CN104367663A - Plaster for treating soft tissue injury and production method thereof - Google Patents
Plaster for treating soft tissue injury and production method thereof Download PDFInfo
- Publication number
- CN104367663A CN104367663A CN201410613462.0A CN201410613462A CN104367663A CN 104367663 A CN104367663 A CN 104367663A CN 201410613462 A CN201410613462 A CN 201410613462A CN 104367663 A CN104367663 A CN 104367663A
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- Prior art keywords
- plaster
- rubber
- vaseline
- zinc oxide
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to the field of medicines, and particularly relates to a plaster for treating soft tissue injury. The plaster is prepared from cape jasmine, menthol, borneol, rubber, zinc oxide, rosin, vaseline and lanolin. The production method comprises the following steps: grinding the cape jasmine in the formula amount into coarse powder; percolating at a speed of 2-3ml/min*kg according to a percolation method under the items of fluid extract and extract by using 70% ethanol which is seven times of the amount of the cape jasmine as a solvent, collecting percolation liquid, and preparing fluid extract for later use; crushing rubber in the formula amount, adding the crushed rubber into a plaster making drum filled with gasoline, uniformly stirring, and sealing and soaking for 12-24 hours; respectively sequentially adding vaseline and lanolin in the formula amount, and stirring for 30 minutes; adding zinc oxide and rosin, stirring for 2 hours, and uniformly sufficiently stirring to prepare matrix; adding the fluid extract, menthol and borneol, stirring for 1 hour, and uniformly stirring to obtain plaster slurry; filtering, coating, cutting into sections, covering a lining, and slicing. The pain-relieving plaster has remarkable effect of relieving and easing pain, is quick in response, and has low production cost.
Description
Technical field
The present invention relates to field of medicaments, especially a kind of plaster and production method thereof for the treatment of soft tissue injury.
Background technology
The existing product category on the market for pain relieving is more, and have plaster class, also have baste class, all have the effects such as certain pain relieving, analgesia, detumescence, but its curative effect is slow, the course for the treatment of is long, effect is relatively poor; Simultaneously poorer for the therapeutic effect of acute closed property soft tissue sprain, contusion.
Summary of the invention
The object of the invention is the deficiency in order to solve above-mentioned technology and provide one to have promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain, being applicable to acute closed property soft tissue sprain, the auxiliary treatment of contusion and the plaster of the good treatment soft tissue injury of therapeutic effect and production method thereof.
In order to achieve the above object, the plaster of the treatment soft tissue injury designed by the present invention, it is made up of Fructus Gardeniae, Mentholum, Borneolum Syntheticum, rubber, zinc oxide, Colophonium, vaseline, lanoline, and wherein rubber, zinc oxide, Colophonium, vaseline and lanoline are adjuvant; Mass fraction shared by each composition is: Fructus Gardeniae 500-550 part, Mentholum 15-25 part, Borneolum Syntheticum 10-20 part, rubber 150-200 part, zinc oxide 150-200 part, Colophonium 150-200 part, vaseline 30-40 part, lanoline 20-30 part.
The production method of the plaster for the treatment of soft tissue injury, the gardenia powder of formula ratio is broken into coarse powder, ethanol with 70% of Fructus Gardeniae seven times amount is as solvent, according to the percolation under fluid extract and extractum item, percolation is carried out with 2-3 ml/min * kilogram speed, and collect percolate, make fluid extract for subsequent use; Get the rubber grating of formula ratio, add and add beating in cream bucket of gasoline and stir, airtight immersion 12-24 hour, the vaseline and the lanoline that add formula ratio respectively successively stir 30 minutes, add zinc oxide again, Colophonium stirs 2 hours, stir, make substrate; Then add fluid extract, Mentholum, Borneolum Syntheticum stir 1 hour, stir evenly into cream slurry, then filter, Tu cream, cutting, lid lining, cuts into slices.
The plaster of the treatment soft tissue injury that the present invention obtains and production method thereof, the application of the ZHITONG GAO obtained in clinical trial; Acute and closed soft tissue injury 1328 example, result: swelled and ache within 3 days disappearance person 1068 example, for sprained ankle medication treatment 40 example, can all cure for average 3 days.So its pain relieving, analgesic effect are obvious, instant effect; And production cost is low.
Detailed description of the invention
The present invention is further described by the following embodiment.
Embodiment 1:
The plaster of the treatment soft tissue injury that the present embodiment describes, it is made up of Fructus Gardeniae, Mentholum, Borneolum Syntheticum, rubber, zinc oxide, Colophonium, vaseline, lanoline, and wherein rubber, zinc oxide, Colophonium, vaseline and lanoline are adjuvant; Mass fraction shared by each composition is: Fructus Gardeniae 535 parts, Mentholum 20 parts, Borneolum Syntheticum 15 parts, rubber 170 parts, zinc oxide 185 parts, Colophonium 160 parts, 35 parts, vaseline, lanoline 25 parts.
535g gardenia powder is broken into coarse powder by the production method of the plaster for the treatment of soft tissue injury, ethanol with 70% of Fructus Gardeniae seven times amount, as solvent, according to the percolation under fluid extract and extractum item, carries out percolation with 2-3 ml/min * kilogram speed, and collect percolate, make fluid extract for subsequent use; Get the grating of 170g rubber, add and add beating in cream bucket of gasoline and stir, airtight immersion 18 hours, add 35g vaseline successively respectively and 25g lanoline stirs 30 minutes, add zinc oxide 185g again, Colophonium 160g stirs 2 hours, stir, make substrate; Then add above-mentioned fluid extract, Mentholum 20g, Borneolum Syntheticum 15g stir 1 hour, stir evenly into cream slurry, then filter, Tu cream, cutting, lid lining, cuts into slices.
Embodiment 2:
The plaster of the treatment soft tissue injury that the present embodiment describes, it is made up of Fructus Gardeniae, Mentholum, Borneolum Syntheticum, rubber, zinc oxide, Colophonium, vaseline, lanoline, and wherein rubber, zinc oxide, Colophonium, vaseline and lanoline are adjuvant; Mass fraction shared by each composition is: Fructus Gardeniae 500 parts, Mentholum 15 parts, Borneolum Syntheticum 10 parts, rubber 150 parts, zinc oxide 150 parts, Colophonium 150 parts, 30 parts, vaseline, lanoline 20 parts.
Embodiment 3:
The plaster of the treatment soft tissue injury that the present embodiment describes, it is made up of Fructus Gardeniae, Mentholum, Borneolum Syntheticum, rubber, zinc oxide, Colophonium, vaseline, lanoline, and wherein rubber, zinc oxide, Colophonium, vaseline and lanoline are adjuvant; Mass fraction shared by each composition is: Fructus Gardeniae 550 parts, Mentholum 25 parts, Borneolum Syntheticum 20 parts, rubber 200 parts, zinc oxide 200 parts, Colophonium 200 parts, 40 parts, vaseline, lanoline 30 parts.
Claims (2)
1. treat a plaster for soft tissue injury, it is characterized in that: it is made up of Fructus Gardeniae, Mentholum, Borneolum Syntheticum, rubber, zinc oxide, Colophonium, vaseline, lanoline, wherein rubber, zinc oxide, Colophonium, vaseline and lanoline are adjuvant; Mass fraction shared by each composition is: Fructus Gardeniae 500-550 part, Mentholum 15-25 part, Borneolum Syntheticum 10-20 part, rubber 150-200 part, zinc oxide 150-200 part, Colophonium 150-200 part, vaseline 30-40 part, lanoline 20-30 part.
2. treat the production method of the plaster of soft tissue injury for one kind, it is characterized in that: the gardenia powder of formula ratio is broken into coarse powder, ethanol with 70% of Fructus Gardeniae seven times amount is as solvent, according to the percolation under fluid extract and extractum item, percolation is carried out with 2-3 ml/min * kilogram speed, and collect percolate, make fluid extract for subsequent use; Get the rubber grating of formula ratio, add and add beating in cream bucket of gasoline and stir, airtight immersion 12-24 hour, the vaseline and the lanoline that add formula ratio respectively successively stir 30 minutes, add zinc oxide again, Colophonium stirs 2 hours, stir, make substrate; Then add fluid extract, Mentholum, Borneolum Syntheticum stir 1 hour, stir evenly into cream slurry, then filter, Tu cream, cutting, lid lining, cuts into slices.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410613462.0A CN104367663A (en) | 2014-11-05 | 2014-11-05 | Plaster for treating soft tissue injury and production method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410613462.0A CN104367663A (en) | 2014-11-05 | 2014-11-05 | Plaster for treating soft tissue injury and production method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104367663A true CN104367663A (en) | 2015-02-25 |
Family
ID=52547024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410613462.0A Pending CN104367663A (en) | 2014-11-05 | 2014-11-05 | Plaster for treating soft tissue injury and production method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104367663A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107375891A (en) * | 2017-08-17 | 2017-11-24 | 杭州仁德医药有限公司 | A kind of preparation method of external plaster for wind-damp dispelling |
| CN107412286A (en) * | 2017-06-26 | 2017-12-01 | 杭州仁德医药有限公司 | A kind of preparation method for being used to treat arthralgic external plaster |
| CN110403988A (en) * | 2019-09-05 | 2019-11-05 | 杭州市西溪医院 | A kind of traditional Chinese herb medicine and preparation method thereof with external application function of promoting blood circulation to disperse blood clots |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04308527A (en) * | 1991-04-05 | 1992-10-30 | Sekisui Chem Co Ltd | Plaster for medical use |
| CN102824452A (en) * | 2012-09-25 | 2012-12-19 | 吕秀兰 | Pain relieving fitness paste and production method thereof |
-
2014
- 2014-11-05 CN CN201410613462.0A patent/CN104367663A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04308527A (en) * | 1991-04-05 | 1992-10-30 | Sekisui Chem Co Ltd | Plaster for medical use |
| CN102824452A (en) * | 2012-09-25 | 2012-12-19 | 吕秀兰 | Pain relieving fitness paste and production method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 薛慧中等: "栀子治伤膏的制备工艺与质量标准研究", 《南京中医药大学学报》 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107412286A (en) * | 2017-06-26 | 2017-12-01 | 杭州仁德医药有限公司 | A kind of preparation method for being used to treat arthralgic external plaster |
| CN107412286B (en) * | 2017-06-26 | 2021-05-25 | 杭州仁德医药有限公司 | Preparation method of external plaster for treating arthralgia |
| CN107375891A (en) * | 2017-08-17 | 2017-11-24 | 杭州仁德医药有限公司 | A kind of preparation method of external plaster for wind-damp dispelling |
| CN107375891B (en) * | 2017-08-17 | 2021-05-04 | 杭州仁德医药有限公司 | Preparation method of external plaster for expelling wind-damp |
| CN110403988A (en) * | 2019-09-05 | 2019-11-05 | 杭州市西溪医院 | A kind of traditional Chinese herb medicine and preparation method thereof with external application function of promoting blood circulation to disperse blood clots |
| CN110403988B (en) * | 2019-09-05 | 2021-11-30 | 杭州市西溪医院 | A Chinese medicinal ointment with effects of promoting blood circulation and removing blood stasis, and its preparation method |
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| PB01 | Publication | ||
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150225 |
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| WD01 | Invention patent application deemed withdrawn after publication |