CN104398824A - Traditional Chinese medicine composition for treating infantile eczema - Google Patents
Traditional Chinese medicine composition for treating infantile eczema Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating infantile eczema and a preparation method thereof and belongs to the field of traditional Chinese medicine. Preferably, the traditional Chinese medicine composition disclosed by the invention is prepared from the following raw material medicines in parts by weight: 15 to 30 parts of dictamni cortex, 10 to 30 parts of saururus chinensis, 30 to 50 parts of radix sophorae flavescentis, 20 to 38 parts of common bletilla tuber, 10 to 20 parts of forsythia suspensa vahl, 5 to 20 parts of isatis root, 5 to 25 parts of Chinese red pepper and 4 to 12 parts of fructus kochiae. The traditional Chinese medicine composition disclosed by the invention can clear heat, promote diuresis, dispel wind and arrest itching, has no irritation to the skin and has no adverse effects and toxic or side effects. Compared with an existing traditional Chinese medicine, the traditional Chinese medicine composition has the advantages of high recovery rate and difficulty in relapse after healing.
Description
Technical field
Medical art of the present invention, relates to a kind of Chinese medicine composition for the treatment of infantile eczema and preparation method thereof.
Background technology
Infantile eczema is a kind of allergic skin disease, is exactly the anaphylaxis dermatosis usually said.Main cause not to tolerate ingestant, inhalation (inhalatio) or contactant or caused by allergy.The child suffering from eczema originally skin rubefaction, occur that erythra, then skin are sent out rough, desquamation, stroke the skin of child as touch is on sand paper.The wet eczema that all can make of heat, chance shows significantly.
Eczema is divided into acute, subacute and chronic three phases by the performance of erythra in its pathogenic process.Onset infringement, for papulovesicle or vesicle appear intensive foxtail millet grain size pimple, in erythema basis, forms rotten to the corn face after vesicle is broken, has serosity to ooze out, incrustation.Acute eczema is dealt with improperly, can transfer subacute or chronic eczema to, can take a turn for the better gradually, but easily recur as suitably treated in time.Can be there is large stretch of erythema in severe one, it is pimple, papulovesicle, vesicle, rotten to the corn sepage in groups, there is thick crust on surface, also can prolong and whole Head And Face or incidence.There is erythematous papules, papulovesicle, vesicle, conscious pruritus in perilesional.Can be there is erosion, incrustation in galling, have pus to ooze out under crust, there is pimple at edge, regional glandular enlargement, tenderness.Neighbouring or remote part also can have parallel line shaped erythema, pimple and the vesicle of scratching caused.
Infantile eczema western medical treatment is mainly divided into external used medicine and endo-medicine, external used medicine mainly contains compound cod-liver oil ointment machin ethacridine zinc oxide cream and coordinates the cream containing 17-hydroxy-11-dehydrocorticosterone, as 1% momestasone furoate, propanoic acid beclometasone emulsifiable paste and Calamine Lotion.Endo-medicine mainly contains corticosteroid hormone, as oral in prednisone etc.
The medicine of Chinese traditional treatment infantile eczema has a lot, but great majority are endo-medicine, and also cause repetitious stimulation to the gastrointestinal of children's while using just, patient father and mother's acceptance is not high, can not extensive use.
Summary of the invention
For overcoming the shortcoming that prior art exists, the present inventor, on the basis of secret prescription handed down in the family from generation to generation, through clinical and experimental study for many years, provides the Chinese medicine composition for the treatment of infantile eczema.
The present invention mainly realizes by the following technical solutions:
Treat a Chinese medicine composition for infantile eczema, it is mainly prepared from by Cortex Dictamni, Rhizoma Saururi (Herba Saururi), Radix Sophorae Flavescentis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Fructus Forsythiae, Radix Isatidis, Pericarpium Zanthoxyli and the Fructus Kochiae.
Preferably, the present invention treats the Chinese medicine composition of infantile eczema, is prepared from by the crude drug of following portions by weight:
Cortex Dictamni 15-30, Rhizoma Saururi (Herba Saururi) 10-30, Radix Sophorae Flavescentis 30-50, Pseudobulbus Bletillae (Rhizoma Bletillae) 20-38, Fructus Forsythiae 10-20, Radix Isatidis 5-20, Pericarpium Zanthoxyli 5-25 and Fructus Kochiae 4-12.
Most preferably, the present invention treats the Chinese medicine composition of infantile eczema, is prepared from by the crude drug of following portions by weight: Cortex Dictamni 20, Rhizoma Saururi (Herba Saururi) 20, Radix Sophorae Flavescentis 40, the Pseudobulbus Bletillae (Rhizoma Bletillae) 28, Fructus Forsythiae 12, Radix Isatidis 8, Pericarpium Zanthoxyli 10 and the Fructus Kochiae 6.
In Chinese medicine composition of the present invention, the pharmacological activity of each crude drug is as follows:
Cortex Dictamni: another name, stereotyped writing cattle, Cortex Argyreiae Seguinii Radicis, the fresh grass of sheep.Source: this product is the dry root bark of rutaceae shaggy-fruited dittany Dictamnusdasycarpus Turcz..Spring, Qiu Erji excavate root, and removing silt and rough bark, strip root bark, dry.Nature and flavor are bitter, cold.Gui Jing, returns spleen, stomach, urinary bladder channel.Function cures mainly, heat clearing and damp drying, removing toxic substances of dispeling the wind.For damp and hot sore, yellow fluid is dripping, eczema, rubella, scabies skin ulcer leprosy, beriberoid pyretic arthralgia, jaundice dark coloured urine.
Rhizoma Saururi (Herba Saururi): source: this product is dry rhizome or the herb of Saururaceae plant Rhizoma Saururi (Herba Saururi) Saururus chinensis (Lour.) Baill..Rhizome is excavated autumn; Herb all can be excavated the whole year, cleans, dries.Nature and flavor, sweet, pungent, cold.Gui Jing, returns lung, urinary bladder channel.Function cures mainly, heat-clearing and toxic substances removing, inducing diuresis to remove edema.For dysuria, drench the puckery pain of drop, leucorrhea, urinary tract infection, oedema due to nephritis; External treatment sore swollen toxin, eczema.
Radix Sophorae Flavescentis: another name, wild Chinese scholartree, Hao Hanzhi, matrine, bone, Chinese scholartree, Albizzia kalkora.Source, this product is the dry root of leguminous plant Radix Sophorae Flavescentis Sophora flavescens Ait..Spring, Qiu Erji excavate, removing root head and little supporting root, cleaning, drying, or take advantage of fresh slices, dry.Nature and flavor are bitter, cold.Gui Jing, GUIXIN, liver, stomach, large intestine, urinary bladder channel.Function cures mainly, heat clearing and damp drying, parasite killing, diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.
The Pseudobulbus Bletillae (Rhizoma Bletillae): another name, Bletilla striata (Thunb.ex A.Murray)Rchb.f., Pseudobulbus Bletillae (Rhizoma Bletillae), Cold boiled chicken, Cold boiled chicken baby, Lian Jicao, YANGJIAOQI.Source, this product is the dry tuber of orchid Pseudobulbus Bletillae (Rhizoma Bletillae) Bletilla striata (Thunb.) Reichb.f..Summer, Qiu Erji excavate, and removing fibrous root, cleans, and put in boiling water and boil or steam to without the white heart, shine to half-dried, removing crust, dries.Nature and flavor, bitter, sweet, puckery, be slightly cold.Gui Jing, returns lung, liver, stomach warp.Function cures mainly, astringing to arrest bleeding, detumescence and promoting granulation.Spit blood for hemoptysis, traumatic hemorrhage, sore swollen toxin, chapped skin; Pulmonary tuberculosis hemoptysis, ulcer haemorrhage.
Fructus Forsythiae: another name, Fructus Forsythiae, Hemerocallis citrina Baroni bar, yellow chain barriness, Huang Qidan, green grass or young crops stick up, fall to sticking up.Source, this product is the dry fruit of Oleaceae plants Fructus Forsythiae Forsythia suspensa (Thunb.) Vahl.Gather during fruit in autumn first ripe still band green, removing impurity, cooks, dries, and practises title " green grass or young crops sticks up "; Gather when fruit is well-done, dry, removing impurity, practises and claims " always sticking up ".Nature and flavor, bitter, be slightly cold.Gui Jing, returns lung, the heart, small intestine meridian.Function cures mainly, heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.
Radix Isatidis: another name, great Lan root, Radix Clerodenri Cyrtophylli.Source, this product is the dry root of cruciferae isatis Isatis indigoticaFort..Autumn excavates, and removing silt, dries.Nature and flavor are bitter, cold.Gui Jing, GUIXIN, stomach warp.Function cures mainly, heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving.For maculae caused by violent heat pathogen, crimson tongue is purple dark, mumps, sore throat, scarlet fever, major part pestilence, erysipelas, carbuncle.
Pericarpium Zanthoxyli: another name, fragrant green pepper, large Pericarpium Zanthoxyli, Semen zanthoxyli.Source, this product is that the dry mature skin (Pericarpium Zanthoxyli) of rutaceae Capsicum annuum L. (fragrant green pepper, Zanthoxylum schinifolium, Pericarpium Zanthoxyli, Canis familiaris L. green pepper) Zanthoxylum schinifolium Sieb.et Zucc. or Pericarpium Zanthoxyli (another name for Sichuan Province green pepper, Fructus Zanthoxyli, Capsicum tetragonum, pericarpium zanthoxyli bungeani, Radix Campylotropis Hirtella (Herba Myrsines Africanae)) Zantho xylum bungeanum Maxim. and seed (Semen zanthoxyli) are used as medicine.To gather autumn mature fruit, remove impurity and dry.Separate for subsequent use with seed.Getting clean Pericarpium Zanthoxyli, according to frying method (appendix II D), frying to there being fragrance.Nature and flavor, pungent, temperature.Gui Jing, returns spleen, stomach, kidney channel.Function cures mainly, warming middle-JIAO to relieve pain, killing parasites for relieving itching.For coldness and pain in the epigastrium, vomiting is had loose bowels, abdominal pain due to worm stagnation, ascariasis; External treatment eczema pruritus.
The Fructus Kochiae: another name, broom Seedling.Source, this product is the dry mature fruit of chenopod Fructus Kochiae Kochia scoparia (L.) Schrad..To gather during fruit maturation in autumn plant, dry, lay fruit, removing impurity.Nature and flavor are pungent, bitter, cold.Gui Jing, returns kidney, urinary bladder channel.Function cures mainly, clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching.For difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus.
The dosage form of the Chinese medicine composition of described treatment infantile eczema is exterior-applied formulation, and described exterior-applied formulation is powder, unguentum, liniment etc.
The preparation method of the Chinese medicine composition exterior-applied formulation of above-mentioned treatment infantile eczema, can be preferably:
1) Cortex Dictamni, Rhizoma Saururi (Herba Saururi), Fructus Forsythiae, Radix Isatidis, Pericarpium Zanthoxyli and the Fructus Kochiae is weighed by weight ratio, add up the water of dose 6 ~ 10 times of weight, soak 0.5 ~ 1 hour, decoct 2 times, each 30 ~ 120min, filters, merging filtrate, concentrated filtrate to volume is 1/6 ~ 1/10 of added water cumulative volume, for subsequent use;
2) get load weighted Radix Sophorae Flavescentis, the Pseudobulbus Bletillae (Rhizoma Bletillae) by weight ratio, pulverize, cross 100 ~ 200 mesh sieves, sterilizing, for subsequent use;
3) take 1) the concentrated solution weight of step 0.2 ~ 0.5% starch, for subsequent use;
4) starch and Lightyellow Sophora Root being mixed, add step 1) in the concentrated solution of gained, stir, adding preservative agent, sterilizing, obtains sterilized solution, and fill in sterilized environment, to obtain final product.
The present invention treats the Chinese medicine composition of infantile eczema can clearing away heat-damp and promoting diuresis, dispelling wind for relieving itching, not chafe, has no adverse reaction and toxic and side effects, compared with existing Chinese medicine, has cure rate high, the advantage not easily recurred after healing.
Clinical data
1 physical data
In JIUYUE, 2012 is routine to the eczema infant 204 of in JIUYUE, 2014 the court outpatient clinic, children age 3 months to 8 years old, the course of disease 2 days to 3 months; All infants are divided into 2 groups at random, treatment group 102 example, man 56 example, women 46 example; Matched group 102 example, male example 56, women 42 example.Two groups of children age, sex, the course of disease, symptoms etc., through statistical analysis not statistically significant, have comparability.
2, Therapeutic Method
Treatment group adopts the embodiment of the present invention 1 medicine to clean affected part, and every day sooner or later respectively once; Matched group adopts Calamine Lotion to smear, twice daily.Continuous treatment 7 days.
3, curative effect determinate standard
1) pruritus degree
0 point: without pruritus, the sleep of infant diet is normal; 1 point of pruritus is light, without crying and screaming; 2 points of rash are itched and are caused agitation, time noisy when crying, do not affect sleep; 3 points of impact sleeps.
2) erythra area
0 point: all disappear without erythra or erythra; 1 point: there is erythra local; 2 points of one-sided limbs are multiple; 3 points: general.
3) erythra form
0 point: all disappear without erythra or erythra; 1 point: erythema; 2 points of papulovesicles or vesicle; 3 points: ooze out or erosion; 4 points: lichenization.
4) curative effect determinate standard
Integration × 100% before therapeutic index (%)=(before treatment the rear integration of integration-treatment)/treatment.
Recovery from illness: therapeutic index >=95%;
Effective: therapeutic index is 65%-94%;
Effective: therapeutic index is 50%-64%;
Invalid: curative effect is less than 50%.
4, statistical method
Application spss16.0 software carries out date processing.Measurement data is used
represent, adopt t inspection, P < 0.05 has statistical significance for difference.
5, therapeutic outcome
Symptom score before and after 5.1 liang of group treatments, see table 1.
Before and after table 1 liang group treatment, symptom score compares
| Group | Number of cases | Symptom score before treatment | Symptom score after treatment |
| Treatment group | 110 | 2.87±0.74 | 0.14±0.05 #* |
| Matched group | 110 | 2.81±0.67 | 0.78±0.10 * |
Remarks: mark compare * P < 0.01 with before treatment; Compare #*P < 0.05 with marking after treatment of control group.
Table 1 is pointed out, the Chinese medicine composition that the present invention treats infantile eczema can improve significantly rapidly pediatric patient symptom, its successful is better than calamine lotion matched group, and treatment group all has significant difference compared with before treatment or compared with the matched group after treatment.
Eczema area and Severity Index (EASI) integration before and after 5.2 liang of group treatments, see table 2.
Before and after table 2 liang group treatment, eczema area and Severity Index compare
| Group | Number of cases | EASI integration before treatment | EASI integration after treatment |
| Treatment group | 110 | 6.89±1.58 | 1.21±0.24#* |
| Matched group | 110 | 6.95±1.64 | 3.58±0.43* |
Remarks: with integral contrast * P < 0.01 before treatment; With integral contrast #*P < 0.05 after treatment of control group.
Table 2 is pointed out, and compares before and after two groups of internal therapies, and after treating, front comparing difference has significance (P < 0.01) with treatment; Compare after treatment between two groups, compare with matched group (P < 0.05), illustrate that treatment group is better than matched group to the improvement that EASI marks.
5.3 liang of group comparitive study, see table 3.
Table 3 liang group comparitive study
| Group | Number of cases | Cure (%) | Effective | Effectively | Invalid | Total effective rate |
| Treatment group | 110 | 80(72.7) | 19 | 9 | 2 | 98.2％ |
| Matched group | 110 | 16(14.5) | 45 | 20 | 29 | 73.6％ |
Table 3 is pointed out, and treatment group cure rate is far away higher than matched group, and effective percentage is also higher than matched group.Visible the present invention treats the Chinese medicine composition of infantile eczema, has the advantage that cure rate is high.
In addition, in therapeutic process, treatment group and matched group all have no obvious adverse reaction.After 3 months, in his-and-hers watches 3, all healing patients pay a return visit, and treatment group successfully pays a return visit 71 people, only 2 example recurrences, and relapse rate is only 2.8%, and matched group successfully pays a return visit 15 people, and recurrence 10 example, relapse rate is about 66.7%.The feature not easily recurred after Chinese medicine of the present invention has healing compared with existing medicine is described.
Detailed description of the invention
The embodiment of the present invention is only in order to illustrate technical scheme of the present invention; be not intended to limit; everyly do not depart from technical solution of the present invention content, any simple modification, equivalent variations and the remodeling done embodiment according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.
EXAMPLE l
Prescription:
Cortex Dictamni 20kg, Rhizoma Saururi (Herba Saururi) 20kg, Radix Sophorae Flavescentis 40kg, Pseudobulbus Bletillae (Rhizoma Bletillae) 28kg, Fructus Forsythiae 12kg, Radix Isatidis 8kg, Pericarpium Zanthoxyli 10kg and Fructus Kochiae 6kg.
Preparation method:
1) weigh Cortex Dictamni, Rhizoma Saururi (Herba Saururi), Fructus Forsythiae, Radix Isatidis, Pericarpium Zanthoxyli and the Fructus Kochiae by weight ratio, add up the water of dose 8 times of weight, soak 1 hour, decoct 2 hours, filter; In filtering residue, add the water of total dose 6 times of weight, decoct 1 hour, filter; Merging filtrate, filtrate is concentrated into volume for 1/7 of added water cumulative volume, for subsequent use;
2) get load weighted Radix Sophorae Flavescentis, the Pseudobulbus Bletillae (Rhizoma Bletillae) by weight ratio, pulverize, cross 200 mesh sieves, sterilizing, for subsequent use;
3) take 1) the concentrated solution weight of step 0.4% starch, for subsequent use;
4) starch and Lightyellow Sophora Root being mixed, add step 1) in the concentrated solution of gained, stir, adding preservative agent, sterilizing, obtains sterilized solution, and fill in sterilized environment, to obtain final product.
Embodiment 2
Prescription:
Cortex Dictamni 17kg, Rhizoma Saururi (Herba Saururi) 25kg, Radix Sophorae Flavescentis 32kg, Pseudobulbus Bletillae (Rhizoma Bletillae) 32kg, Fructus Forsythiae 12kg, Radix Isatidis 16kg, Pericarpium Zanthoxyli 10kg and Fructus Kochiae 8kg.
Preparation method:
1) weigh Cortex Dictamni, Rhizoma Saururi (Herba Saururi), Fructus Forsythiae, Radix Isatidis, Pericarpium Zanthoxyli and the Fructus Kochiae by weight ratio, add up the water of dose 8 times of weight, soak 1 hour, decoct 2 hours, filter; In filtering residue, add the water of total dose 6 times of weight, decoct 1 hour, filter; Merging filtrate, filtrate is concentrated into volume for 1/6 of added water cumulative volume, for subsequent use;
2) get load weighted Radix Sophorae Flavescentis, the Pseudobulbus Bletillae (Rhizoma Bletillae) by weight ratio, pulverize, cross 200 mesh sieves, sterilizing, for subsequent use;
3) take 1) the concentrated solution weight of step 0.4% starch, for subsequent use;
4) starch and Lightyellow Sophora Root being mixed, add step 1) in the concentrated solution of gained, stir, adding preservative agent, sterilizing, obtains sterilized solution, and fill in sterilized environment, to obtain final product.
Embodiment 3
Prescription:
Cortex Dictamni 17kg, Rhizoma Saururi (Herba Saururi) 30kg, Radix Sophorae Flavescentis 50kg, Pseudobulbus Bletillae (Rhizoma Bletillae) 38kg, Fructus Forsythiae 20kg, Radix Isatidis 12kg, Pericarpium Zanthoxyli 18kg and Fructus Kochiae 12kg.
Preparation method:
1) weigh Cortex Dictamni, Rhizoma Saururi (Herba Saururi), Fructus Forsythiae, Radix Isatidis, Pericarpium Zanthoxyli and the Fructus Kochiae by weight ratio, add up the water of dose 10 times of weight, soak 0.5 hour, decoct 2 hours, filter; In filtering residue, add the water of total dose 6 times of weight, decoct 1 hour, filter; Merging filtrate, filtrate is concentrated into volume for 1/8 of added water cumulative volume, for subsequent use;
2) get load weighted Radix Sophorae Flavescentis, the Pseudobulbus Bletillae (Rhizoma Bletillae) by weight ratio, pulverize, cross 200 mesh sieves, sterilizing, for subsequent use;
3) take 1) the concentrated solution weight of step 0.4% starch, for subsequent use;
4) starch and Lightyellow Sophora Root being mixed, add step 1) in the concentrated solution of gained, stir, adding preservative agent, sterilizing, obtains sterilized solution, and fill in sterilized environment, to obtain final product.
Embodiment 4
Prescription:
Cortex Dictamni 15kg, Rhizoma Saururi (Herba Saururi) 15kg, Radix Sophorae Flavescentis 30kg, Pseudobulbus Bletillae (Rhizoma Bletillae) 22kg, Fructus Forsythiae 20kg, Radix Isatidis 20kg, Pericarpium Zanthoxyli 20kg and Fructus Kochiae 10kg.
Preparation method:
1) weigh Cortex Dictamni, Rhizoma Saururi (Herba Saururi), Fructus Forsythiae, Radix Isatidis, Pericarpium Zanthoxyli and the Fructus Kochiae by weight ratio, add up the water of dose 8 times of weight, soak 1 hour, decoct 2 hours, filter; In filtering residue, add the water of total dose 6 times of weight, decoct 1 hour, filter; Merging filtrate, filtrate is concentrated into volume for 1/7 of added water cumulative volume, for subsequent use;
2) get load weighted Radix Sophorae Flavescentis, the Pseudobulbus Bletillae (Rhizoma Bletillae) by weight ratio, pulverize, cross 200 mesh sieves, sterilizing, for subsequent use;
3) take 1) the concentrated solution weight of step 0.4% starch, for subsequent use;
4) starch and Lightyellow Sophora Root being mixed, add step 1) in the concentrated solution of gained, stir, adding preservative agent, sterilizing, obtains sterilized solution, and fill in sterilized environment, to obtain final product.
Claims (4)
1. treat a Chinese medicine composition for infantile eczema, it is characterized in that, it is mainly prepared from by Cortex Dictamni, Rhizoma Saururi (Herba Saururi), Radix Sophorae Flavescentis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Fructus Forsythiae, Radix Isatidis, Pericarpium Zanthoxyli and the Fructus Kochiae.
2. the Chinese medicine composition for the treatment of infantile eczema according to claim 1, it is characterized in that, be prepared from by the crude drug of following portions by weight: Cortex Dictamni 15-30, Rhizoma Saururi (Herba Saururi) 10-30, Radix Sophorae Flavescentis 30-50, Pseudobulbus Bletillae (Rhizoma Bletillae) 20-38, Fructus Forsythiae 10-20, Radix Isatidis 5-20, Pericarpium Zanthoxyli 5-25 and Fructus Kochiae 4-12.
3. the Chinese medicine composition for the treatment of infantile eczema according to claim 1, is characterized in that, is prepared from by the crude drug of following portions by weight: Cortex Dictamni 20, Rhizoma Saururi (Herba Saururi) 20, Radix Sophorae Flavescentis 40, the Pseudobulbus Bletillae (Rhizoma Bletillae) 28, Fructus Forsythiae 12, Radix Isatidis 8, Pericarpium Zanthoxyli 10 and the Fructus Kochiae 6.
4. treat a preparation method for the Chinese medicine composition of infantile eczema, it is characterized in that, comprise following steps:
1) Cortex Dictamni, Rhizoma Saururi (Herba Saururi), Fructus Forsythiae, Radix Isatidis, Pericarpium Zanthoxyli and the Fructus Kochiae is weighed by weight ratio, add up the water of dose 6 ~ 10 times of weight, soak 0.5 ~ 1 hour, decoct 2 times, each 0.5 ~ 2 hour, merging filtrate, filtrate is concentrated into volume for 1/6 ~ 1/10 of added water cumulative volume, for subsequent use;
2) get load weighted Radix Sophorae Flavescentis, the Pseudobulbus Bletillae (Rhizoma Bletillae) by weight ratio, pulverize, cross 100 ~ 200 mesh sieves, sterilizing, for subsequent use;
3) take 1) the concentrated solution weight of step 0.2 ~ 0.5% starch, for subsequent use;
4) starch and Lightyellow Sophora Root being mixed, add step 1) in the concentrated solution of gained, stir, adding preservative agent, sterilizing, obtains sterilized solution, and fill in sterilized environment, to obtain final product.
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| CN103768291A (en) * | 2012-10-22 | 2014-05-07 | 青岛信立德中药技术研究开发有限公司 | External-washing traditional Chinese medicine for treating infantile eczema |
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| "湿疹及皮炎", 《中国医学文摘.皮肤科学》 * |
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| WO2020133948A1 (en) * | 2018-12-25 | 2020-07-02 | 衢州市益年堂农林科技有限公司 | Composition having whitening and anti-oxidation effects and skin care cream thereof |
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