CN104323875B - Bone grafting device for repairing large segmental bone defects - Google Patents

Bone grafting device for repairing large segmental bone defects Download PDF

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Publication number
CN104323875B
CN104323875B CN201410539753.XA CN201410539753A CN104323875B CN 104323875 B CN104323875 B CN 104323875B CN 201410539753 A CN201410539753 A CN 201410539753A CN 104323875 B CN104323875 B CN 104323875B
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China
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bone
grafting device
bone grafting
obturator
sleeve pipe
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CN201410539753.XA
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CN104323875A (en
Inventor
刘振东
周嘉辉
陈腾飞
吴松
张克祥
王魁向
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The Third Hospital of Central South University
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刘振东
周嘉辉
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Abstract

The invention relates to a bone grafting device for repairing large segmental bone defects. The bone grafting device comprises a bone defect area formed between two bone stumps, wherein a mesh cannula with two ends connected with the two bone stumps respectively is arranged on the bone defect area; an osteogenesis filler is arranged in the cannula; a vacuum aspiration tube is arranged; one end of the vacuum aspiration tube is connected with a vacuum aspiration machine; the other end of the vacuum aspiration tube is inserted into the filler so as to provide vacuum environment for the filler osteogenesis. According to the bone grafting device for repairing the large segmental bone defects, bones are grafted in the cannula, so that the bone formation has directionality, the effective osteogenesis quantity is increased, soft tissues in the bone defect area are prevented from entering into bone grafting blocks, and bone growth factors can enter smoothly; the mechanical stretching of cells is caused in the defect area through vacuum, the growth of the cells and granulation tissues is promoted, and the expression of the cell factors such as TGF (Transforming Growth Factor) and VEGF (Vascular Endothelial Growth Factor) is promoted, so that the aim of quick union is achieved.

Description

Repair the bone grafting device of large segmental bone defect
Technical field
The present invention relates to bone grafting device, specifically repair the bone grafting device of large segmental bone defect.
Background technology
At present, the reparation of large segmental bone defect is had several, the first is autologous bone transplanting, its have optimal osteoacusis, Self-bone grafting and ostosis effect, but due to limited for bone amount, and bone strength is not good enough, is not suitable for the reconstruction of heavy burden area Cranial defect;The Two kinds be anastomosis of blood vessel autologous bone transplanting, big section of defect of long bone of limbs that it is difficult to repair for traditional bone grafting have preferably Effect, but limited for bone amount, and to the damage causing again for bone area;The third is homogeneous allogenic bone and artificial prosthesis are used for bone Defect, according to the size of defective region and shape Selection utilization, wide material sources, but can have rejection, and healing is slow;4th kind is Band blood vessel homogeneous allogenic bone transplantation, the natural structure of itself, form, self-bone grafting ability are strong, but at the experimental stage;5th kind It is bone carrying and Limb lengthening, its curative effect certainly, also has irreplaceable advantage to a certain extent, but healing time is long;The Six kinds are, tissue engineered bone and artificial bone substitute materials, and it is drawn materials extensively, but at the experimental stage.
Content of the invention
For above-mentioned technical problem, the present invention provides a kind of bone inductive effect improving allograph bone and osteoconductive potential, To improve the bone grafting device of knitting speed and active strength.
The technical scheme that present invention solution above-mentioned technical problem is adopted is: repairs the bone grafting device of large segmental bone defect, bag Include the Cranial defect area being formed between two bone stumps, Cranial defect area is provided with the mesh jacket that two ends are connected with two bone stumps respectively Pipe, be provided with this sleeve pipe can skeletonization obturator;It is provided with negative-pressure suction pipe, this negative-pressure suction pipe one end is with vacuum suction machine even Connect, the other end is inserted radially in described obturator and provides subnormal ambient for this obturator skeletonization.
Preferably, described sleeve pipe is made using pga material.
Preferably, described sleeve pipe is grenadine jacket casing pipe.
Preferably, described negative-pressure suction pipe tilts to insert in described obturator.
Preferably, described negative-pressure suction pipe be located at the internal paragraph of filling include tilting section and with this tilting section round and smooth mistake The horizontal segment crossing.
Preferably, described horizontal segment and sleeve pipe is axially in parallel.
Preferably, all having issued several through holes on described horizontal segment and the tube wall of tilting section.
Preferably, the distal end faces closing of described horizontal segment, several air-vents are issued on this Closed End.
Preferably, described obturator is homogeneous allogenic bone.
As can be known from the above technical solutions, the present invention, in netted sleeve pipe interplantation bone, makes bon e formation directional, increases effectively Become bone amount, it is to avoid the soft tissue in Cranial defect region enters in plant bone mass, and does not affect the entrance of bone growth factor;And by negative Be pressed in and in defective region, cause the mechanicalness of cell to uphold, promote cell and granulation tissue growth, make the cells such as tgf, vegf because Sublist reaches lifting, thus reaching the purpose of quick healing.
Brief description
Fig. 1 is the structure chart of the present invention;
Fig. 2 is the profile of negative tube in the present invention.
Specific embodiment
The present invention be discussed in detail below in conjunction with the accompanying drawings:
The bone grafting device of the present invention includes the Cranial defect area 2 being formed between two bone stumps 1, and Cranial defect area is provided with two Hold the netted sleeve pipe 3 that is connected respectively with two bone stumps, be provided with this sleeve pipe can skeletonization obturator 4, obturator preferably employs together Plant allograph bone;The present invention is provided with negative-pressure suction pipe 5, and this negative-pressure suction pipe one end is connected with vacuum suction machine 6, also can be directly connected to The vacuum suction connector of hospital, the negative-pressure suction pipe other end is inserted radially in described obturator and provides negative pressure ring for obturator skeletonization Border.In implementation process, the mesh of described netted sleeve pipe need to reach claimed below: the soft tissue in Cranial defect region must be stoped to enter Enter filling internal, bone growth factor should be made to enter obturator;In order to meet above-mentioned requirements, present invention preferably uses grenadine jacket casing Pipe, and made using pga material, this material can directly absorb in osteogenetic process.
In surgical procedure, first grenadine jacket casing pipe is placed in behind defective region, then in sleeve pipe, fills homogeneous allogenic bone, Again by negative-pressure suction pipe radially from the obturator of sleeve pipe insertion implantation, last tight suture manadesma and skin, make to bear Form certain negative pressure, subnormal ambient can make weekend tissue blood vessel fit tightly in pressure suction tube;Homogeneous allogenic bone in pga sleeve pipe Enable planted allosome skeletonization in 3 D stereo, effective one-tenth bone amount can be increased, reduce lopsided skeletonization, the subnormal ambient in sleeve pipe May also provide abundant blood fortune.
In the present invention, described negative-pressure suction pipe 5 be located at the internal paragraph of filling include tilting section 51 and with this tilting section The horizontal segment 52 of rounding off, so can facilitate negative-pressure suction pipe into and out, described horizontal segment preferably and sleeve pipe axle To parallel so that the negative pressure in sleeve pipe is more uniform, be conducive to uniform skeletonization.In implementation process, preferably in described water Several through holes 53 have all been issued, this through hole can avoid obturator by absorption tube, causes negative pressure on flat section and the tube wall of tilting section Attract blockage;Preferably, the distal end faces closing of described horizontal segment, several air-vents are issued on this Closed End 54;In implementation process, air-vent should be set as much as possible on the basis of ensureing the complete serviceability of negative-pressure suction pipe And through hole, accordingly even when the hole of a part is blocked, another part hole still can provide the subnormal ambient of skeletonization.
The present invention is implanted into homogeneous allogenic bone in pga sleeve pipe, bootable Cranial defect bone area skeletonization, increases and effectively becomes bone amount; There is provided continuous negative pressure in pga sleeve pipe simultaneously, Cranial defect bone area skeletonization can be promoted, shorten healing time;In addition, pga sleeve pipe Subnormal ambient can form poroma, i.e. skeletonization around the line of force between the far and near end cortex of bone in long diaphysis Cranial defect area.
Above-mentioned embodiment is used for illustrative purposes only, and is not limitation of the present invention, relevant technical field Those of ordinary skill, without departing from the spirit and scope of the present invention, acceptable various changes can be made and modification, therefore institute There is equivalent technical scheme also should belong to scope of the invention.

Claims (9)

1. repair large segmental bone defect bone grafting device, including the Cranial defect area being formed between two bone stumps it is characterised in that: Cranial defect area is provided with the netted sleeve pipe that two ends are connected respectively with two bone stumps, be provided with this sleeve pipe can skeletonization obturator;If There is negative-pressure suction pipe, this negative-pressure suction pipe one end is connected with vacuum suction machine, it is should in described obturator that the other end is inserted radially into Obturator skeletonization provides subnormal ambient.
2. bone grafting device according to claim 1 it is characterised in that: described sleeve pipe is made using pga material.
3. bone grafting device according to claim 2 it is characterised in that: described sleeve pipe be grenadine jacket casing pipe.
4. the bone grafting device according to claim 1 or 2 or 3 it is characterised in that: described negative-pressure suction pipe tilts described in insertion In obturator.
5. bone grafting device according to claim 4 it is characterised in that: described negative-pressure suction pipe is located at the internal paragraph of filling Horizontal segment including tilting section with this tilting section rounding off.
6. bone grafting device according to claim 5 it is characterised in that: described horizontal segment is axially in parallel with sleeve pipe.
7. bone grafting device according to claim 5 it is characterised in that: all issue on described horizontal segment and the tube wall of tilting section There are several through holes.
8. bone grafting device according to claim 5 it is characterised in that: the closing of the distal end faces of described horizontal segment, in this envelope Several air-vents have been issued on closed end face.
9. bone grafting device according to claim 4 it is characterised in that: described obturator be homogeneous allogenic bone.
CN201410539753.XA 2014-10-14 2014-10-14 Bone grafting device for repairing large segmental bone defects Active CN104323875B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410539753.XA CN104323875B (en) 2014-10-14 2014-10-14 Bone grafting device for repairing large segmental bone defects

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Application Number Priority Date Filing Date Title
CN201410539753.XA CN104323875B (en) 2014-10-14 2014-10-14 Bone grafting device for repairing large segmental bone defects

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CN104323875A CN104323875A (en) 2015-02-04
CN104323875B true CN104323875B (en) 2017-01-18

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Publication number Priority date Publication date Assignee Title
CN107028687B (en) * 2017-06-05 2019-05-31 南方医科大学 A kind of clavicle proximal end anatomical form prosthese and forming method

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* Cited by examiner, † Cited by third party
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DE4414675C1 (en) * 1994-04-27 1995-09-28 Kirsch Axel Covering device for bone defects and method for their production
DE10328892A1 (en) * 2003-06-26 2005-05-12 Curasan Ag Bone building agent and manufacturing process
NL1032851C2 (en) * 2006-11-10 2008-05-14 Fondel Finance B V Kit and method for fixing a prosthesis or part thereof and / or filling bony defects.
US20080269745A1 (en) * 2007-04-24 2008-10-30 Osteolign, Inc. Thermo-chemically activated intramedullary bone stent
GB0813659D0 (en) * 2008-07-25 2008-09-03 Smith & Nephew Fracture putty
CN101785715A (en) * 2010-03-12 2010-07-28 张纯朴 Auxiliary bone grafting bracket for large bone defect
CN201684047U (en) * 2010-05-28 2010-12-29 张纯朴 Continuous pressurizing forming mold for iliac bone reshaping
CN202236831U (en) * 2011-10-10 2012-05-30 中国人民解放军第四军医大学 Manual type negative-pressure aspirator head
CN102813564B (en) * 2012-08-23 2015-12-09 中国人民解放军第四军医大学 A kind of preparation method of titanium alloy artificial bone/intramedullary nail compression fixation system
CN203564368U (en) * 2013-11-06 2014-04-30 郭华 Rabbit long bone defect repair model fixing device
CN103830793A (en) * 2014-03-10 2014-06-04 杨雷刚 Method for fixing open bone defect by negative-pressure closed irrigation and autograft

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Address after: 410000 No. 138, Tongzi Road, Yuelu District, Hunan, Changsha

Patentee after: The Third Hospital of Central South University

Address before: 410000 No. 138, Tongzi Road, Yuelu District, Hunan, Changsha

Co-patentee before: Zhou Jiahui

Patentee before: Liu Zhendong

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