CN104364393A - 用于诊断和治疗广泛性发育障碍的组合物和方法 - Google Patents
用于诊断和治疗广泛性发育障碍的组合物和方法 Download PDFInfo
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- CN104364393A CN104364393A CN201380022420.3A CN201380022420A CN104364393A CN 104364393 A CN104364393 A CN 104364393A CN 201380022420 A CN201380022420 A CN 201380022420A CN 104364393 A CN104364393 A CN 104364393A
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- pervasive developmental
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- developmental disorders
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
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- G—PHYSICS
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A61K38/44—Oxidoreductases (1)
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
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- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/51—Complete heavy chain or Fd fragment, i.e. VH + CH1
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
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- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
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- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
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- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
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- G01N2800/56—Staging of a disease; Further complications associated with the disease
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pathology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Marine Sciences & Fisheries (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261606935P | 2012-03-05 | 2012-03-05 | |
| US61/606,935 | 2012-03-05 | ||
| PCT/US2013/029201 WO2013134315A1 (en) | 2012-03-05 | 2013-03-05 | Compositions and methods for diagnosis and treatment of pervasive developmental disorder |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104364393A true CN104364393A (zh) | 2015-02-18 |
Family
ID=49117277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380022420.3A Pending CN104364393A (zh) | 2012-03-05 | 2013-03-05 | 用于诊断和治疗广泛性发育障碍的组合物和方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US20150023949A1 (enExample) |
| EP (1) | EP2823063A4 (enExample) |
| JP (3) | JP2015517801A (enExample) |
| KR (1) | KR20140140069A (enExample) |
| CN (1) | CN104364393A (enExample) |
| AU (1) | AU2013230045A1 (enExample) |
| CA (1) | CA2866407A1 (enExample) |
| HK (1) | HK1206393A1 (enExample) |
| WO (1) | WO2013134315A1 (enExample) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106714556A (zh) * | 2014-04-11 | 2017-05-24 | 美国控股实验室公司 | 用于测定自闭症谱系病症风险的方法和系统 |
| CN106885858A (zh) * | 2017-03-10 | 2017-06-23 | 方雷 | 一种高效的痕量临床病人样本的高通量全蛋白组学定量分析方法 |
| CN107312846A (zh) * | 2017-07-12 | 2017-11-03 | 北京赛尔维康生物医学科技有限公司 | Capg和ptgis基因在制备脊柱侧弯检测试剂盒中的应用 |
| CN109212226A (zh) * | 2018-09-06 | 2019-01-15 | 中国人民解放军兰州军区兰州总医院 | 预测急性高山病发病风险的血浆蛋白标志物及其在制备诊断ams易感性试剂盒中的应用 |
| CN109239334A (zh) * | 2018-09-10 | 2019-01-18 | 吉林大学 | 建立时间分辨荧光免疫层析法检测MxA试剂盒 |
| CN112442527A (zh) * | 2019-08-27 | 2021-03-05 | 深圳市英马诺生物科技有限公司 | 孤独症诊断试剂盒、基因芯片、基因靶点筛选方法及应用 |
| CN114470009A (zh) * | 2015-05-22 | 2022-05-13 | 亚利桑那大学董事会 | 用于治疗自闭症谱系障碍及相关症状的方法 |
| US11674948B2 (en) | 2014-04-11 | 2023-06-13 | Laboratory Corporation Of America Holdings | Methods and systems for determining autism spectrum disorder risk |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104520435A (zh) | 2012-04-02 | 2015-04-15 | 博格有限责任公司 | 基于细胞的探询式分析及其应用 |
| WO2015191783A2 (en) | 2014-06-10 | 2015-12-17 | Abbvie Inc. | Biomarkers for inflammatory disease and methods of using same |
| WO2016040725A1 (en) | 2014-09-11 | 2016-03-17 | Berg Llc | Bayesian causal relationship network models for healthcare diagnosis and treatment based on patient data |
| EP3440705A4 (en) | 2016-04-01 | 2019-11-13 | INTEL Corporation | TRANSISTOR CELLS WITH A DEEP CONTACT WITH CLADDING OF DIELECTRIC MATERIAL |
| US10650621B1 (en) | 2016-09-13 | 2020-05-12 | Iocurrents, Inc. | Interfacing with a vehicular controller area network |
| US11216742B2 (en) | 2019-03-04 | 2022-01-04 | Iocurrents, Inc. | Data compression and communication using machine learning |
| WO2020215043A1 (en) * | 2019-04-19 | 2020-10-22 | Yale University | Advanced glycation end-product breaking biocatalysts |
| KR102158009B1 (ko) * | 2019-06-13 | 2020-09-21 | 고려대학교 산학협력단 | 주의력 결핍/과잉행동장애 진단용 마커로서의 14-3-3γ의 용도 |
| CN118019982A (zh) * | 2021-05-25 | 2024-05-10 | 耶路撒冷希伯来大学伊萨姆研发有限公司 | 通过多组学平台诊断孤独症谱系障碍 |
| TWI866002B (zh) * | 2021-12-29 | 2024-12-11 | 財團法人生物技術開發中心 | 反義寡核苷酸及其用途 |
| ES2976116A1 (es) * | 2023-12-15 | 2024-07-23 | Chrmtx Sl | Biomarcadores nucleares de la enfermedad de Alzheimer (EA), sus usos y métodos |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7396654B2 (en) * | 2004-04-15 | 2008-07-08 | University Of Florida Research Foundation, Inc. | Neural proteins as biomarkers for traumatic brain injury |
| GB0419124D0 (en) * | 2004-08-27 | 2004-09-29 | Proteome Sciences Plc | Methods and compositions relating to Alzheimer's disease |
| CN101194260A (zh) * | 2005-01-24 | 2008-06-04 | 利兰·斯坦福青年大学托管委员会 | 使用贝叶斯网络建立细胞信号传导系统模型的方法 |
| EP1840574A1 (en) * | 2006-03-30 | 2007-10-03 | Institut Pasteur | Use of the alpha chain of brain spectrin and fragments thereof, for diagnosing cerebral diseases |
| US20090117562A1 (en) * | 2007-04-09 | 2009-05-07 | Valerie Wailin Hu | Method and kit for diagnosing Autism using gene expression profiling |
| JP6078211B2 (ja) * | 2008-02-20 | 2017-02-15 | ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアThe Children’S Hospital Of Philadelphia | 自閉症および自閉症の表現型に関連する遺伝子変化ならびに自閉症の診断および治療に対するその使用方法 |
| US8173369B2 (en) * | 2008-05-15 | 2012-05-08 | The Regents Of The University Of California | Peripheral gene expression biomarkers for autism |
| WO2010056982A2 (en) * | 2008-11-17 | 2010-05-20 | The George Washington University | Compositions and methods for identifying autism spectrum disorders |
| US20120178637A1 (en) * | 2009-07-07 | 2012-07-12 | Abbott Laboratories | Biomarkers and methods for detecting alzheimer's disease |
| US20110059861A1 (en) * | 2009-09-08 | 2011-03-10 | Nodality, Inc. | Analysis of cell networks |
| US20130123124A1 (en) * | 2010-03-12 | 2013-05-16 | Children's Medical Center Corporation | Methods and compositions for characterizing autism spectrum disorder based on gene expression patterns |
| WO2012119129A1 (en) * | 2011-03-02 | 2012-09-07 | Berg Biosystems, Llc | Interrogatory cell-based assays and uses thereof |
| CN107449921A (zh) * | 2012-05-22 | 2017-12-08 | 博格有限责任公司 | 用于鉴别药物诱导毒性标志物的基于细胞的探询式分析 |
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2013
- 2013-03-05 AU AU2013230045A patent/AU2013230045A1/en not_active Abandoned
- 2013-03-05 HK HK15106693.0A patent/HK1206393A1/xx unknown
- 2013-03-05 US US14/383,450 patent/US20150023949A1/en not_active Abandoned
- 2013-03-05 WO PCT/US2013/029201 patent/WO2013134315A1/en not_active Ceased
- 2013-03-05 KR KR20147028035A patent/KR20140140069A/ko not_active Withdrawn
- 2013-03-05 CN CN201380022420.3A patent/CN104364393A/zh active Pending
- 2013-03-05 CA CA2866407A patent/CA2866407A1/en not_active Abandoned
- 2013-03-05 EP EP13758001.5A patent/EP2823063A4/en not_active Withdrawn
- 2013-03-05 JP JP2014561056A patent/JP2015517801A/ja active Pending
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2017
- 2017-12-04 US US15/830,982 patent/US20180275146A1/en not_active Abandoned
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2018
- 2018-04-05 JP JP2018072819A patent/JP2018153184A/ja active Pending
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2019
- 2019-02-14 US US16/275,944 patent/US20190242909A1/en not_active Abandoned
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2020
- 2020-08-14 JP JP2020137031A patent/JP2020193986A/ja active Pending
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2021
- 2021-06-11 US US17/346,152 patent/US20220137070A1/en not_active Abandoned
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106714556A (zh) * | 2014-04-11 | 2017-05-24 | 美国控股实验室公司 | 用于测定自闭症谱系病症风险的方法和系统 |
| US11674948B2 (en) | 2014-04-11 | 2023-06-13 | Laboratory Corporation Of America Holdings | Methods and systems for determining autism spectrum disorder risk |
| CN114470009A (zh) * | 2015-05-22 | 2022-05-13 | 亚利桑那大学董事会 | 用于治疗自闭症谱系障碍及相关症状的方法 |
| CN106885858A (zh) * | 2017-03-10 | 2017-06-23 | 方雷 | 一种高效的痕量临床病人样本的高通量全蛋白组学定量分析方法 |
| CN107312846A (zh) * | 2017-07-12 | 2017-11-03 | 北京赛尔维康生物医学科技有限公司 | Capg和ptgis基因在制备脊柱侧弯检测试剂盒中的应用 |
| CN109212226A (zh) * | 2018-09-06 | 2019-01-15 | 中国人民解放军兰州军区兰州总医院 | 预测急性高山病发病风险的血浆蛋白标志物及其在制备诊断ams易感性试剂盒中的应用 |
| CN109212226B (zh) * | 2018-09-06 | 2021-04-06 | 中国人民解放军联勤保障部队第九〇四医院 | 预测急性高山病发病风险的血浆蛋白标志物及其在制备诊断ams易感性试剂盒中的应用 |
| CN109239334A (zh) * | 2018-09-10 | 2019-01-18 | 吉林大学 | 建立时间分辨荧光免疫层析法检测MxA试剂盒 |
| CN112442527A (zh) * | 2019-08-27 | 2021-03-05 | 深圳市英马诺生物科技有限公司 | 孤独症诊断试剂盒、基因芯片、基因靶点筛选方法及应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013134315A1 (en) | 2013-09-12 |
| EP2823063A4 (en) | 2016-02-10 |
| JP2018153184A (ja) | 2018-10-04 |
| US20150023949A1 (en) | 2015-01-22 |
| HK1206393A1 (en) | 2016-01-08 |
| AU2013230045A1 (en) | 2014-09-11 |
| US20180275146A1 (en) | 2018-09-27 |
| JP2020193986A (ja) | 2020-12-03 |
| JP2015517801A (ja) | 2015-06-25 |
| EP2823063A1 (en) | 2015-01-14 |
| US20190242909A1 (en) | 2019-08-08 |
| CA2866407A1 (en) | 2013-09-12 |
| US20220137070A1 (en) | 2022-05-05 |
| KR20140140069A (ko) | 2014-12-08 |
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