CN104342351A - Health liquor - Google Patents

Health liquor Download PDF

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Publication number
CN104342351A
CN104342351A CN201410586008.0A CN201410586008A CN104342351A CN 104342351 A CN104342351 A CN 104342351A CN 201410586008 A CN201410586008 A CN 201410586008A CN 104342351 A CN104342351 A CN 104342351A
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China
Prior art keywords
wine
wine base
root
liquor
base
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Pending
Application number
CN201410586008.0A
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Chinese (zh)
Inventor
梁仲军
邓育萍
杨晓明
李忠国
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GANSU PHARMACEUTICAL RESEARCH INSTITUTE
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GANSU PHARMACEUTICAL RESEARCH INSTITUTE
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Priority to CN201410586008.0A priority Critical patent/CN104342351A/en
Publication of CN104342351A publication Critical patent/CN104342351A/en
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/04Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/616Echinodermata, e.g. starfish, sea cucumbers or sea urchins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/87Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to health liquor. The health liquor is brewed through compatibility of 5kg of sorghum liquor serving as a yin and yang liquor base and the following components: 30-45g of lotus seeds, 50-65g of honeysuckle, 30-45g of salvia miltiorrhiza, 10-25g of potentilla anserina, one sea cucumber, 10-25g of barbary wolfberry fruit, 30-45g of kudzuvine root, 250-270g of raisins, 10-15g of hawthorns, 10-15g of thunberg fritillary bulb, 10-15g of dwarf lilyturf tuber, 20-35g of polygoni multiflori preparata and 50-65g of white sesames. The invention also discloses a preparation method of the health liquor. The health liquor has the functions of warming the channels to remove coldness, dispelling dampness to relieve pain, strengthening tendons and bones and tonifying the liver and kidneys, and is safe to drink.

Description

A kind of health preserving wine
Technical field
The present invention relates to health promoting wine technical field, particularly relate to a kind of health preserving wine.
Background technology
The medicinal liquor that existing market is sold generally selects the number of degrees to be that the common grain wine of about 50 degree is as wine base, just pour into by crude drug dedusting, removal of impurities or after making partially disposed in brew process, stir, seal up for safekeeping, and brewed wine used be there is no do any process.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of health preserving wine with reinforcing spleen and kidney function.
For solving the problem, a kind of health preserving wine of the present invention, it is characterized in that: it is using 5kg Kaoliang spirit as negative and positive wine base, and following group of compatibility is brewed forms: lotus seeds 30 ~ 45g, Japanese Honeysuckle 50 ~ 65g, the red sage root 30 ~ 45g, fern fiber crops 10 ~ 25g, sea cucumber 1, matrimony vine 10 ~ 25g, the root of kudzu vine 30 ~ 45g, raisin 250 ~ 270g, hawthorn 10 ~ 15g, Thunberg Fritillary Bulb 10 ~ 15g, the tuber of dwarf lilyturf 10 ~ 15g, Radix Polygoni Multiflori Preparata 20 ~ 35g, white sesame 50 ~ 65g.
The production method of a kind of health preserving wine as above, comprises the following steps:
(1) weigh by proportioning;
(2), by after lotus seeds, Japanese Honeysuckle, the red sage root, fern fiber crops, sea cucumber, matrimony vine, the root of kudzu vine, raisin, hawthorn, Thunberg Fritillary Bulb, the tuber of dwarf lilyturf, Radix Polygoni Multiflori Preparata, white sesame mixing, dry through rinsing, drenching, spreading for cooling under room temperature, obtains mixture;
(3) by 5kg alcoholic strength be 59% Kaoliang spirit be divided into two, wherein 2.5kg heated and boiled 100 ~ 120min makes positive wine base, and all the other 2.5kg are directly as cloudy wine base;
(4) pour described cloudy wine base into wine jar, then described mixture is poured in described cloudy wine base at normal temperatures, stir; After 100 ~ 120min, described positive wine base is poured in described wine jar, stirs, seal preservation at normal temperatures, within every 3 days, stir once, 5 times repeatedly, preserve after one month, after filtration, filling.
The present invention compared with prior art has the following advantages:
1, the present invention select alcoholic strength be the Kaoliang spirit of 59% as former wine, first the former wine heated and boiled 100 ~ 120min of half is made positive wine base, residue half does not heat as cloudy wine base for subsequent use, and prior art there is no saying of negative and positive wine base.
2, the present invention just processed the former wine concocted before medicinal material does not also enter altar, not only make the wine after heating more effectively can kill the germ and harmful microorganism that attach in Chinese medicinal herbs in immersion process, parasite and worm's ovum, obviously increase the safety coefficient of concocted medicinal liquor, and the negative and positive wine base after process, the performance of wine is gentleer, stable, concoct to make after medicinal material whole medicinal liquor focus on negative and positive complementation peace and, enriching yin and oiliness, establishing-Yang and not dry, without the sorrow of inclined merit, there is gentle U.S., kidney can be supported by warm spleen, thus play warming channel and expelling cold, damp-clearing pain-relieving, strengthening the muscles and bones, the effect tonified the liver and kidney.
3, the present invention shows through toxicity test, can drink safely.
[ test materials]
(1) trial drug:
Concentrated extract of the present invention, chocolate, 1g thick paste is equivalent to 28.15ml medicinal liquor, and relative density is 1.33g/ml.Made by Gansu Pharmaceutical Reaearch Institute and provide.
(2) experimental animal:
KM mouse, SPF level, male and female dual-purpose, body weight 18 ~ 22g, is provided by Gansu Chinese of Traditional Chinese Medicine's scientific experiment center, animal facility use certificate SYXK (sweet) 2013-0001, Quality of Experimental Animals conformity certification SCXK (sweet) 2013-0001, Science and Technology Department of Gansu Province of issuing unit.
Animal is by sex sub-cage rearing, and 5/cage, food SPF level solid feed, freely, feed is provided by the section of providing of laboratory animal feed corporation,Ltd that pulls together of Beijing Australia of section drinking water, room temperature 20 ~ 25 DEG C, relative humidity 45% ~ 52%.
[ test method and result]
(1) test prerun:
Mouse 18, ♀ ♂ half and half, be divided into 3 groups at random, often organize 6, fasting is after 12 hours, 0.4ml thick paste/10g body weight (53.2g/kg is given respectively according to gavage, 1498ml/kg), 0.2ml thick paste/10g body weight (26.6g/kg, 749ml/kg), 0.1g thick paste/10g body weight (13.3g/kg, 374.5ml/kg), 2 times on the one, interval 6h.Result is without dead mouse, and prompting does not measure LD 50, therefore measure mouse maximum dosage-feeding on the one.
(2) official test:
Separately get mouse 40, ♀ ♂ half and half, fasting is after 12 hours, and gavage gives this wine peak concentration medicinal extract 0.4ml/10g(53.2g/kg, 1498ml/kg), 2 times on the one, interval 6h.One-way analysis of variance process is carried out, in table 1 to the body weight change result statistic software SPSS 13.0 of animal.Diet, outward appearance, behavior, secretory product, movement, death condition are in table 2.
The change of table 1 acute toxicity test Mouse Weight (unit: g, n=10, x ± SD)
Note: compare with control group, P>0.05.
Result shows, administration group of the present invention and control group mice body weight gain aspect population mean do not have difference.
Table 2 day maximum dosage-feeding test mice response situation
Note :-representative is normal.
Result shows, viewing duration mouse hair gloss, and freely, feed and stool, urine normally, find no other toxic reactions in activity.In 14 days, the weight of animals increases, and is increased to 31.1 ± 1.5g by testing front 19.4 ± 1.0g, and none is only dead.At the end of experiment, cervical dislocation puts to death mouse, dissects visual inspection main organs color and morphological change, and the main organs no abnormality seens such as the result heart, liver, spleen, lung, kidney, stomach, intestines change.Accordingly, mouse stomach administration of the present invention maximum dosage-feeding on the one is that 0.8ml medicinal extract/10g(is equivalent to 80ml medicinal extract/kg, or 106g medicinal extract/kg, or the former wine of 2996ml), have no obvious acute toxic reaction.
[ conclusion (of pressure testing)]
After mouse stomach administration of the present invention, do not find obvious acute toxicity, mouse maximum dosage-feeding on the one is 80ml medicinal extract/kg, or 106g medicinal extract/kg, or the former wine of 2996ml/kg, is equivalent to 2097 times of the every daily dosage portion of clinical adult (100ml/70kg).
4, preparation method of the present invention is simple, easy to implement.
Embodiment
embodiment 1a kind of health preserving wine, it is using 5kg Kaoliang spirit as negative and positive wine base, and the following component of compatibility is brewed forms: lotus seeds 30g, Japanese Honeysuckle 50g, red sage root 30g, fern fiber crops 10g, sea cucumber 1, matrimony vine 10g, root of kudzu vine 30g, raisin 250g, hawthorn 10g, Thunberg Fritillary Bulb 10g, the tuber of dwarf lilyturf 10 ~ 15g, Radix Polygoni Multiflori Preparata 20g, white sesame 50g.
The production method of this health preserving wine, comprises the following steps:
(1) weigh by proportioning;
(2), by after lotus seeds, Japanese Honeysuckle, the red sage root, fern fiber crops, sea cucumber, matrimony vine, the root of kudzu vine, raisin, hawthorn, Thunberg Fritillary Bulb, the tuber of dwarf lilyturf, Radix Polygoni Multiflori Preparata, white sesame mixing, dry through rinsing, drenching, spreading for cooling under room temperature, obtains mixture;
(3) by 5kg alcoholic strength be 59% Kaoliang spirit be divided into two, wherein 2.5kg heated and boiled 100 ~ 120min makes positive wine base, and all the other 2.5kg are directly as cloudy wine base;
(4) pour cloudy wine base into wine jar, then mixture is poured in cloudy wine base at normal temperatures, stir; After 100 ~ 120min, positive wine base is poured in wine jar, stirs, seal preservation at normal temperatures, within every 3 days, stir once, 5 times repeatedly, preserve after one month, after filtration, filling.
embodiment 2a kind of health preserving wine, it is using 5kg Kaoliang spirit as negative and positive wine base, and the following component of compatibility is brewed forms: lotus seeds 45g, Japanese Honeysuckle 65g, red sage root 45g, fern fiber crops 25g, sea cucumber 1, matrimony vine 25g, root of kudzu vine 45g, raisin 270g, hawthorn 15g, Thunberg Fritillary Bulb 15g, the tuber of dwarf lilyturf 15g, Radix Polygoni Multiflori Preparata 35g, white sesame 65g.
The production method of this health preserving wine is same embodiment 1.
embodiment 3a kind of health preserving wine, it is using 5kg Kaoliang spirit as negative and positive wine base, and the following component of compatibility is brewed forms: lotus seeds 35g, Japanese Honeysuckle 55g, red sage root 35g, fern fiber crops 15g, sea cucumber 1, matrimony vine 15g, root of kudzu vine 35g, raisin 260g, hawthorn 12g, Thunberg Fritillary Bulb 12g, the tuber of dwarf lilyturf 12g, Radix Polygoni Multiflori Preparata 20 ~ 35g, white sesame 50 ~ 65g.
The production method of this health preserving wine is same embodiment 1.
embodiment 4a kind of health preserving wine, it is using 5kg Kaoliang spirit as negative and positive wine base, and the following component of compatibility is brewed forms: lotus seeds 40g, Japanese Honeysuckle 60g, red sage root 40g, fern fiber crops 20g, sea cucumber 1, matrimony vine 20g, root of kudzu vine 40g, raisin 255g, hawthorn 14g, Thunberg Fritillary Bulb 14g, the tuber of dwarf lilyturf 14g, Radix Polygoni Multiflori Preparata 20 ~ 35g, white sesame 50 ~ 65g.
The production method of this health preserving wine is same embodiment 1.

Claims (2)

1. a health preserving wine, it is characterized in that: it is using 5kg Kaoliang spirit as negative and positive wine base, and the following component of compatibility is brewed forms: lotus seeds 30 ~ 45g, Japanese Honeysuckle 50 ~ 65g, the red sage root 30 ~ 45g, fern fiber crops 10 ~ 25g, sea cucumber 1, matrimony vine 10 ~ 25g, the root of kudzu vine 30 ~ 45g, raisin 250 ~ 270g, hawthorn 10 ~ 15g, Thunberg Fritillary Bulb 10 ~ 15g, the tuber of dwarf lilyturf 10 ~ 15g, Radix Polygoni Multiflori Preparata 20 ~ 35g, white sesame 50 ~ 65g.
2. the production method of a kind of health preserving wine as claimed in claim 1, comprises the following steps:
(1) weigh by proportioning;
(2), by after lotus seeds, Japanese Honeysuckle, the red sage root, fern fiber crops, sea cucumber, matrimony vine, the root of kudzu vine, raisin, hawthorn, Thunberg Fritillary Bulb, the tuber of dwarf lilyturf, Radix Polygoni Multiflori Preparata, white sesame mixing, dry through rinsing, drenching, spreading for cooling under room temperature, obtains mixture;
(3) by 5kg alcoholic strength be 59% Kaoliang spirit be divided into two, wherein 2.5kg heated and boiled 100 ~ 120min makes positive wine base, and all the other 2.5kg are directly as cloudy wine base;
(4) pour described cloudy wine base into wine jar, then described mixture is poured in described cloudy wine base at normal temperatures, stir; After 100 ~ 120min, described positive wine base is poured in described wine jar, stirs, seal preservation at normal temperatures, within every 3 days, stir once, 5 times repeatedly, preserve after one month, after filtration, filling.
CN201410586008.0A 2014-10-28 2014-10-28 Health liquor Pending CN104342351A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1373193A (en) * 2001-03-07 2002-10-09 陈列 Process for preparing health-care arborvitae seed-Chinese angelica root liquor
CN101041005A (en) * 2006-03-20 2007-09-26 金林海 Health-care wine and its preparing method
CN101612327A (en) * 2009-07-20 2009-12-30 朱园奎 A kind of health promoting wine and preparation method thereof
KR20130077397A (en) * 2011-12-29 2013-07-09 시흥시 A manufacturing method of rice wine made from lotus leaf
CN103289873A (en) * 2013-03-13 2013-09-11 甘肃省药物研究院 Health care wine and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1373193A (en) * 2001-03-07 2002-10-09 陈列 Process for preparing health-care arborvitae seed-Chinese angelica root liquor
CN101041005A (en) * 2006-03-20 2007-09-26 金林海 Health-care wine and its preparing method
CN101612327A (en) * 2009-07-20 2009-12-30 朱园奎 A kind of health promoting wine and preparation method thereof
KR20130077397A (en) * 2011-12-29 2013-07-09 시흥시 A manufacturing method of rice wine made from lotus leaf
CN103289873A (en) * 2013-03-13 2013-09-11 甘肃省药物研究院 Health care wine and preparation method thereof

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