CN104415302A - Traditional Chinese medicine composition for treating rhinitis and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating rhinitis and preparation method thereof Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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Abstract
The invention relates to a traditional Chinese medicine composition for treating rhinitis and a preparation method thereof. The traditional Chinese medicine composition is a medicament which is prepared from fresh ginger, almond and poria cocos, wherein the medicament can be prepared with addition of orange peels, rhizoma alismatis and perilla leaves for treating the rhinitis with nasal obstruction; or can be prepared with addition of orange peels, rhizoma pinellinae praeparata, radix scrophulariae, platycodon grandiflorum and radix glycyrrhizae for treating the rhinitis with clear nasal discharge; or can be prepared with rhizoma pinellinae, radix scrophulariae, platycodon grandiflorum, gypsum and schisandra chinensis for treating the rhinitis with yellow nasal discharge. The medicament is unique in formula, is definite in curative effects, is safe and economical, is free of significant toxic and side effects, has effects of fortifying spleen and dispelling dampness, diffusing lung and freeing orifices, is suitable for rhinitis in nasal obstruction with clear nasal discharge and yellow nasal discharge due to unknown reasons.
Description
One, technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of rhinitis and preparation method thereof, belong to biomedicine field.
Two, background technology
Rhinitis refers to the inflammation of nasal membrane and submucous tissue, and show as hyperemia or edema, patient often there will be nasal obstruction, and stream clear water tears, rhinocnesmus, throat is uncomfortable, the symptoms such as cough.The wash sample material of nasal secretions is called nasal mucus or nasal secretion, and its effect helps dust out, and antibacterial is to keep the health of pulmonary.Under normal circumstances, be drawn to throat after the nasal mucus of mixed cell and dust and finally enter gastric, because its secretory volume is little, generally can not attract much attention.When inflammation appears in intranasal, nasal cavity can secrete a large amount of nasal mucus, and can because of infection yellowing, can cough be caused when flowing through throat, can also flow out through prenaris when nasal mucus amount is very many.Rhinitis divides nose plug type, thin nasal discharge type, yellow thick nasal discharge type three type by cardinal symptom and secretions.
The rhinitis cause of disease roughly divides following three aspects: (1) hologathy, because of long-term chronic disease, as endocrine disturbance, prolonged constipation, nephropathy and cardiovascular disease etc., and causes nasal mucosa for a long time or the repeatly congested or blood stasis of the property sent out.Vitamin deficiency, as vitamin A or C.The antihypertensive drugs such as long-term taking reserpine, can cause nasal cavity vasodilation and produce the symptom like rhinitis.(2) local disease does not thoroughly develop into chronic rhinitis because of: acute rhinitis recurrent exerbation or treatment.Due to contiguous chronic inflammatory disease long-time stimulus or deformity, cause nose and the smooth or drainage obstruction of ventilation occurs, as chronic sinusitis, deviation of nasal septum, chronic tonsillitis or adenoid vegetation etc.(3) environmental factors: having the worker in the environment such as cement, Nicotiana tabacum L., coal dust, flour or chemical substance, nasal mucosa is subject to stimulation and the infringement of the physics and chemistry factor, can cause chronic rhinitis.Humiture environment jumpy, as steel-making, freezing, dry the shop workers such as molten, also more easily there is chronic rhinitis.Chronic rhinitis (comprising chronic simple rhinitis and chronic herpes hypertrophic rhinitis) is common clinical, the cause of disease a lot of and definite due to paathogenic factor is not bright, therefore Modern medical therapy primary disease is based on local symptomatic treatment, there is no desirable etiological treatment medicine.
Chinese herb decoction treats has good curative effect to chronic rhinitis.Chronic rhinitis belongs to " stuffy nose " category of Chinese medicine.Lung opening at nose, lung and then nose key tonneau, have a sharp sense of smell, if insufficiency of lung-QI, Wei Yang is not solid, be then subject to evil poison invasion and attack, lose respectful clearly function, so that evil stagnant nose key, or hungry full overstrain, impairing the spleen and stomach, weakness of the spleen and stomach, transporting is not good for, lose the duty of ascending the clear and descending the turbid, turbid damp is detained nose key, stops up resistance venation, and QI-blood circulation is not smooth and send out as primary disease.Or the people that body is strong, vital QI cannot conquer pathogen, violate nose key during exopathogen, evil poison is stayed for a long time and is not gone, and hinders in venation, and containment QI and blood, so that qi depression to blood stasis, stuffy nose occurs.The morbidity theory of stuffy nose is mainly classified as asthenia of pulmonosplenic qi, the large theory of qi depression to blood stasis two by modern Chinese medicine, the multiplex invigorating the spleen and benefiting QI of method for the treatment of, expelling wind and removing dampness, eliminating evil sensible, blood circulation promoting and blood stasis dispelling etc.
In sum, it is considered herein that rhinitis main pathogenesis hinders key, inhibited pulmonary QI for key with cold-damp, for this reason, found we so that invigorating the spleen for eliminating dampness, lung qi dispersing are sensible for method, Clinical practice is achieved good results.The present invention adopts pure traditional Chinese medicine to form, have determined curative effect, safety, without features such as obvious toxic-side effects.
Three, summary of the invention
The object of the present invention is to provide a kind of determined curative effect, safety, economy, Chinese medicine composition and preparation method thereof without the treatment rhinitis of obvious toxic-side effects, be applicable to the rhinitis of the symptom such as nasal obstruction wake thin nasal discharge, yellow thick nasal discharge that unknown cause causes.
Technical scheme of the present invention: a kind of Chinese medicine composition for the treatment of rhinitis, is characterized in that the medicament be prepared from containing following material composition and weight proportion: 3 ~ 10 parts, Rhizoma Zingiberis Recens, 4 ~ 10 parts, Semen Armeniacae Amarum, 5 ~ 10 parts, Poria.
Treat a Chinese medicine composition for rhinitis as mentioned above, it is characterized in that also adding Pericarpium Citri tangerinae 4 ~ 10 parts, Rhizoma Alismatis 5 ~ 10 parts, Folium Perillae 3 ~ 10 parts, be used for the treatment of nose plug type rhinitis.
Treat a Chinese medicine composition for rhinitis as mentioned above, it is characterized in that also adding Pericarpium Citri tangerinae 3 ~ 10 parts, Rhizoma Pinelliae Preparatum 4 ~ 10 parts, Radix Scrophulariae 5 ~ 10 parts, Radix Platycodonis 3 ~ 10 parts, 4 ~ 10 parts, Radix Glycyrrhizae, be used for the treatment of rhinorrhea with clear discharge type rhinitis.
Treat a Chinese medicine composition for rhinitis as mentioned above, it is characterized in that also adding the Rhizoma Pinelliae 3 ~ 10 parts, Radix Scrophulariae 4 ~ 10 parts, Radix Platycodonis 5 ~ 10 parts, 5 ~ 10 parts, Gypsum Fibrosum, Fructus Schisandrae Chinensis 3 ~ 10 parts, be used for the treatment of nose stream yellow thick nasal discharge type rhinitis.
Treat a preparation method for the Chinese medicine composition of rhinitis, it is characterized in that, by recipe quantity by above each crude drug soak by water 2 ~ 3 times, filter, merging filtrate, makes oral liquid.
Treat a preparation method for the Chinese medicine composition of rhinitis, it is characterized in that finished dosage forms also comprises pill, granule, capsule and tablet.
Time prepared by pill, by recipe quantity, above each crude drug is dried, pulverized, cross 80 ~ 100 mesh sieves, water pill processed is as Semen Raphani size, and dry below 80 DEG C, packaging, to obtain final product.
Time prepared by granule, decocted 2 ~ 3 times by above each starting material with water by recipe quantity, filter, merging filtrate, is evaporated to fluid extract, dry, pulverize, cross 80 ~ 100 mesh sieves, after mixing with 0.3 ~ 0.5% dextrin, be wetting agent with 70 ~ 90% ethanol, make granule, subpackage, to obtain final product.
Time prepared by capsule, decocted 2 ~ 3 times by above each starting material with water by recipe quantity, filter, merging filtrate, is evaporated to fluid extract, dry, pulverize, cross 80 ~ 100 mesh sieves, after mixing with 0.3 ~ 0.5% dextrin, be wetting agent with 70 ~ 90% ethanol, make granule, encapsulated, to obtain final product.
Time prepared by tablet, by recipe quantity, above each starting material with water is decocted 2 ~ 3 times, filter, merging filtrate, is evaporated to fluid extract, dries, pulverize, cross 80 ~ 100 mesh sieves, after mixing with 0.3 ~ 0.5% dextrin, be wetting agent with 70-90% ethanol, make granule, add 0.1 ~ 0.3 magnesium stearate or 0.3 ~ 0.5 differential silica gel, tabletting, subpackage, to obtain final product.
The invention has the advantages that prescription is unique, determined curative effect, safety, economy, without obvious toxic-side effects, there is effect that invigorating the spleen for eliminating dampness, lung qi dispersing are sensible, be applicable to the rhinitis of the symptom such as nasal obstruction wake thin nasal discharge, yellow thick nasal discharge that unknown cause causes.
The routine patients with rhinitis of clinical treatment 90 of the present invention, achieves good results.
1, physical data: 90 routine patients are modern medicine and are diagnosed as rhinitis, wherein male 43 example, women 47 example; 20 ~ 60 years old age, average 40 years old.
2, Therapeutic Method: measure each crude drug soak by water 2 times by prescription, filters, and after mixing, point morning, evening take for twice.It within 7 days, is a course for the treatment of.
3, efficacy assessment standard divides 3 grades: (1) cures: clinical symptoms disappears completely; (2) take a turn for the better: clinical symptom relief; (4) invalid: clinical symptoms is without obvious change.
4, therapeutic outcome: cure 73 examples, account for 81.11%; Take a turn for the better 14 examples, accounts for 15.56%, and invalid 3 examples, account for 3.33%; Total effective rate 96.67%.Obvious toxic-side effects is had no during clinical observation.
Clinical treatment 90 of the present invention routine patients with rhinitis's curative effect situation
Four, detailed description of the invention
With specific embodiment, the present invention is elaborated below:
Embodiment 1:
Raw material is taken: 6 parts, Rhizoma Zingiberis Recens, 7 parts, Semen Armeniacae Amarum, 8 parts, Poria according to following proportioning.
Preparation method: by recipe quantity by above each crude drug soak by water 2 times, filter, merging filtrate, makes oral liquid.
Embodiment 2:
Raw material is taken: 6 parts, Rhizoma Zingiberis Recens, 7 parts, Semen Armeniacae Amarum, 8 parts, Poria, Pericarpium Citri tangerinae 7 parts, Rhizoma Alismatis 8 parts, Folium Perillae 6 parts according to following proportioning.
Preparation method: by recipe quantity by above each crude drug soak by water 2 times, filter, merging filtrate, makes oral liquid.
Embodiment 3:
Raw material is taken: 6 parts, Rhizoma Zingiberis Recens, 7 parts, Semen Armeniacae Amarum, 8 parts, Poria, Pericarpium Citri tangerinae 6 parts, Rhizoma Pinelliae Preparatum 7 parts, Radix Scrophulariae 8 parts, Radix Platycodonis 6 parts, 6 parts, Radix Glycyrrhizae according to following proportioning.
Preparation method: by recipe quantity by above each crude drug soak by water 2 times, filter, merging filtrate, makes oral liquid.
Embodiment 4:
Raw material is taken: 6 parts, Rhizoma Zingiberis Recens, 7 parts, Semen Armeniacae Amarum, 8 parts, Poria, the Rhizoma Pinelliae 6 parts, Radix Scrophulariae 6 parts, Radix Platycodonis 7 parts, 7 parts, Gypsum Fibrosum, Fructus Schisandrae Chinensis 6 parts according to following proportioning.
Preparation method: by recipe quantity by above each crude drug soak by water 2 times, filter, merging filtrate, makes oral liquid.
Embodiment 5:
Raw material is taken: 6 parts, Rhizoma Zingiberis Recens, 7 parts, Semen Armeniacae Amarum, 8 parts, Poria, Pericarpium Citri tangerinae 7 parts, Rhizoma Alismatis 8 parts, Folium Perillae 6 parts according to following proportioning.
Preparation method: prepared by (1) pill: by recipe quantity, above each crude drug is dried, pulverized, cross 100 mesh sieves, water pill processed is as Semen Raphani size, and dry below 80 DEG C, packaging, to obtain final product.(2) granule preparation: decocted 2 ~ 3 times by above each starting material with water by recipe quantity, filter, merging filtrate, is evaporated to fluid extract, dry, pulverize, cross 100 mesh sieves, after mixing with 0.3 ~ 0.5% dextrin, be wetting agent with 70 ~ 90% ethanol, make granule, subpackage, to obtain final product.(3), when prepared by capsule, decocted 2 ~ 3 times by above each starting material with water by recipe quantity, filter, merging filtrate, is evaporated to fluid extract, dry, pulverize, cross 100 mesh sieves, after mixing with 0.3 ~ 0.5% dextrin, be wetting agent with 70 ~ 90% ethanol, make granule, encapsulated, to obtain final product.(4) tablet preparation: by recipe quantity, above each starting material with water is decocted 2 ~ 3 times, filter, merging filtrate, be evaporated to fluid extract, dry, pulverize, cross 80 ~ 100 mesh sieves, after mixing with 0.3 ~ 0.5% dextrin, be wetting agent with 70-90% ethanol, make granule, add 0.1 ~ 0.3 magnesium stearate or 0.3 ~ 0.5 differential silica gel, tabletting, subpackage, to obtain final product.
Embodiment 6:
Raw material is taken: 6 parts, Rhizoma Zingiberis Recens, 7 parts, Semen Armeniacae Amarum, 8 parts, Poria, Pericarpium Citri tangerinae 6 parts, Rhizoma Pinelliae Preparatum 7 parts, Radix Scrophulariae 8 parts, Radix Platycodonis 6 parts, 6 parts, Radix Glycyrrhizae according to following proportioning.
Preparation method: prepared by (1) pill: by recipe quantity, above each crude drug is dried, pulverized, cross 100 mesh sieves, water pill processed is as Semen Raphani size, and dry below 80 DEG C, packaging, to obtain final product.(2) granule preparation: decocted 2 ~ 3 times by above each starting material with water by recipe quantity, filter, merging filtrate, is evaporated to fluid extract, dry, pulverize, cross 100 mesh sieves, after mixing with 0.3 ~ 0.5% dextrin, be wetting agent with 70 ~ 90% ethanol, make granule, subpackage, to obtain final product.(3), when prepared by capsule, decocted 2 ~ 3 times by above each starting material with water by recipe quantity, filter, merging filtrate, is evaporated to fluid extract, dry, pulverize, cross 100 mesh sieves, after mixing with 0.3 ~ 0.5% dextrin, be wetting agent with 70 ~ 90% ethanol, make granule, encapsulated, to obtain final product.(4) tablet preparation: by recipe quantity, above each starting material with water is decocted 2 ~ 3 times, filter, merging filtrate, be evaporated to fluid extract, dry, pulverize, cross 80 ~ 100 mesh sieves, after mixing with 0.3 ~ 0.5% dextrin, be wetting agent with 70-90% ethanol, make granule, add 0.1 ~ 0.3 magnesium stearate or 0.3 ~ 0.5 differential silica gel, tabletting, subpackage, to obtain final product.
Embodiment 7:
Raw material is taken: 6 parts, Rhizoma Zingiberis Recens, 7 parts, Semen Armeniacae Amarum, 8 parts, Poria, the Rhizoma Pinelliae 6 parts, Radix Scrophulariae 6 parts, Radix Platycodonis 7 parts, 7 parts, Gypsum Fibrosum, Fructus Schisandrae Chinensis 6 parts according to following proportioning.
Preparation method: prepared by (1) pill: by recipe quantity, above each crude drug is dried, pulverized, cross 100 mesh sieves, water pill processed is as Semen Raphani size, and dry below 80 DEG C, packaging, to obtain final product.(2) granule preparation: decocted 2 ~ 3 times by above each starting material with water by recipe quantity, filter, merging filtrate, is evaporated to fluid extract, dry, pulverize, cross 100 mesh sieves, after mixing with 0.3 ~ 0.5% dextrin, be wetting agent with 70 ~ 90% ethanol, make granule, subpackage, to obtain final product.(3), when prepared by capsule, decocted 2 ~ 3 times by above each starting material with water by recipe quantity, filter, merging filtrate, is evaporated to fluid extract, dry, pulverize, cross 100 mesh sieves, after mixing with 0.3 ~ 0.5% dextrin, be wetting agent with 70 ~ 90% ethanol, make granule, encapsulated, to obtain final product.(4) tablet preparation: by recipe quantity, above each starting material with water is decocted 2 ~ 3 times, filter, merging filtrate, be evaporated to fluid extract, dry, pulverize, cross 80 ~ 100 mesh sieves, after mixing with 0.3 ~ 0.5% dextrin, be wetting agent with 70-90% ethanol, make granule, add 0.1 ~ 0.3 magnesium stearate or 0.3 ~ 0.5 differential silica gel, tabletting, subpackage, to obtain final product.
Claims (10)
1. treat a Chinese medicine composition for rhinitis, it is characterized in that the medicament be prepared from containing following material composition and weight proportion: 3 ~ 10 parts, Rhizoma Zingiberis Recens, 4 ~ 10 parts, Semen Armeniacae Amarum, 5 ~ 10 parts, Poria.
2. a kind of Chinese medicine composition for the treatment of rhinitis as claimed in claim 1, is characterized in that also adding Pericarpium Citri tangerinae 4 ~ 10 parts, Rhizoma Alismatis 5 ~ 10 parts, Folium Perillae 3 ~ 10 parts.
3. a kind of Chinese medicine composition for the treatment of rhinitis as claimed in claim 1, is characterized in that also adding Pericarpium Citri tangerinae 3 ~ 10 parts, Rhizoma Pinelliae Preparatum 4 ~ 10 parts, Radix Scrophulariae 5 ~ 10 parts, Radix Platycodonis 3 ~ 10 parts, 4 ~ 10 parts, Radix Glycyrrhizae.
4. a kind of Chinese medicine composition for the treatment of rhinitis as claimed in claim 1, is characterized in that also adding the Rhizoma Pinelliae 3 ~ 10 parts, Radix Scrophulariae 4 ~ 10 parts, Radix Platycodonis 5 ~ 10 parts, 5 ~ 10 parts, Gypsum Fibrosum, Fructus Schisandrae Chinensis 3 ~ 10 parts.
5. a kind of Chinese medicine composition for the treatment of rhinitis as described in claim 1,2,3 or 4, it is characterized in that preparation method by recipe quantity by above each crude drug soak by water 2 ~ 3 times, filter, merging filtrate, makes oral liquid.
6. a kind of Chinese medicine composition for the treatment of rhinitis as described in claim 1,2,3 or 4, is characterized in that finished dosage forms also comprises pill, granule, capsule and tablet.
7. pill as claimed in claim 6, when it is characterized in that preparation, dries by recipe quantity above each crude drug, pulverizes, cross 80 ~ 100 mesh sieves, and water pill processed is as Semen Raphani size, and drying below 80 DEG C, packaging, to obtain final product.
8. as claimed in claim 6 granule, when it is characterized in that prepared by agent, by recipe quantity by above each crude drug soak by water 2 ~ 3 times, filter, merging filtrate, is evaporated to fluid extract, dry, pulverize, cross 80 ~ 100 mesh sieves, after mixing with 0.3 ~ 0.5% dextrin, be wetting agent with 70 ~ 90% ethanol, make granule, subpackage, to obtain final product.
9. capsule as claimed in claim 6, when it is characterized in that preparation, by recipe quantity by above each crude drug soak by water 2 ~ 3 times, filter, merging filtrate, is evaporated to fluid extract, dry, pulverize, cross 80 ~ 100 mesh sieves, after mixing with 0.3 ~ 0.5% dextrin, be wetting agent with 70 ~ 90% ethanol, make granule, encapsulated, to obtain final product.
10. tablet as claimed in claim 6, when it is characterized in that preparation, by recipe quantity by above each crude drug soak by water 2 ~ 3 times, filter, merging filtrate, is evaporated to fluid extract, dry, pulverize, cross 80 ~ 100 mesh sieves, after mixing with 0.3 ~ 0.5% dextrin, be wetting agent with 70 ~ 90% ethanol, make granule, add 0.1 ~ 0.3% magnesium stearate or 0.3 ~ 0.5% differential silica gel, tabletting, subpackage, to obtain final product.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105192206A (en) * | 2015-10-29 | 2015-12-30 | 钟茂坚 | Anti-rhinitis teabag |
| CN114042144A (en) * | 2021-11-17 | 2022-02-15 | 山西五台山沙棘制品有限公司 | Platycodon grandiflorum and almond paste and preparation method thereof |
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2013
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Non-Patent Citations (2)
| Title |
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| （清）庆云阁 著，彭静山点校，王春月整理: "《庆云阁医学摘粹》", 30 November 2011, 辽宁科学技术出版社 * |
| 罗大伦 著: "《神医这样看病：罗博士讲古代名医》", 30 April 2009, 吉林文史出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105192206A (en) * | 2015-10-29 | 2015-12-30 | 钟茂坚 | Anti-rhinitis teabag |
| CN114042144A (en) * | 2021-11-17 | 2022-02-15 | 山西五台山沙棘制品有限公司 | Platycodon grandiflorum and almond paste and preparation method thereof |
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