CN104367681A - 一种治疗灰指甲的中西药复合滴剂及其制备方法 - Google Patents

一种治疗灰指甲的中西药复合滴剂及其制备方法 Download PDF

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CN104367681A
CN104367681A CN201410653488.8A CN201410653488A CN104367681A CN 104367681 A CN104367681 A CN 104367681A CN 201410653488 A CN201410653488 A CN 201410653488A CN 104367681 A CN104367681 A CN 104367681A
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itraconazole
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张庆吉
王爱实
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    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
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    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
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    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A—HUMAN NECESSITIES
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

本发明公开了一种治疗灰指甲的中西药复合滴剂及其制备方法，属于灰指甲药物领域，用于灰指甲治疗，其包括苦参10~20g，五倍子3~12g，蒲公英5~10g，黄柏5~10g，明矾2~5g，伊曲康唑10~15mg，凡士林10~15g，甘草2~5g，虎杖2~5g，并通过将中草药进行两次煎煮，分别过滤药液后进行混合浓缩，将浓缩后的药液加入伊曲康唑10~15mg，凡士林10~15g后灭菌进行装瓶。鉴于上述技术方案，本发明能够不对皮肤产生刺激、效果显著，且使用浓度低，见效快，不会对周围环境产生污染。

Description

一种治疗灰指甲的中西药复合滴剂及其制备方法
技术领域
本发明属于灰指甲药物，具体地说，尤其涉及一种治疗灰指甲的中西药复合滴剂及其制备方法。
背景技术
“灰指甲”病属于一种常见的真菌性疾病，当人们的手指甲或脚趾甲变成灰白色，人们通常称之为“灰指甲”。通常，灰指甲亦称甲癣，最常见的为灰白色或褐色和深褐色。同时可见到甲板增厚、变脆，或甲板中层蛀空，或甲缘参差不齐，或甲板残缺不全等。有的还可伴有甲沟发炎，局部红肿疼痛。已有治疗灰指甲品种很多，抗菌性能不一，有高、中、低效之分。往往是高效灰指药物的有效浓度高，成本价格也高，稳定性差，有毒性、腐蚀性、刺激性气味，对皮肤有一定的损伤，对环境也有一定的污染，效果差。
发明内容
本发明的目的在于提供一种治疗灰指甲的中西药复合滴剂及其制备方法，其能够不对皮肤产生刺激、效果显著，且使用浓度低，见效快，不会对周围环境产生污染。
本发明是通过以下技术方案实现的：
一种治疗灰指甲的中西药复合滴剂，由以下重量成份组成：
苦参10~20g，五倍子3~12g，蒲公英5~10g，黄柏5~10g，明矾2~5g，伊曲康唑10~15mg，凡士林10~15g，甘草2~5g，虎杖2~5g。
一种治疗灰指甲的药剂的制作方法，其制作方法是：
步骤一、将苦参10~20g，五倍子3~12g，蒲公英5~10g，黄柏5~10g，明矾2~5g，甘草2~5g，虎杖2~5g按照重量份称取后，切碎，并置于1：5的蒸馏水中进行煎煮，煎煮时间为30~60min；
步骤二、将上述煎煮完成的药液进行过滤，再加入1：4的蒸馏水进行煎煮，煎煮时间为25~40min，并过滤药液，与第一次煎煮的药液进行混合；
步骤三、将混合后的药液进行浓缩，浓缩后加入伊曲康唑10~15mg，凡士林10~15g，搅拌均匀后装瓶。
与现有技术相比，本发明具有以下的有益效果：本发明具有较低的使用浓度，不会对周围的环境和皮肤造成刺激，且治疗效果显著，适用于各个年龄段的患者，对不同的皮肤和类型的灰指甲具有良好的治愈效果。
具体实施方式
为更好地说明本发明的有益效果，下面结合具体实施例进行详细地介绍。
实施例1：一种治疗灰指甲的中西药复合滴剂，其特征在于，由以下重量成份组成：
苦参10g，五倍子3g，蒲公英5g，黄柏5g，明矾2g，伊曲康唑10mg，凡士林10g，甘草2g，虎杖2g。
一种治疗灰指甲的药剂的制作方法，其制作方法是：
步骤一、将苦参10g，五倍子3g，蒲公英5g，黄柏5g，明矾2g，甘草2g，虎杖2g按照重量份称取后，切碎，并置于1：5的蒸馏水中进行煎煮，煎煮时间为30min；
步骤二、将上述煎煮完成的药液进行过滤，再加入1：4的蒸馏水进行煎煮，煎煮时间为25min，并过滤药液，与第一次煎煮的药液进行混合；
步骤三、将混合后的药液进行浓缩，浓缩后加入伊曲康唑10mg，凡士林10g，搅拌均匀后装瓶。
实施例2：一种治疗灰指甲的中西药复合滴剂，其特征在于，由以下重量成份组成：
苦参20g，五倍子12g，蒲公英10g，黄柏10g，明矾5g，伊曲康唑15mg，凡士林15g，甘草5g，虎杖5g。
2、如权利要求1所述的一种治疗灰指甲的药剂的制作方法，其特征在于其制作方法是：
步骤一、将苦参20g，五倍子12g，蒲公英10g，黄柏10g，明矾5g，甘草5g，虎杖5g按照重量份称取后，切碎，并置于1：5的蒸馏水中进行煎煮，煎煮时间为60min；
步骤二、将上述煎煮完成的药液进行过滤，再加入1：4的蒸馏水进行煎煮，煎煮时间为40min，并过滤药液，与第一次煎煮的药液进行混合；
步骤三、将混合后的药液进行浓缩，浓缩后加入伊曲康唑15mg，凡士林15g，搅拌均匀后装瓶。

Claims (2)

1.一种治疗灰指甲的中西药复合滴剂，其特征在于，由以下重量成份组成：
苦参10~20g，五倍子3~12g，蒲公英5~10g，黄柏5~10g，明矾2~5g，伊曲康唑10~15mg，凡士林10~15g，甘草2~5g，虎杖2~5g。
2.根据权利要求1所述的一种治疗灰指甲的药剂的制作方法，其特征在于其制作方法是：
步骤一、将苦参10~20g，五倍子3~12g，蒲公英5~10g，黄柏5~10g，明矾2~5g，甘草2~5g，虎杖2~5g按照重量份称取后，切碎，并置于1：5的蒸馏水中进行煎煮，煎煮时间为30~60min；
步骤二、将上述煎煮完成的药液进行过滤，再加入1：4的蒸馏水进行煎煮，煎煮时间为25~40min，并过滤药液，与第一次煎煮的药液进行混合；
步骤三、将混合后的药液进行浓缩，浓缩后加入伊曲康唑10~15mg，凡士林10~15g，搅拌均匀后装瓶。
CN201410653488.8A 2014-11-18 2014-11-18 一种治疗灰指甲的中西药复合滴剂及其制备方法 Pending CN104367681A (zh)

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CN109646487A (zh) * 2019-01-24 2019-04-19 河北农业大学 一种治疗兔皮肤真菌病的药物添加剂及其制备方法

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Cited By (2)

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CN109646487A (zh) * 2019-01-24 2019-04-19 河北农业大学 一种治疗兔皮肤真菌病的药物添加剂及其制备方法
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