CN102119945A - Method for preparing ultrasonic extracted Chinese medicinal preparation for treating qi deficiency - Google Patents
Method for preparing ultrasonic extracted Chinese medicinal preparation for treating qi deficiency Download PDFInfo
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- CN102119945A CN102119945A CN 201110051260 CN201110051260A CN102119945A CN 102119945 A CN102119945 A CN 102119945A CN 201110051260 CN201110051260 CN 201110051260 CN 201110051260 A CN201110051260 A CN 201110051260A CN 102119945 A CN102119945 A CN 102119945A
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Abstract
The invention discloses a method for preparing an ultrasonic extracted Chinese medicinal preparation for treating qi deficiency, which belongs to the technical field of traditional Chinese medicaments. The method comprises the following steps of: crushing ginseng into coarse powder, putting the coarse powder into an ultrasonic extractor, adding 30 percent ethanol in an amount which is 3 times weight of the coarse powder, starting ultrasonic equipment at a temperature of between 20 and 25 DEG C, performing ultrasonic treatment for 40 minutes, filtering, reclaiming the ethanol, concentrating the filtrate to original amount, adding the ethanol in an amount which is 3 times weight of the concentrate, stirring, standing, taking the supernate, reclaiming the ethanol, and concentrating the supernate to 100ml; and adding sodium benzoate, stirring the solution uniformly, regulating the ethanol content to be 20 to 30 percent, standing at a temperature of between 5 and 10 DEG C, taking the supernate, filtering the supernate, adding water till 1,000ml, standing for 7 days at a temperature of between 5 and 10 DEG C, taking the supernate, filtering the supernate, and packing the supernate to obtain the preparation. By adopting the advanced ultrasonic extraction technology, the effective ingredients based on ginsenoside in the preparation are obviously improved, the quality and the curative effect of the medicament are improved, the clinical effect of the preparation is improved, the yield and the purity of the product are improved, the cost is saved, and the method is suitable for large-scale production operation.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of preparation method for the treatment of the ultrasonic extraction Chinese medicine preparation of deficiency of vital energy disease.
Background technology
In the prior art, a lot of mixture products of circulation on the market, but many employings is that traditional handicraft is extracted, decoct with water, in the process that decocts, the active substance that decomposes can lose easily, and the medical material surface can produce the gelatinizing phenomenon, and the inner active ingredient of medical material can not discharge fully.Therefore, making full use of medical material, improve the preparation curative effect, cut down the consumption of energy, is the problem that each enterprise will capture.As ginseng oral liquid (Bureau of Drugs Supervision's standard: WS-1148 (ZD-1488)-2002), it is as follows to write out a prescription: Radix Ginseng 100g, sodium benzoate 3g.Method for making: the Radix Ginseng powder is broken into coarse powder, adds 30% alcohol dipping 72 hours, according to percolation (appendix IO of Chinese Pharmacopoeia version in 2000) percolation.Collect percolate, reclaim ethanol, be concentrated into primary dose, it is an amount of to add ethanol, stir, leave standstill, get supernatant, reclaim ethanol, be concentrated in right amount, add sodium benzoate, stir well, it is 20%～25% that adjusting contains the alcohol amount, leave standstill in 5～10 ℃, get supernatant, filter, add water to ormal weight, left standstill 7 days in 5～10 ℃, get supernatant, filter, packing, promptly.
Summary of the invention
The objective of the invention is provides a kind of advanced ultrasonic wave extraction that adopts at above-mentioned deficiency, makes steady quality, the raising curative effect of mixture, the preparation method of the ultrasonic extraction Chinese medicine preparation of the treatment deficiency of vital energy disease that cuts down the consumption of energy.
The technology of the present invention solution is: the preparation method of the ultrasonic extraction Chinese medicine preparation of treatment deficiency of vital energy disease, may further comprise the steps: (1) raw material: the prescription of pressing ginseng oral liquid (Bureau of Drugs Supervision's standard: WS-1148 (ZD-1488)-2002): Radix Ginseng 100g, sodium benzoate 3g; (2) Radix Ginseng powder is broken into coarse powder (40 order), puts into the ultrasonic extraction device, add 3 times of amount 30% ethanol, 20～25 ℃ of temperature, (make a leapleap forward in Shanghai, 50hz to start ultrasonic equipment, 250kw), ultrasonic 40min filters, reclaim ethanol, be concentrated into primary dose, add 3 times of amount ethanol and stir, leave standstill, get supernatant, reclaim ethanol, be concentrated into 100ml; (3) add sodium benzoate, stir, regulate the alcohol amount 20%～30% that contains, leave standstill in 5～10 ℃, get supernatant, filter, add water to 1000ml, left standstill 7 days in 5～10 ℃, get supernatant, filter, packing, promptly.Dosage form is a mixture.
Advantage of the present invention is: 1, adopted the advanced ultrasound extractive technique, overcome traditional extraction technique can not propose fully active substance in the medical material shortcoming, active ingredient in the preparation has improved drug quality and curative effect in the obvious raising of ginsenoside, has improved the clinical effectiveness of preparation.Advantages such as 2, extraction time is short, yield is high, need not heating, the ethanol consumption is few have been simplified operation sequence greatly, have been shortened extraction time, have improved product yield and purity, save cost, are fit to big production operation.
Ginsenoside Re's content (in preparation) in the table 1 same frequency different time extracting solution
Ginsenoside Re's content (in preparation) in the table 2 alcohol percolation method extracting solution
Below in conjunction with embodiment embodiments of the present invention are described in further detail.
The specific embodiment
Embodiment
The preparation method of the ultrasonic extraction Chinese medicine preparation of treatment deficiency of vital energy disease: raw material: get Radix Ginseng 100g, sodium benzoate 3g is standby.Preparation method: 1, the Radix Ginseng powder is broken into coarse powder (40 order), puts into the ultrasonic extraction device, add 3 times of amount 30% ethanol, 20～25 ℃ of temperature, (make a leapleap forward in Shanghai, 50hz to start ultrasonic equipment, 250kw), ultrasonic 40min filters, reclaim ethanol, be concentrated into primary dose, add 3 times of amount ethanol and stir, leave standstill, get supernatant, reclaim ethanol, be concentrated into 100ml; 2, add sodium benzoate, stir, regulate the alcohol amount 20%～30% that contains, leave standstill in 5～10 ℃, get supernatant, filter, add water to 1000ml, left standstill 7 days in 5～10 ℃, get supernatant, filter, packing, promptly.
Claims (2)
1. preparation method for the treatment of the ultrasonic extraction Chinese medicine preparation of deficiency of vital energy disease may further comprise the steps:
(1) raw material: Radix Ginseng 100g, sodium benzoate 3g;
(2) Radix Ginseng powder is broken into coarse powder, puts into the ultrasonic extraction device, add 3 times of amount 30% ethanol, 20～25 ℃ of temperature start ultrasonic equipment, ultrasonic 40min filters, and reclaims ethanol, is concentrated into primary dose, adds 3 times of amount ethanol and stirs, leave standstill, get supernatant, reclaim ethanol, be concentrated into 100ml;
(3) add sodium benzoate, stir, regulate the alcohol amount 20%～30% that contains, leave standstill in 5～10 ℃, get supernatant, filter, add water to 1000ml, left standstill 7 days in 5～10 ℃, get supernatant, filter, packing, promptly;
2. the preparation method of the ultrasonic extraction Chinese medicine preparation of treatment deficiency of vital energy disease according to claim 1 is characterized in that mixture.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110051260 CN102119945A (en) | 2011-03-04 | 2011-03-04 | Method for preparing ultrasonic extracted Chinese medicinal preparation for treating qi deficiency |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110051260 CN102119945A (en) | 2011-03-04 | 2011-03-04 | Method for preparing ultrasonic extracted Chinese medicinal preparation for treating qi deficiency |
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| Publication Number | Publication Date |
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| CN102119945A true CN102119945A (en) | 2011-07-13 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN 201110051260 Pending CN102119945A (en) | 2011-03-04 | 2011-03-04 | Method for preparing ultrasonic extracted Chinese medicinal preparation for treating qi deficiency |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106720378A (en) * | 2016-12-05 | 2017-05-31 | 吉林大学 | A kind of preparation method of panaxan's Yoghourt blueberry chewable tablet |
| CN112011431A (en) * | 2020-09-14 | 2020-12-01 | 劲牌持正堂药业有限公司 | Preparation and application of ginseng extract with good stability |
-
2011
- 2011-03-04 CN CN 201110051260 patent/CN102119945A/en active Pending
Non-Patent Citations (2)
| Title |
|---|
| 《卫生部颁药品标准》 20021231 国家药典委员会 人参口服液 242 1-2 , 1 * |
| 《自然杂志》 20011030 项昭保等 超声波在中草药化学成分提取中的应用 289-291 1-2 第23卷, 第5期 2 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106720378A (en) * | 2016-12-05 | 2017-05-31 | 吉林大学 | A kind of preparation method of panaxan's Yoghourt blueberry chewable tablet |
| CN112011431A (en) * | 2020-09-14 | 2020-12-01 | 劲牌持正堂药业有限公司 | Preparation and application of ginseng extract with good stability |
| CN112011431B (en) * | 2020-09-14 | 2023-01-17 | 劲牌持正堂药业有限公司 | Preparation and application of ginseng extract with good stability |
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Application publication date: 20110713 |