CN104435585A - 一种治疗痰浊中阻型高脂血症的中药组合物 - Google Patents
一种治疗痰浊中阻型高脂血症的中药组合物 Download PDFInfo
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- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种治疗痰浊中阻型高脂血症的中药组合物，其特征是由下列重量配比的药材制成：化橘红3-6份、法半夏6-9份、赤阳子15-20份、鸡肉丝菇6-9份、蓝锡莎菊12-15份、算盘七6-9份、冷水花15-20份、罗浮柿根9-12份、莎木面3-6份、炙甘草6-9份、罗布麻6-9份、半拉子10-15份、玳玳花1-3份、蒟酱叶10-15份、陈皮6-9份、柳树寄生10-15份、功劳子6-9份。本发明的中药组合物，用于治疗痰浊中阻型高脂血症，有效率高，疗效可靠，愈后不再复发。
Description
技术领域
本发明涉及一种中药，特别是一种用于治疗痰浊中阻型高脂血症的中药组合物。
背景技术
高脂血症属于中医的“痰浊”、“淤血”的范畴。引起高脂血症的主要原因有以下几点：①、饮食因素。恣食肥甘，膏梁厚味，嗜酒无度，损伤脾胃，脾失健运，水谷不化，生痰生湿，痰湿中阻，精微物质输布失司，酿为本病。②、情志因素。长期情志不遂，肝失条达，疏泄失常，气血运行不畅，膏脂布化失度，或思虑过度，伤及脾胃，内生痰湿，可导致本病。③、体质因素。素体肥胖或素体阴虚，也是造成本病原因之一。“肥人多痰湿”，痰浊中阻可致本病。阴虚者多肝肾不足，肝肾阴虚，肝阳偏亢，木旺克土，伤脾胃生痰，或劳欲过度，更伤肾脏，因生命原动力缺乏而致代谢失调，发为本病。其主要症状是脂质在真皮内沉积所引起的黄色瘤和脂质在血管内皮沉积所引起的动脉硬化。目前治疗高脂血症的方法，概括起来主要有以下几种:控制体重、运动锻炼、饮食治疗、血浆净化治疗、外科治疗、西药治疗、中药治疗。这些治疗方法，各有千秋，但中医治疗高脂血症是安全可靠的治疗方式。中医根据不同原因引起的高脂血症，结合临床实际进行辨证治疗，将本病分为：痰浊中阻型、肝郁脾虚型、肝肾亏虚型、气滞血瘀型。
发明内容
本发明的目的旨在提供一种治疗痰浊中阻型高脂血症的中药组合物，通过选择合适的药材及其配比，达到安全有效治愈痰浊中阻型高脂血症的目的。
为达到上述目的，本发明采用以下技术方案：一种治疗痰浊中阻型高脂血症的中药组合物，其特征是由下列重量配比的药材制成：
化橘红3-6份、法半夏6-9份、赤阳子15-20份、鸡肉丝菇6-9份、蓝锡莎菊12-15份、算盘七6-9份、冷水花15-20份、罗浮柿根9-12份、莎木面3-6份、炙甘草6-9份、罗布麻6-9份、半拉子10-15份、玳玳花1-3份、蒟酱叶10-15份、陈皮6-9份、柳树寄生10-15份、功劳子6-9份。
本发明的最佳实施例为在上述配方中再加入倒卵叶五加9-12份、老枪谷根10-15份，以进一步增加健脾的效果。
配方中所涉及到的药材的来源及功能主治如下:
化橘红【来源】药材基源：为芸香科植物化州柚或柚的未成熟或近成熟的外层果皮。【性味】苦；辛；温【归经】脾；肺经【功能主治】燥湿化痰；理气；消食。主风寒咳喘痰多；呕吐呃逆；食积不化；脘腹胀痛。
法半夏【来源】本品为半夏的炮制加工品。【性味】辛、温。【归经】归脾、胃、肺经。【功能主治】燥湿化痰。用于痰多咳喘，痰饮眩悸，风痰眩晕，痰厥头痛。
赤阳子【来源】药材基源：为蔷薇科植物火棘的果实。【性味】甘；酸；涩；平；无毒【归经】肝；脾；胃经【功能主治】健脾消积；收敛止痢；止痛。主痞块；食积停滞；脘腹胀满；泄泻；痢疾；崩漏；带下；跌打损伤。
鸡肉丝菇【来源】药材基源：为白蘑科植物鸡（土从）的子实体。采收和储藏：夏、秋季节采收后除去泥沙，晒干，备用。【性味】甘；性平【归经】脾；胃；大肠经。【功能主治】健脾和胃；疗痔。主脘腹胀满，消化不良，精神疲乏，痔疮。
蓝锡莎菊【来源】药材基源：为菊科植物蓝锡莎菊的根。【性味】味苦；性平【功能主治】健脾和胃。主胃炎；胃；十二指肠溃疡；食欲不振。
算盘七【来源】药材基源：为百合科植物腋花扭柄花的根。【性味】甘；微寒【功能主治】清肺止咳；健脾和胃。主肺热咳嗽；阴虚劳嗽；脾胃不和之少食；欲呕。
冷水花【来源】药材基源：为荨麻科植物冷水花的全草。【性味】淡；微苦；性凉【功能主治】清热利湿；退黄；消肿散结；健脾和胃。主湿热黄疸；赤白带下；淋浊；尿血；小儿夏季热；疟母；消化不良；跌打损伤；外伤感染。
倒卵叶五加【来源】药材基源：为五加科植物倒卵叶五加的根或茎。【性味】味甘；微苦；性温【功能主治】健脾益气；补肾宁心；舒筋活络。主体虚乏力；食欲不振；腰膝酸软；阳痿；失眠多梦；健忘；风寒湿痹。
老枪谷根【来源】药材基源：为苋科植物尾穗苋的根。【性味】甘；性平【归经】脾；肾经【功能主治】健脾；消疳。主脾胃虚弱之倦怠乏力、食少；小儿疳积。
罗浮柿根【来源】药材基源：为柿科植物罗浮柿的根。【性味】微苦；涩；性平【功能主治】健脾利湿。主纳呆；腹泻。
莎木面【来源】为棕榈科植物西谷椰子的木髓部提出的淀粉。【性味】甘，温。【功能主治】温中健脾。治脾胃虚弱，消化不良。
炙甘草【来源】本品为甘草的炮制加工品。【性味】甘，平。【归经】归心、肺、脾、胃经 。【功能主治】补脾和胃，益气复脉。用于脾胃虚弱，倦怠乏力，心动悸，脉结代。
罗布麻【来源】药材基源：为夹竹桃科植物罗布麻的叶。【性味】甘；微苦；性凉【功能主治】清热平肝；利水消肿。主高血压；眩晕；头痛；心悸；失眠。
半拉子【来源】药材基源：为桦木科植物千金榆的果穗。【性味】甘；淡；性平【功能主治】健胃消食。主脾胃虚弱；食欲不振；脘腹胀满；消化不良。
玳玳花【来源】药材基源：为芸香科植物玳玳花的花蕾。【性味】辛；甘；微苦；性平【功能主治】理气宽胸；和胃止呕。主胸中痞闷；脘腹胀痛；不思饮食；恶心呕吐。
蒟酱叶【来源】药材基源：为胡椒科植物蒟酱Piper betle L.的叶。【性味】辛；温【归经】肺；胃经【功能主治】疏风散寒，行气化痰，解毒消肿，燥温止痒。主风寒咳嗽，哮喘，百日咳，院腹胀痛，食滞纳呆，水肿，跌打伤肿，风湿骨痛，疮疡肿毒，痔疮肿痛，汤火伤，风毒脚气，疥癞，湿疹疫痒。
陈皮【来源】本品为芸香科植物橘Citrus reticulata Blanco 及其栽培变种的干燥成熟果皮。【性味】苦、辛，温。【归经】归肺、脾经。【功能主治】理气健脾，燥湿化痰。用于胸脘胀满，食少吐泻，咳嗽痰多。
柳树寄生【来源】药材基源：为桑寄生科植物柳叶钝果寄生的带叶茎枝。【性味】微苦；甘；性平【归经】肝；肾经【功能主治】补肝肾；祛风湿；止血；安胎。主头晕目眩；腰膝疼痛；风湿麻木；崩漏；胎动不安。
功劳子【来源】药材基源：为小檗科植物阔叶十大功Mahonia bealei (Fort.)Carr.细叶十大功劳Mahonia fortunei (Lindl.)fedde等的果实。【性味】苦；凉【归经】脾；肾；膀胱经【功能主治】清虚热；补肾；燥湿。主骨蒸潮热；腰膝酸软；头晕耳鸣；湿热腹泻；带下；淋浊。
在中医辨证治疗的过程中，我们通常结合实验室检查来进一步确诊。中医认为，高脂来源于水谷，其化生、输布、代谢有赖于脏腑功能正常，根本则在于脾胃运化功能、肝、脾、肾三脏虚损。肾为先天之本，肾主水，主津液，具有主持和调节人体津液代谢的作用。肝为刚脏，主疏泄，肝主疏泄功能正常，则气机的运行正常，气血调和，经脉通利。痰浊中阻型高脂血症表现为形体肥胖，心悸眩晕，胸脘痞满，腹胀纳呆，乏力倦怠，恶心吐涎，口渴不欲饮水，舌淡体胖边有齿痕，苔腻，脉濡。治法当以燥湿化痰，健脾和胃。本发明采用科学的配方及配比，配方中所采用的化橘红具有燥湿化痰、理气、消食的功效；法半夏具有燥湿化痰的功效；赤阳子具有健脾消积、收敛止痢、止痛的功效；鸡肉丝菇具有健脾和胃、疗痔的功效；蓝锡莎菊具有健脾和胃的功效；算盘七具有清肺止咳、健脾和胃的功效；冷水花具有清热利湿、退黄、消肿散结、健脾和胃的功效；倒卵叶五加具有健脾益气、补肾宁心、舒筋活络的功效；老枪谷根具有健脾、消疳的功效；罗浮柿根具有健脾利湿的功效；莎木面具有温中健脾的功效；炙甘草具有补脾和胃，益气复脉的功效；罗布麻具有清热平肝、利水消肿的功效；半拉子具有健胃消食的功效；玳玳花具有理气宽胸、和胃止呕的功效；蒟酱叶具有疏风散寒、行气化痰、解毒消肿、燥温止痒的功效；陈皮具有理气健脾、燥湿化痰的功效；柳树寄生具有补肝肾、祛风湿、止血、安胎的功效；功劳子具有清虚热、补肾、燥湿的功效。配方中的各药物之间相互配合，协同作用，所制成的中药具有燥湿化痰、健脾和胃的功效，能有效治疗痰浊中阻型高脂血症，多年来，通过对40例此类患者的跟踪调查统计，有效率达95%，治疗效果好。
具体实施方式
下面结合具体实施的例子对本发明做进一步详细的描述。
实施例1
称取化橘红3克、法半夏6克、赤阳子15克、鸡肉丝菇6克、蓝锡莎菊12克、算盘七6克、冷水花15克、罗浮柿根9克、莎木面3克、炙甘草6克、罗布麻6克、半拉子10克、玳玳花1克、蒟酱叶10克、陈皮6克、柳树寄生10克、功劳子6克、倒卵叶五加9克、老枪谷根10克。将以上各种药材粉磨成末，然后用常规方法“全成分”提取制成速溶中药颗粒，按照每小袋10克进行分装，密闭，于阴凉、干燥处保存。
用于治疗痰浊中阻型高脂血症。口服，每日分早、中、晚三次服用。
具体实施例2
称取化橘红6克、法半夏9克、赤阳子20克、鸡肉丝菇9克、蓝锡莎菊15克、算盘七9克、冷水花20克、罗浮柿根12克、莎木面6克、炙甘草9克、罗布麻9克、半拉子15克、玳玳花3克、蒟酱叶15克、陈皮9克、柳树寄生15克、功劳子9克、倒卵叶五加12克、老枪谷根15克。将以上各种药材粉磨成末，然后用常规方法“全成分”提取制成速溶中药颗粒，按照每小袋10克进行分装，密闭，于阴凉、干燥处保存。
用于治疗痰浊中阻型高脂血症。口服，每日分早、中、晚三次服用。
具体实施例3
称取化橘红5克、法半夏7克、赤阳子16克、鸡肉丝菇8克、蓝锡莎菊13克、算盘七8克、冷水花18克、罗浮柿根10克、莎木面5克、炙甘草8克、罗布麻8克、半拉子12克、玳玳花2克、蒟酱叶11克、陈皮8克、柳树寄生12克、功劳子8克、倒卵叶五加10克、老枪谷根12克。将以上各种药材粉磨成末，然后用常规方法“全成分”提取制成速溶中药颗粒，按照每小袋10克进行分装，密闭，于阴凉、干燥处保存。
用于治疗痰浊中阻型高脂血症。口服，每日分早、中、晚三次服用。
下面结合临床实验数据来说明本发明的有益效果：
1、抽样方法
从近五年来确诊为痰浊中阻型高脂血症的患者中，随机选取80例病人，其中，男46例，女34例，年龄30-80岁。随机分为对照组和治疗组，每组各40人。两组年龄等资料无显著性差异，具有可比性。
2、试验方法
2．1对照组患者使用辛伐他汀片，按说明书服用。
2．2治疗组口服本发明按照具体实施例1制得的中药颗粒，早、中、晚各一次。疗程6周。
3、疗效标准及治疗结果
临床治愈：临床症状、体征消失，实验室各项检查恢复正常。显效：临床症状、体征基本消失，血脂检测达到以下任一项者。 TC下降≥20％， TG下降≥40％， HDL-C上升≥0.26mmol／L （10mg／d1)，TC-HDL-C／HDL-C下降≥20％。有效：血脂检测达到以下任一项者。 TC 下降≥10％但＜20％，TG下降≥20％但＜40％， HDL-C上升≥0.104mmol／L （4mg／dl) 但＜0. 26mmol／L （10mg／dl)， TC-HDL-C／HDL-C下降≥10％但＜20％。 无效：治疗后症状、体征与血脂检测无明显改善者。
3.2治疗统计结果见表1。
表1两组疗效比较
由此可见，采用本发明的组方制得的药物能够安全有效治疗痰浊中阻型高脂血症。
Claims (2)
1.一种治疗痰浊中阻型高脂血症的中药组合物，其特征是由下列重量配比的药材制成：
化橘红3-6份、法半夏6-9份、赤阳子15-20份、鸡肉丝菇6-9份、蓝锡莎菊12-15份、算盘七6-9份、冷水花15-20份、罗浮柿根9-12份、莎木面3-6份、炙甘草6-9份、罗布麻6-9份、半拉子10-15份、玳玳花1-3份、蒟酱叶10-15份、陈皮6-9份、柳树寄生10-15份、功劳子6-9份。
2.按照权利要求1所述的治疗痰浊中阻型高脂血症的中药组合物，其特征是加入倒卵叶五加9-12份、老枪谷根10-15份。
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| CN1440804A (zh) * | 2003-03-31 | 2003-09-10 | 江西汇仁药业有限公司 | 一种降血脂的中药 |
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