CN111494482A - Traditional Chinese medicine composition for preventing and treating spring colds and preparation and application thereof - Google Patents
Traditional Chinese medicine composition for preventing and treating spring colds and preparation and application thereof Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition for preventing and treating spring colds, and a preparation and application thereof, wherein the active components of the traditional Chinese medicine composition comprise the following raw material medicines in parts by weight: 10-20 parts of astragalus membranaceus, 8-12 parts of bighead atractylodes rhizome, 8-12 parts of divaricate saposhnikovia root, 2-8 parts of honeysuckle, 4-6 parts of red paeony root, 2-8 parts of fortune eupatorium herb, 4-6 parts of dark plum fruit and 2-8 parts of liquorice. In the formula of the invention, the astragalus and the bighead atractylodes rhizome are used as monarch drugs together to strengthen the spleen and benefit the lung; radix sileris, radix paeoniae rubrathe and dark plum are used as ministerial drugs for nourishing the liver and softening the liver, honeysuckle and eupatorium are used for clearing heat and expelling damp, and liquorice is used as adjuvant drugs for harmonizing the effect of other drugs; has good prevention and treatment effect on the spring cold.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for preventing and treating spring colds, and a preparation and application thereof.
Background
Common cold is a common cold which is a common cold disease with the main clinical manifestations of lung-defense dysfunction, nasal obstruction, watery nasal discharge, sneezing, headache, aversion to cold, fever, general malaise, etc. caused by wind-evil or virus running in time. The air temperature changes greatly in spring, the resistance of the body can be reduced, the resistance of the mucous membranes of the nasal cavity and the oral cavity of a person can be reduced, the person is easy to catch cold, and the situation of repeated attack of the cold is easy to occur. However, the traditional Chinese medicine preparation for preventing cold has poor effect, and a traditional Chinese medicine composition is needed, so that the traditional Chinese medicine composition can effectively prevent the spring cold and reduce the spring cold times.
Disclosure of Invention
In view of the above, the invention provides a traditional Chinese medicine composition for preventing and treating spring colds, and a preparation and application thereof, and the traditional Chinese medicine composition has a good effect of preventing and treating spring colds.
The technical scheme of the invention is realized as follows: the active components of the traditional Chinese medicine composition for preventing and treating spring colds comprise the following raw material medicines in parts by weight: 10-20 parts of astragalus membranaceus, 8-12 parts of bighead atractylodes rhizome, 8-12 parts of divaricate saposhnikovia root, 2-8 parts of honeysuckle, 4-6 parts of red paeony root, 2-8 parts of fortune eupatorium herb, 4-6 parts of dark plum fruit and 2-8 parts of liquorice. Preferably, the active components of the traditional Chinese medicine composition comprise the following raw material medicines in parts by weight: 15 parts of astragalus, 10 parts of bighead atractylodes rhizome, 10 parts of divaricate saposhnikovia root, 5 parts of honeysuckle, 5 parts of red paeony root, 5 parts of fortune eupatorium herb, 5 parts of dark plum fruit and 5 parts of liquoric root.
Preferably, the active components of the traditional Chinese medicine composition further comprise the following raw material medicines in parts by weight: 5-15 parts of hispid fig, 2-8 parts of wrinkled gianthyssop herb and 5-15 parts of rhodiola rosea. More preferably, the active components of the traditional Chinese medicine composition further comprise the following raw material medicines in parts by weight: 10 parts of radix fici simplicissimae, 5 parts of wrinkled gianthyssop herb and 10 parts of rhodiola rosea.
A traditional Chinese medicine composition preparation for preventing and treating spring colds comprises the traditional Chinese medicine composition for preventing and treating spring colds, and the traditional Chinese medicine composition preparation is one of granules, decoction, pills, capsules and oral liquid.
The application of the traditional Chinese medicine composition in preparing the medicine for preventing and treating the spring cold is provided.
Compared with the prior art, the invention has the beneficial effects that:
in the formula of the invention, the astragalus and the bighead atractylodes rhizome are used as monarch drugs together to strengthen the spleen and benefit the lung; radix sileris, radix paeoniae rubrathe and dark plum are used as ministerial drugs for nourishing the liver and softening the liver, honeysuckle and eupatorium are used for clearing heat and expelling damp, and liquorice is used as adjuvant drugs for harmonizing the effect of other drugs; has the effects of strengthening spleen and lung, nourishing liver yin, strengthening body resistance, clearing lung heat, eliminating dampness and eliminating evil, and has good prevention and treatment effect on the spring cold. Moreover, on the basis of the formula, the radix fici simplicissimae, the wrinkled gianthyssop herb and the rhodiola rosea are added to strengthen the spleen, benefit the lung and eliminate dampness, and are used as adjuvant drugs together with the honeysuckle, the eupatorium and the liquorice; further improving the effect of preventing and treating the cold in spring.
Detailed Description
In order to better understand the technical content of the invention, specific examples are provided below to further illustrate the invention.
The experimental methods used in the examples of the present invention are all conventional methods unless otherwise specified.
The materials, reagents and the like used in the examples of the present invention can be obtained commercially without specific description.
The basic conditions of the main raw material drugs are described in the Chinese pharmacopoeia, the Chinese dictionary and the Chinese herbal medicine.
Astragalus root: [ PROPERTIES AND FLAVOUR ] sweet and warm. [ GUIJING ] enters lung and spleen meridians. [ FUNCTIONS ] can tonify qi, strengthen superficies, induce diuresis, remove toxicity, expel pus, heal wound and promote granulation. Can be used for treating deficiency of vital energy, asthenia, anorexia, loose stool, collapse of middle-warmer energy, chronic diarrhea, rectocele, hematochezia, metrorrhagia, superficial deficiency, spontaneous perspiration, qi deficiency, edema, carbuncle, cellulitis, intractable ulcer, blood deficiency, debility with yellowish complexion, internal heat, and diabetes; proteinuria due to chronic nephritis and diabetes.
White atractylodes rhizome: [ PROPERTIES AND WESTERN ] is bitter, sweet and warm. [ GUIJING ] can enter spleen and stomach meridians. [ FUNCTIONS ] can invigorate spleen, replenish qi, eliminate dampness, promote diuresis, stop sweating, and prevent miscarriage. Can be used for treating spleen deficiency, anorexia, abdominal distention, diarrhea, phlegm retention, dizziness, palpitation, edema, spontaneous perspiration, and threatened abortion.
Wind prevention: [ PROPERTIES AND FLAVOUR ] pungent, sweet and warm. [ GUIJING ] enters bladder, liver and spleen meridians. [ FUNCTIONS ] has effects in relieving exterior syndrome, expelling pathogenic wind, eliminating dampness, and relieving spasm. Can be used for treating common cold, headache, rheumatalgia, rubella, pruritus, and tetanus.
Honeysuckle flower: [ PROPERTIES AND FLAVOUR ] sweet and cold. [ GUIJING ] enters lung, heart and stomach meridians. [ FUNCTIONS ] can clear away heat and toxic materials, cool and dispel wind-heat. Can be used for treating carbuncle, furuncle, sore throat, erysipelas, toxic heat, dysentery, wind-heat type common cold, epidemic febrile disease, and fever.
Red peony root: [ PROPERTIES AND FLAVOUR ] bitter and slightly cold. [ GUIJING ] enters liver meridian. [ FUNCTIONS ] can clear heat and cool blood, remove blood stasis and relieve pain. Can be used for treating macula due to toxic heat, hematemesis, epistaxis, conjunctival congestion, swelling and pain, liver depression, hypochondriac pain, amenorrhea, dysmenorrhea, abdominal pain, traumatic injury, carbuncle, swelling, and pyocutaneous disease.
Herba Eupatorii: [ PROPERTIES AND FLAVOUR ] pungent and mild. [ GUIJING ] can enter spleen, stomach and lung meridians. [ FUNCTIONS ] can dispel dampness with aromatics, activate the spleen, stimulate the appetite, relieve exterior syndrome and relieve summer-heat. Can be used for treating damp stagnation, gastric fullness, emesis, halitosis, sialorrhea, summer-heat dampness, headache, and chest distress.
Dark plum: [ PROPERTIES AND FLAVOUR ] sour, astringent and neutral. [ GUIJING ] enters liver, spleen, lung and large intestine meridians. [ FUNCTIONS ] can astringe lung, astringe intestine, promote fluid production, and relieve ascaris. Can be used for treating lung deficiency, chronic cough, chronic dysentery, intestine dryness, asthenia heat, diabetes, ascariasis, emesis, abdominal pain, and biliary ascariasis.
Licorice root: [ PROPERTIES AND FLAVOUR ] sweet and neutral. [ GUIJING ] can enter heart, lung, spleen and stomach meridians. [ FUNCTIONS ] has effects in invigorating spleen, invigorating qi, clearing away heat and toxic materials, expelling phlegm, relieving cough, relieving spasm, relieving pain, and harmonizing the drugs. Can be used for treating weakness of spleen and stomach, asthenia, palpitation, short breath, cough, excessive phlegm, abdominal and limb spasm, pain, carbuncle, swelling, sore, and drug toxicity and strong nature.
Radix fici simplicissimae: [ PROPERTIES AND FLAVOUR ] sweet and slightly warm. [ GUIJING ] enters spleen, lung and liver meridians. [ FUNCTIONS INDICATIONS ] can invigorate spleen, eliminate dampness, promote the circulation of qi, resolve phlegm, relax tendons, activate collaterals. Can be used for treating pulmonary tuberculosis cough, chronic bronchitis, rheumatic arthritis, lumbago, skelalgia, spleen deficiency, edema, night sweat, and leucorrhea.
Agastache rugosus: [ PROPERTIES AND FLAVOUR ] pungent and slightly warm. [ GUIJING ] enters lung, spleen and stomach meridians. [ FUNCTIONS ] can promote the flow of qi, regulate the middle warmer, remove dirt, and eliminate dampness. It is used to treat common cold with summer-heat and dampness, cold and heat, headache, fullness and distention in chest and abdomen, emesis, diarrhea, malaria, dysentery, and halitosis.
Rhodiola root: [ PROPERTIES AND FLAVOURS ] COLD; sweet; astringent. [ GUIJING ] Lung meridian. [ FUNCTIONAL INDICATIONS ] BU-QI and CLEANING HEART-FIRED MEDICINE; benefiting intelligence and nourishing heart; astringing to stop bleeding; dispel stasis and relieve swelling. Deficiency of vital energy and physical weakness; aversion to cold after illness; shortness of breath and lack of strength; cough due to lung heat; hemoptysis; leucorrhea and diarrhea; traumatic injury; scald and burn; neuropathy; altitude reaction.
Example 1
A traditional Chinese medicine composition for preventing and treating spring colds comprises the following active components by weight: 10g of astragalus, 12g of fried bighead atractylodes rhizome, 12g of divaricate saposhnikovia root, 2g of honeysuckle, 6g of red paeony root, 2g of fortune eupatorium herb, 4g of dark plum and 2g of honey-fried licorice root. Making into Chinese medicinal granule by conventional method.
Example 2
A traditional Chinese medicine composition for preventing and treating spring colds comprises the following active components by weight: 20g of astragalus, 8g of fried bighead atractylodes rhizome, 8g of divaricate saposhnikovia root, 8g of honeysuckle, 4g of red paeony root, 8g of fortune eupatorium herb, 6g of dark plum fruit and 8g of honey-fried licorice root. Making into Chinese medicinal granule by conventional method.
Example 3
A traditional Chinese medicine composition for preventing and treating spring colds comprises the following active components by weight: 15g of astragalus, 10g of fried bighead atractylodes rhizome, 10g of divaricate saposhnikovia root, 5g of honeysuckle, 5g of red paeony root, 5g of fortune eupatorium herb, 5g of dark plum and 5g of honey-fried licorice root. Making into Chinese medicinal granule by conventional method.
Example 4
The embodiment of the traditional Chinese medicine composition is different from the embodiment 1 in that hispid fig, wrinkled gianthyssop herb and rhodiola rosea are added. The active components of the traditional Chinese medicine composition comprise the following raw material medicines by weight: 10g of astragalus, 12g of fried bighead atractylodes rhizome, 12g of divaricate saposhnikovia root, 2g of honeysuckle, 6g of red paeony root, 2g of fortune eupatorium herb, 4g of dark plum, 2g of honey-fried licorice root, 5g of hispid fig, 8g of wrinkled gianthyssop herb and 15g of rhodiola rosea. Making into Chinese medicinal granule by conventional method.
Example 5
The embodiment of the traditional Chinese medicine composition is different from the embodiment 2 in that hispid fig, wrinkled gianthyssop herb and rhodiola rosea are added. The active components of the traditional Chinese medicine composition comprise the following raw material medicines by weight: 20g of astragalus membranaceus, 8g of fried bighead atractylodes rhizome, 8g of divaricate saposhnikovia root, 8g of honeysuckle, 4g of red paeony root, 8g of fortune eupatorium herb, 6g of dark plum, 8g of honey-fried licorice root, 15g of hispid fig, 2g of wrinkled gianthyssop herb and 5g of rhodiola rosea. Making into Chinese medicinal granule by conventional method.
Example 6
The embodiment of the traditional Chinese medicine composition is different from the embodiment 3 in that hispid fig, wrinkled gianthyssop herb and rhodiola rosea are added. The active components of the traditional Chinese medicine composition comprise the following raw material medicines by weight: 15g of astragalus, 10g of fried bighead atractylodes rhizome, 10g of divaricate saposhnikovia root, 5g of honeysuckle, 5g of red paeony root, 5g of fortune eupatorium herb, 5g of dark plum, 5g of honey-fried licorice root, 10g of hispid fig root, 5g of wrinkled gianthyssop herb and 10g of rhodiola rosea. Making into Chinese medicinal granule by conventional method.
The traditional Chinese medicine granules prepared by the embodiments are applied to clinic:
1. basic data: the patients who had cold more than 6 times in the spring of the last 1 year were collected for a total of 360 cases. The collected cases meet the diagnosis standard of traditional Chinese medicine syndrome, refer to "internal medicine of traditional Chinese medicine" for treating cold ", and simultaneously meet the diagnosis standard of common cold of" practical internal medicine "of western medicine. The age is 18-55 years. The test groups are randomly grouped, namely test group 1 to test group 6, and each group comprises 60 cases. The gender distribution, mean age for each group are shown in the following table:
the patients in each group have no statistical difference in age, sex and the like and are comparable.
2. The treatment method and the treatment course are as follows: the test groups 1 to 6 respectively correspond to the use of the traditional Chinese medicine composition granules in the embodiments 1 to 6, 1 dose is taken every day with boiled water, 7 days is a treatment course, and 4 treatment courses are continuously taken.
3. Criteria for judging therapeutic effects
And (3) curing: the cold does not occur in spring in the same year, and no cold occurs in follow-up visit after half a year.
The method has the following advantages: the number of cold is reduced, and the cold symptom is relieved.
And (4) invalidation: the cold frequency is not reduced, and the cold symptoms are not improved.
4. Therapeutic results
The clinical situations show that the traditional Chinese medicine composition disclosed by the embodiments 1-6 of the invention has an obvious treatment effect on preventing and treating the spring cold, the cure rate is over 75.0%, and the total effective rate is over 98.3%.
5. Typical cases
Medical record 1: zhangyi, female, 36 years old, first diagnosis in 2018, 2 and 26 days, self-complaint and susceptibility to common cold, common cold once per month, obvious spring, common cold more than 6 times in the last 1 year, aversion to wind and sweating at ordinary times, after 1 treatment course of continuous taking of the traditional Chinese medicine granules in the embodiment 3 of the invention, symptoms of aversion to wind and sweating are obviously relieved, the symptoms of aversion to wind and sweating disappear after 3 treatment courses of continuous taking, common cold does not appear during the taking period, follow-up after 3 months, and cold does not exist in Zhangyi whole spring. There was no cold in follow-up visit after half a year.
Medical record 2: when a woman is diagnosed in 45 years old in 2018 and in 28 months, the medicine is weak, is afraid of wind and cold, is easy to catch cold, is obvious in spring, can produce watery nasal discharge and sneeze when being slightly windy and is cooled, and can catch cold for more than 6 times in the last 1 year spring, after the traditional Chinese medicine granule in the embodiment 6 of the invention is continuously taken for 1 treatment course, the traditional Chinese medicine granule is weak, is afraid of wind and cold better, is continuously taken for 3 treatment courses, and does not have the weak and the afraid of wind and cold after being taken, and can not produce watery nasal discharge and sneeze even if being windy and cooled. During the administration period, no common cold appears, and after 3 months, the follow-up visit is carried out, and the plum has no common cold in a certain whole spring. There was no cold in follow-up visit after half a year.
6. And (4) safety observation: in all treatment observations, no adverse events were observed.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (6)
1. The traditional Chinese medicine composition for preventing and treating spring colds is characterized by comprising the following active components in parts by weight: 10-20 parts of astragalus membranaceus, 8-12 parts of bighead atractylodes rhizome, 8-12 parts of divaricate saposhnikovia root, 2-8 parts of honeysuckle, 4-6 parts of red paeony root, 2-8 parts of fortune eupatorium herb, 4-6 parts of dark plum fruit and 2-8 parts of liquorice.
2. The traditional Chinese medicine composition for preventing and treating spring colds according to claim 1, which is characterized by comprising the following active components in parts by weight: 15 parts of astragalus, 10 parts of bighead atractylodes rhizome, 10 parts of divaricate saposhnikovia root, 5 parts of honeysuckle, 5 parts of red paeony root, 5 parts of fortune eupatorium herb, 5 parts of dark plum fruit and 5 parts of liquoric root.
3. The traditional Chinese medicine composition for preventing and treating spring colds according to claim 1, which is characterized by further comprising the following raw material medicines in parts by weight: 5-15 parts of hispid fig, 2-8 parts of wrinkled gianthyssop herb and 5-15 parts of rhodiola rosea.
4. The traditional Chinese medicine composition for preventing and treating spring colds according to claim 2, which is characterized by further comprising the following raw material medicines in parts by weight: 10 parts of radix fici simplicissimae, 5 parts of wrinkled gianthyssop herb and 10 parts of rhodiola rosea.
5. A traditional Chinese medicine composition preparation for preventing and treating spring colds, which is characterized by comprising the traditional Chinese medicine composition of any one of claims 1 to 4, and the traditional Chinese medicine composition preparation is one of granules, decoction, pills, capsules and oral liquid.
6. The use of the Chinese medicinal composition of any one of claims 1 to 4 in the preparation of a medicament for preventing and treating spring colds.
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CN202010466386.0A CN111494482B (en) | 2020-05-28 | 2020-05-28 | Traditional Chinese medicine composition for preventing and treating spring colds and preparation and application thereof |
PCT/CN2021/094061 WO2021238695A1 (en) | 2020-05-28 | 2021-05-17 | Traditional chinese medicine composition for preventing and treating cold in spring and granules and application thereof |
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WO2021238695A1 (en) * | 2020-05-28 | 2021-12-02 | 程亚伟 | Traditional chinese medicine composition for preventing and treating cold in spring and granules and application thereof |
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CN1253796A (en) * | 1998-11-18 | 2000-05-24 | 陈江辉 | Ganmaojing ointment for curing common cold and its preparation method |
CN1315189A (en) * | 2000-03-30 | 2001-10-03 | 陈江辉 | Tea for treating cold and its preparing process |
CN102133336A (en) * | 2010-01-21 | 2011-07-27 | 常州善美药物研究开发中心有限公司 | Traditional Chinese medicine composite, and preparation method and application thereof |
CN104367632A (en) * | 2014-11-21 | 2015-02-25 | 范影 | Small prescription for treating cold |
CN106309541A (en) * | 2015-06-26 | 2017-01-11 | 孙惠红 | Traditional Chinese medicine composition for prevention and treatment of susceptible-to-cold physique |
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CN1064842C (en) * | 1995-12-07 | 2001-04-25 | 青岛市海慈医疗集团海慈医院 | Jade-supplementing bagged medicinal preparation and its prepn. method |
CN111494482B (en) * | 2020-05-28 | 2023-01-20 | 程亚伟 | Traditional Chinese medicine composition for preventing and treating spring colds and preparation and application thereof |
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Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1253796A (en) * | 1998-11-18 | 2000-05-24 | 陈江辉 | Ganmaojing ointment for curing common cold and its preparation method |
CN1315189A (en) * | 2000-03-30 | 2001-10-03 | 陈江辉 | Tea for treating cold and its preparing process |
CN102133336A (en) * | 2010-01-21 | 2011-07-27 | 常州善美药物研究开发中心有限公司 | Traditional Chinese medicine composite, and preparation method and application thereof |
CN104367632A (en) * | 2014-11-21 | 2015-02-25 | 范影 | Small prescription for treating cold |
CN106309541A (en) * | 2015-06-26 | 2017-01-11 | 孙惠红 | Traditional Chinese medicine composition for prevention and treatment of susceptible-to-cold physique |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2021238695A1 (en) * | 2020-05-28 | 2021-12-02 | 程亚伟 | Traditional chinese medicine composition for preventing and treating cold in spring and granules and application thereof |
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