CN103405660B - Compound medicine for treating headache - Google Patents

Abstract

The invention provides compound medicine for treating headache. The compound medicine is prepared through the steps as follows: uniformly mixing the crude drugs in parts by weight: 10-30 parts of ligusticum wallichii, 10-30 parts of schizonepeta, 10-30 parts of Chinese parsnip root, 5-20 parts of notopterygium root, 3-20 parts of radix angelicae, 3-15 parts of asarum, 10-20 parts of radices ligustici sinensis, 3-20 parts of gastrodia elata, 10-20 parts of uncaria rhynchophylla, 10-20 parts of rhizoma anemarrhenae and 10-30 parts of radix scutellariae, and extracting TCM active components; decocting the mixture with water for 3 times taking 0.5-1 hour every time,combining the three-time decoction, filtering, and concentrating to form the thick paste with the temperature of 60 DEG C and the relative density of 1.25-1.3, drying the thick paste at the temperature of 50-60 DEG C, and crushing the thick paste into powder with 100 meshes; adding the crude drugs of 0.25-5 parts of diazepam and 0.05-1 part of vitamin B1 by weight to the extracted TCM active components, uniformly mixing and putting the mixture into a capsule, and performing sterilization to obtain the capsule product. The compound medicine provided by the invention has the functions of expelling wind chill and stopping pain, and is short in course of treatment of acute and chronic headache, and effective in treatment. Through clinical observation of curative effects of 50 patients, 45 patients are cured, the illness conditions of 4 patients are improved, one patient is not cured due to ineffectiveness of the compound medicine, the effective rate is 98%, and the cure rate is 90%. During medication, no adverse reaction exists.

Description

A kind of compound medicine for the treatment of headache

Technical field

The present invention relates to a kind of medicine for the treatment of headache, particularly relate to a kind of compound medicine for the treatment of headache of compatibility Chinese medicine in Western medicine.

Background technology

Headache degree has gently to be had heavily, and it is short that pain time has length to have.Pain form is varied, common distending pain, vexed pain, tears sample pain, electric shock sample pain, prickling-like pain, and part is with vascular pulsation sense and the sense of head lock ring, and the symptom such as Nausea and vomiting, dizziness.Secondary headache also can with other system disease symptoms or sign, and if infectious disease is often with heating, vascular lesion often accompanies the neurologic impairment such as hemiplegia, aphasia symptom etc.Headache produces different harm according to degree, is in a bad way and patient can be made to lose live and work ability.Traditional therapy is single medication, or single antiinflammatory, pain relieving, and temporary transient relief of symptoms but can not prolongedly be cured.

Summary of the invention

The object of this invention is to provide the compound medicine that a kind of curative effect is fast, the treatment of short treating period is had a headache.

Medicine of the present invention is prepared by the crude drug of following ratio of weight and number:

Rhizoma Chuanxiong 10-30 Herba Schizonepetae 10-30

Radix Saposhnikoviae 10-30 Rhizoma Et Radix Notopterygii 5-20

Radix Angelicae Dahuricae 3-20 Herba Asari 3-15

Rhizoma Ligustici 10-20 Rhizoma Gastrodiae 3-20

Ramulus Uncariae Cum Uncis 10-20 Radix Scutellariae 10-30

Rhizoma Anemarrhenae 10-20 stabilizes 0.25-5

Vitamin B1 0.05-1.

The preferred weight number of described each crude drug is:

Rhizoma Chuanxiong 20 Herba Schizonepetae 20

Radix Saposhnikoviae 20 Rhizoma Et Radix Notopterygii 10

The Radix Angelicae Dahuricae 15 Herba Asari 8

Rhizoma Ligustici 15 Rhizoma Gastrodiae 12

Ramulus Uncariae Cum Uncis 12 Radix Scutellariae 20

The Rhizoma Anemarrhenae 12 stable 2

Vitamin B1 0.5.

By above-mentioned various Chinese medicine according to after described ratio of weight and number mix homogeneously, extract the active component of Chinese medicine: decoct with water 3 times, each 0.5 ~ 1 hour, merge 3 decocting liquids, filter, being condensed into 60 DEG C of relative densities is the thick paste of 1.25 ~ 1.3, after 50 ~ 60 DEG C of dryings, is crushed to 100 object medicated powder; During stable, the vitamin B1 mix homogeneously that add described parts by weight in the active Chinese drug component component extracted incapsulate, sterilization obtains capsule product.This product every is heavy 1.5 grams.

In prescription of the present invention, Rhizoma Chuanxiong acrid in the mouth, warm in nature, pungent energy falls apart, and Wen Nengtong, has blood-activating and qi-promoting, the effect of wind-expelling pain-stopping; Herba Schizonepetae acrid in the mouth, slightly warm in nature, energy relieving the exterior syndrome by diaphoresis, dispersing wind and cold, refresh oneself; Radix Saposhnikoviae acrid-sweet flavor, slightly warm in nature, has the effect that Pulvis Diaphoreticus wind and cold dehumidifies; Rhizoma Et Radix Notopterygii acrid in the mouth is bitter, warm in nature, has relieving the exterior syndrome by diaphoresis, dispersing wind and cold, the effect of dehumidifying; Radix Angelicae Dahuricae acrid in the mouth, warm in nature, can dispersing wind and cold be delivered, the kind neck effect controlled wind and cold and cause; Herba Asari acrid in the mouth, warm in nature, the wind and cold of shaoyang channel of faling apart, and can pain relieving; Rhizoma Ligustici acrid in the mouth, warm in nature, have and control head mountain peak and push up the effect of having a pain; Rhizoma Gastrodiae sweet in the mouth, property is put down, and has to put down to put out liver-wind, removes the effect of spasm; Ramulus Uncariae Cum Uncis sweet in the mouth, cold nature, has that heat clearing away is peaceful puts out liver wind action; Radix Scutellariae bitter in the mouth, cold in nature, there is the effect of heat clearing and damp drying; Rhizoma Anemarrhenae bitter in the mouth, cold in nature, there is the effect that heat clearing away is nourshing Yin and drynsessmoistening prescription; Stable this product has stable, calm, hypnosis, anxiety, convulsion, epilepsy and maincenter myorelaxant effects; Vitamin B1 is mainly used in polyneuritis, peripheral neuritis, central nervous system injury, malnutrition etc.

For investigating the clinical efficacy of Drug therapy of the present invention headache further, 50 routine headaches are selected to carry out clinical observation on the therapeutic effect.

Clinical data:

Select outpatient 50 example, wherein man 30 example, female 20 example, the course of disease 3 months ~ 1 year, 0 ~ 50 years old age.

Tcm diagnosis standard

The clinical syndrome diagnostic criterion of People's Republic of China's traditional Chinese medicine industry standard " disease of tcm Standardization of diagnosis and curative effect " according to nineteen ninety-five State Administration of Traditional Chinese Medicine promulgates: headache shows as the volume of side (being individually both sides), temporo, orbital part have an intense pain, headache can be twinge, distending pain, with the feature of the corresponding pattern of syndrome such as uncomfortable in chest, fever with chills, breast wrist painful abdominal mass be vexed, tongue arteries and veins is also different with symptom.

Therapeutic Method: oral medicine of the present invention, oral one time 5, three times on the one, one after each meal.Within 10 days, be a course for the treatment of, take 2 courses for the treatment of.

TCM syndrome criterion of therapeutical effect

" new Chinese medicine guideline of clinical investigations " with reference to Ministry of Health of the People's Republic of China's nineteen ninety-five is issued:

Clinical recovery: headache and simultaneous phenomenon disappear more than 6 months without recurrence;

Effective: pain intensity alleviates 2 grades, and simultaneous phenomenon alleviates, or attack times or durante dolors reduce more than 2/3;

Effective: pain intensity alleviates 1 grade, or outbreak interval extends, or headache decreased duration is less than 2/3;

Invalid: pain intensity alleviates less than 1 grade, or durante dolors shortens less than 1/3, or pain increases the weight of, duration extension.

Therapeutic outcome:

2 courses for the treatment of of 50 routine patient's oral administration Drug therapy of the present invention, cure 45 examples, 4 examples that take a turn for the better, invalid 1 example, effective percentage 98%, cure rate 90%.Period in a medicine, has no adverse reaction.

Detailed description of the invention

Embodiment 1

Take removing impurity, after the Rhizoma Chuanxiong 10g cleaned up, Herba Schizonepetae 10g, Radix Saposhnikoviae 10g, Rhizoma Et Radix Notopterygii 5g, Radix Angelicae Dahuricae 3g, Herba Asari 3g, Rhizoma Ligustici 10g, Rhizoma Gastrodiae 3g, Ramulus Uncariae Cum Uncis 10g, Rhizoma Anemarrhenae 10g, Radix Scutellariae 10g mix homogeneously, extract the active component of Chinese medicine: decoct with water 3 times, each 0.5 ~ 1 hour, merge 3 decocting liquids, filter, being condensed into 60 DEG C of relative densities is the thick paste of 1.25 ~ 1.3, after 50 ~ 60 DEG C of dryings, be crushed to 100 object medicated powder; In the active Chinese drug component component extracted, add stable 0.25g, during vitamin B1 0.05g mix homogeneously incapsulates, sterilization obtains capsule product.This product every is heavy 1.5 grams.

Using method: oral one time 5, three times on the one, one after each meal.

Embodiment 2

Take removing impurity, after the Rhizoma Chuanxiong 20g cleaned up, Herba Schizonepetae 20g, Radix Saposhnikoviae 20g, Rhizoma Et Radix Notopterygii 10g, Radix Angelicae Dahuricae 15g, Herba Asari 8g, Rhizoma Ligustici 15g, Rhizoma Gastrodiae 12g, Ramulus Uncariae Cum Uncis 12g, Rhizoma Anemarrhenae 12g, Radix Scutellariae 20g mix homogeneously, extract the active component of Chinese medicine: decoct with water 3 times, each 0.5 ~ 1 hour, merge 3 decocting liquids, filter, being condensed into 60 DEG C of relative densities is the thick paste of 1.25 ~ 1.3, after 50 ~ 60 DEG C of dryings, be crushed to 100 object medicated powder; In the active Chinese drug component component extracted, add stable 2g, during vitamin B1 0.5g mix homogeneously incapsulates, sterilization obtains capsule product.This product every is heavy 1.5 grams.

Using method: oral one time 5, three times on the one, one after each meal.

Embodiment 3

Take removing impurity, after the Rhizoma Chuanxiong 30g cleaned up, Herba Schizonepetae 30g, Radix Saposhnikoviae 30g, Rhizoma Et Radix Notopterygii 20g, Radix Angelicae Dahuricae 20g, Herba Asari 15g, Rhizoma Ligustici 20g, Rhizoma Gastrodiae 20g, Ramulus Uncariae Cum Uncis 20g, Rhizoma Anemarrhenae 20g, Radix Scutellariae 30g mix homogeneously, extract the active component of Chinese medicine: decoct with water 3 times, each 0.5 ~ 1 hour, merge 3 decocting liquids, filter, being condensed into 60 DEG C of relative densities is the thick paste of 1.25 ~ 1.3, after 50 ~ 60 DEG C of dryings, be crushed to 100 object medicated powder; In the active Chinese drug component component extracted, add stable 5g, during vitamin B1 1g mix homogeneously incapsulates, sterilization obtains capsule product.This product every is heavy 1.5 grams.

Using method: oral one time 5, three times on the one, one after each meal.

Claims (3)

1. treating a compound medicine for headache, is prepared by the crude drug of following ratio of weight and number:

Rhizoma Chuanxiong 10-30 Herba Schizonepetae 10-30

Radix Saposhnikoviae 10-30 Rhizoma Et Radix Notopterygii 5-20

Radix Angelicae Dahuricae 3-20 Herba Asari 3-15

Rhizoma Ligustici 10-20 Rhizoma Gastrodiae 3-20

Ramulus Uncariae Cum Uncis 10-20 Radix Scutellariae 10-30

Rhizoma Anemarrhenae 10-20 stabilizes 0.25-5

Vitamin B1 0.05-1.

2. the compound medicine for the treatment of headache according to claim 1, wherein the parts by weight of each crude drug are:

Rhizoma Chuanxiong 20 Herba Schizonepetae 20

Radix Saposhnikoviae 20 Rhizoma Et Radix Notopterygii 10

The Radix Angelicae Dahuricae 15 Herba Asari 8

Rhizoma Ligustici 15 Rhizoma Gastrodiae 12

Ramulus Uncariae Cum Uncis 12 Radix Scutellariae 20

The Rhizoma Anemarrhenae 12 stable 2

Vitamin B1 0.5.

3. the compound medicine of headache according to claim 1 and 2, is characterized in that described medicine to make capsule.