CN104383217A - 一种用于治疗脚气的中药组合物及其制备方法 - Google Patents

一种用于治疗脚气的中药组合物及其制备方法 Download PDF

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CN104383217A
CN104383217A CN201410617210.5A CN201410617210A CN104383217A CN 104383217 A CN104383217 A CN 104383217A CN 201410617210 A CN201410617210 A CN 201410617210A CN 104383217 A CN104383217 A CN 104383217A
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孙俊
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Liu Yongqiu
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Abstract

本发明涉及一种用于治疗脚气的中药组合物，由以下组分按照重量分数组成：升麻3-10份，蒲公英10-30份，穿心莲5-15份，浮萍5-15份，苦参3-9份，土茯苓15-25份；白花蛇3-9份，地肤子5-15份，血竭2-4份；赤石脂5-15份，海螵蛸3-9份，地榆5-15份、陈醋400-600份。本发明组合物的优势是：按中医理配制而成，组方合理；清热解毒、祛风除湿、止血敛疮，针对性强；中药制剂，毒副作用小；超微粉碎，有效释放药物有效成分。

Description

一种用于治疗脚气的中药组合物及其制备方法
技术领域
本发明涉及治疗脚气的中药制剂，特别涉及一种用于治疗脚气的中药组合物及其制备方法。
背景技术
脚气，它是由多种因素造成脚痒、缺乏维生素；手足癣是常见皮肤病有皮肤真菌感染引起，中医认为手癣是鹅掌风；足癣是湿脚气。足癣常见脚长时间处于潮湿鞋内，趾缝发痒，脚部受真菌感染，出现粟粒大小水泡；手癣多受脚癣传染所致，此种病冬季症状减轻，入夏症状加剧，部分患者可出现皮肤干裂。祖国传统中医学认为湿热下注，水液浸渍，引起脚丫潮湿，作痒难忍，往往搓至皮烂疼痛，流出水血，经年不愈，俗称“湿气”严重的腐烂疼痛，足趾浮肿，流脓淌水，臭味难闻，行走不便。社会上治疗此种病的药物多种多样，但疗效不一。
发明内容
针对现有技术中存在的缺陷，本发明的目的在于提供一种用于治疗脚气的中药组合物及其制备方法。
本发明的技术方案如下：
一种用于治疗脚气的中药组合物由以下组分组成：
升麻，蒲公英，穿心莲，浮萍，苦参，土茯苓；白花蛇，地肤子，血竭；赤石脂，海螵蛸，地榆、陈醋。
在上述方案的基础上，一种用于治疗脚气的中药组合物，由以下组分按照重量分数组成：
升麻3-10份，蒲公英10-30份，穿心莲5-15份，浮萍5-15份，苦参3-9份，土茯苓15-25份；白花蛇3-9份，地肤子5-15份，血竭2-4份；赤石脂5-15份，海螵蛸3-9份，地榆5-15份、陈醋400-600份。
在上述方案的基础上，一种用于治疗脚气的中药组合物，由以下组分按照重量分数组成：
升麻6份，蒲公英20份，穿心莲10份，浮萍10份，苦参6份，土茯苓20份；白花蛇6份，地肤子10份，血竭3份；赤石脂10份，海螵蛸6份，地榆10份、陈醋500份。
一种用于治疗脚气的中药组合物，具体的制备放如下：
1)按照上述组合物的重量份数称取各种组分；
2)将各组分(除血竭、赤石脂和海螵蛸外)超微粉碎至200目，将血竭、赤石脂和海螵蛸粉碎至400目；
3)将粉碎后的血竭、赤石脂和海螵蛸加入到陈醋中，搅拌均匀，浸泡2小时后煎煮20分钟，加入组合物中其他组分(除血竭、赤石脂和海螵蛸外)，继续煎煮10分钟；
4)冷却后密封保存。
上述方法制备的中药组合物在治疗脚气中的应用。
本发明组方按照中医理论配制而成，组合物中：升麻清热解毒、发表透疹、升阳举陷；蒲公英清热解毒、消痈散结、利湿通淋；穿心莲清热解毒、燥湿；取用三药的清热解毒之功，为君药；其中：浮萍透疹、祛风止痒、利水消肿；苦参清热燥湿、祛风杀虫、利尿；土茯苓解毒除湿；白花蛇祛风、活络；地肤子清热利水、止痒；五药佐君药祛风、止痒，为臣药；组方中：血竭内服活血散瘀止痛、外用止血生肌敛疮；赤石脂止血、收涩、生肌敛疮；海螵蛸收敛止血、收涩敛疮；地榆凉血止血、解毒敛疮；四药共为佐药；陈醋散瘀、止血、解毒、杀虫、抗菌、收敛，为引经药。十三味中药合用，共奏清热解毒、祛风除湿、止血敛疮之功效，可以有效治疗脚气。
本发明组合物的优势是：按中医理配制而成，组方合理；清热解毒、祛风除湿、止血敛疮，针对性强；中药制剂，毒副作用小；超微粉碎，有效释放药物有效成分。
具体实施方式
实施例1
一种用于治疗脚气的中药组合物，由以下组分按照重量分数组成(每份1g)：
升麻3份，蒲公英10份，穿心莲5份，浮萍5份，苦参3份，土茯苓15份；白花蛇3份，地肤子5份，血竭2份；赤石脂5份，海螵蛸3份，地榆5份、陈醋400份。
具体的制备放如下：
1)按照上述组合物的重量份数称取各种组分；
2)将各组分(除血竭、赤石脂和海螵蛸外)超微粉碎至200目，将血竭、赤石脂和海螵蛸粉碎至400目；
3)将粉碎后的血竭、赤石脂和海螵蛸加入到陈醋中，搅拌均匀，浸泡2小时后煎煮20分钟，加入组合物中其他组分(除血竭、赤石脂和海螵蛸外)，继续煎煮10分钟；
4)冷却后密封保存。
实施例2
一种用于治疗脚气的中药组合物，由以下组分按照重量分数组成(每份1g)：
升麻6份，蒲公英20份，穿心莲10份，浮萍10份，苦参6份，土茯苓20份；白花蛇6份，地肤子10份，血竭3份；赤石脂10份，海螵蛸6份，地榆10份、陈醋500份。
制备方法与实施例1相同。
实施例3
一种用于治疗脚气的中药组合物，由以下组分按照重量分数组成(每份1g)：
升麻10份，蒲公英30份，穿心莲15份，浮萍15份，苦参9份，土茯苓25份；白花蛇9份，地肤子15份，血竭4份；赤石脂15份，海螵蛸9份，地榆15份、陈醋600份。
制备方法与实施例1相同。
实验例：
(1)临床资料
本发明人于2010年至2012年，对200例脚气患者进行临床观察治疗，其中，男112例，女88例。
(2)治疗方法
使用本发明制备的中药浸泡患处，每日1剂，1剂一次，每次20分钟，浸泡后2小时不要洗脚，10天为一疗程，连续使用3个疗程。
(3)疗效判定标准
“治愈”：临床症状体征消失，恢复正常。
“显效”：临床症状体征基本或大部分消失。
“有效”：临床症状明显好转。
“无效”：临床症状体征无改善。
(4)治疗效果：
连续治疗三个疗程后，治愈84例；显效64例；有效47例；无效5例，总有效率97.5％。
典型病例：
1、李某，男，双脚趾间起水脓泡脱皮痒痛，左脚第3、4脚趾间糜烂1月，镜检真菌学阳性。使用本发明实施例2制备的药物治疗3个疗程后症状消失，复查真菌学检查阴性，1年内无复发。
2、陈某，女，患脚气2年，双脚起水泡痒痛，夏季更明显，使用本发明实施例2制备的中药浸泡患处，每日1剂，1剂一次，每次20分钟，10天为一疗程，连续使用3个疗程。3个疗程后瘙痒、水泡、糜烂、脱屑等均消失，1年后随访无复发。
以上所述，仅是本发明的较佳实施例而已，并非是对本发明作其它形式的限制，任何熟悉本专业的技术人员可能利用上述揭示的技术内容加以变更或改型为等同变化的等效实施例。但是凡是未脱离本发明技术方案内容，依据本发明的技术实质对以上实施例所作的任何简单修改、等同变化与改型，仍属于本发明技术方案的保护范围。

Claims (5)

1.一种用于治疗脚气的中药组合物，其特征在于由以下组分组成：
升麻，蒲公英，穿心莲，浮萍，苦参，土茯苓；白花蛇，地肤子，血竭；赤石脂，海螵蛸，地榆、陈醋。
2.根据权利要求1所述的一种用于治疗脚气的中药组合物，其特征在于由以下组分按照重量分数组成：
升麻3-10份，蒲公英10-30份，穿心莲5-15份，浮萍5-15份，苦参3-9份，土茯苓15-25份；白花蛇3-9份，地肤子5-15份，血竭2-4份；赤石脂5-15份，海螵蛸3-9份，地榆5-15份、陈醋400-600份。
3.根据权利要求1所述的用于治疗脚气的中药组合物，其特征在于由以下组分按照重量分数组成：
升麻6份，蒲公英20份，穿心莲10份，浮萍10份，苦参6份，土茯苓20份；白花蛇6份，地肤子10份，血竭3份；赤石脂10份，海螵蛸6份，地榆10份、陈醋500份。
4.一种根据权利要求1、2和3所述的用于治疗脚气的中药组合物，其特征在于具体的制备放如下：
1)按照权利要求2和3所述的重量份数称取各种组分；
2)将各组分(除血竭、赤石脂和海螵蛸外)超微粉碎至200目，将血竭、赤石脂和海螵蛸粉碎至400目；
3)将粉碎后的血竭、赤石脂和海螵蛸加入到陈醋中，搅拌均匀，浸泡2小时后煎煮20分钟，加入组合物中其他组分(除血竭、赤石脂和海螵蛸外)，继续煎煮10分钟；
4)冷却后密封保存。
5.权利要求4制备的中药组合物在治疗脚气中的应用。
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