CN104337952A - Combined medicine for treating explosive deafness by combining traditional Chinese medicines and western medicine - Google Patents

Combined medicine for treating explosive deafness by combining traditional Chinese medicines and western medicine Download PDF

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CN104337952A
CN104337952A CN201310346083.5A CN201310346083A CN104337952A CN 104337952 A CN104337952 A CN 104337952A CN 201310346083 A CN201310346083 A CN 201310346083A CN 104337952 A CN104337952 A CN 104337952A
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李谊
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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Abstract

The invention relates to a combined medicine for treating explosive deafness by combining traditional Chinese medicines and a western medicine, and is used for effectively solving the problems of treatment medicines for explosive deafness. According to the technical scheme, the combined medicine comprises a traditional Chinese medicine component and a western medicine component, wherein the traditional Chinese medicine component comprises 10-30g of scutellaria baicalensis, 6-20g of lobed kudzuvine root, 5-10g of radix gentianae, 5-15g of gardenia jasminoides, 10-20g of unprepared rehmannia glutinosa, 10-20g of angelica sinensis, 10-15g of rhizoma alismatis, 10-15g of ligusticum wallichii, 3-30g of radix bupleuri, 10-30g of magnet, 10-30g of rhizoma acori graminei and 3-60g of liquorice; the western medicine component comprises 0.6g of ferrous sulfate. The combined medicine is effectively used for treating explosive deafness, is prepared from both traditional Chinese medicines and the western medicine, is good in treatment effect, free of toxic or side effect, convenient and simple to take, and safe and reliable, and can treat both symptoms and root causes.

Description

A kind of composition of medicine of therapy of combining Chinese and Western medicine explosion deafness
Technical field
The present invention relates to field of medicaments, particularly a kind of composition of medicine of therapy of combining Chinese and Western medicine explosion deafness.
Background technology
The internal ear acute acoustic trauma that explosion deafness mostly is blast, firearm is launched or other unexpected strong loud noises cause.Blast causer fiercely vibrates due to air, produces shock wave and very noisy, and noise intensity is often more than 140dBHL, and middle ear and internal ear all can go to pot simultaneously, cause spiral organ of Corti, tympanum and listen bone injury.Serious pinking or the atrophy along with Corti device, also can there is degeneration and atrophy in spiral ganglion cell, also can cause the damage of vestibular apparatus simultaneously, and the peeling-off phenomenon of its stone film also can occur.Other damage the damage that serious pinking can cause cranium brain and other positions, and occur the complication that stupor, shock etc. are serious.After vascular permeability increases pinking, in 2-6h, the blood vessel access of cochlea increases, and stop liquid and ooze out, severe patient can have floccule to ooze out.
Current explosion deafness does not have effective Drug therapy, often improve inner ear microcirculation clinically and be conducive to the medicine of cellular metabolism, as nicotinic acid, 654-2, vitamin, steroid, coenzyme A, adenosine triphosphate etc., but treat not good, though the existing Chinese medicine having treatment explosion deafness, but for various reasons, its curative effect unsatisfactory.Therefore, the medicine for treatment for explosion deafness is the difficult medical problem of being badly in need of capturing always.
Summary of the invention
For above-mentioned situation, for solving the defect of prior art, object of the present invention is just to provide a kind of composition of medicine of therapy of combining Chinese and Western medicine explosion deafness, effectively can solve the medicine for treatment problem to explosion deafness.
The technical scheme that the present invention solves is, medicine of the present invention comprises Chinese medicinal components and western medicine component, Chinese medicinal components is: Radix Scutellariae 10-30g, Radix Puerariae 6-20g, Radix Gentianae 5-10g, Fructus Gardeniae 5-15g, Radix Rehmanniae 10-20g, Radix Angelicae Sinensis 10-20g, Rhizoma Alismatis 10-15g, Rhizoma Chuanxiong 10-15g, Radix Bupleuri 3-30g, Magnetitum 10-30g, Rhizoma Acori Graminei 10-30g and Radix Glycyrrhizae 3-60g, and western medicine component is ferrous sulfate 0.6g.
Described Chinese medicinal components is the one of decoction, powder, powder, tablet, pill or the capsule that conventional method is made, and ferrous sulfate is tablet, every sheet 0.2g.
The present invention is effective to treat explosion deafness, is prepared, good effect, treating both the principal and secondary aspects of a disease, avirulence side effect by the combination of Chinese and Western medicine, taking convenience, simple, safe and reliable.
Detailed description of the invention
Below in conjunction with embodiment, the specific embodiment of the present invention is elaborated.
The present invention can be provided by following examples in concrete enforcement.
embodiment 1
The present invention is in concrete enforcement, this Chinese medicine comprises Chinese medicinal components and western medicine component, Chinese medicinal components is Radix Scutellariae 10g, Radix Puerariae 15g, Radix Gentianae 5g, Fructus Gardeniae 15g, Radix Rehmanniae 10g, Radix Angelicae Sinensis 10g, Rhizoma Alismatis 15g, Rhizoma Chuanxiong 15g, Radix Bupleuri 15g, Magnetitum 15g, Rhizoma Acori Graminei 15g and Radix Glycyrrhizae 10g, and western medicine component is ferrous sulfate 0.6g.
embodiment 2
The present invention is in concrete enforcement, this Chinese medicine comprises Chinese medicinal components and western medicine component, Chinese medicinal components is Radix Scutellariae 30g, Radix Puerariae 6g, Radix Gentianae 10g, Fructus Gardeniae 5g, Radix Rehmanniae 20g, Radix Angelicae Sinensis 20g, Rhizoma Alismatis 10g, Rhizoma Chuanxiong 10g, Radix Bupleuri 30g, Magnetitum 10g, Rhizoma Acori Graminei 10g and Radix Glycyrrhizae 60g, and western medicine component is ferrous sulfate 0.6g.
embodiment 3
The present invention is in concrete enforcement, this Chinese medicine comprises Chinese medicinal components and western medicine component, Chinese medicinal components is Radix Scutellariae 15g, Radix Puerariae 20g, Radix Gentianae 7g, Fructus Gardeniae 10g, Radix Rehmanniae 15g, Radix Angelicae Sinensis 15g, Rhizoma Alismatis 12g, Rhizoma Chuanxiong 12g, Radix Bupleuri 3g, Magnetitum 30g, Rhizoma Acori Graminei 30g and Radix Glycyrrhizae 3g, and western medicine component is ferrous sulfate 0.6g.
In above-mentioned medicine, wherein:
Radix Scutellariae: another name Radix Scutellariae, tsuchikane tea root.For labiate Radix Scutellariae, be used as medicine with root.Have heat clearing and damp drying, removing heat from blood is antiabortive, detoxicating functions.Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.The clinical practice of Radix Scutellariae is antibacterial not worse than Rhizoma Coptidis, and does not develop immunity to drugs.For hygropyrexia heating, uncomfortable in chest, feeling thirst but no desire to drink, and the disease such as damp-heat dysentery, jaundice.Hygropyrexia is generated heat; For the high hot excessive thirst of calentura, or cough due to lung-heat, or intenseness of heat forcing blood is excessive and pathopyretic ulcer etc.In addition, this product has again clearing heat and preventing abortion effect, can be used for frequent fetal movement, the normal and fit applications such as the Rhizoma Atractylodis Macrocephalae, Caulis Bambusae In Taenia.
Radix Puerariae: yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, relieving restlessness is temperature only.Cure the wound cold, warm headache stiffness of the nape, and dysphoria with smothery sensation is quenched one's thirst, and has loose bowels, dysentery, and skin eruption is not saturating, hypertension, and angina pectoris is deaf.
Radix Gentianae: liver heat removing gallbladder, dampness removing heat.For dampness-heat in the liver and gallbladder, dizziness and red eyes, Hiccough and deaf, hypochondriac pain bitter taste, dark coloured urine, damp-heat vaginal discharge.
Rhizoma Alismatis: control five kinds of strain and seven kinds of impairment, main head revolves, ear tinnitus of deficiency type, muscles and bones contracture, and logical small intestinal, only loses drop, hematuria.
Rhizoma Chuanxiong: be a kind of Chinese medicinal plant, be usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, the pungent temperature of Rhizoma Chuanxiong is fragrant dry, walks and does not keep, can go loose, and the up mountain peak that reaches is pushed up; Blood circulation promoting and blood stasis dispelling effect is extensive, the suitable various disease of stagnation of blood stasis; Wind-expelling pain-stopping, effectiveness is excellent, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia
Rhizoma Acori Graminei: enter heart channel, happy key, beneficial intelligence, tranquilizing mind, hearing-improing and eyesight improving, therefore can be used for forgetful, insomnia, tinnitus, deaf all diseases.Control heart kidney two void, Hiccough and deaf, giddy, cardiopalmus, normal and Semen Cuscutae, Fructus Ligustri Lucidi, Herba Ecliptae and the compatibility such as Radix Salviae Miltiorrhizae, Caulis Polygoni Multiflori, as ANSHEN BUXIN WAN.
Radix Glycyrrhizae: nature and flavor are put down, sweet in the mouth.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, the effects such as coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, cushion toxicity.The traditional Chinese medical science is thought all and is neither used Radix Glycyrrhizae because of wet caused vomiting and nausea, phlegm retention, fullness in the epigastrium and abdomen, edema etc.Modern pharmacological research also finds, Radix Glycyrrhizae is mainly containing glycyrrhizin, and glycyrrhizin has the effect of adrenocortical hormone sample, can promote water, sodium pool slips and arrange potassium increases, long-term extensive application Radix Glycyrrhizae, there will be edema, blood pressure increase, the reduction of blood potassium, the disease such as myasthenia of limbs.
Ferrous sulfate pharmaceutically makes anti-anemic drug, local convergence agent and hematinic.
The scientific combination of above-mentioned raw materials medicine, supports mutually, and Chinese and western drugs combines, can effectively prevent spiral ganglion cell from deforming and atrophy, and the peeling phenomenon of stone film, be effective to treat explosion deafness, and achieve satisfied effect through clinical trial, interrelated data is as follows:
One, the standard of case is selected
The internal ear acute acoustic trauma that explosion deafness mostly is blast, firearm is launched or other unexpected strong loud noises cause.Blast causer fiercely vibrates due to air, produces shock wave and very noisy, and noise intensity is often more than 140dBHL, and middle ear and internal ear all can go to pot simultaneously, cause spiral organ of Corti, tympanum and listen bone injury.Serious pinking or the atrophy along with Corti device, also can there is degeneration and atrophy in spiral ganglion cell, also can cause the damage of vestibular apparatus simultaneously, and the peeling-off phenomenon of its stone film also can occur.Other damage the damage that serious pinking can cause cranium brain and other positions, and occur the complication that stupor, shock etc. are serious.After vascular permeability increases pinking, in 2-6h, the blood vessel access of cochlea increases, and body fluid oozes out, and severe patient can have floccule to ooze out.
All persons that has above-mentioned symptom, all as the standard selecting case, and give composition of medicine of the present invention and treat.
Two, diagnostic criteria
By having symptom described in above-mentioned, and show as clinically:
1, hemorrhage: position, internal ear many places can be caused after pinking hemorrhage, and even the position such as bottom of internal acoustic meatus, acoustic nerve is hemorrhage.
2, auditory dysesthesia :-as can there is auditory dysesthesia after pinking, the total hearing loss in a short time had, recovers subsequently gradually.Occurring in the normal of injury of middle ear is conductive deafness, inside story and injury of acoustic nerve be phonosensitive nerve deafness, both persons of having concurrently cause mixed deafness, and serious pinking can cause permanent deaf tinnitus.
3, dizzy: mostly to be rotatory vertigo, general symptom is comparatively light, and the persistent period is not long, and the vestibule concussion that severe patient causes after seeing cochlea damage, shows as the symptom such as Nausea and vomiting, dysequilibrium.
4, middle ear change: middle ear are main portions of wound after pinking, the lighter causes tympanum congested or hemorrhage, and severe one causes the perforation of ear drum to break, and little FFI perforation can be healed hindering in the Later Zhou Dynasty, one of the Five Dynasties, if 6 weeks perforated edges are still formed without new vessels after wound, then the probability of normal healing is little.Normal bleeding, hematocele, auditory ossicles come off or fracture in tympanum, and the visible tympanum of severe one moves that film is torn, rupture of round window membrane etc.
, as accompanied head trauma to produce concuss of labyrinth simultaneously, there is Nausea Under Vestibular Stimulus, as nystagmus etc. in 5, vestibule symptom: injuredly at once can accompany temporarily dizzy.
6, have a headache: see strong pinking, multidigit is in forehead, occipitalia and forehead, and a few patients can be full headache, headache side is relevant with the direction of pinking, and serious injury of middle ear also can cause side to have a headache.
7, Corti device structure element disorderly: pinking can cause device part, and even total is disorderly, and outer hair cell is got involved at first, and be secondly outer cell, severe patient inner hair cells also will be got involved, the qualitative change of even whole Corti device and disappearance.
8, otalgia: be common in the perforation of ear drum, tympanum is eaten film and the injury of middle ear such as to be torn, and can disappear in the general a few days.
Diagnosable is explosion deafness.
Three, therapeutic scheme
To making a definite diagnosis the person that suffers from explosion deafness, give Drug therapy of the present invention, therapeutic scheme is, the prescription amount provided by the present invention adds water to submerge, steep to 30-60 minute, after being fried boiling with high heat, then 30-40 minute at a simmer, filter, obtain first time decocting liquid, medicinal residues add water to submerge again, after being fried boiling with high heat, 20-30 minute at a simmer again, filter, obtain second time decocting liquid, merge twice decocting liquid, be divided into two parts, sooner or later respectively take portion, while taking Chinese medicine, coordinate and take each 0.3g of ferrous sulfate, recipe quantity potion on the one pressed by Chinese medicine, serve on 1-2 month.The 6-8 that decoction of the present invention adds Chinese medicinal components weight by recipe quantity soak by water doubly 2 times, collecting decoction, is condensed into the oral liquid of relative density 1.1-1.4, each oral 10-20ml, 3 times on the one, serve on 1-2 month.
Four, efficacy assessment standard
Effective (clinical cure): auditory rehabilitation is normal, in ear bleeding disappears, and headache, otalgia symptom alleviate or disappear completely, and tympanum is obviously not congested.
Effective: symptom makes moderate progress improvement, needs continual cure.
Invalid: symptom, without improvement, even has the trend of deterioration.
Five, statistical procedures
Patient diagnosed is coordinated with Western medicine ferrous sulfate by Chinese medicine decoction of the present invention, through different to 189 routine damaged degree, after the patient that clinical manifestation symptom is not quite similar is undertaken treatment 1-2 month by the Therapeutic Method that the present invention provides, wherein 163 routine patient's audition recover normal gradually, in ear bleeding disappears, headache, otalgia symptom alleviate or disappear completely, tympanum is obviously not congested, 21 routine patients symptomatic alleviate effectively, 5 routine patients symptomatic are without any improvement, total effective rate 97.4%, and during medication, find no any untoward reaction.
Other dosage form, through on probation, all achieves identical or akin result, and the core of the present invention's protection is Chinese medicine composition (formula); and make other dosage form according to a conventional method; being the technological means that those skilled in the art commonly use, is also known basic general knowledge, therefore describes in detail no longer one by one or tired to state.
Six, conclusion
Can clearly be found out by above-mentioned situation, composition of medicine of the present invention adopts combination of Chinese and Western medicine preparation, good effect, treating both the principal and secondary aspects of a disease, avirulence side effect, taking convenience, simple, stable curative effect, safe and reliable, effective percentage is up to more than 97%, both having avoided the normal flora imbalance of taking antibiotic and may cause, to have given full play to the unique effects for the treatment of by Chinese herbs explosion deafness, is that in the medication for the treatment of explosion deafness innovates greatly.

Claims (5)

1. the composition of medicine of a therapy of combining Chinese and Western medicine explosion deafness, comprise Chinese medicinal components and western medicine component, Chinese medicinal components is: Radix Scutellariae 10-30g, Radix Puerariae 6-20g, Radix Gentianae 5-10g, Fructus Gardeniae 5-15g, Radix Rehmanniae 10-20g, Radix Angelicae Sinensis 10-20g, Rhizoma Alismatis 10-15g, Rhizoma Chuanxiong 10-15g, Radix Bupleuri 3-30g, Magnetitum 10-30g, Rhizoma Acori Graminei 10-30g and Radix Glycyrrhizae 3-60g, and western medicine component is ferrous sulfate 0.6g.
2. the composition of medicine of therapy of combining Chinese and Western medicine explosion deafness according to claim 1, it is characterized in that, comprise Chinese medicinal components and western medicine component, Chinese medicinal components is Radix Scutellariae 10g, Radix Puerariae 15g, Radix Gentianae 5g, Fructus Gardeniae 15g, Radix Rehmanniae 10g, Radix Angelicae Sinensis 10g, Rhizoma Alismatis 15g, Rhizoma Chuanxiong 15g, Radix Bupleuri 15g, Magnetitum 15g, Rhizoma Acori Graminei 15g and Radix Glycyrrhizae 10g, and western medicine component is ferrous sulfate 0.6g.
3. the composition of medicine of therapy of combining Chinese and Western medicine explosion deafness according to claim 1, it is characterized in that, comprise Chinese medicinal components and western medicine component, Chinese medicinal components is Radix Scutellariae 30g, Radix Puerariae 6g, Radix Gentianae 10g, Fructus Gardeniae 5g, Radix Rehmanniae 20g, Radix Angelicae Sinensis 20g, Rhizoma Alismatis 10g, Rhizoma Chuanxiong 10g, Radix Bupleuri 30g, Magnetitum 10g, Rhizoma Acori Graminei 10g and Radix Glycyrrhizae 60g, and western medicine component is ferrous sulfate 0.6g.
4. the composition of medicine of therapy of combining Chinese and Western medicine explosion deafness according to claim 1, it is characterized in that, comprise Chinese medicinal components and western medicine component, Chinese medicinal components is Radix Scutellariae 15g, Radix Puerariae 20g, Radix Gentianae 7g, Fructus Gardeniae 10g, Radix Rehmanniae 15g, Radix Angelicae Sinensis 15g, Rhizoma Alismatis 12g, Rhizoma Chuanxiong 12g, Radix Bupleuri 3g, Magnetitum 30g, Rhizoma Acori Graminei 30g and Radix Glycyrrhizae 3g, and western medicine component is ferrous sulfate 0.6g.
5. the composition of medicine of the therapy of combining Chinese and Western medicine explosion deafness according to claim 1 or any one of 2-4, is characterized in that, described Chinese medicinal components makes the one of decoction, powder, powder, tablet, pill or capsule according to a conventional method.
CN201310346083.5A 2013-08-10 2013-08-10 Combined medicine for treating explosive deafness by combining traditional Chinese medicines and western medicine Pending CN104337952A (en)

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* Cited by examiner, † Cited by third party
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