CN104352836B - A kind of compound slimming effervescent tablet of the plant extracts containing Sunset Abelmoschus Root - Google Patents
A kind of compound slimming effervescent tablet of the plant extracts containing Sunset Abelmoschus Root Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/55—Liquid-liquid separation; Phase separation
Abstract
The invention discloses a kind of compound slimming effervescent tablet of plant extracts containing Sunset Abelmoschus Root, it is made up of the raw material of following weight component：10 ~ 14 parts of 50 ~ 70 parts of Sunset Abelmoschus Root rhizome, 20 ~ 50 parts of sunset abelmoschus flower, 1 ~ 5 part of lophatherum gracile, 2 ~ 5 parts of lotus leaf, 1 ~ 5 part of hawthorn, 1 ~ 3 part of rhizoma alismatis, 1 ~ 3 part of Chinese yam, 1 ~ 3 part of honey, 10 ~ 15 parts of citric acid, 8 ~ 12 parts of sodium acid carbonate and lactose.Method is as follows：Sunset Abelmoschus Root rhizome powder, lophatherum gracile, lotus leaf, hawthorn, Chinese yam and rhizoma alismatis are well mixed, extracting in water, sunset abelmoschus flower adds ethanol to extract, and tabletting packaging after addition citric acid, sodium acid carbonate and lactose is concentrated into after spray flux density, spray-drying process after extract solution is sunk through alcohol precipitation and water.The compound slimming effervescent tablet of the present invention is that natural plant is extracted, and by being reasonably formulated design, the peculiar fragrance with Sunset Abelmoschus Root is mellow, and fat-reducing effect is obvious, without any side effects, suitable long-term taking.
Description
Technical field
The present invention relates to solid beverage technical field, and in particular to a kind of compound slimming effervescent tablet containing Sunset Abelmoschus Root.
Background technology
Sunset Abelmoschus Root（Abelmoschus manihot（L.）Medic.）It is Malvaceae gumbo platymiscium, originates in Southwestern China
Area, is perennial herb, resident to make annual cultivation；Flowers and trees, yellow, center maroon；Summer at florescence, autumn.Bright Li Shizhen (1518-1593 A.D.)
《Compendium of Materia Medica》It is referred to as solely sage after the middle grinding the flower single to dissipate, for treating the diseases such as swollen ulcer drug.According to《Chinese Medicine major term
Allusion quotation》Record, Sunset Abelmoschus Root property is pungent, and slight bitter is cool.There are clearing heat and detoxicating, cooling blood and hemostasis, detumescence and apocenosis, modern medicine study hair
Existing, Sunset Abelmoschus Root is except rich in natural VE, the biological yellow cave of hydroxyl, phytosterol, catechin, complete protein, high glycan
Outside glue, dietary fiber, also containing trace elements of selenium largely beneficial to human body, zinc, iron, a variety of unsaponifiable matter etc..People can be adjusted
Secretion in vivo, strengthens the immunity of human body, improves cardiovascular and microcirculation function, strengthen antioxidant ability of organism, eliminate people
Body free radical；With anti-cardiac-cerebral ischemia anoxic, anti-inflammatory analgesic, antifatigue, anti-aging, anti-cancer and cancer-preventing, the god such as reducing blood sugar and blood lipid work(
Outstanding service is imitated.
Survey data shows that nearly more than 45% population of weight of China is exceeded.Modern is because operating pressure is big, rhythm of life
Constantly accelerate, cause to cause breakfast not eat, lunch is tackled, the bad life habits that supper is eaten and drunk extravagantly, unreasonable and uncontrolled
Diet cause the crowd of obesity to increase therewith, and then bring various diseases, such as three high diseases.Therefore, with fat-reducing effect
Product arises at the historic moment and lasting.Diet products on the market focus on fat-reducing effect simply at present, cause part drinking person production
Repiece it is dizzy, nauseous, nervous and diarrhoea etc. adverse reaction.
The content of the invention
It is an object of the invention to provide a kind of compound slimming effervescent tablet of plant extracts containing Sunset Abelmoschus Root, by reasonably matching somebody with somebody
Side's design, using Sunset Abelmoschus Root as the basis of slim tea, realizes science, the reducing blood sugar and blood lipid of safety to reach fat-reducing purpose.
To achieve the above object, the present invention uses following technical scheme：
A kind of compound slimming effervescent tablet containing Sunset Abelmoschus Root, it is made up of the raw material of following weight component：Sunset Abelmoschus Root rhizome
50 ~ 70 parts, 20 ~ 50 parts of sunset abelmoschus flower, 1 ~ 5 part of lophatherum gracile, 2 ~ 5 parts of lotus leaf, 1 ~ 5 part of hawthorn, 1 ~ 3 part of rhizoma alismatis, citric acid 10 ~ 15
10 ~ 14 parts of part, 8 ~ 12 parts of sodium acid carbonate and lactose.
As the preferred technical solution of the present invention, a kind of compound slimming effervescent tablet containing Sunset Abelmoschus Root, it is by following weight
The raw material of component is made：60 parts of Sunset Abelmoschus Root rhizome, 30 parts of sunset abelmoschus flower, 3 parts of lophatherum gracile, 4 parts of lotus leaf, 2 parts of hawthorn, 1 part of rhizoma alismatis,
12 parts of 12 parts of citric acid, 10 parts of sodium acid carbonate and lactose.
A kind of preparation method of the compound slimming effervescent tablet of plant extracts containing Sunset Abelmoschus Root, step is as follows：
（1）Extract：The cleaning of Sunset Abelmoschus Root rhizome crushes after drying and obtains Sunset Abelmoschus Root rhizome powder, by Sunset Abelmoschus Root rhizome powder, henon bamboo
Leaf, lotus leaf, hawthorn and rhizoma alismatis are well mixed, then add the water that parts by weight are 200 ~ 300 parts, heating is boiled 3 ~ 5 hours, quiet
Put takes supernatant liquor to be labeled as I after precipitation；Sunset abelmoschus flower is cleaned and dried, the then frying under conditions of 100 ~ 110 DEG C, cooling
After crush, it is 50 ~ 100 parts of ethanol then to add parts by weight, and refluxing extraction 2 ~ 3 hours under conditions of 70 ~ 80 DEG C are stood
Supernatant liquor is taken to be labeled as II after precipitation；
（2）Concentration：In vacuum be that -0.08mpa, temperature are under conditions of 75 ~ 80 DEG C by I, be concentrated into density for 1.14 ~
1.16g/mL, in vacuum is that -0.08mpa, temperature are under conditions of 50 ~ 65 DEG C, to be concentrated into density for 1.18 ~ 1.20g/ by II
mL；
（3）Alcohol precipitation：Equivalent ethanol is added in I after concentration and stands 12 ~ 24h, 50 ~ 60 DEG C of recovery ethanol are heated to, when
Between be 1 ~ 2 hour, be further concentrated to density for 1.18 ~ 1.20 g/mL；
（4）Water sinks：Mixed liquor is mixed to get by after I after alcohol precipitation and concentration II, water is added into mixed liquor, its reclaimed water
Weight be 3 ~ 5 times of mixed liquor weight, stand 12 ~ 24h, be concentrated into density for 1.12 ~ 1.20 g/mL；
（5）Film-making：By step（4）Mixed liquor spray-drying process after concentration, then adds citric acid, the carbon of formula ratio
Tabletting, packaging after sour hydrogen sodium and lactose are well mixed, the quality of every is 50 ~ 60mg.
Beneficial effects of the present invention：（1）Sunset Abelmoschus Root property is pungent, slight bitter, cool.Have clearing heat and detoxicating, hemostasis and anti-inflammation, detumescence and apocenosis it
Effect, can adjust human endocrine, strengthen the immunity of human body, improve cardiovascular and microcirculation function, strengthen body antioxygen
Change ability, eliminates human free radical；With anti-cardiac-cerebral ischemia anoxic, anti-inflammatory analgesic, blood drops in antifatigue, anti-aging, anti-cancer and cancer-preventing
The mystery effect such as glucemia fat work(.（2）Lophatherum gracile contains a large amount of flavones, lactone, polysaccharide, chlorophyll, amino acid, vitamin, micro
The nutrients such as element, and the flavones in lophatherum gracile has good antiradical activities, can effectively adjust human body blood fat, and have
Anti-inflammatory, antibacterial, antiviral, anti-oxidant, raising immunity lotus leaf have the effects such as clearing summer-heat and damp, sending up the lucid yang, cooling blood and hemostasis.
（3）Recent studies confirms that lotus leaf plays the role of good reducing blood lipid, norcholesterol and fat-reducing.（4）Hawthorn appetite-stimulating indigestion-relieving, especially
Meat stagnation effect is offseted more preferably while have prevention and cure of cardiovascular disease, reduce blood pressure with cholesterol, soften blood vessel and diuresis and
Sedation.（5）Rhizoma alismatis, clearing damp and promoting diuresis expels the heat-evil treating stranguria, main difficult urination, puckery pain of heat gonorrhea, oedema turgor；There is effect for reducing blood fat
There is protective effect to liver simultaneously.
The compound slimming effervescent tablet of the plant extracts containing Sunset Abelmoschus Root of the present invention is that natural plant is extracted, by rational
Formula design, makes it have the effect that general effervescent tablet for slimming is not reached, in good taste, the peculiar fragrance with Sunset Abelmoschus Root,
The delicate fragrance of lotus leaf and lophatherum gracile is equipped with, mellow, fat-reducing effect is obvious, without any side effects, suitable long-term taking.
The body mass index commonly used at present（body mass index）Abbreviation BMI, is translated into constitutional index again.It is a kind of meter
Calculate index of the height than body weight.Circular is with body weight（Kilogram, kg）Divided by height（Rice, m）Square, i.e. BMI=body
Weight/height/height（kg/m2）.Research shows that the percentage composition of most of individual body mass indexs and body fat has substantially
Correlation, can preferably reflect the obese degree of body, as shown in table 1.
Table 1
The effervescent tablet of compound slimming containing the Sunset Abelmoschus Root fat-reducing of the present invention and lipid-lowering effect test data：
Choose the Simple Obesity Patient of Henan Province JIAOZUO AREA 160（BMI ≥ 28）Take the compound containing Sunset Abelmoschus Root
Effervescent tablet for slimming, wherein having male 80, women 80, the range of age is 14 ~ 60 years old, by above-mentioned 160 pure fertilizer
Fat patient is random, be divided into four test groups, and every group of 40 patients, wherein test group 1 takes the embodiment of the present invention 1
The compound slimming effervescent tablet of the plant extracts containing Sunset Abelmoschus Root, test group 2 take the compound containing Sunset Abelmoschus Root of the embodiment of the present invention 2
Effervescent tablet for slimming, test group 3 are taken the compound slimming effervescent tablet containing Sunset Abelmoschus Root of the embodiment of the present invention 3, test group 4 and taken
The compound slimming effervescent tablet of the plant extracts containing Sunset Abelmoschus Root of the embodiment of the present invention 4.
The method for taking the compound slimming effervescent tablet of the plant extracts containing Sunset Abelmoschus Root：Everyone noon, night after meal 1 daily
Take once, each taking two panels, continuously drink two months after hour.
Fat-reducing effect：Test group 1：100% weight in patients declines, wherein the BMI of 35 patients is down to 18.5 ~ 24
Between（Belong to healthy weight scope）, the BMI of 5 patients is down between 24 ~ 28.Test group 2：100% weight in patients
Decline, wherein the BMI of 30 patients is down between 18.5 ~ 24（Belong to healthy weight scope）, the BMI of 10 patients is down to
Between 24 ~ 28.Test group 3：100% weight in patients declines, wherein the BMI of 34 patients is down between 18.5 ~ 24（Category
In healthy weight scope）, the BMI of 6 patients is down between 24 ~ 28.Test group 4：100% weight in patients declines, its
In the BMI of 38 patients be down between 18.5 ~ 24（Belong to healthy weight scope）, the BMI of 2 patients be down to 24 ~ 28 it
Between.All patients, which stop drinking body weight in later six months, substantially not to rebound, and has no adverse reaction after drinking, and gastrointestinal disturbances are inhaled
Receive function normal.
Embodiment
Embodiment 1
The compound slimming effervescent tablet of the plant extracts containing Sunset Abelmoschus Root of the present embodiment, by the raw material system of following weight component
Into：50 parts of Sunset Abelmoschus Root rhizome, 20 parts of sunset abelmoschus flower, 1 part of lophatherum gracile, 2 parts of lotus leaf, 1 part of hawthorn, 1 part of rhizoma alismatis, 10 parts of citric acid,
10 parts of 8 parts of sodium acid carbonate and lactose.
The preparation method of the compound slimming effervescent tablet of the plant extracts containing Sunset Abelmoschus Root of the present embodiment, step is as follows：
（1）Extract：The cleaning of Sunset Abelmoschus Root rhizome crushes after drying and obtains Sunset Abelmoschus Root rhizome powder, by Sunset Abelmoschus Root rhizome powder, henon bamboo
Leaf, lotus leaf, hawthorn and rhizoma alismatis are well mixed, then add the water that parts by weight are 200 parts, and heating is boiled 3 hours, staticly settled
After take supernatant liquor be labeled as I；Sunset abelmoschus flower is cleaned and dried, the then frying under conditions of 100 DEG C is crushed, so after cooling
The ethanol that parts by weight are 50 parts is added afterwards, and refluxing extraction 2 hours under conditions of 70 DEG C take supernatant liquor mark after staticly settling
It is designated as II；
（2）Concentration：In vacuum it is that -0.08mpa, temperature are under conditions of 75 DEG C, to be concentrated into density for 1.14g/ by I
ML, in vacuum is that -0.08mpa, temperature are under conditions of 50 DEG C, to be concentrated into density for 1.18g/mL by II；
（3）Alcohol precipitation：Equivalent ethanol is added in I after concentration and stands 12h, 50 DEG C of recovery ethanol are heated to, the time is 1 small
When, density is further concentrated to for 1.18 g/mL；
（4）Water sinks：Mixed liquor is mixed to get by after I after alcohol precipitation and concentration II, 3 times of mixed liquor is added into mixed liquor
Water, stand 12h, be concentrated into density for 1.12 g/mL；
（5）Film-making：By step（4）Mixed liquor spray-drying process after concentration, then adds citric acid, the carbon of formula ratio
Tabletting, packaging after sour hydrogen sodium and lactose are well mixed.
Embodiment 2
The compound slimming effervescent tablet of the Sunset Abelmoschus Root plant extracts of the present embodiment, is made up of the raw material of following weight component：
70 parts of Sunset Abelmoschus Root rhizome, 50 parts of sunset abelmoschus flower, 5 parts of lophatherum gracile, 5 parts of lotus leaf, 5 parts of hawthorn, 3 parts of rhizoma alismatis, 15 parts of citric acid, carbonic acid
14 parts of 12 parts of hydrogen sodium and lactose.
The preparation method of the compound slimming effervescent tablet of the plant extracts containing Sunset Abelmoschus Root of the present embodiment, step is as follows：
（1）Extract：The cleaning of Sunset Abelmoschus Root rhizome crushes after drying and obtains Sunset Abelmoschus Root rhizome powder, by Sunset Abelmoschus Root rhizome powder, henon bamboo
Leaf, lotus leaf, hawthorn and rhizoma alismatis are well mixed, then add the water that parts by weight are 300 parts, and heating is boiled 5 hours, staticly settled
After take supernatant liquor be labeled as I；Sunset abelmoschus flower is cleaned and dried, the then frying under conditions of 110 DEG C is crushed, so after cooling
The ethanol that parts by weight are 100 parts is added afterwards, and refluxing extraction 3 hours under conditions of 80 DEG C take supernatant liquor after staticly settling
Labeled as II；
（2）Concentration：In vacuum it is that -0.08mpa, temperature are under conditions of 80 DEG C, to be concentrated into density for 1.16g/ by I
ML, in vacuum is that -0.08mpa, temperature are under conditions of 65 DEG C, to be concentrated into density for 1.20g/mL by II；
（3）Alcohol precipitation：Equivalent ethanol is added in I after concentration and stands 24h, 60 DEG C of recovery ethanol are heated to, the time is 2 small
When, density is further concentrated to for 1.20 g/mL；
（4）Water sinks：Mixed liquor is mixed to get by after I after alcohol precipitation and concentration II, 5 times of mixed liquor is added into mixed liquor
Water, stand 24h, be concentrated into density for 1.20 g/mL；
（5）Film-making：By step（4）Mixed liquor spray-drying process after concentration, then adds citric acid, the carbon of formula ratio
Tabletting, packaging after sour hydrogen sodium and lactose are well mixed.
Embodiment 3
The compound slimming effervescent tablet of the Sunset Abelmoschus Root plant extracts of the present embodiment, is made up of the raw material of following weight component：
60 parts of Sunset Abelmoschus Root rhizome, 30 parts of sunset abelmoschus flower, 2 parts of lophatherum gracile, 3 parts of lotus leaf, 4 parts of hawthorn, 2 parts of rhizoma alismatis, 12 parts of citric acid, carbonic acid
12 parts of 10 parts of hydrogen sodium and lactose.
The preparation method of the compound slimming effervescent tablet of the plant extracts containing Sunset Abelmoschus Root of the present embodiment, step is as follows：
（1）Extract：The cleaning of Sunset Abelmoschus Root rhizome crushes after drying and obtains Sunset Abelmoschus Root rhizome powder, by Sunset Abelmoschus Root rhizome powder, henon bamboo
Leaf, lotus leaf, hawthorn and rhizoma alismatis are well mixed, then add the water that parts by weight are 250 parts, and heating is boiled 4 hours, after staticly settling
Supernatant liquor is taken to be labeled as I；Sunset abelmoschus flower is cleaned and dried, the then frying under conditions of 105 DEG C is crushed, then after cooling
The ethanol that parts by weight are 80 parts is added, refluxing extraction 2.5 hours under conditions of 75 DEG C take supernatant liquor mark after staticly settling
It is designated as II；
（2）Concentration：In vacuum it is that -0.08mpa, temperature are under conditions of 78 DEG C, to be concentrated into density for 1.15g/ by I
ML, in vacuum is that -0.08mpa, temperature are under conditions of 60 DEG C, to be concentrated into density for 1.19g/mL by II；
（3）Alcohol precipitation：Equivalent ethanol is added in I after concentration and stands 20h, 55 DEG C of recovery ethanol are heated to, the time is 1.5
Hour, density is further concentrated to for 1.19 g/mL；
（4）Water sinks：Mixed liquor is mixed to get by after I after alcohol precipitation and concentration II, 4 times of mixed liquor is added into mixed liquor
Water, stand 15h, be concentrated into density for 1.15 g/mL；
（5）Film-making：By step（4）Mixed liquor spray-drying process after concentration, then adds citric acid, the carbon of formula ratio
Tabletting, packaging after sour hydrogen sodium and lactose are well mixed.
Embodiment 4
The compound slimming effervescent tablet of the plant extracts containing Sunset Abelmoschus Root of the present embodiment, by the raw material system of following weight component
Into：60 parts of Sunset Abelmoschus Root rhizome, 30 parts of sunset abelmoschus flower, 3 parts of lophatherum gracile, 4 parts of lotus leaf, 2 parts of hawthorn, 1 part of rhizoma alismatis, 12 parts of citric acid,
12 parts of 10 parts of sodium acid carbonate and lactose.
The preparation method of the compound slimming effervescent tablet of the plant extracts containing Sunset Abelmoschus Root of the present embodiment, step is as follows：
（1）Extract：The cleaning of Sunset Abelmoschus Root rhizome crushes after drying and obtains Sunset Abelmoschus Root rhizome powder, by Sunset Abelmoschus Root rhizome powder, henon bamboo
Leaf, lotus leaf, hawthorn and rhizoma alismatis are well mixed, then add the water that parts by weight are 280 parts, and heating is boiled 4 hours, staticly settled
After take supernatant liquor be labeled as I；Sunset abelmoschus flower is cleaned and dried, the then frying under conditions of 105 DEG C is crushed, so after cooling
The ethanol that parts by weight are 50 ~ 100 parts is added afterwards, and refluxing extraction 3 hours under conditions of 78 DEG C take upper strata clear after staticly settling
Liquid is labeled as II；
（2）Concentration：In vacuum it is that -0.08mpa, temperature are under conditions of 80 DEG C, to be concentrated into density for 1.14g/ by I
ML, in vacuum is that -0.08mpa, temperature are under conditions of 50 ~ 65 DEG C, to be concentrated into density for 1.18g/mL by II；
（3）Alcohol precipitation：Equivalent ethanol is added in I after concentration and stands 15h, 58 DEG C of recovery ethanol are heated to, the time is 2 small
When, density is further concentrated to for 1.20/mL；
（4）Water sinks：Mixed liquor is mixed to get by after I after alcohol precipitation and concentration II, 4 times of mixed liquor is added into mixed liquor
Water, stand 18h, be concentrated into density for 1.18/mL；
（5）Film-making：By step（4）Mixed liquor spray-drying process after concentration, then adds citric acid, the carbon of formula ratio
Tabletting, packaging after sour hydrogen sodium and lactose are well mixed.
The foregoing is only a specific embodiment of the invention, but protection scope of the present invention is not limited thereto, any
Belong to those skilled in the art the invention discloses technical scope in, the change or replacement that can be readily occurred in, all should
It is included within the scope of the present invention.Therefore, protection scope of the present invention should be defined by scope of the claims.
Claims (3)
1. the compound slimming effervescent tablet of a kind of plant extracts containing Sunset Abelmoschus Root, it is characterised in that it is by the original of following weight component
Material is made：50 ~ 70 parts of Sunset Abelmoschus Root rhizome, 20 ~ 50 parts of sunset abelmoschus flower, 1 ~ 5 part of lophatherum gracile, 2 ~ 5 parts of lotus leaf, 1 ~ 5 part of hawthorn, rhizoma alismatis
10 ~ 14 parts of 1 ~ 3 part, 1 ~ 3 part of Chinese yam, 1 ~ 3 part of honey, 10 ~ 15 parts of citric acid, 8 ~ 12 parts of sodium acid carbonate and lactose.
2. a kind of compound slimming effervescent tablet of plant extracts containing Sunset Abelmoschus Root according to claim 1, it is characterised in that it
It is made up of the raw material of following weight component：60 parts of Sunset Abelmoschus Root rhizome, 30 parts of sunset abelmoschus flower, 3 parts of lophatherum gracile, 4 parts of lotus leaf, hawthorn
12 parts of 2 parts, 1 part of rhizoma alismatis, 2 parts of Chinese yam, 1 part of honey, 12 parts of citric acid, 10 parts of sodium acid carbonate and lactose.
3. the preparation method of the compound slimming effervescent tablet of the plant extracts according to claim 1 or 2 containing Sunset Abelmoschus Root, it is special
Levy and be that step is as follows：
（1）Extract：The cleaning of Sunset Abelmoschus Root rhizome crushes after drying and obtains Sunset Abelmoschus Root rhizome powder, by Sunset Abelmoschus Root rhizome powder, lophatherum gracile, lotus
Leaf, hawthorn, Chinese yam and rhizoma alismatis are well mixed, then add the water that parts by weight are 200 ~ 300 parts, heating is boiled 3 ~ 5 hours, quiet
Put takes supernatant liquor to be labeled as I after precipitation；Sunset abelmoschus flower is cleaned and dried, the then frying under conditions of 100 ~ 110 DEG C, cooling
After crush, it is 50 ~ 100 parts of ethanol then to add parts by weight, and refluxing extraction 2 ~ 3 hours under conditions of 70 ~ 80 DEG C are stood
Supernatant liquor is taken to be labeled as II after precipitation；
（2）Concentration：In vacuum be that -0.08mpa, temperature are under conditions of 75 ~ 80 DEG C by I, be concentrated into density for 1.14 ~
1.16g/mL, in vacuum is that -0.08mpa, temperature are under conditions of 50 ~ 65 DEG C, to be concentrated into density for 1.18 ~ 1.20g/ by II
mL；
（3）Alcohol precipitation：Equivalent ethanol is added in I after concentration and stands 12 ~ 24h, 50 ~ 60 DEG C of recovery ethanol are heated to, the time is 1
~ 2 hours, density was further concentrated to for 1.18 ~ 1.20 g/mL；
（4）Water sinks：Mixed liquor is mixed to get by after I after alcohol precipitation and concentration II, water is added into mixed liquor, the weight of its reclaimed water
Amount is 3 ~ 5 times of mixed liquor weight, stands 12 ~ 24h, is concentrated into density for 1.12 ~ 1.20 g/mL；
（5）Film-making：By step（4）Mixed liquor and honey mixing, spray-drying process after concentration, then add the lemon of formula ratio
Lemon acid, sodium acid carbonate and the well mixed rear tabletting of lactose, packaging.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103099089A (en) * | 2012-11-09 | 2013-05-15 | 刘东元 | Health-care product for reducing blood sugar and blood pressure, relaxing bowels, losing weight, resisting fatigue and improving sexual function and production technology thereof |
| CN103211258A (en) * | 2013-04-22 | 2013-07-24 | 河南省淼雨饮品股份有限公司 | Weight-losing apple vinegar health drink and preparation method thereof |
| CN103652203A (en) * | 2014-01-03 | 2014-03-26 | 山东金硕生物科技股份有限公司 | Abelmoschus manihot medic tea bag and preparation method |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103099089A (en) * | 2012-11-09 | 2013-05-15 | 刘东元 | Health-care product for reducing blood sugar and blood pressure, relaxing bowels, losing weight, resisting fatigue and improving sexual function and production technology thereof |
| CN103211258A (en) * | 2013-04-22 | 2013-07-24 | 河南省淼雨饮品股份有限公司 | Weight-losing apple vinegar health drink and preparation method thereof |
| CN103652203A (en) * | 2014-01-03 | 2014-03-26 | 山东金硕生物科技股份有限公司 | Abelmoschus manihot medic tea bag and preparation method |
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| 黄蜀葵的资源及药学研究进展;巩江等;《安徽农业科学》;20091231;第37卷(第15期);6979-6980 * |
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Address after: 454003 Zhenning Guo Ning District, Jiaozuo hi tech Zone, Henan Applicant after: JIAOZUO JULY FLOWER BIOTECHNOLOGY CO., LTD. Address before: 454003 Zhenning Guo Ning District, Jiaozuo hi tech Zone, Henan Applicant before: JIAOZUO JULY FLOWER BIOTECHNOLOGY CO., LTD. |
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Inventor after: Zhang Chunguang Inventor after: Yang Huan Inventor after: Zhao Xiang Inventor after: Wang Tian Inventor before: Yang Huan Inventor before: Zhao Xiang Inventor before: Wang Ting Inventor before: Zhou Peng |
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Address after: Room 426, 1356 Hanghai East Road, Jingkai District, Zhengzhou City, Henan Province Patentee after: Henan July Peanut Biotechnology Co., Ltd. Address before: 454003 Zhenning Guo Ning District, Jiaozuo hi tech Zone, Henan Patentee before: Henan July Peanut Biotechnology Co., Ltd. |