CN104338040A - Traditional Chinese medicine for treating chronic pneumonia - Google Patents
Traditional Chinese medicine for treating chronic pneumonia Download PDFInfo
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- CN104338040A CN104338040A CN201410623268.0A CN201410623268A CN104338040A CN 104338040 A CN104338040 A CN 104338040A CN 201410623268 A CN201410623268 A CN 201410623268A CN 104338040 A CN104338040 A CN 104338040A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/428—Trichosanthes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
Abstract
The invention relates to a traditional Chinese medicine for treating chronic pneumonia. The traditional Chinese medicine is prepared by using following raw materials in parts by weight: 5 parts of schizonepeta, 8 parts of tabasheer, 6 parts of cynanchum glaucescens, 10 parts of trichosanthes kirilowii maxim, 25 parts of oreocharis maximowiczii clarke and 9 parts of semen lepidii. Clinical experiments prove that the traditional Chinese medicine can be used for safely and effectively treating the chronic pneumonia.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of chronic pneumonia.
Background technology
Pneumonia refers to the inflammation of last air flue, alveolar and interstitial lung eventually, and the course of disease is chronic pneumonia more than 3 months persons.Can by pathogenic microorganism such as antibacterial, virus, fungus, parasites, and the chemical factors such as lonizing radiation, imbedibility foreign body causes.Clinical manifestation is suddenly shiver with cold, high heat, body temperature up to 39 DEG C ~ 40 DEG C, in delaying pattern of fever, poor appetite aching and limp with headache, whole-body muscle; Early stage be zest dry cough, then brings up white mucus expectorant or band sputum with blood streaks, and after 1 ~ 2 day, can bring up mucus courageous and upright expectorant, rusty expectoration, purulent sputum, the phase amount of expectoration that dissipates increases, expectorant Huang and thin; Often there is violent chest pain, in acupuncture sample, increase the weight of with cough or deep breathing, can to shoulder or abdominal part radiation; Because of pulmonary consolidation cause hypoventilation, gas interchange disturbance, arterial oxygen saturation reduce and there is cyanosis, chest pain, dyspnea; Minority has the gastrointestinal symptoms such as Nausea and vomiting, abdominal distention or diarrhoea, can occur in a certain state of delirium, irritated, drowsiness during serious symptom, and suffocating even appears in severe one, stupor etc.
Primary disease any age all can fall ill, and acute pneumonia is treated timely will be recurred, and becomes chronic pneumonia for a long time.The touching difficulty of the primary disease course of disease more, finally may cause pulmonary carcinoma.
The chronic pneumonia course of disease comparatively refractory repeatedly, its morbidity mostly is the infection such as antibacterial, virus, current western medicine has fluorine promise ketone, second/third-generation cephalosporin, beta-lactam/beta-lactamase inhibitor, or ertapenem, the antibiotic such as vinegar class in macro ring can be combined, adrenocortical hormone, prednisone etc., but its treatment is all easily developed immunity to drugs and side effect is larger.
Primary disease belongs to the category such as the traditional Chinese medical science " pathogenic wind-warm ", " cough ", " pyretic pulmonary disease " according to its clinical manifestation, similar with " lung-QI stagnation syndrome ", " breathe heavily and cough " etc.
Medical material present Research involved in the present invention is as follows:
Herba Schizonepetae [source] this product is the dry aerial parts of labiate Herba Schizonepetae (Schizonepeta tenuifolia Briq.).Summer, season in autumn two, the flowers are in blossom to top, fringe green time tap, removing impurity, dry.[nature and flavor] are pungent, tepor.[return through] returns lung, Liver Channel.[function cures mainly] induces sweat loose wind, rash.For flu, headache, measles, rubella, skin infection from the beginning of.Parch to black treating hematochezia, metrorrhagia, puerperal blood faints.[usage and dosage] 4.5 ~ 9g.
Concretio Silicea Bambusae [source] this product is the dried block of juice in the bar such as grass Chinese textile bamboo (Bambusa textilis McClure) or schizostachyum chinense Rendle (Schizostachyum chinense Rendle).Autumn, season in winter two gather.[nature and flavor] are sweet, cold.[return through] GUIXIN, Liver Channel.[function cures mainly] clear heat and eliminate phlegm, cool heart arresting convulsion.For calentura coma, middle wind-phlegm fan, the hot infantile convulsion of children's's expectorant, tic, night cry.[usage and dosage] 3 ~ 9g.
Rhizoma Cynanchi Stauntonii [source] this product is the root and rhizome of dicotyledon medicine asclepiadaceae plant rhizoma et radix cynanchi stauntoni or leaves of Daphne genkwa Rhizoma Cynanchi Stauntonii.Take Herb after autumn, root and rhizome is adopted down, clean, dry or dry.[nature and flavor] are pungent, sweet, tepor.[return through] returns lung meridian.[function cures mainly] eliminating the pathogens from the lung sending down the abnormal ascending QI, lower expectorant antitussive.Main smelting lung qi stops up the cough with copious phlegm of reality, dyspnea due to adverseness of QI; Gastralgia, youngster's infantile malnutrition; Traumatic injury.[usage and dosage] 3 ~ 10g.
Fructus Trichosanthis [source] this product is the dry mature fruit of cucurbitaceous plant Fructus Trichosanthis (Trichosanthes kirilowii Maxim.) or trichosanthes rosthornii Harms (Trichosan-thes rosthornii Harms).During fruit maturation in autumn, connect carpopodium and cut, put ventilation and dry in the shade.[nature and flavor] sweet, micro-hardship, cold.[return through] returns lung, stomach, large intestine channel.[function cures mainly] clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizes laxation.For cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, lung abscess, and acute appendicitis swells and ache, constipation.[usage and dosage] 9 ~ 15g.
Lotus Begonia bretschneideriana Hemsl. on Shi Shanglian [source] Begoniaceae stone, with all herbal medicine.[nature and flavor] are sour, micro-puckery, cool.[function cures mainly] removing damp-heat, diuretic softening the hard mass, reducing swelling and alleviating pain.Treating hepatocirrhosis, ascites, summer-heat is thirsty.Treating swelling and pain by traumatic injury is controlled in external, furuncle swelling toxin.[usage and dosage] 25 ~ 50g.
Semen Lepidii (Semen Descurainiae) [source] this product is the dry mature seed of crucifer Lepidium sativum L. (Lepidium apetalum Willd.) or descurainia sophia (l.) webb ex prantl (Descurainia sophia Webb ex prantl).Tap plant during fruit maturation in summer, dry, rub seed, removing impurity.[nature and flavor] are pungent, bitter, Great Cold.[return through] returns lung, urinary bladder channel.[function cures mainly] eliminating pathogen from the lung for relieving asthma, line water detumescence.Stop up lung for sputum, dyspnea and cough with excessive sputum, fullness and distention in the chest and hypochondrium, must not put down sleeping, and ascites pleural fluid swells, dysuria; Pulmonary heart disease edema.[usage and dosage] 3 ~ 9g.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of chronic pneumonia, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing chronic pneumonia.
In order to achieve the above object, the present invention is by the following technical solutions:
Be used for the treatment of a Chinese medicine for chronic pneumonia, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: 25 parts, lotus, Semen Lepidii (Semen Descurainiae) 9 parts on Herba Schizonepetae 5 parts, Concretio Silicea Bambusae 8 parts, Rhizoma Cynanchi Stauntonii 6 parts, Fructus Trichosanthis 10 parts, stone.
Inventor thinks that the cause of disease of pneumonia often betides overstrain, and when the human righteousness such as wind are not enough after liquor-saturated, table is experienced the heresy of wind heat or the heresy of wind and cold, entered caused by inner heat-transformation when defending and not consolidating.Pathological change is positive QI-insufficiency, table Wei Bugu, and can not drive evil in outward, evil impairing the lung is defended, and ailment said due to cold or exposure bundle table, defends the stagnation of QI and close, and see fever with aversion to cold; Block of lung-QI, loses a surname Yu and reaches and cough; Lung is cloth Tianjin not, gathers and is expectorant, and hindering in cold-evil is then white rare expectorant, hinders and then sees white glutinous expectorant or yellow sputum in pathogenic heat or cold-evil's heat-transformation.Pathogen retardance lung network, can cause chest pain, contain in pathogenic heat. lung network of burning, spit blood as seen.If pathogen crosses Sheng, vital QI cannot conquer pathogen, pathogen entering the interior, interior biography nutrient blood, very then pathogenic heat are caved in, the pathogen attacking the pericardium adversely, can cause Kidney-Yin for exhausting, and yang-energy is collapsed, and send out as primary disease.Treatment should with heat radiation of inducing sweat, act as expectorant, eliminating pathogen from the lung for relieving asthma is basic, therefore assembly is our.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and chronic pneumonia patient 30 example of being in hospital altogether in inventor in July, 2010 ~ 2013 between year March, be divided into treatment group 15 example and matched group 15 example at random, treatment group man 8 example, female 7 example, 34 ~ 58 years old age, 40.3 years old mean age, the course of disease 1 ~ 2 year; Matched group man 6 example, female 9 example, 30 ~ 62 years old age, 44.9 years old mean age, the course of disease 1 ~ 3 year.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
1) pneumonia, through antibacterial drug therapy after 4 weeks, chest x-ray is pointed out: pulmonary infection/inflammation is complete absorber not yet; 2) cough, cough up phlegm, abdominal distention, loose stool, the symptoms such as fatigue and weakness; 3) get rid of pneumonia person caused by non-infective agent as pulmonary carcinoma etc., get rid of cough caused, the person of coughing up phlegm of infectious disease as pulmonary tuberculosis etc.Possess above-mentioned 3 persons and can make a definite diagnosis primary disease.
2, test method
2.1 Therapeutic Method
The decoct that the oral the present invention for the treatment of group obtains according to specific embodiment 1, every day 3 times.4 weeks courses for the treatment of.
Matched group Administration of roxithromycin sheet (Liaoning Bei Qi pharmaceutcal corporation, Ltd), takes according to its description.4 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Clinical cure: chest x-ray prompting pulmonary infection/inflammation absorbs completely, and uncomfortable symptom disappears completely;
Effective: chest x-ray prompting pulmonary infection/inflammatory components absorbs, and uncomfortable symptom is alleviated to some extent;
Invalid: chest x-ray prompting pulmonary infection/inflammation does not absorb, and uncomfortable symptom is not alleviated even increase the weight of completely.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Effectively | Invalid | Total effective rate (%) | Serious adverse reaction example |
| Treatment group | 15 | 2 | 11 | 2 | 86.7% | 0 |
| Matched group | 15 | 1 | 7 | 7 | 53.3% | 0 |
Visible, the medicine that the present invention obtains can safe and effective treatment chronic pneumonia, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: 25 grams, lotus, Semen Lepidii (Semen Descurainiae) 9 grams on Herba Schizonepetae 5 grams, Concretio Silicea Bambusae 8 grams, Rhizoma Cynanchi Stauntonii 6 grams, Fructus Trichosanthis 10 grams, stone; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of chronic pneumonia.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: 25 grams, lotus, Semen Lepidii (Semen Descurainiae) 9 grams on Herba Schizonepetae 5 grams, Concretio Silicea Bambusae 8 grams, Rhizoma Cynanchi Stauntonii 6 grams, Fructus Trichosanthis 10 grams, stone; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of chronic pneumonia.Oral, daily once.
Specific embodiment 3
Take: 25 grams, lotus, Semen Lepidii (Semen Descurainiae) 9 grams on Herba Schizonepetae 5 grams, Concretio Silicea Bambusae 8 grams, Rhizoma Cynanchi Stauntonii 6 grams, Fructus Trichosanthis 10 grams, stone; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of chronic pneumonia.Oral, every bu is taken for twice sooner or later.
Claims (4)
1. be used for the treatment of a Chinese medicine for chronic pneumonia, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: 25 parts, lotus, Semen Lepidii (Semen Descurainiae) 9 parts on Herba Schizonepetae 5 parts, Concretio Silicea Bambusae 8 parts, Rhizoma Cynanchi Stauntonii 6 parts, Fructus Trichosanthis 10 parts, stone.
2. be used for the treatment of the Chinese medicine of chronic pneumonia as claimed in claim 1, it is characterized in that, its preparation method is: take: 25 parts, lotus, Semen Lepidii (Semen Descurainiae) 9 parts on Herba Schizonepetae 5 parts, Concretio Silicea Bambusae 8 parts, Rhizoma Cynanchi Stauntonii 6 parts, Fructus Trichosanthis 10 parts, stone; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of the Chinese medicine of chronic pneumonia as claimed in claim 1, it is characterized in that, its preparation method is: take: 25 parts, lotus, Semen Lepidii (Semen Descurainiae) 9 parts on Herba Schizonepetae 5 parts, Concretio Silicea Bambusae 8 parts, Rhizoma Cynanchi Stauntonii 6 parts, Fructus Trichosanthis 10 parts, stone; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of the Chinese medicine of chronic pneumonia as claimed in claim 1, it is characterized in that, its preparation method is: take: 25 parts, lotus, Semen Lepidii (Semen Descurainiae) 9 parts on Herba Schizonepetae 5 parts, Concretio Silicea Bambusae 8 parts, Rhizoma Cynanchi Stauntonii 6 parts, Fructus Trichosanthis 10 parts, stone; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410623268.0A CN104338040A (en) | 2014-11-09 | 2014-11-09 | Traditional Chinese medicine for treating chronic pneumonia |
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| CN201410623268.0A CN104338040A (en) | 2014-11-09 | 2014-11-09 | Traditional Chinese medicine for treating chronic pneumonia |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104888011A (en) * | 2015-06-17 | 2015-09-09 | 青岛海之星生物科技有限公司 | Traditional Chinese medicine capsule for treating pneumonia and preparation method of traditional Chinese medicine capsule |
| CN105708955A (en) * | 2016-04-13 | 2016-06-29 | 刘海强 | Medicine for treating chronic bronchitis |
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|---|---|---|---|---|
| CN101829287A (en) * | 2010-05-11 | 2010-09-15 | 史忠岚 | Traditional Chinese medicine composition for treating pediatric pneumonia |
| CN103636845A (en) * | 2013-12-07 | 2014-03-19 | 哈尔滨升益生物科技开发有限公司 | Formula and preparation method of honeysuckle pneumonia recovery tea |
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2014
- 2014-11-09 CN CN201410623268.0A patent/CN104338040A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101829287A (en) * | 2010-05-11 | 2010-09-15 | 史忠岚 | Traditional Chinese medicine composition for treating pediatric pneumonia |
| CN103636845A (en) * | 2013-12-07 | 2014-03-19 | 哈尔滨升益生物科技开发有限公司 | Formula and preparation method of honeysuckle pneumonia recovery tea |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104888011A (en) * | 2015-06-17 | 2015-09-09 | 青岛海之星生物科技有限公司 | Traditional Chinese medicine capsule for treating pneumonia and preparation method of traditional Chinese medicine capsule |
| CN105708955A (en) * | 2016-04-13 | 2016-06-29 | 刘海强 | Medicine for treating chronic bronchitis |
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Application publication date: 20150211 |