CN104288641A - 治疗美尼氏综合症的中药 - Google Patents

治疗美尼氏综合症的中药 Download PDF

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CN104288641A
CN104288641A CN201410491512.2A CN201410491512A CN104288641A CN 104288641 A CN104288641 A CN 104288641A CN 201410491512 A CN201410491512 A CN 201410491512A CN 104288641 A CN104288641 A CN 104288641A
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吴义娟
王力力
孙孝红
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Abstract

本发明涉及中药配方领域，具体地说是一种治疗美尼氏综合症的中药，其特征在于由如下重量百分比的原料药制成，钩藤6～9％，蔓荆子4～7％，苻神6～9％，藁本4～7％，狗狗秧6～9％，决明子3～5％，佩兰10～13％，柴胡0.1～0.2％，梗通草10～13％，千只眼3～6％，甘遂3～5％，夏枯草2～5％，桑寄生3～6％，午香草3～6％，益智仁4～6％，紫苑花2～5％，八月札2～4％，仙鹤草2～4％，将上述原料药用水浸泡，煎熬后去渣得滤液。本发明成本低，无毒副作用，疗效显著。

Description

治疗美尼氏综合症的中药
技术领域
本发明涉及一种中成药制剂，具体地说是一种治疗美尼氏综合症的中药。
背景技术
众所周知，美尼尔氏综合症，中医称为耳源性眩晕症，属“眩晕”范畴。祖国医学认为，眩晕症可由风、痰、湿、虚引起，故有“无风不作眩”、“无痰不作眩”、“无虚不作眩”的说法。它是一种不分男、女、老、幼都可患之的常见病症，病人一旦犯病，感觉非常痛苦。迄今为止尚无特效疗法及特效药物，现有的治疗方法及药物只能暂时缓解和控制病情，但不能彻底根治此病。病人在遇上诱发此病的病因时就会旧病复发，这样长年累月反反复复，给患者造成了极大的痛苦，同时也给家人带来了很大的麻烦。
发明内容
本发明的目的就是为了克服上述现有的技术不足，提供一种治疗美尼氏综合症的中药，成本低，无毒副作用，疗效显著。
本发明解决上述技术问题采用的技术方案是：一种治疗美尼氏综合症的中药，其特征在于由如下重量百分比的原料药制成，钩藤6～9％，蔓荆子4～7％，苻神6～9％，藁本4～7％，狗狗秧6～9％，决明子3～5％，佩兰10～13％，柴胡0.1～0.2％，梗通草10～13％，千只眼3～6％，甘遂3～5％，夏枯草2～5％，桑寄生3～6％，午香草3～6％，益智仁4～6％，紫苑花2～5％，八月札2～4％，仙鹤草2～4％，将上述原料药用水浸泡，煎熬后去渣得滤液。
本发明的有益效果是，成本低，无毒副作用，疗效显著。
具体实施方式
下面结合实施例对本发明作进一步的描述：
实施例1：
采用钩藤、蔓荆子、苻神、藁本、狗狗秧、决明子、佩兰、柴胡、梗通草、千只眼、甘遂、夏枯草、桑寄生、午香草、益智仁、紫苑花、八月札、仙鹤草为原料药制备而成。其组分(重量％)每副为钩藤8.3、蔓荆子6.2、苻神8.1、藁本6.1、狗狗秧8.1、决明子4.6、佩兰10.8、柴胡0.2、梗通草11.3、千只眼4.4、甘遂4.6、夏枯草3.9、桑寄生4.4、午香草4.9、益智仁4.3、紫苑花3.9、八月札3.1、仙鹤草2.8。取上述18味中草药原料，总重量为202克，加水1100～1300ml，浸泡2～3小时，然后用武火煮沸，文火煎熬60～70分钟，去渣得滤液200ml左右，药渣再加水300～400ml，煎熬30分钟左右，去渣得滤液100ml左右，共得300ml左右药汁，装入无菌玻璃瓶内，密封瓶盖备用。每日1剂分2次口服，每次空腹服150ml左右。
本发明钩藤清热平肝，熄风定惊。治小儿惊痫瘈疭，大人血压偏高，头晕、目眩，妇人子痫；蔓荆子疏散风热，清利头目，除湿处关节。主治外感头痛，偏正头风，昏晕目暗，赤眼多泪，目睛内痛，齿龈肿痛，湿痹拘挛；苻神有渗湿、健脾、宁心等功能。用于痰饮、水肿、小便不利、泄泻、心悸、眩晕，共为方中君药；藁本具有祛风散寒，除湿止痛的功效，主治风寒头痛，头风偏痛，目昏鼻塞，齿痛牙宣，风湿痹痛，寒湿腹痛泄泻；狗狗秧清肝热，滋阴，利小便。主肝阳上亢，头晕，目眩，小便不利，二味相伍助君药，为方中臣药；佐以决明子清热明目，润肠通便。用于目赤涩痛，羞明多泪，头痛眩晕，目暗不明，大便秘结；佩兰感受暑湿，寒热头痛，湿润内蕴，脘痞不饥，恶心呕吐，口中甜腻，消洵。用于湿浊中阻，脘痞呕恶，口中甜腻，口臭，多涎，暑湿表症，头胀胸闷；柴胡有和解表里，疏肝，升阳之功效。用于感冒发热、寒热往来、疟疾、肝郁气滞、胸肋胀痛、脱肛、子宫脱垂、月经不调；梗通草通肠利便，退热止渴。治鼻塞，明目，通关节；千只眼祛风解表，行气止痛，活血散瘀。用于感冒发热，支气管炎，哮喘，风湿麻木，筋骨疼痛，跌打瘀血肿痛，皮肤瘙痒，湿疹，毒蛇咬伤，疟疾，胃痛，水肿等；甘遂水肿，腹水，留饮结胸，癫痫，喘咳，大小便不通；夏枯草具有清泄肝火、散结消肿、清热解毒、祛痰止咳、凉血止血的功效，适用于淋巴结核、甲状腺肿、乳痈、头目眩晕、口眼歪斜、筋骨疼痛、肺结核、血崩、带下、急性传染性黄疸型肝炎及细菌性痢疾等；桑寄生补肝肾，强筋骨，除风湿，通经络，益血，安胎。治腰膝酸痛，筋骨痿弱，偏枯，脚气，风寒湿痹，胎漏血崩，产后乳汁不下；午香草消炎止痛，健胃行气。治扁桃体炎，急牲胃肠炎，膀胱炎，尿道炎，小儿疳积；益智仁脾胃虚寒，呕吐，泄泻，腹中冷育，口多唾涎，肾虚遗尿，尿频，遗精，白浊，多唾液等症；紫苑花润肺下气，消痰止咳。主治：痰多喘咳，新久咳嗽，劳嗽咳血；八月札舒肝理气，活血止痛，除烦利尿。治肝胃气痛，胃热食呆，烦渴，亦白痢疾，腰痛，胁痛，疝气，窟经，子宫下坠；仙鹤草止血，截疟，止痢，解毒。用于咳血、吐血、治流鼻血有特效、疟疾、脱力劳伤、痈肿，共为方中使药。18种中草药巧妙组方，药物相互协调作用，共奏美尼氏综合症之功效。
本发明各原料还可按下表所列比例(重量百分比)混合的实施例来实现，其煎熬程序、口服方法与实施例1相同，其含量如下表所示。
下面结合我院进行的临床试验对本发明作进一步详细地描述：
1、病例选择：对300例患者进行临床观察治疗，其中男性150例，女性150例，年龄30-70岁，均诊断为美尼尔氏综合症。
2、诊断标准：中医诊断标准参照标准国家中医药管理局发布的《中医病证诊断疗效标准》。
3、治疗方法：口服实施例1中制得的汤剂，每日一剂，15天为一疗程，连续服用3个疗程。
4、疗效判断：治愈：临床症状体征消失，功能活动恢复正常。显效：临床症状体征基本或大部分消失。有效：临床症状明显好转或好转。无效：临床症状体征无改善。
治疗效果：临床治愈295例，治愈率98.33％；显效3例，显效率1％；有效1例，有效率0.33％，无效1例，无效率0.33％；总有效率99.67％。
典型病例
胡某，男，46岁，来我院就诊。患者自述，突然犯病、眩晕，视物体旋转，厌食、耳鸣、四肢软弱无力，稍改变体位眩晕乃加重。诊断为美尼尔氏综合症，连续服用本发明药物3个疗程(每日一剂，水煎服，15天为1个疗程)后，痊愈，再继续服用1个疗程以巩固疗效，一年后随访未再复发。
张某，女，42岁。患者自述，常头晕、耳鸣、恶心呕吐，之前采用中西医治疗未能痊愈，劳累过度则病情复发。诊断为美尼尔氏综合症，连续服用本发明汤剂2个疗程后，痊愈，再继续服用1疗程以巩固疗效，一年后随访未再复发。

Claims (1)

1.一种治疗美尼氏综合症的中药，其特征在于：由如下重量百分比的原料药制成，钩藤6～9％，蔓荆子4～7％，苻神6～9％，藁本4～7％，狗狗秧6～9％，决明子3～5％，佩兰10～13％，柴胡0.1～0.2％，梗通草10～13％，千只眼3～6％，甘遂3～5％，夏枯草2～5％，桑寄生3～6％，午香草3～6％，益智仁4～6％，紫苑花2～5％，八月札2～4％，仙鹤草2～4％，将上述原料药用水浸泡，煎熬后去渣得滤液。
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1634516A (zh) * 2004-12-13 2005-07-06 张兴仕 一种治疗美尼尔氏综合征的药物组合物及其制备方法
CN103191314A (zh) * 2013-04-08 2013-07-10 丁见 一种治疗美尼尔氏综合症的中药组合物
CN104013847A (zh) * 2014-06-16 2014-09-03 孙喜范 一种治疗梅尼埃病中药

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1634516A (zh) * 2004-12-13 2005-07-06 张兴仕 一种治疗美尼尔氏综合征的药物组合物及其制备方法
CN103191314A (zh) * 2013-04-08 2013-07-10 丁见 一种治疗美尼尔氏综合症的中药组合物
CN104013847A (zh) * 2014-06-16 2014-09-03 孙喜范 一种治疗梅尼埃病中药

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Application publication date: 20150121