CN104435148A - Traditional Chinese medicine for treating chronic gastritis and preparation method of traditional Chinese medicine - Google Patents

Traditional Chinese medicine for treating chronic gastritis and preparation method of traditional Chinese medicine Download PDF

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CN104435148A
CN104435148A CN201410793675.6A CN201410793675A CN104435148A CN 104435148 A CN104435148 A CN 104435148A CN 201410793675 A CN201410793675 A CN 201410793675A CN 104435148 A CN104435148 A CN 104435148A
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chronic gastritis
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孙晓兵
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Abstract

The invention discloses a traditional Chinese medicine for treating chronic gastritis. The traditional Chinese medicine is prepared from the following medicinal materials in parts by weight: 30 parts of fried astragalus membranaceus, 30 parts of wild celery seeds, 20 parts of medical stone, 10 parts of commiphora mukul, 20 parts of radix paeoniae alba, 6 parts of liquorice, 20 parts of sesame flower flour, 10 parts of nagkassar flower, 15 parts of common andrographis herb, 12 parts of blueflower cicerbita root and 10 parts of paleaceous knotweed rhizome. A clinical experiment proves that the significant efficacy of treating the chronic gastritis is achieved by selecting proper medicine materials at a proper ratio; and the traditional Chinese medicine is safe, and free of a toxic or side effect.

Description

A kind of Chinese medicine being used for the treatment of chronic gastritis and preparation method thereof
Technical field
the present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of chronic gastritis and preparation method thereof.
Background technology
chronic gastritis is the invasion and attack repeatedly that gastric epithelial suffers various virulence factor, and persistence chronic inflammation pathological changes occurs.The factors such as its morbidity and unhappy, eating and drinking without temperance (as be addicted to drink, irregular eating, eating cold and uncooked food excessively are pungent) and gastritis Helicobacter pylori infection are relevant.Clinical symptoms has middle epigastrium pain or full vexed sense, pain or lead and breast side of body back, loss of appetite, acid regurgitation water, nausea and vomiting, belch etc., with the passing of time then there is scorching hot, dull pain, have hunger sensation and can not eat, eat rear glutted, the symptom such as complexion is turned white, become thin, anemia in recurrent exerbation.The effective medicine of generally recognized as safe is still lacked at present for chronic gastritis.
Summary of the invention
the present invention aims to provide a kind of Chinese medicine being used for the treatment of chronic gastritis and preparation method thereof, by selecting suitable medical material and proportioning thereof, reaches the remarkable efficacy contributing to Patients with Chronic Gastritis rehabilitation, and safe without toxic side effect.
in order to achieve the above object, the present invention is by the following technical solutions: a kind of Chinese medicine being used for the treatment of chronic gastritis, is prepared from by the medical material of following weight proportion: parching to brown stilbene 25 ~ 30 parts, smallage 25 ~ 30 parts, 15 ~ 20 parts, refining mountain stone, Commiphora mukul 8 ~ 10 parts, the Radix Paeoniae Alba 15 ~ 20 parts, 4 ~ 6 parts, Radix Glycyrrhizae, Semen Sesami pollen 15 ~ 20 parts, ferreous mesua spend 8 ~ 10 parts, Herba Andrographis 12 ~ 15 parts, Cicerbita cyanea (D. Don) beauverd 0 ~ 12 part, Rhizoma Polygoni Paleachi 0 ~ 10 part.
as preferably, be prepared from by the medical material of following weight proportion: parching to brown stilbene 30 parts, smallage 30 parts, 20 parts, refining mountain stone, Commiphora mukul 10 parts, the Radix Paeoniae Alba 20 parts, 6 parts, Radix Glycyrrhizae, Semen Sesami pollen 20 parts, ferreous mesua spend 10 parts, Herba Andrographis 15 parts.
as preferably, be prepared from by the medical material of following weight proportion: parching to brown stilbene 30 parts, smallage 30 parts, 20 parts, refining mountain stone, Commiphora mukul 10 parts, the Radix Paeoniae Alba 20 parts, 6 parts, Radix Glycyrrhizae, Semen Sesami pollen 20 parts, ferreous mesua spend 10 parts, Herba Andrographis 15 parts, Rhizoma Polygoni Paleachi 10 parts.
as preferably, be prepared from by the medical material of following weight proportion: parching to brown stilbene 30 parts, smallage 30 parts, 20 parts, refining mountain stone, Commiphora mukul 10 parts, the Radix Paeoniae Alba 20 parts, 6 parts, Radix Glycyrrhizae, Semen Sesami pollen 20 parts, ferreous mesua spend 10 parts, Herba Andrographis 15 parts, Cicerbita cyanea (D. Don) beauverd 12 parts.
as preferably, be prepared from by the medical material of following weight proportion: parching to brown stilbene 30 parts, smallage 30 parts, 20 parts, refining mountain stone, Commiphora mukul 10 parts, the Radix Paeoniae Alba 20 parts, 6 parts, Radix Glycyrrhizae, Semen Sesami pollen 20 parts, ferreous mesua spend 10 parts, Herba Andrographis 15 parts, Cicerbita cyanea (D. Don) beauverd 12 parts, Rhizoma Polygoni Paleachi 10 parts.
a kind of preparation method being used for the treatment of the Chinese medicine of chronic gastritis, comprise the steps: that parching to brown stilbene, smallage, the Radix Paeoniae Alba, Radix Glycyrrhizae, ferreous mesua spend by (1), Herba Andrographis, Cicerbita cyanea (D. Don) beauverd, Rhizoma Polygoni Paleachi put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) refining mountain stone, Commiphora mukul pulverization are mixed with Semen Sesami pollen and put into container, add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain Chinese medicine preparation of the present invention.
the pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
parching to brown stilbene [nature and flavor] is sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
the dry mature fruit that smallage [source] is samphire smallage.[nature and flavor] three grades are xeothermic, bitter in the mouth.[function cures mainly] raw dry heat-dissipating, cold relieving diuresis, loose gas pain relieving, dampness is whetted the appetite, and stimulates the menstrual flow in warm palace.Cure mainly raw property or lymphatic temperament disease, as cold dysuria, depressed property stomachache, abdominal distention, hypochondriac pain, moist dyspepsia, anorexia, irregular menstruation etc.
refining mountain stone [source] medical material Ji Yuan: be Acid-intermediate igneous rock rocks beschtauite.[nature and flavor] are sweet; Temperature; Nontoxic.[return through] liver; Stomach; Kidney channel.[function cures mainly] detoxicating and resolving stagnation of pathogens; Removing the necrotic tissue and promoting granulation; Except cold damp eliminating; The liver benefiting stomach invigorating; Blood circulation promoting and blood stasis dispelling; Diuresis fossil; Life lengthening.Main carbuncle carbuncle on the back; Acne; Eczema; Foot gas; Miliaria; Finger is chapped; Chloasma; Toothache; Oral ulcer; Rheumatic arthralgia; Lumbago and backache; Chronic hepatitis; Gastritis; Dysentery; Diabetes; Neurasthenia; Wound is red and swollen; Hypertension; Senile sclerosis of blood vessels; Tumor; Lithangiuria.
the resin that Commiphora mukul [source] is set for olive subject plant Commiphora mukul.[nature and flavor] secondary is dry, three grades of heat, lightly seasoned.[function cures mainly] raw dry heat-dissipating, softening hardness and disperse swelling, strong muscle supports flesh, loosening bowel to relieve constipation, relieving cough and resolving phlegm, anti-inflammatory analgetic.Cure mainly raw property or kill liquid matter disease, as hemorrhoid swelling, the tuberculosis of cervical lymph nodes, paralysis, facial paralysis, limb are quivered disease, and stool is smooth, cough, abundant expectoration, Minor articulus pain, sciatica etc.
the Radix Paeoniae Alba [source] this product is the dry root of ranunculaceae plant Radix Paeoniae.[nature and flavor] are bitter, sour, are slightly cold.[return through] returns liver, spleen channel.The pain relieving of [function cures mainly] suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
radix Glycyrrhizae [nature and flavor] is sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
ferreous mesua spends [source] is the flower of Garcinia maingayii ferreous mesua.[nature and flavor] secondary is xeothermic, bitter in the mouth.[function cures mainly] raw dry heat-dissipating, temperature compensation heart, the refreshing heart pleases will, warm-up tonifying YANG, and dampness mends stomach, and antidiarrheal, holds back wound, the hemorrhoid that disappear of stopping blooding.Cure mainly raw property or lymphatic temperament disease, have a guilty conscience as cold, depression, neurasthenia, coldness of the body YANG excess, moist insufficiency of stomach, diarrhoea and various wet wound, bleeding hemorrhoids etc.[each discussion] " note doctor allusion quotation ": " distribute exotic matter, hot tonifying liver and stomach.”
herba Andrographis [source] this product is the dry aerial parts of acanthaceous plant Herba Andrographis.Tap when stem and leaf is luxuriant at the beginning of autumn, dry.[nature and flavor] are bitter, cold.[return through] GUIXIN, lung, large intestine, urinary bladder channel.[function cures mainly] heat-clearing and toxic substances removing, removing heat from blood, detumescence.For cold, fever, laryngopharynx swelling and pain, aphtha of the mouth and tongue, pertussis chronic cough, dysentery, the puckery pain of pyretic stranguria, carbuncle skin infection, venom.
cicerbita cyanea (D. Don) beauverd [source] Compositae stannum Sha Dendranthema Cicerbita cyanea (D. Don) beauverd, is used as medicine with root.Autumn and winter gather, and clean section is dried.[function cures mainly] benefiting stomach and stopping pain.For gastritis, taste-blindness rate, inappetence.
rhizoma Polygoni Paleachi [source] Polygonaceae arsesmart red shank knotweed, is used as medicine with root stock.Autumn excavates root stock, removes stem and leaf fibrous root, dries.[nature and flavor] are bitter, puckery, tepor.[function cures mainly] promoting blood circulation to remove blood stasis, pain relieving, hemostasis.For chronic gastritis, taste-blindness rate, dysentery, enteritis, menoxenia, redly collapses, leucorrhea, traumatic injury; Wound hemorrhage is controlled in external.
the present invention compared with prior art, has following beneficial effect:
1, Chinese medicine preparation of the present invention for treatment chronic gastritis cure rate high and safe without toxic side effect, and can related complication be prevented.Between formula medical material, compatibility is rigorous, the synergistic function produced after not only making full use of compatibility of drugs, and avoid pharmaceutically-active mutual Hangzhoupro short of money and offset or slacken original effect, more note selecting the compatibility of drugs application that can alleviate or eliminate the strong of medicine or toxic and side effects, firmly avoid the mutual compatibility of medicine and produce toxic reaction or strong side effect.By scientific compatibility, not only complicated in the state of an illness, when fast changing, the present invention can not only effectively organize and implement reasonable treatment, make it reach medicine to remove to disease, and for prevent disease progress, in invade internal organs also have good preventive effect, very valuable on clinical application.
, Chinese medicine preparation of the present invention selects high-quality Chinese crude drug to make, selected medical material compatibility is suitable, meets Chinese medicine and modern medicine study is theoretical, and utilize modern medicine pharmaceutical technology to make, safe without toxic side effect, reach the object for the treatment of both the principal and secondary aspects of a disease, clinic is applied.
Detailed description of the invention
in order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
embodiment 1
take: parching to brown stilbene 30 grams, smallage 30 grams, 20 grams, refining mountain stone, Commiphora mukul 10 grams, the Radix Paeoniae Alba 20 grams, 6 grams, Radix Glycyrrhizae, Semen Sesami pollen 20 grams, ferreous mesua spend 10 grams, Herba Andrographis 15 grams, Cicerbita cyanea (D. Don) beauverd 12 grams, Rhizoma Polygoni Paleachi 10 grams.As follows: parching to brown stilbene, smallage, the Radix Paeoniae Alba, Radix Glycyrrhizae, ferreous mesua spend by (1), Herba Andrographis, Cicerbita cyanea (D. Don) beauverd, Rhizoma Polygoni Paleachi put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) refining mountain stone, Commiphora mukul pulverization are mixed with Semen Sesami pollen and put into container, add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain Chinese medicine preparation of the present invention.
usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal.
embodiment 2
take: parching to brown stilbene 30 grams, smallage 30 grams, 20 grams, refining mountain stone, Commiphora mukul 10 grams, the Radix Paeoniae Alba 20 grams, 6 grams, Radix Glycyrrhizae, Semen Sesami pollen 20 grams, ferreous mesua spend 10 grams, Herba Andrographis 15 grams, Cicerbita cyanea (D. Don) beauverd 12 grams, Rhizoma Polygoni Paleachi 10 grams.
preparation method, the usage and dosage of the present embodiment are identical with embodiment 1.
embodiment 3
take: parching to brown stilbene 30 grams, smallage 30 grams, 20 grams, refining mountain stone, Commiphora mukul 10 grams, the Radix Paeoniae Alba 20 grams, 6 grams, Radix Glycyrrhizae, Semen Sesami pollen 20 grams, ferreous mesua spend 10 grams, Herba Andrographis 15 grams, Cicerbita cyanea (D. Don) beauverd 12 grams, Rhizoma Polygoni Paleachi 10 grams.
preparation method, the usage and dosage of the present embodiment are identical with embodiment 1.
clinical data:
1, case selection:
selected the routine clinical observation of Patients with Chronic Gastritis 58 in my institute's diagnosis and treatment since 2013, clinical symptoms all meets chronic gastritis diagnosis and treatment standard.Patient is divided into treatment group and matched group two groups at random, treatment group 29 example, matched group 29 example.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
, medicament selection:
treatment group takes the Chinese medicinal capsule preparation obtained by the embodiment of the present invention 1, oral, every day 2 times, each 1 time sooner or later, each 1, warm water delivery service after meal; Within 15 days, be 1 course for the treatment of, take 2 courses for the treatment of continuously.
matched group Aomei draws 20mg, every day 1 time; Amoxicillin 0.5g, every day 3 times; Furazolidone 0.1g, every day 3 times; Serve on 14d.Continue and take dioctahedral smectite 6g, every day 3 times; Fourth beautiful jade 5mg, every day 3 times; Serve on 16d.30 days courses for the treatment of.
contrast two groups of curative effects.
, efficacy determination:
(1) cure: clinical symptom disappearance, gastroscope or x-ray check gastric mucosa recover normal.
(2) take a turn for the better: clinical symptoms partial disappearance or obviously alleviate, gastroscope or x-ray check gastric mucosa comparatively before obviously improve.
(3) do not heal: clinical symptoms without improvement gastroscope or x-ray check without take a turn for the better.
, result:
select in the treatment group of the embodiment of the present invention 1 Chinese medicinal capsule, cure 21 examples, take a turn for the better 7 examples, and do not heal 1 example, cure rate 72.4%, total effective rate 96.5%.Laggard line trace in 6 months is followed up a case by regular visits to, all without recurrence.
cure 15 examples in matched group, take a turn for the better 11 examples, and do not heal 3 examples, cure rate 51.7%, total effective rate 89.6%.Laggard line trace in 6 months is followed up a case by regular visits to, and has 1 example recurrence.
above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here cannot give exhaustive to all embodiments.Every belong to technical scheme of the present invention the apparent change of extending out or variation be still in the row of protection scope of the present invention.

Claims (6)

1. one kind is used for the treatment of the Chinese medicine of chronic gastritis, it is characterized in that, be prepared from by the medical material of following weight proportion: parching to brown stilbene 25 ~ 30 parts, smallage 25 ~ 30 parts, 15 ~ 20 parts, refining mountain stone, Commiphora mukul 8 ~ 10 parts, the Radix Paeoniae Alba 15 ~ 20 parts, 4 ~ 6 parts, Radix Glycyrrhizae, Semen Sesami pollen 15 ~ 20 parts, ferreous mesua spend 8 ~ 10 parts, Herba Andrographis 12 ~ 15 parts, Cicerbita cyanea (D. Don) beauverd 0 ~ 12 part, Rhizoma Polygoni Paleachi 0 ~ 10 part.
2. a kind of Chinese medicine being used for the treatment of chronic gastritis according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: parching to brown stilbene 30 parts, smallage 30 parts, 20 parts, refining mountain stone, Commiphora mukul 10 parts, the Radix Paeoniae Alba 20 parts, 6 parts, Radix Glycyrrhizae, Semen Sesami pollen 20 parts, ferreous mesua spend 10 parts, Herba Andrographis 15 parts.
3. a kind of Chinese medicine being used for the treatment of chronic gastritis according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: parching to brown stilbene 30 parts, smallage 30 parts, 20 parts, refining mountain stone, Commiphora mukul 10 parts, the Radix Paeoniae Alba 20 parts, 6 parts, Radix Glycyrrhizae, Semen Sesami pollen 20 parts, ferreous mesua spend 10 parts, Herba Andrographis 15 parts, Rhizoma Polygoni Paleachi 10 parts.
4. a kind of Chinese medicine being used for the treatment of chronic gastritis according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: parching to brown stilbene 30 parts, smallage 30 parts, 20 parts, refining mountain stone, Commiphora mukul 10 parts, the Radix Paeoniae Alba 20 parts, 6 parts, Radix Glycyrrhizae, Semen Sesami pollen 20 parts, ferreous mesua spend 10 parts, Herba Andrographis 15 parts, Cicerbita cyanea (D. Don) beauverd 12 parts.
5. a kind of Chinese medicine being used for the treatment of chronic gastritis according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: parching to brown stilbene 30 parts, smallage 30 parts, 20 parts, refining mountain stone, Commiphora mukul 10 parts, the Radix Paeoniae Alba 20 parts, 6 parts, Radix Glycyrrhizae, Semen Sesami pollen 20 parts, ferreous mesua spend 10 parts, Herba Andrographis 15 parts, Cicerbita cyanea (D. Don) beauverd 12 parts, Rhizoma Polygoni Paleachi 10 parts.
6. one kind is used for the treatment of the preparation method of the Chinese medicine of chronic gastritis, it is characterized in that, comprise the steps: that parching to brown stilbene, smallage, the Radix Paeoniae Alba, Radix Glycyrrhizae, ferreous mesua spend by (1), Herba Andrographis, Cicerbita cyanea (D. Don) beauverd, Rhizoma Polygoni Paleachi put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) refining mountain stone, Commiphora mukul pulverization are mixed with Semen Sesami pollen and put into container, add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain Chinese medicine preparation of the present invention.
CN201410793675.6A 2014-12-20 2014-12-20 Traditional Chinese medicine for treating chronic gastritis and preparation method of traditional Chinese medicine Pending CN104435148A (en)

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