CN104383352A - Chinese medicinal preparation for treating xerophthalmia due to deficiency of yin, dampness and heat - Google Patents
Chinese medicinal preparation for treating xerophthalmia due to deficiency of yin, dampness and heat Download PDFInfo
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Abstract
The invention discloses a Chinese medicinal preparation for treating xerophthalmia due to deficiency of yin, dampness and heat, belonging to the field of traditional Chinese medicines. The Chinese medicinal preparation is prepared from the following Chinese medicinal herbs: atractylodes rhizome, plantain herb, stellaria yunnanensis, eragrostis poaeoides, penthorum chinense pursh, cassia seeds, barbary wolfberry fruits and pale butterflybush flowers. The Chinese medicinal preparation disclosed by the invention has the efficacies of nourishing yin, inducing diuresis, invigorating the spleen, eliminating dampness and regulating the mechanism of qi, is beneficial to effectively increasing the secretion amount of tears and prolonging the breakup time of a tear film and has a significant clinical effect of treating xerophthalmia due to deficiency of yin, dampness and heat.
Description
Technical field
The invention belongs to tcm field, relate to a kind of Chinese medicine preparation for the treatment of deficiency of YIN damp-heat type xerophthalmia particularly.
Background technology
Xerophthalmia refer to due to the exception of tear amount or matter or the abnormal tear film that causes of tear kinetics unstable, the ophthalmic uncomfortables such as go out to lose face dry and astringent, foreign body sensation, furious photophobia, burn feeling, asthenopia and visual deterioration, have the disease of ocular surface injury simultaneously.Research in China to xerophthalmia is carried out more late, so far still planless xerophthalmia Epidemiological study, along with social senilization and office computer, corneal contact lens universal, its sickness rate is in rising trend, severe dry eye patient can cause vision obviously to decline, if corneal injury seriously can cause blind.
Although the pathogenesis of modern medicine to xerophthalmia has certain progress, think that the rising of tear osmotic pressure and tear film instability are the two large core mechanisms that xerophthalmia occurs, pathology pathogenesis is complicated.Drug therapy has: tear alternative medicine, anti-inflammatory drug as corticosteroid, tetracycline and derivant thereof, encircle mycin A, nonsteroidal antiinflammatory drug, cholinomimetic, androgen and estrogen etc.
But a lot of patient is after doctor trained in Western medicine ophthalmology is medical, therapeutic effect is not good, and the department of Chinese medicine is sought medical advice then.Ancient Chinese medicine doctor early has statement to this disease, and according to syndrome performance, xerophthalmia should belong to " oligodacrya " category.The traditional Chinese medical science thinks that the morbidity of xerophthalmia and the functional disorder of internal organs have substantial connection, because of the essence of five ZANG-organs and six FU-organs gas virtual loss, can not change spermatogenesis gas, cause supplementing nutrition and affecting visual function of order consumption of essence gas.Numerous doctor treats the main differentiation of symptoms and signs for classification of syndrome of xerophthalmia based on liver, kidney, deficiency of lung-YIN, in addition, also has insufficiency of the spleen, deficiency of both QI and YIN, deficiency of heart-QI and folder is wet, damp and hot, the floating pattern of syndrome such as to get over of the folder stasis of blood, phlegm and blood stasis, asthenic fire.
Deficiency of YIN damp-heat type xerophthalmia disease is seen: order pearl is dry, dry and astringent, pain, blurred vision, and eye secretion is thread, the glutinous or halitosis of mouth, and constipation is not well, dark coloured urine and short, and red tongue or tongue heel teeth print, the micro-Huang of tongue or yellow thick greasy summary are done, and thready pulse moistens number.
Summary of the invention
Inventor, according to oneself experience of taking up a job as a doctor for many years, based on organic conception and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, provides a kind of Chinese medicine preparation for the treatment of deficiency of YIN damp-heat type xerophthalmia.Inventor thinks damp being a kind of YIN pathogen, deep viscid, easily checks mechanism of qi, and eye ascending or descending movement of vital Qi is lacked of proper care, hematogenous blockage, then QI and blood is difficult to hold, and order pearl is dry, dry and astringent, pain; Damp violates order, and how viscid eye is and not well, and more, then blurred vision, eye secretion is thread to touching difficulty, doublely sees whole body damp-heat syndrome.Exogenous damp is accumulate for a long time, insufficiency of the spleen stranded, transporting mistake department, and can cause endogenous dampness, endogenous dampness is not changed, and increases the weight of exogenous damp again, upper general sick in order.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicine preparation for deficiency of YIN damp-heat type xerophthalmia, it is characterized in that: be made up of the medical material of following parts by weight: Rhizoma Atractylodis 11-16 part, Herba Plantaginis 20-25 part, Radix Stellariae Yunnanensis 10-15 part, Herba Eragrostidis Poaeoidis 13-18 part, Penthorum chinense 25-30 part, Semen Cassiae 25-30 part, Fructus Lycii 30-35 part, Flos Buddlejae 8-11 part.
Herba Plantaginis clearing away heat and promoting diuresis in side, Herba Eragrostidis Poaeoidis wind and heat dispersing, priming is up, and Semen Cassiae enters large intestine channel, clearing away heat to improve acuity of vision, and priming is descending, and Penthorum chinense is warm in nature can be mended, four medicine compatibilities are ready to accept a higher or a lower post, can dredge can fall apart, energy can mend clearly, damp is divided and rule, and mechanism of qi obtains freely.Be aided with Rhizoma Atractylodis drying damp and strengthening spleen, Radix Stellariae Yunnanensis spleen reinforcing spleen invigorating, spleen must be good for, so wet that to change.Radix Stellariae Yunnanensis and Fructus Lycii share nourishing the liver and kidney, make tearization active.Flos Buddlejae and Fructus Lycii share liver heat removing nourishing the liver, and adopting both clearing heat method and tonification method is share with Radix Stellariae Yunnanensis, and tonifying liver nourishes blood, and liver blood foot then order obtains blood, visual acuity is obtained from the sufficient blood supply of the eyes.Full side plays nourishing YIN and dispelling dampness altogether, invigorating the spleen for eliminating dampness, makes body fluid biochemistry active, and exopathogen is evacuated to be had, and mechanism of qi a surname is smooth.
Be the function and effect of each medical material in the present invention below:
Rhizoma Atractylodis: pungent, bitter, temperature.Return spleen, stomach, Liver Channel.Function cures mainly: drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia.
Herba Plantaginis: sweet, cold.Return liver, spleen channel.Function cures mainly: diuretic, heat clearing away, and improving eyesight is eliminated the phlegm.Control urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, jaundice, edema, hot meat, has loose bowels, epistaxis, conjunctival congestion and swelling pain, sore throat tonsillitis, cough, skin ulcer.
Radix Stellariae Yunnanensis: sweet; Flat.Return liver,spleen,kidney warp.Function cures mainly: strengthening spleen and nourishing blood; The liver and the kidney tonifying; Detumescence.Main anemia; Spirit is deficient; Dizzy nervous; Tinnitus dim eyesight; Hectic fever; Seminal emission; Menoxenia; Leukorrhagia; Fracture; Mastitis.
Herba Eragrostidis Poaeoidis: light; Cool.Function cures mainly: wind and heat dispersing; Removing heat from blood; Diuresis.The red nebula of argument; Metrorrhagia; Pyretic stranguria; Dysuria.
Penthorum chinense: sweet, temperature.Return liver, kidney channel.Function cures mainly: diuretic dehumidifies, stasis-dispelling and pain-killing.For jaundice, edema; Traumatic injury is controlled in external.
Semen Cassiae: sweet, bitter, salty, is slightly cold.Return liver, large intestine channel.Function cures mainly: clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.For the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, constipation.
Fructus Lycii: sweet is flat.Return liver, kidney channel.Function cures mainly: nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.
Flos Buddlejae: sweet, is slightly cold.Return Liver Channel.Function cures mainly: heat clearing away nourishing the liver, improving acuity of vision and removing nebula.For conjunctival congestion and swelling pain, many tear photophobia, nebula of looking unfamiliar film, hepatasthenia dim eyesight, blurring of vision.
Inventor with Chinese medicine preparation of the present invention to the curative effect of deficiency of YIN damp-heat type patients with dry eye for condition is to invention has been preferably, preferably, the Chinese medicine preparation for the treatment of deficiency of YIN damp-heat type xerophthalmia described above, is characterized in that: be made up of the medical material of following parts by weight: Rhizoma Atractylodis 13 parts, Herba Plantaginis 22 parts, Radix Stellariae Yunnanensis 14 parts, Herba Eragrostidis Poaeoidis 16 parts, Penthorum chinense 27 parts, Semen Cassiae 28 parts, Fructus Lycii 34 parts, Flos Buddlejae 10 parts.
The preparation method of the Chinese medicine preparation for the treatment of deficiency of YIN damp-heat type xerophthalmia of the present invention comprises the steps: described Rhizoma Atractylodis, Herba Plantaginis, Radix Stellariae Yunnanensis, Herba Eragrostidis Poaeoidis, Penthorum chinense, Semen Cassiae, Fructus Lycii and Flos Buddlejae are soaked in water 1 ~ 2 hour, amount of water is 6 ~ 10 times of medical material gross weight described above, decoct 1.5 ~ 2 hours, pour out decocting liquid, add medical material gross weight 5-8 described above water doubly again and continue decoction 1 hour, merge twice decocting liquid, filter, being evaporated to relative density is 1.10 ~ 1.30(60 DEG C) clear paste, soft material made by the ethanol adding 95% concentration add dextrin mixing in clear paste after again, sieve series becomes granule, dry, conventional Chinese medicine peroral dosage form is clinically prepared by Chinese medicine preparation common process.
Drug excipient is added in peroral dosage form described above.Preferably, described excipient is one or more in the middle of flavoring agent, dispersant, binding agent, thickening agent, lubricant, diluent.
Conventional Chinese medicine peroral dosage form can be any one in the middle of pill, tablet, granule, capsule clinically.
Preferably, Chinese medicine composition of the present invention is prepared into granule according to Chinese medicine preparation conventional fabrication process.
We are analyzed Chinese medicine preparation of the present invention by clinical observation.
Clinical observation material is as follows:
1. physical data: the case of collection is from the deficiency of YIN damp-heat type patients with dry eye of in March, 2013 ~ 2014 year March at my institute's ophthalmology outpatient clinic.Adopt the method for simple randomization controlled observation, in single even-numbered days on date of going to a doctor according to patient, case is divided into treatment group and matched group.Treatment group 40 example, man 15 example, female 25 example; Minimum 22 years old of age, maximum 64 years old; The course of disease is the shortest 4 months, the longest 5 years.Matched group 40 example, man 14 example, female 26 example; Minimum 20 years old of age, maximum 66 years old; The course of disease is the shortest 3 months, the longest 5 years.Two groups of patients are without general immunity disease.Two groups of sexes, age, courses of disease etc. are no difference of science of statistics (P > 0.05) all, has comparability.
2. diagnostic criteria: " the Chinese medical disease Standardization of diagnosis and curative effect " issued with reference to State Administration of Traditional Chinese Medicine: (1) symptom: eye is dry and astringent, foreign body sensation, asthenopia, can with mouth and nose drying etc.; (2) lacrimal secretion quantitative determination (Schirmer method) is lower than 10 ml/5 min; (3) breakup time of tear film (BUT) is less than 10 s; (4) corneal fluorescein sodium dyeing (FL) afterwards visible corneal epithelium to be dispersed in point-like painted.In above 4 arbitrarily, 2 positives are as case selection standard, meet differential diagnosis in tcm standard: be that disease is seen: order pearl is dry, dry and astringent, pain, blurred vision according to formulating the diagnostic criteria of deficiency of YIN damp-heat type with " Diagnostics of Chinese Medicine (the 2nd edition) " (DENG Tie-tao, Shanghai science tech publishing house) simultaneously, eye secretion is thread, mouthful glutinous or halitosis, constipation is not well, dark coloured urine and short, red tongue or tongue heel teeth print, the micro-Huang of tongue or yellow thick greasy summary are done, and thready pulse moistens number.
3. treatment and care method: treatment group patient takes granule prepared by the embodiment of the present invention 1, a day twice, each a bag, associating eyes Topical dextran hyprolose eye drop, every day 3 ~ 4 times, each 1 ~ 2.Matched group: simple eyes drip with dextran hyprolose eye drop, the same treatment group of usage and dosage.Two groups equal 30 days is a course for the treatment of.
4. statistical method: adopt SPSS16.0 software to analyze, measurement data with (
) represent, compare employing independent samples t test between group, compare in group with paired t-test, represent that difference has statistical significance with P < 0.05.
5. result of the test
5.1 curative effect judging standards: the industry standard " Chinese medical disease Standardization of diagnosis and curative effect " of promulgating with reference to State Administration of Traditional Chinese Medicine.Effective: subjective symptoms disappears, Schirmer tests > 10ml/5min or BUT>10s, the painted minimizing of corneal fluorescein or disappearance; Effective: subjective symptoms alleviates, Schirmer tests 5 ~ 10ml/5min or BUT>10s, the painted minimizing of corneal fluorescein; Invalid: subjective symptoms is without improvement, and Schirmer many mensuration lacrimal secretions do not increase or < 5ml/5min, BUT are unchanged or < 10 s, and corneal fluorescein dyeing is unchanged.
5.2 liang group observation index comparison: two groups treat a course for the treatment of after, treatment group, matched group curative effect in table 1,2.Ratio before BUT, SIt, FL and treatment after two groups of treatments, difference all has statistical significance (P < 0.05); Compare between BUT, Sit, FL two groups after treatment, difference all has statistical significance (P < 0.05).The total effective rate for the treatment of group and matched group is 97.5% and 77.5% respectively, and treatment group curative effect is obviously better than matched group, and two groups of differences comparing total effective rate have statistical significance (P < 0.05).
Before and after table 1 liang group treatment, BUT, SIt, FL compare
Compare with before treatment, * P < 0.05; #P < 0.05 is compared with matched group after treatment.
5.3 liang of group Clinical efficacy comparisons: total effective rate treatment group is 97.5%, and matched group is 77.5%; Two groups are compared, and difference has significant (P < 0.05).
Table 2 liang group Clinical efficacy comparison
In addition, carry out the conventional and Liver and kidney function of blood, urine, feces for primary disease, the relevant physico-chemical examination such as electrocardiogram, carries out treatment cross-reference, and without any ANOMALOUS VARIATIONS, nothing such as to affect the treatment at the untoward reaction.
Brief summary: as can be seen here, this Chinese medicine preparation is in the prolongation tear film broken time, and increase tear flow, improve the aspects such as corneal dyeing, be all significantly improved effect.Treatment to xerophthalmia: through statistics obvious effective rate 75.0%, effective percentage is 22.5%, and total effective rate is 97.5%.Therefore, present invention also offers a kind of pharmaceutical applications, that is: the application of above-mentioned Chinese medicine preparation in the medicine of preparation treatment deficiency of YIN damp-heat type xerophthalmia.
Beneficial effect of the present invention: Chinese medicine preparation treatment deficiency of YIN damp-heat type xerophthalmia clinical efficacy of the present invention is remarkable, effectively can increase lacrimal secretion, extend breakup time of tear film, there is nourishing YIN and dispelling dampness, invigorating the spleen for eliminating dampness, make body fluid biochemistry active, exopathogen is evacuated to be had, mechanism of qi a surname is smooth, and fundamentally reach the object of curing xerophthalmia, this Chinese medicine preparation is regular dosage form in addition, carry taking convenience, can preserve for a long time, avoid long-term taking Chinese medicine decoction and to boil medicine trouble, patient takes the shortcoming of compliance difference.
Detailed description of the invention
Be below specific embodiments of the invention and clinical practice example, technical scheme of the present invention and technique effect are done and describes further, but protection scope of the present invention be not limited to these embodiments.Every do not deviate from the present invention's design change or equivalent substituting include within protection scope of the present invention.
Embodiment 1
Get Rhizoma Atractylodis 13 parts by weight, Herba Plantaginis 22 parts, Radix Stellariae Yunnanensis 14 parts, Herba Eragrostidis Poaeoidis 16 parts, Penthorum chinense 27 parts, Semen Cassiae 28 parts, Fructus Lycii 34 parts and Flos Buddlejae 10 parts, be soaked in water 2 hours, amount of water is 10 times of medical material gross weight described above, decoct 1.5 hours, pour out decocting liquid, the water adding medical material gross weight described above 5 times again continues decoction 1 hour, merge twice decocting liquid, filter, being evaporated to relative density is 1.15(60 DEG C) clear paste, soft material made by the ethanol adding 95% concentration add appropriate dextrin and flavoring agent mixing in clear paste after again, sieve series becomes granule, dry, granule 10 bags is prepared by Chinese medicine preparation common process.
Embodiment 2
Get Rhizoma Atractylodis 11 parts by weight, Herba Plantaginis 20 parts, Radix Stellariae Yunnanensis 10 parts, Herba Eragrostidis Poaeoidis 13 parts, Penthorum chinense 25 parts, Semen Cassiae 25 parts, Fructus Lycii 30 parts and Flos Buddlejae 8 parts, be soaked in water 1 hour, amount of water is 8 times of medical material gross weight described above, decoct 1.5 hours, pour out decocting liquid, the water adding medical material gross weight described above 6 times again continues decoction 1 hour, merge twice decocting liquid, filter, being evaporated to relative density is 1.20(60 DEG C) clear paste, soft material made by the ethanol adding 95% concentration add appropriate dextrin and flavoring agent mixing in clear paste after again, sieve series becomes granule, dry, granule is prepared by Chinese medicine preparation common process.
Embodiment 3
Get Rhizoma Atractylodis 16 parts by weight, Herba Plantaginis 25 parts, Radix Stellariae Yunnanensis 15 parts, Herba Eragrostidis Poaeoidis 18 parts, Penthorum chinense 30 parts, Semen Cassiae 30 parts, Fructus Lycii 35 parts and Flos Buddlejae 11 parts, be soaked in water 1.5 hours, amount of water is 6 times of medical material gross weight described above, decoct 2 hours, pour out decocting liquid, the water adding medical material gross weight described above 8 times again continues decoction 1 hour, merge twice decocting liquid, filter, being evaporated to relative density is 1.17(60 DEG C) clear paste, soft material made by the ethanol adding 95% concentration add appropriate dextrin and flavoring agent mixing in clear paste after again, sieve series becomes granule, dry, granule is prepared by Chinese medicine preparation common process.
Embodiment 4
Get Rhizoma Atractylodis 11 parts by weight, Herba Plantaginis 25 parts, Radix Stellariae Yunnanensis 15 parts, Herba Eragrostidis Poaeoidis 13 parts, Penthorum chinense 30 parts, Semen Cassiae 30 parts, Fructus Lycii 30 parts and Flos Buddlejae 11 parts, be soaked in water 2 hours, amount of water is 8 times of medical material gross weight described above, decoct 1.5 hours, pour out decocting liquid, the water adding medical material gross weight described above 5 times again continues decoction 1 hour, merge twice decocting liquid, filter, being evaporated to relative density is 1.25(60 DEG C) clear paste, soft material made by the ethanol adding 95% concentration add appropriate dextrin and flavoring agent mixing in clear paste after again, sieve series becomes granule, dry, granule is prepared by Chinese medicine preparation common process.
Embodiment 5
Get Rhizoma Atractylodis 16 parts by weight, Herba Plantaginis 25 parts, Radix Stellariae Yunnanensis 10 parts, Herba Eragrostidis Poaeoidis 18 parts, Penthorum chinense 30 parts, Semen Cassiae 30 parts, Fructus Lycii 35 parts and Flos Buddlejae 11 parts, be soaked in water 2 hours, amount of water is 10 times of medical material gross weight described above, decoct 1.5 hours, pour out decocting liquid, the water adding medical material gross weight described above 5 times again continues decoction 1 hour, merge twice decocting liquid, filter, being evaporated to relative density is 1.10(60 DEG C) clear paste, soft material made by the ethanol adding 95% concentration add appropriate dextrin and flavoring agent mixing in clear paste after again, sieve series becomes granule, dry, granule is prepared by Chinese medicine preparation common process.
Embodiment 6
Get Rhizoma Atractylodis 15 parts by weight, Herba Plantaginis 23 parts, Radix Stellariae Yunnanensis 13 parts, Herba Eragrostidis Poaeoidis 14 parts, Penthorum chinense 26 parts, Semen Cassiae 30 parts, Fructus Lycii 35 parts and Flos Buddlejae 9 parts, be soaked in water 2 hours, amount of water is 8 times of medical material gross weight described above, decoct 1.5 hours, pour out decocting liquid, the water adding medical material gross weight described above 5 times again continues decoction 1 hour, merge twice decocting liquid, filter, being evaporated to relative density is 1.10(60 DEG C) clear paste, soft material made by the ethanol adding 95% concentration add appropriate dextrin and flavoring agent mixing in clear paste after again, sieve series becomes granule, dry, add appropriate silicon dioxide, capsule is prepared by Chinese medicine preparation common process.
Claims (6)
1. treat a Chinese medicine preparation for deficiency of YIN damp-heat type xerophthalmia, it is characterized in that being made up of the raw material of following weight portion: Rhizoma Atractylodis 11-16 part, Herba Plantaginis 20-25 part, Radix Stellariae Yunnanensis 10-15 part, Herba Eragrostidis Poaeoidis 13-18 part, Penthorum chinense 25-30 part, Semen Cassiae 25-30 part, Fructus Lycii 30-35 part, Flos Buddlejae 8-11 part.
2. the Chinese medicine preparation for the treatment of deficiency of YIN damp-heat type xerophthalmia as claimed in claim 1, is characterized in that being made up of the raw material of following weight portion: Rhizoma Atractylodis 13 parts, Herba Plantaginis 22 parts, Radix Stellariae Yunnanensis 14 parts, Herba Eragrostidis Poaeoidis 16 parts, Penthorum chinense 27 parts, Semen Cassiae 28 parts, Fructus Lycii 34 parts, Flos Buddlejae 10 parts.
3. treat the preparation method of the Chinese medicine preparation of deficiency of YIN damp-heat type xerophthalmia as claimed in claim 1 or 2 for one kind, it is characterized in that comprising the steps: the Rhizoma Atractylodis by described, Herba Plantaginis, Radix Stellariae Yunnanensis, Herba Eragrostidis Poaeoidis, Penthorum chinense, Semen Cassiae, Fructus Lycii and Flos Buddlejae are soaked in water 1-2 hour, amount of water is 6-10 times of medical material gross weight described above, decoct 1.5-2 hour, pour out decocting liquid, add medical material gross weight 5-8 described above water doubly again and continue decoction 1 hour, merge twice decocting liquid, filter, when being evaporated to 60 DEG C, relative density is the clear paste of 1.10-1.30, soft material made by the ethanol adding 95% concentration add dextrin mixing in clear paste after again, sieve series becomes granule, dry, conventional Chinese medicine peroral dosage form is clinically prepared by Chinese medicine preparation common process.
4. the Chinese medicine preparation for the treatment of deficiency of YIN damp-heat type xerophthalmia as claimed in claim 1 or 2, is characterized in that: described Chinese medicine preparation is pill, tablet, granule or capsule.
5. the Chinese medicine preparation for the treatment of deficiency of YIN damp-heat type xerophthalmia as claimed in claim 4, is characterized in that: described Chinese medicine preparation is granule.
6. described in claim 1 or 2, treat the application of Chinese medicine preparation in the medicine of preparation treatment deficiency of YIN damp-heat type xerophthalmia of deficiency of YIN damp-heat type xerophthalmia.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104971158A (en) * | 2015-07-25 | 2015-10-14 | 孟根森 | Traditional Chinese medicine for treating dry eyes |
| CN105708924A (en) * | 2016-04-20 | 2016-06-29 | 辛莉 | Traditional Chinese medicine for treating xerophthalmia caused by deficiency of both qi and yin |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103393915A (en) * | 2013-07-20 | 2013-11-20 | 房进彩 | Chinese medicinal preparation for treating xerophthalmia |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103393915A (en) * | 2013-07-20 | 2013-11-20 | 房进彩 | Chinese medicinal preparation for treating xerophthalmia |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104971158A (en) * | 2015-07-25 | 2015-10-14 | 孟根森 | Traditional Chinese medicine for treating dry eyes |
| CN105708924A (en) * | 2016-04-20 | 2016-06-29 | 辛莉 | Traditional Chinese medicine for treating xerophthalmia caused by deficiency of both qi and yin |
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