CN104352856A - Traditional Chinese medicine composition for treating recurrent oral ulceration - Google Patents

Traditional Chinese medicine composition for treating recurrent oral ulceration Download PDF

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CN104352856A
CN104352856A CN201410625057.0A CN201410625057A CN104352856A CN 104352856 A CN104352856 A CN 104352856A CN 201410625057 A CN201410625057 A CN 201410625057A CN 104352856 A CN104352856 A CN 104352856A
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魏本雪
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/483Gleditsia (locust)
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
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    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
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    • A61K36/725Ziziphus, e.g. jujube
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    • A61K36/88Liliopsida (monocotyledons)
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    • A61K36/8884Arisaema, e.g. Jack in the pulpit
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    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla

Abstract

The invention discloses a traditional Chinese medicine composition for treating recurrent oral ulceration, belonging to the field of traditional Chinese medicines. The traditional Chinese medicine composition for treating recurrent oral ulceration disclosed by the invention is prepared from the following medicinal raw materials in parts by weight: 10 parts of indigo naturalis, 10 parts of radix pseudostellariae, 8 parts of mulberry, 8 parts of phaseolus calcaratus, 10 parts of vervain, 8 parts of houttuynia cordata, 6 parts of muskroot-like semiaquilegia root, 6 parts of selfheal, 6 parts of rhizoma arisaematis, 6 parts of cynanchum paniculatum, 12 parts of wild chrysanthemum flower, 8 parts of corn stigma, 6 parts of large-leaved gentian, 12 parts of lophatherum gracile, 6 parts of spina gleditsiae, 8 parts of lithospermum, 12 parts of spina date seed, 8 parts of apiary, 8 parts of rhizoma smilacis glabrae and 6 parts of the seed of cowherb. According to the invention, natural traditional Chinese medicines are used as the raw materials, therefore, the traditional Chinese medicine composition is accurate in curative effect, free of toxic and side effect and can be used for effectively treating recurrent oral ulceration with a low relapse rate; furthermore, the effective rate is up to 98%.

Description

A kind of Chinese medicine composition for the treatment of recurrent oral ulceration
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of recurrent oral ulceration, belong to the field of Chinese medicines.
Background technology
Recurrent aphtha, also known as recurrent aphthous stomatitis, recurrent oral ulceration, recurrent aphtha, it is a kind of disease that in oral keritonocytes, sickness rate is the highest, common cold, dyspepsia, psychentonia, the gloomy situation such as discomfort all accidentally can cause the generation of this disease, be apt to occur in lip, cheek, lingual margin etc., all can occur at any position of mucosa, but attached gingiva and hard palate are then rare completely in keratinization.Age of onset is generally between 10 ~ 30 years old, and women is more, all can occur throughout the year.Recurrent aphtha has self limiting, can spontaneous recovery in about 10 days.This disease has the features such as periodicity, recurrent and self limiting.
Current treatment recurrent oral ulceration has the method such as antibiotic medicine for oral administration, mealy medicine external application, but therapeutic effect is not obvious, particularly uses application, and the pain increased, sialorrhea more than, and patient is difficult to accept.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of recurrent oral ulceration, this Chinese medicine composition determined curative effect, instant effect and having no side effect.
Technical scheme of the present invention is:
Treating a Chinese medicine composition for recurrent oral ulceration, is be made up of the crude drug of following weight parts: Indigo Naturalis 10, Radix Pseudostellariae 10, Fructus Mori 8, Semen Phaseoli 8, Herba Verbenae 10, Herba Houttuyniae 8, Radix Semiaquilegiae 6, Spica Prunellae 6, Rhizoma Arisaematis 6, Radix Cynanchi Paniculati 6, Flos Chrysanthemi Indici 12, Stigma Maydis 8, Radix Gentianae Macrophyllae 6, Herba Lophatheri 12, Spina Gleditsiae 6, Radix Arnebiae (Radix Lithospermi) 8, Semen Ziziphi Spinosae 12, Nidus Vespae 8, upper Poria 8, Semen Vaccariae 6.
Preparation and instructions of taking: be decocted in water for oral dose, every day, potion, divided twice one after each meal sooner or later.
The pharmacological action of each Chinese medicine:
Indigo Naturalis: salty, cold.Return Liver Channel.Effect with cure mainly: heat-clearing and toxic substances removing, removing heat from blood, arresting convulsion.For maculae caused by violent heat pathogen, heat in blood tells nosebleed, chest pain hemoptysis, aphtha, mumps, sore throat, pediatric epilepsy scared.
Radix Pseudostellariae: sweet, micro-hardship is flat.Return spleen, lung meridian.Effect with cure mainly: replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung.Tired for insufficiency of the spleen body, inappetence, weak after being ill, deficiency of both vital energy and Yin, spontaneous perspiration is thirsty, dryness of the lung dry cough.
Fructus Mori: sweet, sour, cold.GUIXIN, liver, kidney channel.Effect with cure mainly: YIN nourishing of enriching blood, promote the production of body fluid and moisturize.For vertigo and tinnitus, palpitation and insomnia, early whitening of beard and hair, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, blood deficiency and constipation.
Semen Phaseoli: sweet, sour is flat.GUIXIN, small intestine meridian.Effect with cure mainly: inducing diuresis to remove edema, removing toxic substances and promoting pus discharge.For edema distension, beriberi limb swells, jaundice dark coloured urine, beriberoid pyretic arthralgia, carbuncle sore tumefacting virus, abdominalgia with intestinal abscess.
Herba Verbenae: bitter, cool.Return liver, board warp.Effect with cure mainly: promoting blood circulation to remove blood stasis, preventing the attack (or recurrence) of malaria, removing toxic substances, inducing diuresis to remove edema.Yu lumps in the chest and abdomen, amenorrhea dysmenorrhea, malaria, sore throat, carbuncle, edema, pyretic stranguria.
Herba Houttuyniae: pungent, is slightly cold.Return lung meridian.Effect with cure mainly: heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, inducing diuresis for treating stranguria syndrome.For lung abscess vomiting pus, expectorant dyspnea of heat type is coughed, hematodiarrhoea, pyretic stranguria, carbuncle sore tumefacting virus.
Radix Semiaquilegiae: sweet, bitter, cold.Return liver, stomach warp.Effect with cure mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle furuncle, mastalgia, scrofula is sick, venom.
Spica Prunellae: pungent, bitter, cold.Return liver, gallbladder meridian.Effect with cure mainly: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Rhizoma Arisaematis: bitter, pungent, temperature; Poisonous.Return lung, liver, spleen channel.Effect with cure mainly: drying dampness to eliminate phlegm, expelling wind and relieving convulsion, mass dissipating and swelling eliminating.For pertinacious phlegm cough, paralysis is dizzy, and middle wind-phlegm is stopped up, and mouth limit is crooked, hemiplegia; Epilepsy, infantile convulsion, tetanus.Life uses external treatment carbuncle, snake bite and insect sting.
Radix Cynanchi Paniculati: pungent, temperature.Return liver, stomach warp.Effect with cure mainly: removing dampness of dispeling the wind, antalgesic-antipruritic.For rheumatic arthralgia, stomachache distension, toothache, lumbago, injury from falling down; Urticaria, eczema.
Flos Chrysanthemi Indici: bitter, pungent, is slightly cold.Return liver, heart channel.Effect with cure mainly: heat-clearing and toxic substances removing.For furuncle carbuncle, conjunctival congestion and swelling pain.Have a headache dizzy.
Stigma Maydis: sweet is flat.Return bladder, liver, gallbladder meridian.Effect with cure mainly: promoting the function of the gallbladder to alleviate jaundice, diuresis detumescent, hemostasis.Control oedema due to nephritis, beriberi, icterohepatitis, hypertension, cholecystitis, cholelithiasis, diabetes, hematemesis and epistaxis, nasal sinusitis, acute mastitis.
Radix Gentianae Macrophyllae: pungent, bitter is flat.Return stomach, liver, gallbladder meridian.Effect with cure mainly: wind-damp dispelling, clearing away damp-heat, stopping numbness pain.For rheumatic arthralgia, the contracture of muscle arteries and veins, joint is ached, and day feeds hectic fever, and infantile malnutrition generates heat.
Herba Lophatheri: sweet, light, cold.GUIXIN, stomach, small intestine meridian.Effect with cure mainly: clearing heat and relieving fidgetness, diuresis.For calentura excessive thirst, hot urination drenches pain, aphtha of the mouth and tongue.
Spina Gleditsiae: pungent, temperature.Return liver, stomach warp.Effect with cure mainly: poison holding of subsiding a swelling, evacuation of pus, parasite killing.For carbuncle from the beginning of or difficulty in discharging of pus; External treatment scabies leprosy.
Radix Arnebiae (Radix Lithospermi): sweet, salty, cold.GUIXIN, Liver Channel.Effect with cure mainly: removing heat from blood, invigorate blood circulation, removing toxic substances rash.Contain for heat in blood poison, class's rash purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.
Semen Ziziphi Spinosae: sweet, sour is flat.Return liver, gallbladder, heart channel.Effect with cure mainly: tonifying liver, mind calming, arresting sweating, promotes the production of body fluid.For restlessness of asrhenia type and insomnia, palpitation with fear dreaminess, the empty hyperhidrosis of body, Tianjin wound is thirsty.
Nidus Vespae: sweet is flat.Return stomach warp.Effect with cure mainly: dispel the wind, counteracting toxic substances, parasite killing, pain relieving.In toothache due to dental caries, sore swollen toxin, acute mastitis, scrofula, skin stubborn dermatitis, fungal infection of hand and foot.
Upper Poria: sweet, light is flat.Return liver, stomach warp.Effect with cure mainly: dehumidify, detoxify, easing joint movement.For damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula is sick, scabies, syphilis and the limbs contracture caused by mercurialism, bones and muscles pain.
Semen Vaccariae: bitter is flat.Return liver, stomach warp.Effect with cure mainly: promoting blood circulation to restore menstrual flow, stimulating milk secretion subside a swelling.For agalactia, amenorrhea, dysmenorrhea, acute mastitis swells and ache.
The invention has the beneficial effects as follows: the present invention adopts natural Chinese medicine to be raw material, determined curative effect and having no side effect, can effectively cure recurrent oral ulceration and not easily recur, effective percentage reaches 98%.
Below in conjunction with clinical trial, the present invention is further described.
One, clinical trial
1, clinical data: between 2 years year June of in June, 2012 to 2014, altogether observe 16-57 year Blood of Patients with Recurrent Oral 100 example, its mean age is 32.5 years old.
2, diagnosis basis:
(1), with oral mucosa occur ulcer that is single or several diameter 3 ~ 5mm, scorching hot pain is cardinal symptom;
(2), onset is very fast, healing in general about 7 days, if down here, then and course of disease prolongation.More normal easily recurrence after;
(3), examination of mouth: stomatocace is comparatively shown shallow, circular or oval, quantity 1 ~ 2 at least, and more than 10 at most, surface has faint yellow secretions to adhere to, and ulcer surrounding mucosa is mostly congested.
3, Therapeutic Method: wherein treatment group takes Chinese medicine of the present invention, is decocted in water for oral dose, every day potion, point sooner or later twice one after each meal 3 days is 1 course for the treatment of.
4, curative effect determinate standard:
Recovery from illness: recurrent oral ulceration heals, local is without sense of discomfort;
Take a turn for the better: although have recurrence during aphtha, quantity reduces, and degree alleviates;
Invalid: aphtha symptom and ulcer are without significant change.
5, therapeutic outcome: at Clinical practice medicine of the present invention, take medicine 100 routine patients, take medicine after 1 course for the treatment of, symptom is obviously alleviated, and after 1 course for the treatment of of continuing to take medicine, recovery from illness 87 example, effective 11 examples, total effective rate is 98%.
Detailed description of the invention
Embodiment 1
Proportioning (unit: weight portion):
Indigo Naturalis 10, Radix Pseudostellariae 10, Fructus Mori 8, Semen Phaseoli 8, Herba Verbenae 10, Herba Houttuyniae 8, Radix Semiaquilegiae 6, Spica Prunellae 6, Rhizoma Arisaematis 6, Radix Cynanchi Paniculati 6, Flos Chrysanthemi Indici 12, Stigma Maydis 8, Radix Gentianae Macrophyllae 6, Herba Lophatheri 12, Spina Gleditsiae 6, Radix Arnebiae (Radix Lithospermi) 8, Semen Ziziphi Spinosae 12, Nidus Vespae 8, upper Poria 8, Semen Vaccariae 6.
Preparation and instructions of taking: be decocted in water for oral dose, every day, potion, divided twice one after each meal sooner or later.

Claims (1)

1. treat the Chinese medicine composition of recurrent oral ulceration for one kind, it is characterized in that, be made up of the crude drug of following weight parts: Indigo Naturalis 10, Radix Pseudostellariae 10, Fructus Mori 8, Semen Phaseoli 8, Herba Verbenae 10, Herba Houttuyniae 8, Radix Semiaquilegiae 6, Spica Prunellae 6, Rhizoma Arisaematis 6, Radix Cynanchi Paniculati 6, Flos Chrysanthemi Indici 12, Stigma Maydis 8, Radix Gentianae Macrophyllae 6, Herba Lophatheri 12, Spina Gleditsiae 6, Radix Arnebiae (Radix Lithospermi) 8, Semen Ziziphi Spinosae 12, Nidus Vespae 8, upper Poria 8, Semen Vaccariae 6.
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105055758A (en) * 2015-09-06 2015-11-18 王璐 Traditional Chinese medicine for treating stomatitis
CN106038431A (en) * 2016-08-08 2016-10-26 周素敏 Oral care solution used after neurosurgical operation and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
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CN103623385A (en) * 2013-12-17 2014-03-12 王少华 Traditional Chinese medicine for treating dental ulcer
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