CN104398881A - Traditional Chinese medicinal composition for treating hemorrhoid - Google Patents

Traditional Chinese medicinal composition for treating hemorrhoid Download PDF

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Publication number
CN104398881A
CN104398881A CN201410637082.0A CN201410637082A CN104398881A CN 104398881 A CN104398881 A CN 104398881A CN 201410637082 A CN201410637082 A CN 201410637082A CN 104398881 A CN104398881 A CN 104398881A
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hemorrhoid
traditional chinese
chinese medicinal
medicinal composition
fructus
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CN104398881B (en
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朱志明
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Li Aixiang
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739Sanguisorba (burnet)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/748Oldenlandia or Hedyotis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/17Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
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  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention belongs to the technical field of traditional Chinese medicines and relates to a traditional Chinese medicinal composition for treating hemorrhoid. The traditional Chinese medicinal composition is composed of carbonized sanguisorba root, Oldenlandia diffusa, honey-fried pagodatree pod, fructus forsythiae, cape jasmine and Herba Lopatheri. Through clinical verifications, the traditional Chinese medicinal composition for treating hemorrhoid has high efficiency and is convenient to take. A preparation method of the traditional Chinese medicinal composition is simple. By the use of the traditional Chinese medicinal composition, hemorrhoid is not easy to recur.

Description

A kind of Chinese medicine composition for the treatment of hemorrhoid
Technical field
The invention belongs to tcm field, relate to a kind of Chinese medicine composition for the treatment of hemorrhoid and preparation method thereof.
Background technology
Hemorrhoid, be a kind of common disease being positioned at anus position, any age all can fall ill, but with age, sickness rate increases gradually.In China, hemorrhoid are modal anal and intestinal diseases, have the saying of " ten male nine hemorrhoid ", " ten female ten hemorrhoid ".Cardinal symptom has fecal blood, dyschizia, rectum to fall pain, appearance swollen thing in anus inside is deviate from, flowed out secretions, anus and the hemorrhage pruritis of crissum skin etc.
At present, treatment hemorrhoid have medicine and operation two kinds, but operative therapy relapse rate is high; And postoperative misery is large, recovery time is long.Treatment by Chinese herbs hemorrhoid are to become the first-selection of numerous patient.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of hemorrhoid.
The technical solution used in the present invention is as follows: a kind of Chinese medicine composition for the treatment of hemorrhoid, is characterized in that, be prepared from by following component:
Charred Radix Sanguisorbae, Herba Hedyotidis Diffusae, the sweet Fructus Sophorae, Radix Angelicae Sinensis, Semen Persicae (parched), Fructus Forsythiae, Fructus Gardeniae, Herba Lophatheri.
As preferably, the present invention treats the Chinese medicine composition of hemorrhoid, it is characterized in that, is prepared from by the component of following parts by weight:
Charred Radix Sanguisorbae 40-60, Herba Hedyotidis Diffusae 40-60, sweet Fructus Sophorae 30-40, Radix Angelicae Sinensis 30-40, Semen Persicae 30-40, Fructus Forsythiae 10-20, Fructus Gardeniae 10-20, Herba Lophatheri 10-20.
Chinese medicine composition optimum weight part that preparation the present invention treats hemorrhoid is:
Charred Radix Sanguisorbae 55, Herba Hedyotidis Diffusae 45, the sweet Fructus Sophorae 40, Radix Angelicae Sinensis 35, Semen Persicae 40, Fructus Forsythiae 15, Fructus Gardeniae 20, Herba Lophatheri 20.
The pharmacological action of Chinese medicine of the present invention is as follows:
Charred Radix Sanguisorbae: bitter, sour, puckery, is slightly cold.Enter liver, large intestine channel.Cooling blood for hemostasis, removing toxic substances sore.For having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, burn due to hot liquid or fire, carbuncle sore tumefacting virus.
Herba Hedyotidis Diffusae: sweet, light, cool.Enter stomach, large intestine, small intestine meridian.Heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain.For acute appendicitis (appendicitis), furuncle toxic swelling, jaundice due to damp-heat, the diseases such as dysuria.
The honey Fructus Sophorae: bitter, cold.Return liver, large intestine channel.Clearing away heat-fire, cooling blood for hemostasis.Have blood in stool for intestinal heat, hemorrhoid swell hemorrhage, and liver-heat is had a headache, dizzy conjunctival congestion.
Radix Angelicae Sinensis: sweet, acrid, warm.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
Semen Persicae (parched): bitter, sweet, flat.GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.For amenorrhea, dysmenorrhea , WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.
Fructus Forsythiae: bitter, is slightly cold.Return lung, the heart, small intestine meridian.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.
Fructus Gardeniae: bitter, cold.GUIXIN, lung, tri-jiao channel.Pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, jaundice dark coloured urine, blood strangury and dry pain, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles.
Herba Lophatheri: sweet, light, cold.GUIXIN, stomach, small intestine meridian.Clearing heat and relieving fidgetness, diuresis.For calentura excessive thirst, hot urination drenches pain, aphtha of the mouth and tongue.
The all medicines of we share, and can mutually work in coordination with, attenuation gain, play effect of clearing away heat-fire, removing toxic substances sore, promoting blood circulation and hemostasis altogether, through clinical practice checking, have significant curative effect to hemorrhoid.
The Chinese medicine composition preparation method that the present invention treats hemorrhoid is as follows:
Take each component of above-mentioned weight portion, dry, pulverizing, crosses 80 mesh sieves, after mix homogeneously, loads No. 0 capsule and get final product.
The present invention treats the Chinese medicine composition of hemorrhoid through clinical verification, has effective percentage high, taking convenience, and preparation method is simple, the not easily advantage such as recurrence after healing.
Chinese medicine composition of the present invention year August in August, 2010 to 2014, the routine hemorrhoid patients of clinical observation 136, clinical report is as follows:
1, physical data
136 routine patients all derive from my Out-patient Department, age 18-58 year, 40 years old mean age.The course of disease is many at 30 days to 3 years, average course of disease 1.6 years, comprises external hemorrhoid 55 example, internal hemorrhoid 40 example, mixed hemorrhoid 41 example.
2, diagnostic criteria
Tcm diagnosis standard: " Chinese medical disease Standardization of diagnosis and curative effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues: have anal abscess medical history; Focus has collar extension, pipeline, internal orifice to levy.
Western medicine diagnose standard: 1. intermittence just time podex hemorrhage, showing as stool band blood, dye paper, bleed or penetrate blood; 2., after stool or fatigue, cystic mass is had to deviate from outside anus, can self-resetting or need manual reduction maybe can not reset; 3. podex has foreign body sensation, does not accommodate pain with falling inflation; 4. show color cystic mass on tooth trace, is common in right front, right back, left side, and surface mucous is congested, rotten to the corn or have fibrosis lesion; 5. anal canal and anus edge place mulberry cystic mass, or happen suddenly ecchymosis or thrombosis.
3, exclusion standard
1. other diseases, syndrome or complication.2. associated treatment has been accepted and possibility influential effect observation index.3. with the observation of energy influential effect index, other physiology judged or pathological condition.4. severe cardiac, liver, kidney, hematological affect drug metabolism.5. characterizing population group's (edge design women, psychosis).Before including in, accept Drug therapy, meet inclusive criteria through eluting after date, be not considered as Excluded cases.
4, standard is exited
1. not by the measure of regulation Intervention, curative effect cannot be judged.2. data does not judge curative effect, safety completely without method.3. serious adverse reaction, complication, special physiological change etc., are difficult to continual cure.(untoward reaction person includes bad reflection statistics in).4. the medicine that affects the treatment is used.Exit/come off case and include efficacy determination in by curative effect when exiting/come off.
5, criterion of therapeutical effect
Cure: patient does not occur deviating from or the symptom such as to have blood in stool, nevus core atrophy or disappear completely;
Effective: patient does not occur deviating from or the symptom such as to have blood in stool, and nevus core obviously reduces;
Invalid: symptom is not improved;
Total effective rate=(cure+effectively)/total number of cases × 100%.
6, Therapeutic Method
Prescription: charred Radix Sanguisorbae 55g, Herba Hedyotidis Diffusae 45g, sweet Fructus Sophorae 40g, Radix Angelicae Sinensis 35g, Semen Persicae 40g, Fructus Forsythiae 15g, Fructus Gardeniae 20g, Herba Lophatheri 20g.
Method of preparation and use: said medicine is dry, pulverizing, crosses 80 mesh sieves, after mix homogeneously, loads No. 0 capsule and get final product.Oral, every day 3 times, each 4-8 grain, 7 days was 1 course for the treatment of, serve on 2 courses for the treatment of.
7, therapeutic outcome:
In 136 routine patients, clinical cure 90 example (66.2%), effective 43 examples (31.6%), invalid 3 examples (2.2%), total effective rate is 97.8%.
Model case:
1, Wang, man, 43, suffer from hemorrhoid 1.5 years, cardinal symptom is stool band blood, dye paper, to bleed, be diagnosed as hemorrhoid, cure after using 2 courses for the treatment of of medicine of the present invention, pain, edema, blood stasis disappear completely, stopped bleeding, and stool is normal, follows up a case by regular visits to and does not recur for 1 year.
2, by force certain, female, 54 years old, suffer from hemorrhoid 6 months, cardinal symptom podex has foreign body sensation, does not accommodate pain with falling inflation, stool band blood, dye paper, be diagnosed as hemorrhoid, cure after using 2 courses for the treatment of of medicine of the present invention, pain, edema, blood stasis disappear completely, stopped bleeding, stool is normal, follows up a case by regular visits to and does not recur for 1 year.
3. Lee, man, 40 years old.External hemorrhoid history 3 years, cure after using 2 courses for the treatment of of medicine of the present invention, pain, edema, blood stasis disappear completely, stopped bleeding, and stool is normal, observe 1 year without recurring often with pain, hemorrhage, after edible pungent irritable food more so.
Detailed description of the invention
Below by specific embodiment, the present invention will be described, but the present invention is not limited thereto.
EXAMPLE l
Prescription (weight portion): charred Radix Sanguisorbae 55, Herba Hedyotidis Diffusae 45, the sweet Fructus Sophorae 40, Radix Angelicae Sinensis 35, Semen Persicae 40, Fructus Forsythiae 15, Fructus Gardeniae 20, Herba Lophatheri 20.
Preparation method: each component taking above-mentioned weight portion, dry, pulverizing, crosses 80 mesh sieves, after mix homogeneously, loads No. 0 capsule and get final product.
Embodiment 2
Prescription (weight portion): charred Radix Sanguisorbae 48, Herba Hedyotidis Diffusae 40, the sweet Fructus Sophorae 32, Radix Angelicae Sinensis 32, Semen Persicae 40, Fructus Forsythiae 16, Fructus Gardeniae 10, Herba Lophatheri 15.
Preparation method is with embodiment 1.
Embodiment 3
Prescription (weight portion): charred Radix Sanguisorbae 42, Herba Hedyotidis Diffusae 60, the sweet Fructus Sophorae 30, Radix Angelicae Sinensis 40, Semen Persicae 30, Fructus Forsythiae 14, Fructus Gardeniae 16, Herba Lophatheri 18.
Preparation method is with embodiment 1.

Claims (3)

1. treat a Chinese medicine composition for hemorrhoid, it is characterized in that, be prepared from by following component: charred Radix Sanguisorbae, Herba Hedyotidis Diffusae, the sweet Fructus Sophorae, Radix Angelicae Sinensis, Semen Persicae (parched), Fructus Forsythiae, Fructus Gardeniae, Herba Lophatheri.
2. a kind of Chinese medicine composition for the treatment of hemorrhoid as claimed in claim 1, it is characterized in that, be prepared from by the component of following parts by weight: charred Radix Sanguisorbae 40-60, Herba Hedyotidis Diffusae 40-60, sweet Fructus Sophorae 30-40, Radix Angelicae Sinensis 30-40, Semen Persicae 30-40, Fructus Forsythiae 10-20, Fructus Gardeniae 10-20, Herba Lophatheri 10-20.
3. a kind of Chinese medicine composition for the treatment of hemorrhoid as claimed in claim 1, it is characterized in that, be prepared from by the component of following parts by weight: charred Radix Sanguisorbae 55, Herba Hedyotidis Diffusae 45, the sweet Fructus Sophorae 40, Radix Angelicae Sinensis 35, Semen Persicae 40, Fructus Forsythiae 15, Fructus Gardeniae 20, Herba Lophatheri 20.
CN201410637082.0A 2014-11-13 2014-11-13 A kind of Chinese medicine composition for the treatment of hemorrhoid Expired - Fee Related CN104398881B (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105687825A (en) * 2016-01-29 2016-06-22 林鸿 External preparation for treating hemorrhoids and preparation method
CN106692362A (en) * 2015-08-03 2017-05-24 张立 Traditional Chinese medicine tea-based drink for treating haemorrhoids
CN114224982A (en) * 2022-01-20 2022-03-25 李金龙 Medicine for treating hemorrhoids and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102908523A (en) * 2012-10-30 2013-02-06 宋勇 Traditional Chinese medicine composition for treating haemorrhoids

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102908523A (en) * 2012-10-30 2013-02-06 宋勇 Traditional Chinese medicine composition for treating haemorrhoids

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
中华人民共和国卫生部药典委员会: "《中华人民共和国卫生部药品标准中药成方制剂第一册》", 31 December 1990, article "地榆槐角丸", pages: 65 *
钟希文等: "中医药治疗痔疮的研究概述", 《中医药学刊》, vol. 24, no. 5, 31 May 2006 (2006-05-31), pages 852 - 854 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106692362A (en) * 2015-08-03 2017-05-24 张立 Traditional Chinese medicine tea-based drink for treating haemorrhoids
CN105687825A (en) * 2016-01-29 2016-06-22 林鸿 External preparation for treating hemorrhoids and preparation method
CN114224982A (en) * 2022-01-20 2022-03-25 李金龙 Medicine for treating hemorrhoids and preparation method thereof

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