CN104288719A - 一种治疗慢性肠炎的中药组合物 - Google Patents

一种治疗慢性肠炎的中药组合物 Download PDF

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CN104288719A
CN104288719A CN201410498997.8A CN201410498997A CN104288719A CN 104288719 A CN104288719 A CN 104288719A CN 201410498997 A CN201410498997 A CN 201410498997A CN 104288719 A CN104288719 A CN 104288719A
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赵世明
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Abstract

本发明涉及一种治疗慢性肠炎的中药组合物，其中药原料及重量份配比为：党参20-40份、茯苓20-40份、白术20-40份、山药20-40份、白扁豆20-40份、莲肉20-40份、芡实20-40份、焦麦芽20-40份、焦山楂20-40份、焦神曲20-40份、陈皮5-15份、砂仁5-15份、鸡内金10-30份、炒薏苡仁20-40份、桔梗5-15份、木香5-15份、菟丝子20-40份、槐米5-15份、地榆10-20份、葛根10-20份、枳壳3-9份、干姜5-15份、泽泻10-20份、甘草3-9份。本发明的中药组合物具有健脾和胃、舒肝解郁、补中益气、涩肠止泻的功效，其治疗慢性肠炎疗效显著，作用可靠。

Description

一种治疗慢性肠炎的中药组合物
技术领域
本发明涉及一种传统草药的未确定结构的医药配制品，尤其是一种治疗慢性肠炎的中药组合物。
背景技术
慢性肠炎泛指肠道的慢性炎症性疾病，其病因可为如细菌、霉菌、病毒、原虫等微生物感染，过敏、变态反应等原因所致。另外，长期过度疲劳、情绪激动、过度精神紧张，加以营养不良，咀嚼障碍、胃酸缺乏、胃大部切除术后、肠道寄生虫病等，均可导致疾病发作。临床表现为长期慢性、或反复发作的间歇性腹部隐痛、腹胀、腹泻，遇冷、进食油腻或饮酒后以及劳累，情绪波动导致症状加重。近年来，随着人们生活水平的提高和生活方式的改变，慢性肠炎的发病率呈上升趋势，并且该病病程较长，难以根治，反复发作，严重影响着人们的身体健康和生活质量，且癌变率达5％左右。目前，临床上对于慢性肠炎的治疗是根据检查结果采取相应的措施，进行对症治疗。其治疗药物有中成药和西药，中成药可服用参苓白术散，西药可服用氟呱酸，其存在中成药治愈时间长、以及西药治标不治本，易产生抗药性，副作用大的不足。
祖国医学认为，慢性肠炎多由饮食失节、损伤脾胃、情志不畅、肝郁气滞或脾胃虚弱、中气不运所致。
根据中医理论，针对肠炎的发病机理，采用健脾和胃、舒肝理气的治法，进行辩证配伍组方，以达到标本兼治的目的。
发明内容
为了克服现有技术中中成药治疗慢性肠炎时间长、西药治疗慢性肠炎存在治标不治本及副作用大的不足，本发明提供一种配制简便、成本低、疗效显著、无副作用的治疗慢性肠炎的中药组合物。
本发明解决其技术问题所采用的技术方案是：一种治疗慢性肠炎的中药组合物，其特征在于：其中药原料及重量份配比为：党参20-40份、茯苓20-40份、白术20-40份、山药20-40份、白扁豆20-40份、莲肉20-40份、芡实20-40份、焦麦芽20-40份、焦山楂20-40份、焦神曲20-40份、陈皮5-15份、砂仁5-15份、鸡内金10-30份、炒薏苡仁20-40份、桔梗5-15份、木香5-15份、菟丝子20-40份、槐米5-15份、地榆10-20份、葛根10-20份、枳壳3-9份、干姜5-15份、泽泻10-20份、甘草3-9份。
本发明的优选技术方案是：一种治疗慢性肠炎的中药组合物，其特征在于：其中药原料及重量份配比为：党参30份、茯苓30份、白术30份、山药30份、白扁豆30份、莲肉30份、芡实30份、焦麦芽30份、焦山楂30份、焦神曲30份、陈皮10份、砂仁10份、鸡内金20份、炒薏苡仁30份、桔梗10份、木香10份、菟丝子30份、槐米10份、地榆15份、葛根15份、枳壳6份、干姜10份、泽泻15份、甘草6份。
本发明中药组合物是在传统中医理论和临床经验指导下，精选药物组方。本发明中药组合物中：党参具有补中益气、健脾益肺的功效；茯苓具有益气安神、健脾和胃、祛除湿热、行水止泄的功效；白术具有健脾益气、燥湿利水、止汗安胎的功效；山药具有健脾补肺、益胃补肾、固肾益精、聪耳明目、助五脏、强筋骨、长志安神、延年益寿的功效；白扁豆具有健脾化湿，和中消暑的功效；莲肉具有补脾止泻、养心益肾功效；芡实具有益肾固精、补脾止泻、祛湿止带的功效；焦麦芽、焦山楂、焦神曲合称焦三仙，其中焦麦芽有很好的消化淀粉类食物的作用，焦山楂善于治疗肉类或油腻过多所致的食滞，焦神曲则利于消化米面食物，三药合用，能明显地增强消化功能；陈皮具有理气健脾、调中利水、燥湿化痰的功效；砂仁具有化湿开胃，温脾止泻，理气安胎的功效；鸡内金具有消食健胃、化积排石、固摄缩尿、涩精止遗的功效；炒薏苡仁具有利水消肿、健脾去湿、舒筋除痹的功效；桔梗具有宣肺祛痰、养气补血、利五脏、补五劳的功效；木香具有行气止痛、调中导滞的功效；菟丝子具有补肾益精、养肝健脾的功效；槐米具有凉血止血、清肝泻火的功效；地榆具有凉血止血，清热解毒，消肿敛疮的功效；葛根具有发表解肌、升阳透疹、解热生津的功效；枳壳具有理气宽中、行滞消胀的功效；干姜具有温中散寒、回阳通脉、温肺化饮的功效；泽泻具有利水渗湿、泄热通淋的功用；甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明精选药物组方，其药物组分经辩证配伍，在作用上相互佐助，共奏健脾和胃、舒肝解郁、补中益气、涩肠止泻的功效，对慢性肠炎的治疗达到标本兼治。
本发明组合物的组分均采用天然的中药原料，其配制简便、药源广、成本低。本发明遵循中医的处方用药原则，各种组分药物采用水煎服用。经临床应用验证，其疗效显著可靠，药性平和，未出现毒副作用，有效率达95%，治愈率72%。
具体实施方式
下面结合实施例对本发明作进一步说明。
实施例1
一种治疗慢性肠炎的中药组合物，其中药原料及重量配比为：党参30g、茯苓30g、白术30g、山药30g、白扁豆30g、莲肉30g、芡实30g、焦麦芽30g、焦山楂30g、焦神曲30g、陈皮10g、砂仁10g、鸡内金20g、炒薏苡仁30g、桔梗10g、木香10g、菟丝子30g、槐米10g、地榆15g、葛根15g、枳壳6g、干姜10g、泽泻15g、甘草6g。
实施例2
一种治疗慢性肠炎的中药组合物，其中药原料及重量配比为：党参20g、茯苓40g、白术20g、山药40g、白扁豆20g、莲肉40g、芡实20g、焦麦芽40g、焦山楂20g、焦神曲40g、陈皮5g、砂仁15g、鸡内金10g、炒薏苡仁40g、桔梗5g、木香15g、菟丝子20g、槐米15g、地榆10g、葛根20g、枳壳3g、干姜15g、泽泻10g、甘草9g。
实施例3
一种治疗慢性肠炎的中药组合物，其中药原料及重量配比为：党参40g、茯苓20g、白术40g、山药20g、白扁豆40g、莲肉20g、芡实40g、焦麦芽20g、焦山楂40g、焦神曲20g、陈皮15g、砂仁5g、鸡内金30g、炒薏苡仁20g、桔梗15g、木香5g、菟丝子40g、槐米5g、地榆20g、葛根10g、枳壳9g、干姜5g、泽泻20g、甘草3g。
实施例4
一种治疗慢性肠炎的中药组合物，其中药原料及重量配比为：党参25g、茯苓35g、白术25g、山药35g、白扁豆25g、莲肉35g、芡实25g、焦麦芽35g、焦山楂25g、焦神曲35g、陈皮8g、砂仁13g、鸡内金15g、炒薏苡仁35g、桔梗8g、木香13g、菟丝子25g、槐米13g、地榆12g、葛根18g、枳壳4g、干姜13g、泽泻12g、甘草8g。
实施例5
一种治疗慢性肠炎的中药组合物，其中药原料及重量配比为：党参35g、茯苓25g、白术35g、山药25g、白扁豆35g、莲肉25g、芡实35g、焦麦芽25g、焦山楂35g、焦神曲25g、陈皮13g、砂仁8g、鸡内金25g、炒薏苡仁25g、桔梗13g、木香8g、菟丝子35g、槐米8g、地榆18g、葛根12g、枳壳8g、干姜8g、泽泻18g、甘草4g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下：将组方的中药原料放入容器中，加冷水漫过药面，浸泡15～20分钟，再加水没过药面约6厘米，进行第一次煎煮，未沸前采用武火煎煮，沸后用文火煎煮20～30分钟；第二次煎煮，加水没过药面约4厘米，水沸后煎煮15～20分钟。两次煎煮取汁，合并。
本发明以实施例1所给出的一种治疗慢性肠炎的中药组合物，做临床疗效总结如下：
一、一般性资料：本中药组合物应用于临床观察病例100例，男46例，女54例，年龄20～75岁。
二、诊断依据：
(1)有暴饮暴食或吃不洁腐败变质食物史；
(2)恶心、呕吐频繁，腹痛，频繁腹泻，多为水样便，可含有未消化食物，少量粘液，甚至血液等；
(3)常有发热、头痛、全身不适及程度不同的中毒症状；
(4)呕吐、腹泻严重者，可有脱水、酸中毒，甚至休克等；
(5)体征不明显，上腹及脐周有压痛，无肌紧张及反跳痛，肠鸣音多亢进。
三、用法用量：临床应用时，一日一剂，水煎两遍取汁约400ml，分早、晚两次温服。六天为一疗程。治疗期间忌生冷辛辣刺激之物。
四、疗效标准：
(1)治愈：腹痛、腹泻、大便不成形等临床症状体征消失，功能活动恢复正常；
(2)显效：临床症状体征基本或大部分消失；
(3)有效：临床症状明显好转；
(4)无效：临床症状体征无改善。 
五、治疗效果：该临床观察病例中，服药2-8个疗程，痊愈72例，随访未见复发；显效15例，有效8例，无效5例。治疗期间未发生毒副作用。
六、典型病例：
病例1：张某，男，46 岁。长期饮食不规律，导致慢性肠炎，工作劳累经常腹痛、腹泻，每日大便最少4次，多达10次。服用多种药物治疗，但均效果不佳。服用本发明中药组合物制备的药剂1个疗程，病情明显好转；腹泻次数明显减少；继续服用1个疗程，腹泻停止，巩固1个疗程后，痊愈。
病例2：孙某，女，55 岁。患慢性肠炎已多年，面色不华、精神不振，喜温怕冷，每日大便次数4-6次，大便如水。服用本发明中药组合物制备的药剂3个疗程，大便成型，精神变好；继续服用2个疗程，治愈，喜温怕冷症状消失，面部泛红，身体强健，饮食有规律。

Claims (2)

1. 一种治疗慢性肠炎的中药组合物，其特征在于：其中药原料及重量份配比为：党参20-40份、茯苓20-40份、白术20-40份、山药20-40份、白扁豆20-40份、莲肉20-40份、芡实20-40份、焦麦芽20-40份、焦山楂20-40份、焦神曲20-40份、陈皮5-15份、砂仁5-15份、鸡内金10-30份、炒薏苡仁20-40份、桔梗5-15份、木香5-15份、菟丝子20-40份、槐米5-15份、地榆10-20份、葛根10-20份、枳壳3-9份、干姜5-15份、泽泻10-20份、甘草3-9份。
2.根据权利要求1所述的一种治疗慢性肠炎的中药组合物，其特征在于：其中药原料及重量份配比为：党参30份、茯苓30份、白术30份、山药30份、白扁豆30份、莲肉30份、芡实30份、焦麦芽30份、焦山楂30份、焦神曲30份、陈皮10份、砂仁10份、鸡内金20份、炒薏苡仁30份、桔梗10份、木香10份、菟丝子30份、槐米10份、地榆15份、葛根15份、枳壳6份、干姜10份、泽泻15份、甘草6份。
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