be subject in neutralization, keep the properly functioning of vital functions, disturbance of QI is the most sick, and precious jade doctor is referred to as " pump ", " young ", " cylinder ".Wherein the body physiological system of people rely on " " food (five tastes) and sick, long, strong, old, extremely.Soul system then rely on " my god " gas (six gas) and sick, long, strong, old, dead.And further raiser has " soul ", it may be assumed that soul is ill people, sleep state or uncomfortable time, part soul can leave body, if being absorbed by extraneous pathogen, it is impossible to returns body, and body system loses balance with manner system.Depression i.e. comes from this.The present invention is shown by 256 example clinical observation result, and behind the side of taking this medicine, depressive emotion and the symptom of patient are improved substantially, and the clinical efficacy of depression is duplicated by this medicine group with Western medicine, but side effect then obvious difference (P < 0.05).This illustrates that this prescription has a preferable antidepressant curative effect, and safety is high, and its possible mechanism of action is, the whole body in this prescription is warming, must from pot bright, clear, red Chu, ring is bright, public asks, have and improve the effect such as depressive emotion and symptom.It is an object of the invention to provide a kind of Yao medicinal composition treating depression and preparation method thereof, it is possible within a short period of time improves depressive emotion and symptom.
Summary of the invention
The invention provides a kind of Yao medicinal composition treating depression.This pharmaceutical composition uses Yao nationality's herb ingredients with effects such as resisting fatigue, depression, raising brain blood circulation, sexuality, suppression glucose metabolisms, overcomes the deficiencies in the prior art, it is possible to improve depressive emotion and symptom within a short period of time.
1. the present invention is achieved through the following technical solutions:
Its raw material is in parts by weight, composed of the following components: the most warming 2-40 part, must ask 2-20 part from bright 2-20 part, clear pot 2-40 part, red Chu 2-40 part, ring bright 2-20 part, public affairs.
The effect of raw material included by Chinese medicine composition of the present invention:
The most warming, [Chinese medicine name] flowers of Edgeworthia chrysantha Lindl, the Yao nationality also referred to as ", Flos Buddlejae, illiteracy snowflake, Flos edgeworthiae, gold gum bag, knotting flower, dream Flos Farfarae, happiness flower ", property puts down, lightly seasoned, returns liver, kidney channel.There is yin nourishing calm the nerves, improving eyesight, the effect hidden from view of dispelling.Main optic atrohic blindness, cataracta, many tear, nocturnal emission, empty pouring, aphonia.
Must be from bright, [precious jade literary composition] dehjomz ndiangx, [Chinese medicine name] Fructus Litseae, property is pungent;Micro-hardship;Temperature.There is eliminating stagnation of regulating the flow of vital energy;Removing toxic substances and promoting subsidence of swelling;The effect of hemostasis, cures mainly: ulcer sore pain;Acute mastitis;Snake bite and insect sting;Traumatic hemorrhage;Swelling of the feet;Chronic tracheitis.
Clear pot, [precious jade literary composition] cingh bouh, [Chinese medicine name] Rhizoma Acori Graminei sweet in the mouth, light, property is put down, and has heat-clearing and toxic substances removing, expelling wind and removing dampness, promoting the circulation of QI to relieve pain, killing parasites for relieving itching, ascarifuge.Cure mainly cold, fever headache, toothache, laryngopharynx swelling and pain, fullness in the chest stomachache, ascaris stomachache, rheumatic arthralgia, numb limbs and tense tendons, menoxenia, dysmenorrhea, visual deterioration, bromhidrosis, skin pruritus.
Red Chu, [precious jade literary composition] hungh cuv, [Chinese medicine name] Herba Lysimachiae foenum-graeci, have another name called Garden lavender, Rhizoma et radix valerianae, Xin Ganwen, enter lung, lunar, the Yangming Channel of foot, there is cold-dispelling, ward off foul effect.Cure the wound cold, headache due to common cold, distension and fullness of the chest and abdomen, lower profit, seminal emission, nasal obstruction, toothache.
Ring is bright, [precious jade literary composition] wiangh nquene ndiangx, [Chinese medicine name] Flos Albiziae, and nature and flavor are sweet, flat, Shu Yu, regulate the flow of vital energy, calm the nerves, active, nourish blood, YIN nourishing kidney, clear away heart-fire improving eyesight.
Public affairs are asked, [precious jade literary composition] gorngh jiouh, [Chinese medicine name] Flos Lilii viriduli, sweet in the mouth, cold nature.GUIXIN, lung meridian.There is nourishing YIN and moistening the lung, the effect of clearing away heart-fire for tranquillization.For deficiency of YIN chronic cough, sputum mixed with blood, fidgets due to deficiency palpitation with fear, insomnia and dreamful sleep, absentminded.
The preparation method of Chinese medicine composition the most of the present invention, it comprises the steps:
Weighing above-mentioned raw materials medical material the most respectively, carried out coarse pulverization, cross 20 mesh sieves, stirring, to mix homogeneously, carries out drying, sterilizing and sterilization processing;The sealed bundle that mixture after above-mentioned process carries out protection against the tide dresses up powder or teabag.
The dosage form of Chinese medicine composition the most of the present invention, is characterized by powder or teabag.
4. the present invention has following effect:
Have clear and definite resolving depression circulation of qi promoting, yin nourishing is calmed the nerves, moisturize pain relieving, the effect such as tonifying YIN promotes the production of body fluid, kidney invigorating and YANG supporting, promoting blood circulation to restore menstrual flow, can play resisting fatigue, depression, raising brain blood circulation, improve depressive emotion and symptom;Yao medicinal composition determined curative effect of the present invention, stable, have no side effect, be a kind of precious jade medicine health care medicinal treating depression.
Detailed description of the invention
Below by embodiment, the invention will be further described, but not as any restriction to scope.
1. composition and the components by weight percent of embodiment 1-3 is shown in Table 1.
2. the EXPERIMENTAL DESIGN of embodiment 1-3 is:
1) select in the first Affiliated Hospital of Guangxi University of Chinese Medicine, depression case 256 example of the attached auspicious health hospital admission of Guangxi University of Chinese Medicine.It is randomly divided into two groups: Yao medicinal composition treatment group 192 example of the present invention, fluoxetine group 64 example.90 Self-reporting inventories (SCL-90), SSRS (SSRS) and the psychosomatic symptom difference of Eysenck Personality Questionnaire (EPQ) (adult) two groups of patients of check and evaluation is used respectively after the treatment of all cases.
2) statistical method: two groups of data compare employing t inspection, χ2Inspection, P < 0.05 has significant for difference.
3. embodiment 1-3 Chinese medicine composition preparation method:
The Yao medicinal composition respective amount of Example 1-3, mixing, coarse pulverization, cross 20 mesh sieves, stirring, to mix homogeneously, carries out drying, sterilizing and sterilization processing;The sealed bundle that mixture after above-mentioned process carries out protection against the tide dresses up powder or teabag.
4. the Therapeutic Method of embodiment 1-3 is:
Yao medicinal composition treatment group totally 192 example of the present invention, Therapeutic Method is: embodiment 1 with 60 grams of net weight, one day three times, divides early, middle and late decocting every time.Embodiment 2 is every time with 80 grams, and one day three times, point early, middle and late direct decocting or boiling water soak 30 minutes, pour out medicinal liquid, work as tea-drinking.Embodiment 3 is every time with 100 grams, one day three times, and point early, middle and late direct decocting or boiling water soak 30 minutes, pour out medicinal liquid, work as tea-drinking.30 days per courses for the treatment of of embodiment 1-3.
Comparison Fluoxetine in Treatment group 64 example: employing Fluoxetine in Treatment, each 20mg, once a day;It within 30 days, it is a course for the treatment of.
Observation index after drug withdrawal 3 days.Prohibit the use of any other medicine during observation, the most do not use other non-drug therapy methods.
5. the result of implementation of embodiment of the present invention 1-3 is shown in Table 2.
Table 1: Yao medicinal composition composition of the present invention and components by weight percent
(n=64, X ± S) is compared in table 2:SCL-90 scoring
Note: compare with matched group, ▲ P < 0.05
(n=64, X ± S) is compared in table 3:SSRS scoring
Note: compare with matched group, ▲ P < 0.05
(n=64, X ± S) is compared in table 4:EPQ assessment
Note: compare with matched group, ▲ P < 0.05
Table 4: untoward reaction rate compares (n=64, X ± S)
Note: compare with matched group, ▲ P < 0.05.

Claims (4)

1. Yao medicinal composition treating depression and preparation method thereof, it is characterised in that be made up of the precious jade medicine raw material of following weight portion: the most warming 2-40 Part, 2-20 part must be asked from bright 2-20 part, clear pot 2-40 part, red Chu 2-40 part, ring bright 2-20 part, public affairs.
2. a kind of Yao medicinal composition treating depression as claimed in claim 1 and preparation method thereof, it is characterised in that: its product forms is scattered Agent or teabag.
3. Yao medicinal composition of a treatment depression as claimed in claim 1 and preparation method thereof, it is characterised in that: by the crude drug of Yao medicinal composition Material carries out coarse pulverization, crosses 20 mesh sieves, and stirring, to mix homogeneously, carries out drying, sterilizing and sterilization processing;Mixture after above-mentioned process is carried out Moistureproof sealed bundle dresses up powder or teabag.
4. Yao medicinal composition of a treatment depression as claimed in claim 1 and preparation method thereof, it is characterised in that: have clear and definite resolving depression circulation of qi promoting, Yin nourishing is calmed the nerves effect, determined curative effect, stable, has no side effect, is a kind of precious jade medicine health care medicinal treating depression.
CN201610272193.5A 2016-04-29 2016-04-29 Yao medicine composition for treating depression and preparation method thereof Pending CN105853681A (en)

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108245641A (en) * 2016-12-28 2018-07-06 广西中医药大学 It is a kind of for oriental paperbush flower precious jade medicine composition of depression and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102600323A (en) * 2012-04-23 2012-07-25 上海中医药大学 Chinese medicinal composition for treating depression, as well as preparation method and application thereof
CN104288677A (en) * 2014-09-26 2015-01-21 广西中医药大学 Yao medicine composition for treating depression and preparation method thereof
CN104383449A (en) * 2014-11-28 2015-03-04 邹士东 Pharmaceutical composition for treating depression syndrome
CN105213867A (en) * 2015-11-10 2016-01-06 夏放军 A kind of Chinese medicine decocting unguentum of calming the nerves and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102600323A (en) * 2012-04-23 2012-07-25 上海中医药大学 Chinese medicinal composition for treating depression, as well as preparation method and application thereof
CN104288677A (en) * 2014-09-26 2015-01-21 广西中医药大学 Yao medicine composition for treating depression and preparation method thereof
CN104383449A (en) * 2014-11-28 2015-03-04 邹士东 Pharmaceutical composition for treating depression syndrome
CN105213867A (en) * 2015-11-10 2016-01-06 夏放军 A kind of Chinese medicine decocting unguentum of calming the nerves and preparation method thereof

Non-Patent Citations (1)

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Title
包祖晓: "《抑郁症诊治心语》", 31 January 2014, 人民军医出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108245641A (en) * 2016-12-28 2018-07-06 广西中医药大学 It is a kind of for oriental paperbush flower precious jade medicine composition of depression and preparation method thereof

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Application publication date: 20160817

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