CN104352653A - Medicine for treating asthma and preparation method thereof - Google Patents

Medicine for treating asthma and preparation method thereof Download PDF

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Publication number
CN104352653A
CN104352653A CN201410739940.2A CN201410739940A CN104352653A CN 104352653 A CN104352653 A CN 104352653A CN 201410739940 A CN201410739940 A CN 201410739940A CN 104352653 A CN104352653 A CN 104352653A
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asthma
herba
chinese medicine
medicine composition
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不公告发明人
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532—Agastache, e.g. giant hyssop
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
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  • Marine Sciences & Fisheries (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a traditional Chinese medicine composition for treating asthma. According to the medicine, the asthma can be well treated and does not reoccur. The traditional Chinese medicine composition for treating asthma consists of the following components in parts by weight: 15-20 parts of loquat leaf, 15-20 parts of radix asteris, 10-15 parts of ephedra, 10-15 parts of dandelion, 10-15 parts of chamomile, 10-15 parts of Agastache rugosus, 5-10 parts of cortex lycii radicis, 5-10 parts of liquorice, 5-10 parts of bighead atractylodes rhizome, 1-5 parts of pearl powder, 1-5 parts of burdock and 1-5 parts of kapok.

Description

Medicine for the treatment of asthma and preparation method thereof
the application is divisional application, the application number of original application201310441723.0, the applying date2013.09.26, denomination of invention:a kind of Chinese medicine composition for the treatment of asthma.
Technical field
The present invention relates to a kind of medicine for the treatment of asthma, be specifically related to a kind of compositions be made up of Chinese medicine ingredients, belong to medical art.
Background technology
Asthma is a kind of commonly encountered diseases, frequently-occurring disease, at present, and global asthmatic patient about 300,000,000 people, Chinese patients with asthma about 3,000 ten thousand.The common sympton of asthmatic patient be paroxysmally to pant, the symptom such as out of breath, uncomfortable in chest or cough, small number of patients may take also chest pain as main manifestations.The risk factor of asthma comprises host factor (inherited genetic factors) and environmental factors two aspects.Inherited genetic factors can embody with it a lot of patient, in the middle of the relatives of such as most patient (have relationship by blood, nearly three generations people), asthma (recurrent cough, pant) or other anaphylactic diseases (allergic rhinitis, atopic dermatitis) medical history can be traced back to.Most of asthmatic patient belongs to allergic constitution, itself may with allergic rhinitis and/atopic dermatitis, or the allergen (acarid, pollen, house pet, mycete etc.), some food (nut, milk, Semen arachidis hypogaeae, seafood etc.), drug allergy etc. to common air-borne transmission.Asthma affects the able-bodied important diseases of people, treatment not in time, lack of standardization, asthma may be fatal, and it is extremely important therefore to treat asthma in time.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of asthma andpreparation method, this medicine can be good at treating asthma, and without recurrence.
Technical solution of the present invention is as follows:
Treat a Chinese medicine composition for asthma, it is characterized in that being grouped into by the one-tenth of following weight portion: Folium Eriobotryae 15-20 part, Radix Asteris 15-20 part, Herba Ephedrae 10-15 part, Herba Taraxaci 10-15 part, Flos Matricariae chamomillae 10-15 part, Herba Pogostemonis 10-15 part, Cortex Lycii 5-10 part, Radix Glycyrrhizae 5-10 part, Rhizoma Atractylodis Macrocephalae 5-10 part, Margarita powder 1-5 part, Fructus Arctii 1-5 part, Flos Bombacis Malabarici 1-5 part.
Preferably, when each composition adopts following consumption, effect is best: Folium Eriobotryae 16 parts, Radix Asteris 16 parts, 12 parts, Herba Ephedrae, Herba Taraxaci 12 parts, Flos Matricariae chamomillae 12 parts, Herba Pogostemonis 12 parts, Cortex Lycii 6 parts, 6 parts, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae 6 parts, Margarita powder 4 parts, Fructus Arctii 4 parts, Flos Bombacis Malabarici 4 parts.
The present invention, mainly through the cooperation of each medicine, plays effect of heat-clearing and toxic substances removing, damp eliminating eliminating stagnation, moistening the lung and resolving phlegm, relieving cough and asthma, and each crude drug effect is as follows:
Folium Eriobotryae, attaches to the lung and stomach meridians, and has effect of clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI, for cough due to lung-heat, and QI rising in reverse order dyspnea with rapid respiration, gastropyretic vomiting, hiccup.
Radix Asteris, has effect of nourishing the lung to keep the adverse QI downward, preventing phlegm from forming and stopping coughing, for cough, deficiency of the lung chronic cough, consumptive lung disease lung abscess, coughs vomiting bloody pus, dysuria.
Herba Ephedrae, has diaphoresis cold expelling, depressed lung-energy dispersing, and effect of inducing diuresis to remove edema, is used for chill exterior syndrome, uncomfortable in chestly breathes with cough, edema due to wind pathogen edema, rheumatic arthralgia, carbuncle of yin nature, sucutaneous nodule.
Herba Taraxaci, has effect of heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, for upper respiratory tract infection, eye conjunctivitis, mumps, hyperglycemia, pharyngitis, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, the disease such as acute bronchitis, urinary tract infection.
Flos Matricariae chamomillae, mildly bitter flavor, Gan Xiang, there is improving eyesight, move back liver-fire, effect of expelling phlegm for arresting cough, can Cure for insomnia, reduce blood pressure, can invigorate, refresh oneself, can effectively alleviate bronchitis and asthma, the myalgia that headache, migraine or the flu of can releiving causes, centering and gastric acid, calm nerves are helpful.
Herba Pogostemonis, enters lung, spleen, stomach warp, has effect of dispelling summer-heat from superficies of the body, removing dampness to restore normal function of the stomach, and for summertime flu, cold and heat are had a headache, and breast gastral cavity painful abdominal mass is vexed, and vomiting is had loose bowels, vomiting during pregnancy, nasal sinusitis, hands, tinea pedis.
Cortex Lycii, has removing heat from blood effect except steaming, lung heat clearing pathogenic fire reducing, for deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis.
Radix Glycyrrhizae, function invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
The Rhizoma Atractylodis Macrocephalae, has invigorating the spleen and replenishing QI, invigorating the spleen and regulating the stomach, dampness diuretic, the effect of the hidroschesis that reduces phlegm, and for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Margarita powder, has effect of arresting convulsion of calming the nerves, improving eyesight removing nebula, removing toxic substances and promoting granulation, and for insomnia of palpitating with fear, infantile convulsion epilepsy, the raw nebula of order, skin infection is not held back.
Fructus Arctii, has effect of dispelling wind and heat pathogens, lung qi dispersing rash, resolving toxin and disinhibiting the throat, for anemopyretic cold, and cough with copious phlegm, measles, rubella, laryngopharynx swelling and pain, cheek erysipelas of itching, carbuncle sore tumefacting virus.
Flos Bombacis Malabarici, has effect of heat clearing away, dampness removing, removing toxic substances, for having loose bowels, and dysentery, metrorrhagia, sore.
Process for preparing medicine of the present invention is simple, and dry, pulverize each ingredient to 80-120 object fine powder, mix homogeneously can use.
The present invention with Folium Eriobotryae, Radix Asteris, Herba Ephedrae, Herba Taraxaci, Flos Matricariae chamomillae, Herba Pogostemonis, Cortex Lycii, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae, Margarita powder, Fructus Arctii, Flos Bombacis Malabarici for ingredient, there is effect of heat-clearing and toxic substances removing, damp eliminating eliminating stagnation, moistening the lung and resolving phlegm, relieving cough and asthma, good therapeutical effect is had to asthma, rapid-action, without recurrence.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described, it is to be understood that following explanation is only to explain the present invention, do not limit its content.If following composition, without specified otherwise, is weight portion.
embodiment 1
Pharmaceutical formulation is as follows: Folium Eriobotryae 16 parts, Radix Asteris 16 parts, 12 parts, Herba Ephedrae, Herba Taraxaci 12 parts, Flos Matricariae chamomillae 12 parts, Herba Pogostemonis 12 parts, Cortex Lycii 6 parts, 6 parts, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae 6 parts, Margarita powder 4 parts, Fructus Arctii 4 parts, Flos Bombacis Malabarici 4 parts.
By mentioned component mix homogeneously, be ground into 80-120 object fine powder, obtain asthma drug of the present invention.
embodiment 2
Pharmaceutical formulation is as follows: Folium Eriobotryae 15 parts, Radix Asteris 20 parts, 10 parts, Herba Ephedrae, Herba Taraxaci 15 parts, Flos Matricariae chamomillae 10 parts, Herba Pogostemonis 15 parts, Cortex Lycii 5 parts, 10 parts, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae 5 parts, Margarita powder 5 parts, Fructus Arctii 1 part, Flos Bombacis Malabarici 5 parts.Preparation method is with embodiment 1.
embodiment 3
Pharmaceutical formulation is as follows: Folium Eriobotryae 20 parts, Radix Asteris 15 parts, 15 parts, Herba Ephedrae, Herba Taraxaci 10 parts, Flos Matricariae chamomillae 15 parts, Herba Pogostemonis 10 parts, Cortex Lycii 10 parts, 5 parts, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae 10 parts, Margarita powder 1 part, Fructus Arctii 5 parts, Flos Bombacis Malabarici 1 part.Preparation method is with embodiment 1.
embodiment 4
Pharmaceutical formulation is as follows: Folium Eriobotryae 15 parts, Radix Asteris 15 parts, 10 parts, Herba Ephedrae, Herba Taraxaci 10 parts, Flos Matricariae chamomillae 10 parts, Herba Pogostemonis 10 parts, Cortex Lycii 5 parts, 5 parts, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae 5 parts, Margarita powder 1 part, Fructus Arctii 1 part, Flos Bombacis Malabarici 1 part.
embodiment 5
Tablet of the present invention, formula is: Folium Eriobotryae 20 parts, Radix Asteris 20 parts, 15 parts, Herba Ephedrae, Herba Taraxaci 15 parts, Flos Matricariae chamomillae 15 parts, Herba Pogostemonis 15 parts, Cortex Lycii 10 parts, 10 parts, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae 10 parts, Margarita powder 5 parts, Fructus Arctii 5 parts, Flos Bombacis Malabarici 5 parts.Preparation method is with embodiment 1.
clinical trial
1, patient source
Screen 219 routine asthmatic patients from this city hospital outpatient, patients symptomatic is: during seizure of disease with cough, expectoration, pant, the symptom such as dyspnea, uncomfortable in chest and chest pain.Wherein, male 115 example, women 104 example, patient's mean age is 43.3 ± 5.5 years old, sick time 4.9 ± 2.3 years.
2, Therapeutic Method
Patient is divided into 3 groups, often organizes 73 people, between each group in sex, age, the course of disease no difference of science of statistics.When treating, above-mentioned 3 groups of patients are used respectively to the medicine of the embodiment of the present invention 1,2,4, every day 3 times, each 6g.Continuous use, after 2 weeks, observes therapeutic effect.
3, Outcome measure
Effective: the Severe Asthma symptom complete incidence graph such as patient is uncomfortable in chest, chest pain, dyspnea, have mild episode once in a while only with mild such as coughs, do not need medication;
Effective: during patient's asthma attack, symptom obviously alleviates, and attack times also reduces to some extent;
Invalid: after medication, patient's symptoms of asthma is without alleviating.
4, therapeutic effect
Medication is after two weeks, and each group patient treatment situation is as following table:
Patient medication is after one week, and symptom is well alleviated, and within severe patient medication 2-3 month, can fully recover, patients with mild medication can be fully recovered for one month.Recovery from illness patient paid a return visit after 1 year, all without recurrence.

Claims (2)

1. treat a Chinese medicine composition for asthma, it is characterized in that being grouped into by the one-tenth of following weight portion: Folium Eriobotryae 20 parts, Radix Asteris 15 parts, 15 parts, Herba Ephedrae, Herba Taraxaci 10 parts, Flos Matricariae chamomillae 15 parts, Herba Pogostemonis 10 parts, Cortex Lycii 10 parts, 5 parts, Radix Glycyrrhizae, the Rhizoma Atractylodis Macrocephalae 10 parts, Margarita powder 1 part, Fructus Arctii 5 parts, Flos Bombacis Malabarici 1 part.
2. a preparation method for the Chinese medicine composition for the treatment of asthma according to claim 1, is characterized in that comprising: by mentioned component mix homogeneously, is ground into 80-120 object fine powder.
CN201410739940.2A 2013-09-26 2013-09-26 Medicine for treating asthma and preparation method thereof Withdrawn CN104352653A (en)

Priority Applications (1)

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CN201410739940.2A CN104352653A (en) 2013-09-26 2013-09-26 Medicine for treating asthma and preparation method thereof

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Application Number Priority Date Filing Date Title
CN201410739940.2A CN104352653A (en) 2013-09-26 2013-09-26 Medicine for treating asthma and preparation method thereof

Related Parent Applications (1)

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CN104352653A true CN104352653A (en) 2015-02-18

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Country Status (1)

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