CN104323875A - Bone grafting device for repairing large segmental bone defects - Google Patents
Bone grafting device for repairing large segmental bone defects Download PDFInfo
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- CN104323875A CN104323875A CN201410539753.XA CN201410539753A CN104323875A CN 104323875 A CN104323875 A CN 104323875A CN 201410539753 A CN201410539753 A CN 201410539753A CN 104323875 A CN104323875 A CN 104323875A
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- bone
- grafting device
- bone grafting
- sleeve pipe
- obturator
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Abstract
The invention relates to a bone grafting device for repairing large segmental bone defects. The bone grafting device comprises a bone defect area formed between two bone stumps, wherein a mesh cannula with two ends connected with the two bone stumps respectively is arranged on the bone defect area; an osteogenesis filler is arranged in the cannula; a vacuum aspiration tube is arranged; one end of the vacuum aspiration tube is connected with a vacuum aspiration machine; the other end of the vacuum aspiration tube is inserted into the filler so as to provide vacuum environment for the filler osteogenesis. According to the bone grafting device for repairing the large segmental bone defects, bones are grafted in the cannula, so that the bone formation has directionality, the effective osteogenesis quantity is increased, soft tissues in the bone defect area are prevented from entering into bone grafting blocks, and bone growth factors can enter smoothly; the mechanical stretching of cells is caused in the defect area through vacuum, the growth of the cells and granulation tissues is promoted, and the expression of the cell factors such as TGF (Transforming Growth Factor) and VEGF (Vascular Endothelial Growth Factor) is promoted, so that the aim of quick union is achieved.
Description
Technical field
The present invention relates to bone grafting device, is the bone grafting device repairing large segmental bone defect specifically.
Background technology
At present, have several to the reparation of large segmental bone defect, the first is autologous bone transplanting, and it has best bone conduction, self-bone grafting and osteogenesis effect, but due to limited for bone amount, and bone strength is not good enough, is not suitable for the reconstruction of heavy burden district Cranial defect; The second is the autologous bone transplanting of anastomosis of blood vessel, and its long bone of limbs large section of defect being difficult to repair for traditional bone grafting has good effect, but limited for bone amount, and to the damage caused for bone district again; The third be homogeneous allogenic bone and artificial prosthesis for Cranial defect, according to the size of defective region and shape Selection utilization, wide material sources, but can have rejection, healing is slow; 4th kind is band blood vessel homogeneous allogenic bone transplantation, and the natural structure of itself, form, self-bone grafting ability are strong, but at the experimental stage; 5th kind is bone carrying and Limb lengthening, and its curative effect certainly, also have irreplaceable advantage to a certain extent, but healing time is long; 6th kind is, tissue engineered bone and artificial bone substitute materials, it is drawn materials extensively, but at the experimental stage.
Summary of the invention
For above-mentioned technical problem, the invention provides a kind of bone inductive effect and the osteoconductive potential that improve allograph bone, to improve the bone grafting device of knitting speed and active strength.
The present invention solves the problems of the technologies described above adopted technical scheme: the bone grafting device repairing large segmental bone defect, comprise the Cranial defect district be formed between two bone stumps, be provided with the netted sleeve pipe that two ends are connected with two bone stumps respectively in Cranial defect district, being provided with in this sleeve pipe can the obturator of skeletonization; Be provided with negative-pressure suction pipe, this negative-pressure suction pipe one end is connected with vacuum suction machine, and other end radial direction is inserted in described obturator as this obturator skeletonization provides subnormal ambient.
As preferably, described sleeve pipe adopts PGA material to make.
As preferably, described sleeve pipe is grenadine jacket casing pipe.
As preferably, described sleeve pipe tilts to insert in described obturator.
As preferably, the paragraph that described sleeve pipe is positioned at obturator comprises tilting section and the horizontal segment with this tilting section rounding off.
As preferably, described horizontal segment is parallel with the axis of sleeve pipe.
As preferably, the tube wall of described horizontal segment and tilting section all opens several through hole.
As preferably, the distal end faces of described horizontal segment is closed, and this Closed End has opened several air-vent.
As preferably, described obturator is homogeneous allogenic bone.
As can be known from the above technical solutions, the present invention, at netted sleeve pipe interplantation bone, makes bone formation have directivity, increases and effectively becomes bone amount, avoid the soft tissue in Cranial defect region to enter in plant bone mass, and do not affect entering of skeletal growth factor; And in defective region, cause the mechanicalness of cell to uphold by negative pressure, promote cell and granulation tissue growth, the cytokine-expressings such as TGF, VEGF are promoted, thus reaches the object of quickly-healing.
Accompanying drawing explanation
Fig. 1 is structure chart of the present invention;
Fig. 2 is the profile of negative tube in the present invention.
Detailed description of the invention
The present invention is introduced in detail below in conjunction with accompanying drawing:
Bone grafting device of the present invention comprises the Cranial defect district 2 be formed between two bone stumps 1, is provided with the netted sleeve pipe 3 that two ends are connected with two bone stumps respectively in Cranial defect district, and being provided with in this sleeve pipe can the obturator 4 of skeletonization, and obturator preferably adopts homogeneous allogenic bone; The present invention is provided with negative-pressure suction pipe 5, and this negative-pressure suction pipe one end is connected with vacuum suction machine 6, also directly can connect the vacuum suction connector of hospital, and negative-pressure suction pipe other end radial direction is inserted in described obturator as obturator skeletonization provides subnormal ambient.In implementation process, the mesh of described netted sleeve pipe need reach following requirement: the soft tissue in Cranial defect region must be stoped to enter in obturator, skeletal growth factor should be made to enter obturator; In order to meet above-mentioned requirements, the present invention preferably uses grenadine jacket casing pipe, and adopts PGA material to make, and this material can directly absorb in osteogenetic process.
In operation process, first after grenadine jacket casing pipe being placed in defective region, then in sleeve pipe, homogeneous allogenic bone is filled, again negative-pressure suction pipe is radially inserted the obturator implanted from sleeve pipe, last tight suture fascia and skin, make to form certain negative pressure in negative-pressure suction pipe, subnormal ambient can make week non-tissue blood vessel fit tightly; Homogeneous allogenic bone in PGA sleeve pipe enables planted allosome skeletonization in 3 D stereo, can increase and effectively become bone amount, reduces lopsided skeletonization, and the subnormal ambient in sleeve pipe also can provide abundant blood to transport.
In the present invention, the paragraph that described sleeve pipe 5 is positioned at obturator comprises tilting section 51 and the horizontal segment 52 with this tilting section rounding off, the insertion of sleeve pipe can be facilitated like this and extract, described horizontal segment is preferably parallel with the axis of sleeve pipe, make the negative pressure in sleeve pipe comparatively even like this, be conducive to even skeletonization.In implementation process, finally on the tube wall of described horizontal segment and tilting section, all opened several through hole 53, this through hole should avoid obturator by absorption tube, causes cannula occlusion; As preferably, the distal end faces of described horizontal segment is closed, and this Closed End has been opened several air-vent 54; In implementation process, should on the basis ensureing the serviceability that sleeve pipe is complete, arrange air-vent and through hole as much as possible, even if the hole of a part is blocked like this, another part hole still can provide the subnormal ambient of skeletonization.
The present invention is implanted into homogeneous allogenic bone at PGA sleeve pipe, bootable Cranial defect bone district skeletonization, increases and effectively becomes bone amount; In PGA sleeve pipe, provide continuous negative pressure simultaneously, Cranial defect bone district skeletonization can be promoted, shorten healing time; In addition, the subnormal ambient of PGA sleeve pipe can form callus, i.e. skeletonization around the line of force between the distance end cortical bone in long diaphysis Cranial defect district.
Above-mentioned embodiment is used for illustrative purposes only, and be not limitation of the present invention, the those of ordinary skill of relevant technical field, without departing from the spirit and scope of the present invention, can also make various change and modification, therefore all equivalent technical schemes also should belong to category of the present invention.
Claims (9)
1. repair the bone grafting device of large segmental bone defect, comprise the Cranial defect district be formed between two bone stumps, it is characterized in that: be provided with the netted sleeve pipe that two ends are connected with two bone stumps respectively in Cranial defect district, being provided with in this sleeve pipe can the obturator of skeletonization; Be provided with negative-pressure suction pipe, this negative-pressure suction pipe one end is connected with vacuum suction machine, and other end radial direction is inserted in described obturator as this obturator skeletonization provides subnormal ambient.
2. bone grafting device according to claim 1, is characterized in that: described sleeve pipe adopts PGA material to make.
3. bone grafting device according to claim 2, is characterized in that: described sleeve pipe is grenadine jacket casing pipe.
4. the bone grafting device according to claim 1 or 2 or 3, is characterized in that: described sleeve pipe tilts to insert in described obturator.
5. bone grafting device according to claim 4, is characterized in that: the paragraph that described sleeve pipe is positioned at obturator comprises tilting section and the horizontal segment with this tilting section rounding off.
6. bone grafting device according to claim 5, is characterized in that: described horizontal segment is parallel with the axis of sleeve pipe.
7. bone grafting device according to claim 5, is characterized in that: the tube wall of described horizontal segment and tilting section has all opened several through hole.
8. bone grafting device according to claim 5, is characterized in that: the distal end faces of described horizontal segment is closed, and this Closed End has opened several air-vent.
9. bone grafting device according to claim 4, is characterized in that: described obturator is homogeneous allogenic bone.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410539753.XA CN104323875B (en) | 2014-10-14 | 2014-10-14 | Bone grafting device for repairing large segmental bone defects |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410539753.XA CN104323875B (en) | 2014-10-14 | 2014-10-14 | Bone grafting device for repairing large segmental bone defects |
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| CN104323875A true CN104323875A (en) | 2015-02-04 |
| CN104323875B CN104323875B (en) | 2017-01-18 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410539753.XA Active CN104323875B (en) | 2014-10-14 | 2014-10-14 | Bone grafting device for repairing large segmental bone defects |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107028687A (en) * | 2017-06-05 | 2017-08-11 | 南方医科大学 | A kind of clavicle near-end anatomical form prosthese and forming method |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107028687A (en) * | 2017-06-05 | 2017-08-11 | 南方医科大学 | A kind of clavicle near-end anatomical form prosthese and forming method |
| CN107028687B (en) * | 2017-06-05 | 2019-05-31 | 南方医科大学 | A kind of clavicle proximal end anatomical form prosthese and forming method |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104323875B (en) | 2017-01-18 |
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Effective date of registration: 20180319 Address after: 410000 No. 138, Tongzi Road, Yuelu District, Hunan, Changsha Patentee after: The Third Hospital of Central South University Address before: 410000 No. 138, Tongzi Road, Yuelu District, Hunan, Changsha Co-patentee before: Zhou Jiahui Patentee before: Liu Zhendong |