CN104367944B - 一种治疗腰椎间盘突出症的药物 - Google Patents

一种治疗腰椎间盘突出症的药物 Download PDF

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CN104367944B
CN104367944B CN201410618579.8A CN201410618579A CN104367944B CN 104367944 B CN104367944 B CN 104367944B CN 201410618579 A CN201410618579 A CN 201410618579A CN 104367944 B CN104367944 B CN 104367944B
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李满荣
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Abstract

本发明公开了一种毒副作用小的治疗腰椎间盘突出症的药物。它由下述重量份的原料制成：熟地20‑30份、枣皮15‑20份、山药20‑30份、丹皮12‑15份、茯苓12‑15份、泽泻12‑15份、独活12‑15份、川牛膝12‑15份、杜仲12‑15份、制马钱子12‑15份、狗脊12‑15份、地龙12‑15份、伸筋草12‑15份、炮山甲8‑10份、土元12‑15份、白芍15‑20份、生白术12‑15份、红花10‑12份、砂仁12‑15份、莪术12‑15份、甘草6‑8份。本方虽药味偏多，但组方严谨，肝脾肾同补，治病求本，标本兼施，无过寒过热及峻猛之品，虽有制马钱子，有毒，但药量少，具有恢复、调节腰椎神经作用，和上述药配伍以增强疗效。

Description

一种治疗腰椎间盘突出症的药物
技术领域
本发明属于一种中药，特别涉及一种治疗腰椎间盘突出症的中成药。
背景技术
腰椎间盘突出症，传统中医称之为“腰痛”、“痹证”的范畴，是以腰痛伴下肢疼痛，或麻木，或小腹痛及大小便异常，为主要特征的疾病，本病表现顽固，病程长，易复发。
祖国医学及中医理论认为“腰痛”、“痹症”无论何种原因导致腰痛，肾虚均为致病原因，所谓“邪之所凑，其气必虚，无肾病，虽感寒湿，也甚少出现此病，故中老年或体弱者多见之，故当补肾强腰为主。发明人认为肾气亏虚，致风寒湿邪或跌扑劳损久治不愈，郁结腰府，不通则痛，久则麻木不仁是本病发病转归中的重要环节。
目前，公认用于治疗腰椎间盘突出症的中成药主要有 “腰痛宁”、“根痛平”等，大多药共有不足是，在治疗原理限于祛风通络，活血止痛，大多过于辛燥，很难控制病情的反复发作，即不能标本兼治，切治愈率低，不能适应临床治疗需要。
发明内容
本发明的目的是提供一种毒副作用小的治疗腰椎间盘突出症的药物。
本发明是以如下技术方案实现的：一种治疗腰椎间盘突出症的药物，它由下述重量份的原料制成：
熟地20-30份、枣皮15-20份、山药20-30份、丹皮12-15份、茯苓12-15份、泽泻12-15份、独活12-15份、川牛膝12-15份、杜仲12-15份、制马钱子12-15份、狗脊12-15份、地龙12-15份、伸筋草12-15份、炮山甲8-10份、土元12-15份、白芍15-20份、生白术12-15份、红花10-12份、砂仁12-15份、莪术12-15份、甘草6-8份。
优选由下述重量份的原料制成：熟地30份、枣皮20份、山药30份、丹皮15份、茯苓15份、泽泻15份、独活15份、川牛膝15份、杜仲15份、制马钱子15份、狗脊15份、地龙15份、伸筋草15份、炮山甲10份、土元15份、白芍20份、生白术15份、红花12份、砂仁15份、莪术15份、甘草8份。
上述的一种治疗腰椎间盘突出症的药物，其剂型为胶囊，是制备方法：将制马钱子、炮山甲、地龙、土元分别研磨成细粉，将茯苓、泽泻、熟地、枣皮、山药、丹皮、独活、川牛膝、杜仲、狗脊、伸筋草、白芍、生白术、红花、砂仁、莪术、甘草十七味药混合研磨成细粉，胶囊内所述的各组分的药物均为细度不低于80目的粉状混合物。
本发明机理如下：本发明人认为肾气亏虚，致风寒湿邪或跌扑劳损久治不愈，郁结腰府，气滞血瘀是本病的起因，故本方以滋补肝肾、活血通络、祛风除湿、和胃调中为治疗法则。熟地、枣皮、山药以补肾滋肝健脾为君；狗脊、杜仲、川牛膝为臣，助主药健腰补肾，并引药之腰腑；佐以制乳香、红花、炮山甲、地龙、土元活血通络止痛；佐以独活、制马钱子祛风胜湿；莪术、丹皮、白芍、甘草消肿散结、柔肝止痛；使药 茯苓、砂仁、生白术、泽泻健脾调中。本方虽药味偏多，但组方严谨，肝脾肾同补，治病求本，标本兼施，无过寒过热及峻猛之品，虽有制马钱子，有毒，但药量少，具有恢复、调节腰椎神经作用，和上述药配伍以增强疗效。
本发明的优点是标本兼治，治愈率高，复发率低，毒副作用小。
具体实施方式
下面结合实施例及临床实验例进一步详述本发明及其效果。
实施例1.组方：熟地30g、枣皮20g、山药30g、丹皮15g、茯苓15g、泽泻15g、独活15g、川牛膝15g、杜仲15g、制马钱子15g、狗脊15g、地龙15g、伸筋草15g、炮山甲10g、土元15g、白芍20g、生白术15g、红花12g、砂仁15g、莪术15g、甘草8g。次方效果最佳。
实施例2. 组方：熟地20g、枣皮15g、山药20g、丹皮12g、茯苓12g、泽泻12g、独活12g、川牛膝12g、杜仲12g、制马钱子12g、狗脊12g、地龙12g、伸筋草12g、炮山甲8g、土元12g、白芍15g、生白术12g、红花10g、砂仁12g、莪术12g、甘草6g。次方药性稍弱，可针对症状轻的患者使用。
实施例3. 组方：熟地30g、枣皮20g、山药30g、丹皮15g、茯苓15g、泽泻15g、独活15g、川牛膝15g、杜仲15g、制马钱子15g、狗脊15g、地龙15g、伸筋草15g、炮山甲10g、土元15g、白芍20g、生白术15g、红花12g、砂仁15g、莪术15g、甘草8g。次方药性较强，可针对症状重的患者使用。
上述实施例可制成胶囊剂型，制备方法如下：将制马钱子、炮山甲、地龙、土元分别研磨成细粉，将茯苓、泽泻、熟地、枣皮、山药、丹皮、独活、川牛膝、杜仲、狗脊、伸筋草、白芍、生白术、红花、砂仁、莪术、甘草十七味药混合研磨成细粉；然后将各种药粉混合均匀后装入胶囊即为成品药，胶囊内所述的各组分的药物均为细度为80目的粉状混合物。每粒胶囊装入药粉0.3g，其制备胶囊993.3粒。
口服量为每次3g，每日服用2次。
《临床试验例》:
1、 一般情况：
门诊选择腰椎间盘突出症330例，男210例、女120例；年龄：30—70岁；平均年龄45.3岁，病程6天至12年其中L4-5突出者113例，L5-S1突出者190，L43-4加L4-5加L5-S1突出者7例，突出属中央型者42例属左旁侧型128例，右属左旁侧型，118例，轻度膨出者22例，所有病例均有腰腿痛症状你，至少一侧下肢直腿抬高试验阳性，且经CT或MRI确诊。
排除标准：排除：①不符合腰椎间盘突出症诊断者，如腰椎椎管狭窄症，马尾肿瘤，腰椎滑脱等疾病所致的腰腿痛；②反复发作患者，如处于缓解期，腰腿痛不明显者；③怀孕期、有严重高血压、脑血管疾病、心脏疾病患者。
2、 诊断标准：依据《中医病证诊断疗效标准》制定诊断标准。
纳入标准：纳入：①符合中医腰腿痛或痹证诊断，西医诊断为腰椎间盘突出症者；②所有患者均经腰椎间盘CT或MRI扫描确诊为腰椎间盘突出；③年龄在30—70岁之间者。
3、治疗方法：
本发明胶囊0.3g/粒，每日二次，口服量为每次3g（即10粒）。四周为一个疗程。观察期间停用一切药物，并禁服浓茶、绿豆汤，减少豆类食物的摄入，同时查血、尿常规及肝功，第四周结束后复查以上指标。
4、疗效判断标准：
疗效标准参照《中医病证诊断疗效标准》制定。痊愈：症状与体征消失，腰椎旁无压痛及放射痛，直腿抬高70度以上，腰腿活动自如，功能正常，恢复正常工作；显效：腰腿症状活动明显减轻，腰部活动明显改善，直腿抬高50～70度；有效：腰腿症状有所减轻，腰部活动改善，可做一般工作；无效：腰腿症状体征无改善。
5、疗效观察：
治疗组：服用上述治疗腰椎间盘突出症胶囊每次3g，一日两次，饭后服。注意事项：减少久坐、负重，适当运动。
对照组：西医对症治疗，氯唑沙宗片0.4g，一日三次，饭后服；芬必得胶囊0.3g，一日两次，饭后服；维生素B1片10mg，一日三次；甲钴胺片0.5g，一日三次，饭后服；有慢性胃炎及溃疡患者给予奥美拉唑胶囊20mg，一日两次，饭前半小时服。注意事项：急性期卧硬板床休息两周。
两组临床比较见表1：
从表1中可以看出：腰椎间盘突出症胶囊痊愈率82%，有效率93%，明显优于对照组，且副作用少。
⑵ 复发率：临床治愈74例，随访问6个月，复发9例，再次服药仍有效。
⑵ 不良反应：服药期间有4例自觉全身瘙痒，见散在皮疹，停药后恢复；有3例服药后出现上腹部不适，减量或给予雷尼替丁胶囊0.15g、每日一次、饭前服后，上腹不适症状消失；有2例因服药过量出现口唇发麻、肢体僵硬，经服用甘草水后症状消失，按常规量服用后未出现以上症状。166例患者治疗前后血、尿常规及肝功检查未见异常变化。

Claims (3)

1.一种治疗腰椎间盘突出症的药物，其特征在于它由下述重量份的原料制成：
熟地20-30份、枣皮15-20份、山药20-30份、丹皮12-15份、茯苓12-15份、泽泻12-15份、独活12-15份、川牛膝12-15份、杜仲12-15份、制马钱子12-15份、狗脊12-15份、地龙12-15份、伸筋草12-15份、炮山甲8-10份、土元12-15份、白芍15-20份、生白术12-15份、红花10-12份、砂仁12-15份、莪术12-15份、甘草6-8份。
2.根据权利要求1所述的一种治疗腰椎间盘突出症的药物，其特征在于它由下述重量份的原料制成：
熟地30份、枣皮20份、山药30份、丹皮15份、茯苓15份、泽泻15份、独活15份、川牛膝15份、杜仲15份、制马钱子15份、狗脊15份、地龙15份、伸筋草15份、炮山甲10份、土元15份、白芍20份、生白术15份、红花12份、砂仁15份、莪术15份、甘草8份。
3.根据权利要求1或2所述的一种治疗腰椎间盘突出症的药物，其特征在于：其剂型为胶囊，制备方法是 ：将制马钱子、炮山甲、地龙、土元分别研磨成细粉，将茯苓、泽泻、熟地、枣皮、山药、丹皮、独活、川牛膝、杜仲、狗脊、伸筋草、白芍、生白术、红花、砂仁、莪术、甘草十七味药混合研磨成细粉，胶囊内各组分的药物均为细度不低于80目的粉状混合物。
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1196264A (zh) * 1998-05-12 1998-10-21 孙全凯 壮腰固脱丸
CN101342293A (zh) * 2008-09-04 2009-01-14 何茁 壮腰益肾中药制剂
CN103550469A (zh) * 2013-11-13 2014-02-05 王跃东 一种治疗腰痛病症的中药组合物

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1196264A (zh) * 1998-05-12 1998-10-21 孙全凯 壮腰固脱丸
CN101342293A (zh) * 2008-09-04 2009-01-14 何茁 壮腰益肾中药制剂
CN103550469A (zh) * 2013-11-13 2014-02-05 王跃东 一种治疗腰痛病症的中药组合物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
综合疗法治疗腰椎间盘突出症76例;王少伟等;《新中医》;20010228;第33卷(第2期);第51-52页 *
马钱子合独活寄生汤治疗腰椎间盘突出症180例;俞强;《浙江中医杂志》;20050625;第246页 *

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