CN104380095B - 具有改进的精度的电化学生物传感器 - Google Patents
具有改进的精度的电化学生物传感器 Download PDFInfo
- Publication number
- CN104380095B CN104380095B CN201380031465.7A CN201380031465A CN104380095B CN 104380095 B CN104380095 B CN 104380095B CN 201380031465 A CN201380031465 A CN 201380031465A CN 104380095 B CN104380095 B CN 104380095B
- Authority
- CN
- China
- Prior art keywords
- electrode
- reaction unit
- blood
- working electrode
- electrochemical biosensor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
- G01N27/3277—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a redox reaction, e.g. detection by cyclic voltammetry
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
- C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Diabetes (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020120059327A KR101466222B1 (ko) | 2012-06-01 | 2012-06-01 | 정확도가 향상된 전기화학적 바이오센서 |
| KR10-2012-0059327 | 2012-06-01 | ||
| PCT/KR2013/004838 WO2013180528A1 (ko) | 2012-06-01 | 2013-05-31 | 정확도가 향상된 전기화학적 바이오센서 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104380095A CN104380095A (zh) | 2015-02-25 |
| CN104380095B true CN104380095B (zh) | 2016-08-24 |
Family
ID=49673647
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380031465.7A Active CN104380095B (zh) | 2012-06-01 | 2013-05-31 | 具有改进的精度的电化学生物传感器 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US9753004B2 (enExample) |
| EP (1) | EP2871470B1 (enExample) |
| JP (1) | JP5873215B2 (enExample) |
| KR (1) | KR101466222B1 (enExample) |
| CN (1) | CN104380095B (enExample) |
| WO (1) | WO2013180528A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150140671A1 (en) * | 2013-11-18 | 2015-05-21 | Johnson Electric S.A. | Method and system for assembling a microfluidic sensor |
| KR101671456B1 (ko) * | 2014-07-11 | 2016-11-16 | 최강 | 바이오센서 |
| KR20160014212A (ko) * | 2014-07-28 | 2016-02-11 | 주식회사 아이센스 | 휴대용 혈당 측정기 |
| KR101666978B1 (ko) | 2014-09-17 | 2016-10-24 | 주식회사 아이센스 | 생체시료 내 분석대상물질의 농도측정방법 및 측정장치 |
| CN204142671U (zh) * | 2014-09-22 | 2015-02-04 | 英科新创(厦门)科技有限公司 | 电极式血糖试条 |
| CN104792993B (zh) * | 2015-03-14 | 2017-07-11 | 深圳市贝沃德克生物技术研究院有限公司 | 用于血糖仪试纸针的试纸条 |
| CN107427258B (zh) * | 2015-04-15 | 2021-03-02 | 株式会社村田制作所 | 呼气传感器、呼气传感器单元及呼气检测方法 |
| GB201511299D0 (en) * | 2015-06-26 | 2015-08-12 | Inside Biometrics Ltd | Test device and method of using a test device |
| TWI579562B (zh) * | 2015-11-11 | 2017-04-21 | Method of Making Electrochemistry Test Specimen | |
| WO2017106560A1 (en) * | 2015-12-18 | 2017-06-22 | Trividia Health, Inc. | In-vitro sensor using a tetrapolar impedance measurement |
| US10302587B2 (en) * | 2016-03-29 | 2019-05-28 | Broadmaster Biotech Corp. | Test strip and method of operation thereof |
| KR101875417B1 (ko) * | 2016-07-01 | 2018-07-10 | (주)오상헬스케어 | 바이오센서 |
| TWI589869B (zh) * | 2016-08-08 | 2017-07-01 | 友達光電股份有限公司 | 感測裝置及該感測裝置之電極試片 |
| WO2019017094A1 (ja) * | 2017-07-19 | 2019-01-24 | シャープ株式会社 | センサおよびセンサアレイ |
| KR102336969B1 (ko) * | 2017-07-20 | 2021-12-08 | 동우 화인켐 주식회사 | 글루코스 센서 |
| KR102459679B1 (ko) * | 2017-09-19 | 2022-10-27 | 동우 화인켐 주식회사 | 글루코스 센서 |
| KR102486571B1 (ko) * | 2017-10-24 | 2023-01-09 | 주식회사 미코바이오메드 | 바이오 측정 장치 |
| US11541385B2 (en) * | 2018-07-06 | 2023-01-03 | Qorvo Us, Inc. | Methods of measuring hematocrit in fluidic channels including conductivity sensor |
| KR102179203B1 (ko) * | 2018-07-09 | 2020-11-16 | 주식회사 필로시스 | 혈당 센싱 데이터 판별 방법 및 장치 |
| CN109061190B (zh) * | 2018-08-22 | 2021-12-07 | 苏州微湃医疗科技有限公司 | 基于纸芯片的多通道生物传感器阵列制备及免疫检测应用 |
| US12117435B2 (en) | 2018-11-02 | 2024-10-15 | Cardiai Technologies Ltd. | Portable electrochemical-sensor system for analyzing user health conditions and method thereof |
| KR102235310B1 (ko) | 2019-05-16 | 2021-04-01 | 단국대학교 천안캠퍼스 산학협력단 | 키토산-탄소나노튜브 코어-쉘 나노하이브리드 기반의 전기화학 글루코즈 센서 |
| EP3990894A1 (en) * | 2019-06-28 | 2022-05-04 | ProciseDx Inc. | Methods for accommodating for sample matrix effects in light measurement assays |
| CN112294318B (zh) | 2019-08-02 | 2024-08-20 | 华广生技股份有限公司 | 植入式微型生物传感器及其制法 |
| CN115078508B (zh) * | 2022-06-21 | 2024-01-19 | 爱森斯(江苏)生物科技有限公司 | 电化学生物传感器及其制备方法 |
| CN116026906A (zh) * | 2022-12-29 | 2023-04-28 | 苏州和林微纳科技股份有限公司 | 一种微流控血糖检测芯片 |
| CN115825178B (zh) * | 2023-01-11 | 2024-07-19 | 宁波康和长晟科技有限公司 | 一种基于自支撑葡萄糖电催化材料的电化学葡萄糖传感器 |
| KR102716109B1 (ko) * | 2023-12-06 | 2024-10-11 | 주식회사 에모닉 | 눈물 삼투압 센서 및 이의 제조 방법 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6287451B1 (en) * | 1999-06-02 | 2001-09-11 | Handani Winarta | Disposable sensor and method of making |
| CN1836159A (zh) * | 2003-06-20 | 2006-09-20 | 霍夫曼-拉罗奇有限公司 | 生物传感器及其制造方法 |
| US20090056120A1 (en) * | 1999-10-04 | 2009-03-05 | Bhullar Raghbir S | Biosensor and method of making |
| US7611621B2 (en) * | 2005-06-13 | 2009-11-03 | Nova Biomedical Corporation | Disposable oxygen sensor and method for correcting oxygen effect on oxidase-based analytical devices |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4301412A (en) | 1979-10-29 | 1981-11-17 | United States Surgical Corporation | Liquid conductivity measuring system and sample cards therefor |
| GB9309797D0 (en) | 1993-05-12 | 1993-06-23 | Medisense Inc | Electrochemical sensors |
| US6241862B1 (en) | 1996-02-14 | 2001-06-05 | Inverness Medical Technology, Inc. | Disposable test strips with integrated reagent/blood separation layer |
| JP3810534B2 (ja) * | 1997-10-17 | 2006-08-16 | 松下電器産業株式会社 | ヘマトクリット値測定用素子およびヘマトクリット値の測定方法 |
| US6475372B1 (en) | 2000-02-02 | 2002-11-05 | Lifescan, Inc. | Electrochemical methods and devices for use in the determination of hematocrit corrected analyte concentrations |
| JP2000338076A (ja) | 1999-05-25 | 2000-12-08 | Matsushita Electric Ind Co Ltd | バイオセンサ |
| DE60137787D1 (de) | 2000-09-20 | 2009-04-09 | Mikuni Kogyo Kk | Brennstofffilter |
| US7351323B2 (en) * | 2001-01-17 | 2008-04-01 | Arkray, Inc. | Quantitative analyzing method and quantitative analyzer using sensor |
| US6837976B2 (en) * | 2002-04-19 | 2005-01-04 | Nova Biomedical Corporation | Disposable sensor with enhanced sample port inlet |
| US7501053B2 (en) * | 2002-10-23 | 2009-03-10 | Abbott Laboratories | Biosensor having improved hematocrit and oxygen biases |
| KR100554649B1 (ko) * | 2003-06-09 | 2006-02-24 | 주식회사 아이센스 | 전기화학적 바이오센서 |
| US7452457B2 (en) * | 2003-06-20 | 2008-11-18 | Roche Diagnostics Operations, Inc. | System and method for analyte measurement using dose sufficiency electrodes |
| US7867369B2 (en) * | 2003-06-20 | 2011-01-11 | Roche Diagnostics Operations, Inc. | Biosensor with multiple electrical functionalities |
| EP2579031B1 (en) * | 2003-12-04 | 2017-09-27 | Panasonic Healthcare Holdings Co., Ltd. | Biosensor for measuring blood component and hematocrit. |
| KR100586832B1 (ko) * | 2004-08-27 | 2006-06-08 | 주식회사 인포피아 | 바이오센서의 시료반응결과 측정장치 |
| KR100581748B1 (ko) | 2004-09-24 | 2006-05-22 | 한상배 | 자흡기능과 교반기능이 구비된 유체공급장치와 이를이용한 포기장치 |
| KR100698961B1 (ko) * | 2005-02-04 | 2007-03-26 | 주식회사 아이센스 | 전기화학적 바이오센서 |
| KR100851131B1 (ko) | 2005-08-17 | 2008-08-08 | 가부시키가이샤 고베 세이코쇼 | 소스/드레인 전극, 박막 트랜지스터 기판, 그의 제조방법,및 표시 디바이스 |
| KR101203848B1 (ko) | 2005-08-31 | 2012-11-21 | 엘지전자 주식회사 | 멀티형 공기조화기의 압축기 오일 회수장치 |
| KR100824691B1 (ko) | 2005-09-13 | 2008-04-24 | 전달용 | 수익 자동 배분 방법 및 시스템 |
| US8617366B2 (en) * | 2005-12-12 | 2013-12-31 | Nova Biomedical Corporation | Disposable urea sensor and system for determining creatinine and urea nitrogen-to-creatinine ratio in a single device |
| WO2008040982A1 (en) * | 2006-10-05 | 2008-04-10 | Lifescan Scotland Limited | Method for determining hematocrit corrected analyte concentrations |
| KR20070020447A (ko) | 2006-11-07 | 2007-02-21 | 지. 톰프슨 로저 | 즉각적으로 착용할 수 있는 표식을 가진 모자 챙 성형 장치 |
| KR100890988B1 (ko) * | 2007-10-29 | 2009-03-31 | 주식회사 아이센스 | 일정 소량의 시료를 균일하게 도입할 수 있는 시료도입부를구비한 전기화학적 바이오센서 |
| JP2010230369A (ja) * | 2009-03-26 | 2010-10-14 | Ryukoku Univ | 電極構造及び当該電極構造の製造方法並びに電気化学センサ |
| TWI440853B (zh) * | 2009-12-14 | 2014-06-11 | Taidoc Technology Corp | 具有校正血容比功能之分析物測量電化學生物感測試紙、生物感測器裝置、系統以及測量方法 |
| KR101979680B1 (ko) | 2012-12-05 | 2019-05-20 | 삼성전자주식회사 | 촉각센서 |
-
2012
- 2012-06-01 KR KR1020120059327A patent/KR101466222B1/ko active Active
-
2013
- 2013-05-31 JP JP2015514916A patent/JP5873215B2/ja not_active Expired - Fee Related
- 2013-05-31 EP EP13796996.0A patent/EP2871470B1/en active Active
- 2013-05-31 WO PCT/KR2013/004838 patent/WO2013180528A1/ko not_active Ceased
- 2013-05-31 CN CN201380031465.7A patent/CN104380095B/zh active Active
-
2014
- 2014-12-01 US US14/556,891 patent/US9753004B2/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6287451B1 (en) * | 1999-06-02 | 2001-09-11 | Handani Winarta | Disposable sensor and method of making |
| US20090056120A1 (en) * | 1999-10-04 | 2009-03-05 | Bhullar Raghbir S | Biosensor and method of making |
| CN1836159A (zh) * | 2003-06-20 | 2006-09-20 | 霍夫曼-拉罗奇有限公司 | 生物传感器及其制造方法 |
| US7611621B2 (en) * | 2005-06-13 | 2009-11-03 | Nova Biomedical Corporation | Disposable oxygen sensor and method for correcting oxygen effect on oxidase-based analytical devices |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013180528A1 (ko) | 2013-12-05 |
| JP5873215B2 (ja) | 2016-03-01 |
| KR101466222B1 (ko) | 2014-12-01 |
| EP2871470A1 (en) | 2015-05-13 |
| US9753004B2 (en) | 2017-09-05 |
| KR20130135605A (ko) | 2013-12-11 |
| CN104380095A (zh) | 2015-02-25 |
| EP2871470B1 (en) | 2016-07-20 |
| US20150083613A1 (en) | 2015-03-26 |
| EP2871470A4 (en) | 2015-06-03 |
| JP2015518161A (ja) | 2015-06-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104380095B (zh) | 具有改进的精度的电化学生物传感器 | |
| JP4418435B2 (ja) | 電気化学的バイオセンサー | |
| JP4018082B2 (ja) | 電気化学バイオセンサ | |
| AU2016200530B2 (en) | Accurate analyte measurements for electrochemical test strip based on sensed physical characteristic(s) of the sample containing the analyte | |
| CN1981192B (zh) | 检测生物分析物的伏安测量系统 | |
| CN1514937A (zh) | 电化学生物传感器 | |
| AU2011303639B2 (en) | Analyte measurement method and system with hematocrit compensation | |
| JP4927996B2 (ja) | 一定少量の試料を均一に導入可能な試料導入チャンネルを具備した電気化学的バイオセンサ | |
| CN107422019A (zh) | 电化学测试片 | |
| CN203535003U (zh) | 一种生物传感器 | |
| EP2232250A1 (en) | Methods and systems for forming reagent with reduced background current | |
| D’Orazio | Electrochemical sensors: a review of techniques and applications in point of care testing | |
| CN203534868U (zh) | 一种生物传感器 | |
| KR101671456B1 (ko) | 바이오센서 | |
| CN101162213A (zh) | 生物传感器 | |
| HK1235857A1 (en) | Blood glucose measurements for electrochemical test strip based on sensed hematocrit and derived biosensor parameters |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant |