CN104286872A - Natural enteric maca preparation and production method thereof - Google Patents
Natural enteric maca preparation and production method thereof Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to a natural enteric maca preparation and a production method thereof. The natural enteric maca preparation is prepared from the following raw materials in parts by weight: 30-70 parts of maca powder, 5-8 parts of bletilla striata powder, 2-5 parts of konjac powder, 2-6 parts of yam powder, 6-12 parts of pueraria powder and 5-10 parts of semen euryales powder. The production method sequentially comprises the following steps: preparing maca extracting solution, bletilla striata extracting solution, konjac extracting solution, yam extracting solution, pueraria extracting solution and semen euryales extracting solution, mixing the extracting solution to obtain a mixed solution, homogenizing, and carrying out spray-drying to obtain mixed powder; tabletting to obtain enteric maca tablets; or directly packing the mixed powder to obtain enteric maca powder; and filling the mixed powder to obtain hard capsules. The natural enteric maca preparation adopts a scientific and unique formula, not only cannot influence the quality of an original maca product, and also is beneficial to human health and is purely natural.
Description
Technical field
The present invention relates to a kind of agate coffee enteric coated preparations and production method thereof, particularly relate to a kind of natural enteric agate coffee preparation and production method thereof.
Background technology
Agate coffee is the separate row Vegetable spp plateau plant of introducing a fine variety from Peru, have antifatigue, improve sperm motility, improve climacteric metancholia and rheumatism symptom, improve the functions such as memory, it is warm in nature, returns stomach, lung, kidney channel, edible agate coffee product often causes stomach energy, causes and has a stomach upset.
Enteric coated preparations, is in order to some is had stimulation to stomach, can injures the preparation of stomach lining, not absorb under one's belt, and in small intestine solution absorption, avoid preparation to cause harmful effect to stomach.Present enteric coated preparations is generally the mode adopting enteric coating, the concept of enteric coating (enteric coating) just occurred before more than 130 years, its clothing film stomach juice-resistant, the rapid disintegration of energy after entering intestines a part also discharges content, thus plays drug effect.The mechanism of action of enteric polymer is its different solubility in different pH media, namely keeps complete when low pH, and the stripping discharge medicine when higher pH.Enteric coating belongs to delayed release dosage forms (delayed release forms), its object mainly: avoid medicine to be subject to the destruction of enzyme or hydrochloric acid in gastric juice in stomach, make interior bag thing at intestinal absorption; Avoid medicine to produce intense stimulus to stomach lining, cause nausea, the bad reaction such as vomiting.
At present, the enteric material of existing more than 100 kinds is studied and use, mainly contain the kinds such as shellac, PVAP (PVAP), crylic acid resin (polyacrylic resin), acrylic resin is the coating material of extensive use both at home and abroad at present.Effect is waited in order to anti-stick, enteric coating formula can add the materials such as talcum powder, titanium dioxide, monoglyceride, tween toward contact, although these materials add harmless on a small quantity, but to human body also without benefit, if adopted by agate coffee product the mode of enteric coating to enter intestines release be unfavorable for health, product can not reach natural free of contamination degree.
Also disclose some agate coffee preparations now, if publication date is on 04 04th, 2007, publication number is in the Chinese patent of CN1939387, disclose a kind of compound Sanchi preparation, this compound Sanchi preparation by 20 ~ 50% Radix Notoginseng powder, 25 ~ 60% pueraria root powders and 10 ~ 45% kudzu-vine root powder mix, it has the function for the treatment of cerebral thrombus, cerebral hemorrhage and prevention cardiovascular and cerebrovascular disease, and does not belong to enteric coated preparations.And for example publication date is on 01 08th, 2014, publication number is in the Chinese patent of CN103494209A, disclose a kind of Maca composite health care medicine, this Maca composite health care medicine is made up of pueraria root powder, testiset penis phocae, donkey-hide gelatin, oyster, the tuber of dwarf lilyturf, the root of three-nerved spicebush, matrimony vine, the fruit of Chinese magnoliavine, activated calcium powder, and this Maca composite health care medicine does not also belong to enteric coated preparations.For another example publication date is on 02 12nd, 2014, publication number is in the Chinese patent of CN103566046A, disclose a kind of Chinese medicine preparation containing agate coffee, following raw material should be contained: agate coffee containing the Chinese medicine preparation of agate coffee, ginseng, the fruit of Chinese wolfberry, Chinese cassia tree, hawthorn, cassia seed and lotus leaf, wherein, with the agate coffee of 100 weight portions for benchmark, the content of each raw material is separately: ginseng 20-40 weight portion, fruit of Chinese wolfberry 20-40 weight portion, Chinese cassia tree 10-20 weight portion, hawthorn 5-10 weight portion, cassia seed 5-10 weight portion, lotus leaf 5-10 weight portion, this Chinese medicine preparation does not also belong to enteric coated preparations.
In sum, also there is no a kind of scientific formulation, uniqueness at present, neither affect the quality of original agate coffee product, be conducive to health again, pure natural, do not add resin, the natural enteric agate coffee preparation of glue class synthetic membrane clothing material and production method thereof.
Summary of the invention
The object of the invention is to overcome above shortcomings in prior art, and a kind of scientific formulation, uniqueness are provided, neither affect the quality of original agate coffee product, be conducive to health again, pure natural, does not add resin, the natural enteric agate coffee preparation of glue class synthetic membrane clothing material and production method thereof.
The present invention's adopted technical scheme that solves the problem is: the feature of this natural enteric agate coffee preparation is: said preparation is made up of the raw material of following parts by weight: pueraria root powder 30 ~ 70 parts, 5 ~ 8 parts, bletilla striata powder, konjaku flour 2 ~ 5 parts, yam flour 2 ~ 6 parts, kudzuvine root starch 6 ~ 12 parts, gorgon euryale seed powder 5 ~ 10 parts.Make compatibility science, the uniqueness of natural enteric agate coffee preparation of the present invention thus, each raw material cooperative compensating, make preparation have good antifatigue, improve sperm motility, improve climacteric metancholia and rheumatism symptom, improve the functions such as memory, and can not stomach energy be caused after eating, can not cause and have a stomach upset.
As preferably, pueraria root powder of the present invention adopt volumn concentration be 70% ethanolic solution extract, described bletilla striata powder, konjaku flour, yam flour, kudzuvine root starch and gorgon euryale seed powder all adopt volumn concentration be 50% ethanolic solution extract.
A production method for natural enteric agate coffee preparation, its feature is: described production method is made up of the raw material of following parts by weight: pueraria root powder 30 ~ 70 parts, 5 ~ 8 parts, bletilla striata powder, konjaku flour 2 ~ 5 parts, yam flour 2 ~ 6 parts, kudzuvine root starch 6 ~ 12 parts, gorgon euryale seed powder 5 ~ 10 parts; This production method is made up of following steps successively:
(1) pueraria root powder use volumn concentration is the ethanolic solution extraction of 70%, obtains agate coffee extract; Bletilla striata powder, konjaku flour, yam flour, kudzuvine root starch and gorgon euryale seed powder all adopt volumn concentration be 50% ethanolic solution extract, obtain bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract respectively; Agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract are all in 35 DEG C of temperature, and 10KPa vacuum under pressure concentrates, and the volumn concentration being concentrated into ethanol is 10% ~ 12%;
(2) by agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and the Gorgon fruit extract mixing after concentrated, obtain mixed liquor, mixed liquor is added in homogenizer, first homogeneous three times under 40MPa pressure, then homogeneous is once under 4.5MPa pressure;
(3) by the spraying dry under nitrogen protection of the mixed liquor after homogeneous, mixed-powder is obtained;
(4) by mixed-powder compressing tablet, enteric Maca tablet is obtained; Or mixed-powder is directly packed, obtain the agent of enteric pueraria root powder; Or by filling for mixed-powder one-tenth hard shell capsules.
Make production method in the present invention very simple thus, convenient operation, production process is energy-conservation, green, environmental protection, under the prerequisite of not adding resin, glue class synthetic membrane clothing material, make the enteric coated preparations being conducive to health, pure natural, overcome the technology prejudice of those skilled in the art.
As preferably, the present invention is for extracting 4-6 times that the weight of the ethanolic solution of pueraria root powder is pueraria root powder weight, for extracting 4-6 times that the weight of the ethanolic solution of bletilla striata powder is bletilla striata grain weight amount, for extracting 4-6 times that the weight of the ethanolic solution of konjaku flour is konjaku flour weight, for extracting 4-6 times that the weight of the ethanolic solution of yam flour is yam flour weight, for extracting 4-6 times that the weight of the ethanolic solution of kudzuvine root starch is kudzuvine root starch weight, for extracting 4-6 times that the weight of the ethanolic solution of gorgon euryale seed powder is gorgon euryale seed powder weight.
As preferably, in step of the present invention (1), pueraria root powder use volumn concentration be 70% the ultrasonic extraction of ethanolic solution three times, obtain agate coffee extract.
As preferably, in step of the present invention (1), bletilla striata powder, konjaku flour, yam flour, kudzuvine root starch and gorgon euryale seed powder all adopt volumn concentration be 50% the ultrasonic extraction of ethanolic solution three times, obtain bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract respectively.
As preferably, the present invention is for extracting 5 times that the weight of the ethanolic solution of pueraria root powder is pueraria root powder weight, for extracting 5 times that the weight of the ethanolic solution of bletilla striata powder is bletilla striata grain weight amount, for extracting 5 times that the weight of the ethanolic solution of konjaku flour is konjaku flour weight, for extracting 5 times that the weight of the ethanolic solution of yam flour is yam flour weight, for extracting 5 times that the weight of the ethanolic solution of kudzuvine root starch is kudzuvine root starch weight, for extracting 5 times that the weight of the ethanolic solution of gorgon euryale seed powder is gorgon euryale seed powder weight.
The present invention compared with prior art, have the following advantages and effect: 1. adopt the content of starch such as the bletilla striata, konjaku, Chinese yam, the root of kudzu vine and Gorgon fruit higher, have protect stomach function food and medicament dual-purpose Chinese medicine water-alcohol extraction as coating agent, to Maca extract mixing parcel, spraying dry, make natural intestine solubility preparation, avoid Maca extract to the spread effect of stomach.2. adopt the bletilla striata, konjaku, Chinese yam, the root of kudzu vine and Semen euryales extract as coating agent, both can play package action, in its extract, the function composition such as flavones, alkaloid, polysaccharide can play humidification to the nutritive value of Maca extract again.3. the present invention directly can produce pulvis, filling hard capsule or produce tablet, without the need to adding any additive and auxiliary material, ensure that the natural pollution-free of product.4. compatibility science, uniqueness, each raw material cooperative compensating, has good antifatigue, improves sperm motility, improves climacteric metancholia and rheumatism symptom, improves the functions such as memory, and can not cause stomach energy after eating, can not cause and have a stomach upset.5., under the prerequisite of not adding resin, glue class synthetic membrane clothing material, made the enteric coated preparations being conducive to health, pure natural, overcome the technology prejudice of those skilled in the art.6. the technique of production method of the present invention is very simple, and convenient operation, production process is energy-conservation, green, environmental protection.
Detailed description of the invention
Below by embodiment, the present invention is described in further detail, and following examples are explanation of the invention and the present invention is not limited to following examples.
Embodiment 1.
In the present embodiment, the production method of natural enteric agate coffee preparation is made up of following steps successively.
(1) dry pueraria root powder 70 kilograms is taken, add the edible ethanol solution 350 kilograms that volumn concentration is 70%, ultrasonic extraction three times, namely first add the edible ethanol solution 350 kilograms that volumn concentration is 70%, 1. ultrasonic extraction once, obtains agate coffee extract; Then add the edible ethanol solution 350 kilograms that volumn concentration is 70%, 2. ultrasonic extraction once, obtains agate coffee extract; Add the edible ethanol solution 350 kilograms that volumn concentration is 70% again, 3. ultrasonic extraction once, obtains agate coffee extract, and said process is the process of ultrasonic extraction three times.After ultrasonic extraction three times, mixing agate coffee extract 1., agate coffee extract 2. with agate coffee extract 3., obtain agate coffee extract 1000 kilograms.
(2) 5 kilograms, dry bletilla striata powder, konjaku flour 5 kilograms, yam flour 5 kilograms, kudzuvine root starch 8 kilograms and gorgon euryale seed powder 5 kilograms is taken, the volumn concentration adding five times of weight is respectively the edible ethanol solution of 50%, ultrasonic extraction three times, namely the volumn concentration adding 25 kilograms, 25 kilograms, 25 kilograms, 40 kilograms and 25 kilograms is respectively the edible ethanol solution of 50%, ultrasonic extraction once, obtain respectively bletilla striata extract 1., konjaku extract 1., Chinese yam extract 1., root of kudzu vine extract 1. with Gorgon fruit extract 1.; Then the volumn concentration adding 25 kilograms, 25 kilograms, 25 kilograms, 40 kilograms and 25 kilograms is respectively the edible ethanol solution of 50%, ultrasonic extraction once, obtain respectively bletilla striata extract 2., konjaku extract 2., Chinese yam extract 2., root of kudzu vine extract 2. with Gorgon fruit extract 2.; The volumn concentration adding 25 kilograms, 25 kilograms, 25 kilograms, 40 kilograms and 25 kilograms is more respectively the edible ethanol solution of 50%, ultrasonic extraction once, obtain respectively bletilla striata extract 3., konjaku extract 3., Chinese yam extract 3., root of kudzu vine extract 3. with Gorgon fruit extract 3., said process is the process of ultrasonic extraction three times.After ultrasonic extraction three times, mixing bletilla striata extract 1., bletilla striata extract 2. with bletilla striata extract 3., obtain bletilla striata extract 76 kilograms; Mixing konjaku extract 1., konjaku extract 2. with konjaku extract 3., obtain konjaku extract 76 kilograms; Mixing Chinese yam extract 1., Chinese yam extract 2. with Chinese yam extract 3., obtain Chinese yam extract 75 kilograms; Mixing root of kudzu vine extract 1., root of kudzu vine extract 2. with root of kudzu vine extract 3., obtain root of kudzu vine extract 122 kilograms; Mixing Gorgon fruit extract 1., Gorgon fruit extract 2. with Gorgon fruit extract 3., obtain Gorgon fruit extract 76 kilograms.
(3) respectively by 1000 kilograms of agate coffee extracts, 76 kilograms of bletilla striata extracts, 76 kilograms of konjaku extracts, 75 kilograms of Chinese yam extracts, 122 kilograms of root of kudzu vine extracts and 76 kilograms of Gorgon fruit extracts in 35 DEG C of temperature, under 10KPa pressure, carry out Vacuum Concentration, the volumn concentration being concentrated into ethanol is 10%, obtains 425 kilograms of agate coffees extraction concentrates respectively, 42 kilograms of bletilla striata extraction concentrates, 42 kilograms of konjaku extraction concentrates, 41 kilograms of Chinese yam extraction concentrates, 74 kilograms of roots of kudzu vine extract concentrate and 42 kilograms of Gorgon fruits extraction concentrates.
(4) 425 kilograms of agate coffees in step (3) are extracted concentrate, 42 kilograms of bletilla striata extraction concentrates, 42 kilograms of konjaku extraction concentrates, 41 kilograms of Chinese yams extraction concentrates, 74 kilograms of root of kudzu vine extraction concentrates and 42 kilograms of Gorgon fruits extract concentrate and mix, obtain 666 kilograms of mixed liquors, mixed liquor is joined in homogenizer, prior to homogeneous under 40MPa pressure three times, then homogeneous is once under 4.5MPa pressure.
(5) by the spraying dry under nitrogen protection of the mixed liquor after homogeneous, mixed-powder 23 kilograms is obtained.
(6) mixed-powder that spraying dry obtains is carried out filling, obtain natural enteric agate coffee hard shell capsules.
Embodiment 2.
In the present embodiment, the production method of natural enteric agate coffee preparation is made up of following steps successively.
(1) take dry pueraria root powder 500 kilograms, add the edible ethanol solution 2500 kilograms that volumn concentration is 70%, ultrasonic extraction three times, obtain agate coffee extract 7400 kilograms.
(2) 80 kilograms, dry bletilla striata powder, konjaku flour 50 kilograms, yam flour 60 kilograms, kudzuvine root starch 100 kilograms and gorgon euryale seed powder 100 kilograms is taken, the volumn concentration adding five times of weight is respectively the edible ethanol solution of 50%, ultrasonic extraction three times, obtain bletilla striata extract 1230 kilograms respectively, konjaku extract 760 kilograms, Chinese yam extract 920 kilograms, root of kudzu vine extract 1520 kilograms, Gorgon fruit extract 1520 kilograms.
(3) bletilla striata extract in step (2), konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract are all placed in 35 DEG C of temperature, under the vacuum of 10KPa pressure, the volumn concentration being concentrated into ethanol is 10%, obtains 3000 kilograms of agate coffees extraction concentrates respectively, 740 kilograms of bletilla striata extraction concentrates, 460 kilograms of konjaku extraction concentrates, 370 kilograms of Chinese yam extraction concentrates, 900 kilograms of roots of kudzu vine extract concentrate and 900 kilograms of Gorgon fruits extraction concentrates.
(4) 3000 kilograms of agate coffees in step (3) are extracted concentrate, 740 kilograms of bletilla striata extraction concentrates, 460 kilograms of konjaku extraction concentrates, 370 kilograms of Chinese yams extraction concentrates, 900 kilograms of root of kudzu vine extraction concentrates and 900 kilograms of Gorgon fruits extract concentrate and mix, obtain 6370 kilograms of mixed liquors, join in homogenizer, prior to homogeneous under 40MPa pressure three times, then homogeneous is once under 4.5MPa pressure.
(5) by the spraying dry under nitrogen protection of the mixed liquor after homogeneous, mixed-powder 160 kilograms is obtained.
(6) by the mixed-powder direct tablet compressing that spraying dry obtains, natural enteric Maca tablet is obtained.
Embodiment 3.
In the present embodiment, the production method of natural enteric agate coffee preparation is made up of the raw material of following parts by weight: pueraria root powder 30 ~ 70 parts, 5 ~ 8 parts, bletilla striata powder, konjaku flour 2 ~ 5 parts, yam flour 2 ~ 6 parts, kudzuvine root starch 6 ~ 12 parts, gorgon euryale seed powder 5 ~ 10 parts.This production method is made up of following steps successively.
(1) pueraria root powder use volumn concentration is the ethanolic solution extraction of 70%, obtains agate coffee extract; Bletilla striata powder, konjaku flour, yam flour, kudzuvine root starch and gorgon euryale seed powder all adopt volumn concentration be 50% ethanolic solution extract, obtain bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract respectively; Agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract are all in 35 DEG C of temperature, and 10KPa vacuum under pressure concentrates, and the volumn concentration being concentrated into ethanol is 10% ~ 12%.
(2) by agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and the Gorgon fruit extract mixing after concentrated, obtain mixed liquor, mixed liquor is added in homogenizer, first homogeneous three times under 40MPa pressure, then homogeneous is once under 4.5MPa pressure.First use elevated pressures (40MPa) homogeneous three times, the large particulate matter such as residual dietary fiber, fat globule, polysaccharide in mixed liquor is broken into small particle, use lower pressure (4.5MPa) homogeneous more once, prevent fine particle adhesion in mixed liquor agglomerating, affect product characteristics.
(3) by the spraying dry under nitrogen protection of the mixed liquor after homogeneous, mixed-powder is obtained.
(4) by mixed-powder compressing tablet, enteric Maca tablet is obtained; Or mixed-powder is directly packed, obtain the agent of enteric pueraria root powder; Or by filling for mixed-powder one-tenth hard shell capsules.Thus obtained natural enteric agate coffee preparation, scientific formulation, the uniqueness of this natural enteric agate coffee preparation, neither affect the quality of original agate coffee product, be conducive to health again, and can not cause stomach energy after eating, and can not cause and have a stomach upset.
Under normal circumstances, in step (1), for extracting 4-6 times that the weight of the ethanolic solution of pueraria root powder is pueraria root powder weight, be preferably 5 times; For extracting 4-6 times that the weight of the ethanolic solution of bletilla striata powder is bletilla striata grain weight amount, be preferably 5 times; For extracting 4-6 times that the weight of the ethanolic solution of konjaku flour is konjaku flour weight, be preferably 5 times; For extracting 4-6 times that the weight of the ethanolic solution of yam flour is yam flour weight, be preferably 5 times; For extracting 4-6 times that the weight of the ethanolic solution of kudzuvine root starch is kudzuvine root starch weight, be preferably 5 times; For extracting 4-6 times that the weight of the ethanolic solution of gorgon euryale seed powder is gorgon euryale seed powder weight, be preferably 5 times.In step (1), pueraria root powder use volumn concentration be 70% the ultrasonic extraction of ethanolic solution three times, obtain agate coffee extract, bletilla striata powder, konjaku flour, yam flour, kudzuvine root starch and gorgon euryale seed powder all adopt volumn concentration be 50% the ultrasonic extraction of ethanolic solution three times, obtain bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract respectively.
Embodiment 4.
In the present embodiment, the production method of natural enteric agate coffee preparation is made up of the raw material of following parts by weight: pueraria root powder 40 parts, 8 parts, bletilla striata powder, konjaku flour 3 parts, yam flour 4 parts, kudzuvine root starch 7 parts, gorgon euryale seed powder 6 parts.This production method is made up of following steps successively.
(1) pueraria root powder use volumn concentration is the ethanolic solution extraction of 70%, for extracting 5 times that the weight of the ethanolic solution of pueraria root powder is pueraria root powder weight, ultrasonic extraction three times, obtains agate coffee extract.Bletilla striata powder, konjaku flour, yam flour, kudzuvine root starch and gorgon euryale seed powder all adopt volumn concentration be 50% ethanolic solution extract, for extracting 5 times that the weight of the ethanolic solution of bletilla striata powder is bletilla striata grain weight amount, for extracting 5 times that the weight of the ethanolic solution of konjaku flour is konjaku flour weight, for extracting 5 times that the weight of the ethanolic solution of yam flour is yam flour weight, for extracting 5 times that the weight of the ethanolic solution of kudzuvine root starch is kudzuvine root starch weight, for extracting 5 times that the weight of the ethanolic solution of gorgon euryale seed powder is gorgon euryale seed powder weight, all ultrasonic extraction three times, obtain bletilla striata extract respectively, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract.Agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract are all placed in 35 DEG C of temperature, and 10KPa vacuum under pressure concentrates, and the volumn concentration being concentrated into ethanol is 10%.
(2) by agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and the Gorgon fruit extract mixing after concentrated, obtain mixed liquor, mixed liquor is added in homogenizer, first homogeneous three times under 40MPa pressure, then homogeneous is once under 4.5MPa pressure.
(3) by the spraying dry under nitrogen protection of the mixed liquor after homogeneous, mixed-powder is obtained.
(4) by mixed-powder compressing tablet, enteric Maca tablet is obtained.Or mixed-powder is directly packed, obtain the agent of enteric pueraria root powder.Or by filling for mixed-powder one-tenth hard shell capsules.
Embodiment 5.
In the present embodiment, the production method of natural enteric agate coffee preparation is made up of the raw material of following parts by weight: pueraria root powder 45 parts, 5 parts, bletilla striata powder, konjaku flour 4.5 parts, yam flour 6 parts, kudzuvine root starch 9 parts, gorgon euryale seed powder 10 parts.This production method is made up of following steps successively.
(1) pueraria root powder use volumn concentration is the ethanolic solution extraction of 70%, for extracting 5 times that the weight of the ethanolic solution of pueraria root powder is pueraria root powder weight, ultrasonic extraction three times, obtains agate coffee extract.Bletilla striata powder, konjaku flour, yam flour, kudzuvine root starch and gorgon euryale seed powder all adopt volumn concentration be 50% ethanolic solution extract, for extracting 5 times that the weight of the ethanolic solution of bletilla striata powder is bletilla striata grain weight amount, for extracting 5 times that the weight of the ethanolic solution of konjaku flour is konjaku flour weight, for extracting 5 times that the weight of the ethanolic solution of yam flour is yam flour weight, for extracting 5 times that the weight of the ethanolic solution of kudzuvine root starch is kudzuvine root starch weight, for extracting 5 times that the weight of the ethanolic solution of gorgon euryale seed powder is gorgon euryale seed powder weight, all ultrasonic extraction three times, obtain bletilla striata extract respectively, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract.Agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract are all placed in 35 DEG C of temperature, and 10KPa vacuum under pressure concentrates, and the volumn concentration being concentrated into ethanol is 12%.
(2) by agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and the Gorgon fruit extract mixing after concentrated, obtain mixed liquor, mixed liquor is added in homogenizer, first homogeneous three times under 40MPa pressure, then homogeneous is once under 4.5MPa pressure.
(3) by the spraying dry under nitrogen protection of the mixed liquor after homogeneous, mixed-powder is obtained.
(4) by mixed-powder compressing tablet, enteric Maca tablet is obtained.Or mixed-powder is directly packed, obtain the agent of enteric pueraria root powder.Or by filling for mixed-powder one-tenth hard shell capsules.
Embodiment 6.
In the present embodiment, the production method of natural enteric agate coffee preparation is made up of the raw material of following parts by weight: pueraria root powder 30 parts, 6.5 parts, bletilla striata powder, konjaku flour 4 parts, yam flour 3 parts, kudzuvine root starch 12 parts, gorgon euryale seed powder 7 parts.This production method is made up of following steps successively.
(1) pueraria root powder use volumn concentration is the ethanolic solution extraction of 70%, for extracting 5 times that the weight of the ethanolic solution of pueraria root powder is pueraria root powder weight, ultrasonic extraction three times, obtains agate coffee extract.Bletilla striata powder, konjaku flour, yam flour, kudzuvine root starch and gorgon euryale seed powder all adopt volumn concentration be 50% ethanolic solution extract, for extracting 5 times that the weight of the ethanolic solution of bletilla striata powder is bletilla striata grain weight amount, for extracting 5 times that the weight of the ethanolic solution of konjaku flour is konjaku flour weight, for extracting 5 times that the weight of the ethanolic solution of yam flour is yam flour weight, for extracting 5 times that the weight of the ethanolic solution of kudzuvine root starch is kudzuvine root starch weight, for extracting 5 times that the weight of the ethanolic solution of gorgon euryale seed powder is gorgon euryale seed powder weight, all ultrasonic extraction three times, obtain bletilla striata extract respectively, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract.Agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract are all placed in 35 DEG C of temperature, and 10KPa vacuum under pressure concentrates, and the volumn concentration being concentrated into ethanol is 11%.
(2) by agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and the Gorgon fruit extract mixing after concentrated, obtain mixed liquor, mixed liquor is added in homogenizer, first homogeneous three times under 40MPa pressure, then homogeneous is once under 4.5MPa pressure.
(3) by the spraying dry under nitrogen protection of the mixed liquor after homogeneous, mixed-powder is obtained.
(4) by mixed-powder compressing tablet, enteric Maca tablet is obtained.Or mixed-powder is directly packed, obtain the agent of enteric pueraria root powder.Or by filling for mixed-powder one-tenth hard shell capsules.
Embodiment 7.
In the present embodiment, the production method of natural enteric agate coffee preparation is made up of the raw material of following parts by weight: pueraria root powder 50 parts, 6 parts, bletilla striata powder, konjaku flour 2 parts, yam flour 3.5 parts, kudzuvine root starch 11 parts, gorgon euryale seed powder 8 parts.This production method is made up of following steps successively.
(1) pueraria root powder use volumn concentration is the ethanolic solution extraction of 70%, for extracting 4 times that the weight of the ethanolic solution of pueraria root powder is pueraria root powder weight, ultrasonic extraction three times, obtains agate coffee extract.Bletilla striata powder, konjaku flour, yam flour, kudzuvine root starch and gorgon euryale seed powder all adopt volumn concentration be 50% ethanolic solution extract, for extracting 4 times that the weight of the ethanolic solution of bletilla striata powder is bletilla striata grain weight amount, for extracting 4 times that the weight of the ethanolic solution of konjaku flour is konjaku flour weight, for extracting 4 times that the weight of the ethanolic solution of yam flour is yam flour weight, for extracting 4 times that the weight of the ethanolic solution of kudzuvine root starch is kudzuvine root starch weight, for extracting 4 times that the weight of the ethanolic solution of gorgon euryale seed powder is gorgon euryale seed powder weight, all ultrasonic extraction three times, obtain bletilla striata extract respectively, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract.Agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract are all placed in 35 DEG C of temperature, and 10KPa vacuum under pressure concentrates, and the volumn concentration being concentrated into ethanol is 10.5%.
(2) by agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and the Gorgon fruit extract mixing after concentrated, obtain mixed liquor, mixed liquor is added in homogenizer, first homogeneous three times under 40MPa pressure, then homogeneous is once under 4.5MPa pressure.
(3) by the spraying dry under nitrogen protection of the mixed liquor after homogeneous, mixed-powder is obtained.
(4) by mixed-powder compressing tablet, enteric Maca tablet is obtained.Or mixed-powder is directly packed, obtain the agent of enteric pueraria root powder.Or by filling for mixed-powder one-tenth hard shell capsules.
Embodiment 8.
In the present embodiment, the production method of natural enteric agate coffee preparation is made up of the raw material of following parts by weight: pueraria root powder 55 parts, 5.5 parts, bletilla striata powder, konjaku flour 3.5 parts, yam flour 2 parts, kudzuvine root starch 8 parts, gorgon euryale seed powder 8.5 parts.This production method is made up of following steps successively.
(1) pueraria root powder use volumn concentration is the ethanolic solution extraction of 70%, for extracting 6 times that the weight of the ethanolic solution of pueraria root powder is pueraria root powder weight, ultrasonic extraction three times, obtains agate coffee extract.Bletilla striata powder, konjaku flour, yam flour, kudzuvine root starch and gorgon euryale seed powder all adopt volumn concentration be 50% ethanolic solution extract, for extracting 6 times that the weight of the ethanolic solution of bletilla striata powder is bletilla striata grain weight amount, for extracting 6 times that the weight of the ethanolic solution of konjaku flour is konjaku flour weight, for extracting 6 times that the weight of the ethanolic solution of yam flour is yam flour weight, for extracting 6 times that the weight of the ethanolic solution of kudzuvine root starch is kudzuvine root starch weight, for extracting 6 times that the weight of the ethanolic solution of gorgon euryale seed powder is gorgon euryale seed powder weight, all ultrasonic extraction three times, obtain bletilla striata extract respectively, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract.Agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract are all placed in 35 DEG C of temperature, and 10KPa vacuum under pressure concentrates, and the volumn concentration being concentrated into ethanol is 11.5%.
(2) by agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and the Gorgon fruit extract mixing after concentrated, obtain mixed liquor, mixed liquor is added in homogenizer, first homogeneous three times under 40MPa pressure, then homogeneous is once under 4.5MPa pressure.
(3) by the spraying dry under nitrogen protection of the mixed liquor after homogeneous, mixed-powder is obtained.
(4) by mixed-powder compressing tablet, enteric Maca tablet is obtained.Or mixed-powder is directly packed, obtain the agent of enteric pueraria root powder.Or by filling for mixed-powder one-tenth hard shell capsules.
Embodiment 9.
In the present embodiment, the production method of natural enteric agate coffee preparation is made up of the raw material of following parts by weight: pueraria root powder 70 parts, 7 parts, bletilla striata powder, konjaku flour 2.5 parts, yam flour 5 parts, kudzuvine root starch 10 parts, gorgon euryale seed powder 5 parts.This production method is made up of following steps successively.
(1) pueraria root powder use volumn concentration is the ethanolic solution extraction of 70%, for extracting 5 times that the weight of the ethanolic solution of pueraria root powder is pueraria root powder weight, ultrasonic extraction three times, obtains agate coffee extract.Bletilla striata powder, konjaku flour, yam flour, kudzuvine root starch and gorgon euryale seed powder all adopt volumn concentration be 50% ethanolic solution extract, for extracting 5 times that the weight of the ethanolic solution of bletilla striata powder is bletilla striata grain weight amount, for extracting 5 times that the weight of the ethanolic solution of konjaku flour is konjaku flour weight, for extracting 5 times that the weight of the ethanolic solution of yam flour is yam flour weight, for extracting 5 times that the weight of the ethanolic solution of kudzuvine root starch is kudzuvine root starch weight, for extracting 5 times that the weight of the ethanolic solution of gorgon euryale seed powder is gorgon euryale seed powder weight, all ultrasonic extraction three times, obtain bletilla striata extract respectively, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract.Agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract are all placed in 35 DEG C of temperature, and 10KPa vacuum under pressure concentrates, and the volumn concentration being concentrated into ethanol is 10%.
(2) by agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and the Gorgon fruit extract mixing after concentrated, obtain mixed liquor, mixed liquor is added in homogenizer, first homogeneous three times under 40MPa pressure, then homogeneous is once under 4.5MPa pressure.
(3) by the spraying dry under nitrogen protection of the mixed liquor after homogeneous, mixed-powder is obtained.
(4) by mixed-powder compressing tablet, enteric Maca tablet is obtained.Or mixed-powder is directly packed, obtain the agent of enteric pueraria root powder.Or by filling for mixed-powder one-tenth hard shell capsules.
Embodiment 10.
In the present embodiment, the production method of natural enteric agate coffee preparation is made up of the raw material of following parts by weight: pueraria root powder 60 parts, 7.5 parts, bletilla striata powder, konjaku flour 5 parts, yam flour 4.5 parts, kudzuvine root starch 6 parts, gorgon euryale seed powder 9 parts.This production method is made up of following steps successively.
(1) pueraria root powder use volumn concentration is the ethanolic solution extraction of 70%, for extracting 5 times that the weight of the ethanolic solution of pueraria root powder is pueraria root powder weight, ultrasonic extraction three times, obtains agate coffee extract.Bletilla striata powder, konjaku flour, yam flour, kudzuvine root starch and gorgon euryale seed powder all adopt volumn concentration be 50% ethanolic solution extract, for extracting 5 times that the weight of the ethanolic solution of bletilla striata powder is bletilla striata grain weight amount, for extracting 5 times that the weight of the ethanolic solution of konjaku flour is konjaku flour weight, for extracting 5 times that the weight of the ethanolic solution of yam flour is yam flour weight, for extracting 5 times that the weight of the ethanolic solution of kudzuvine root starch is kudzuvine root starch weight, for extracting 5 times that the weight of the ethanolic solution of gorgon euryale seed powder is gorgon euryale seed powder weight, all ultrasonic extraction three times, obtain bletilla striata extract respectively, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract.Agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract are all placed in 35 DEG C of temperature, and 10KPa vacuum under pressure concentrates, and the volumn concentration being concentrated into ethanol is 12%.
(2) by agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and the Gorgon fruit extract mixing after concentrated, obtain mixed liquor, mixed liquor is added in homogenizer, first homogeneous three times under 40MPa pressure, then homogeneous is once under 4.5MPa pressure.
(3) by the spraying dry under nitrogen protection of the mixed liquor after homogeneous, mixed-powder is obtained.
(4) by mixed-powder compressing tablet, enteric Maca tablet is obtained.Or mixed-powder is directly packed, obtain the agent of enteric pueraria root powder.Or by filling for mixed-powder one-tenth hard shell capsules.
Although the present invention with embodiment openly as above; but it is also not used to limit protection scope of the present invention; any technical staff being familiar with this technology, not departing from the change and retouching done in the spirit and scope of the present invention, all should belong to protection scope of the present invention.
Claims (7)
1. a natural enteric agate coffee preparation, is characterized in that: said preparation is made up of the raw material of following parts by weight: pueraria root powder 30 ~ 70 parts, 5 ~ 8 parts, bletilla striata powder, konjaku flour 2 ~ 5 parts, yam flour 2 ~ 6 parts, kudzuvine root starch 6 ~ 12 parts, gorgon euryale seed powder 5 ~ 10 parts.
2. natural enteric agate coffee preparation according to claim 1, it is characterized in that: described pueraria root powder adopt volumn concentration be 70% ethanolic solution extract, described bletilla striata powder, konjaku flour, yam flour, kudzuvine root starch and gorgon euryale seed powder all adopt volumn concentration be 50% ethanolic solution extract.
3. a production method for natural enteric agate coffee preparation, is characterized in that: described production method is made up of the raw material of following parts by weight: pueraria root powder 30 ~ 70 parts, 5 ~ 8 parts, bletilla striata powder, konjaku flour 2 ~ 5 parts, yam flour 2 ~ 6 parts, kudzuvine root starch 6 ~ 12 parts, gorgon euryale seed powder 5 ~ 10 parts; This production method is made up of following steps successively:
(1) pueraria root powder use volumn concentration is the ethanolic solution extraction of 70%, obtains agate coffee extract; Bletilla striata powder, konjaku flour, yam flour, kudzuvine root starch and gorgon euryale seed powder all adopt volumn concentration be 50% ethanolic solution extract, obtain bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract respectively; Agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract are all in 35 DEG C of temperature, and 10KPa vacuum under pressure concentrates, and the volumn concentration being concentrated into ethanol is 10% ~ 12%;
(2) by agate coffee extract, bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and the Gorgon fruit extract mixing after concentrated, obtain mixed liquor, mixed liquor is added in homogenizer, first homogeneous three times under 40MPa pressure, then homogeneous is once under 4.5MPa pressure;
(3) by the spraying dry under nitrogen protection of the mixed liquor after homogeneous, mixed-powder is obtained;
(4) by mixed-powder compressing tablet, enteric Maca tablet is obtained; Or mixed-powder is directly packed, obtain the agent of enteric pueraria root powder; Or by filling for mixed-powder one-tenth hard shell capsules.
4. the production method of natural enteric agate coffee preparation according to claim 3, it is characterized in that: for extracting 4-6 times that the weight of the ethanolic solution of pueraria root powder is pueraria root powder weight, for extracting 4-6 times that the weight of the ethanolic solution of bletilla striata powder is bletilla striata grain weight amount, for extracting 4-6 times that the weight of the ethanolic solution of konjaku flour is konjaku flour weight, for extracting 4-6 times that the weight of the ethanolic solution of yam flour is yam flour weight, for extracting 4-6 times that the weight of the ethanolic solution of kudzuvine root starch is kudzuvine root starch weight, for extracting 4-6 times that the weight of the ethanolic solution of gorgon euryale seed powder is gorgon euryale seed powder weight.
5. the production method of natural enteric agate coffee preparation according to claim 3, is characterized in that: in described step (1), pueraria root powder use volumn concentration be 70% the ultrasonic extraction of ethanolic solution three times, obtain agate coffee extract.
6. the production method of natural enteric agate coffee preparation according to claim 3, it is characterized in that: in described step (1), bletilla striata powder, konjaku flour, yam flour, kudzuvine root starch and gorgon euryale seed powder all adopt volumn concentration be 50% the ultrasonic extraction of ethanolic solution three times, obtain bletilla striata extract, konjaku extract, Chinese yam extract, root of kudzu vine extract and Gorgon fruit extract respectively.
7. the production method of natural enteric agate coffee preparation according to claim 4, it is characterized in that: for extracting 5 times that the weight of the ethanolic solution of pueraria root powder is pueraria root powder weight, for extracting 5 times that the weight of the ethanolic solution of bletilla striata powder is bletilla striata grain weight amount, for extracting 5 times that the weight of the ethanolic solution of konjaku flour is konjaku flour weight, for extracting 5 times that the weight of the ethanolic solution of yam flour is yam flour weight, for extracting 5 times that the weight of the ethanolic solution of kudzuvine root starch is kudzuvine root starch weight, for extracting 5 times that the weight of the ethanolic solution of gorgon euryale seed powder is gorgon euryale seed powder weight.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102757880A (en) * | 2012-07-25 | 2012-10-31 | 北京中科健宇生物科技有限公司 | Maca health-care wine and preparation method thereof |
| CN102824545A (en) * | 2012-08-22 | 2012-12-19 | 厦门鹰君药业有限公司 | Blood sugar-reduction traditional Chinese medicine composition |
| CN103181951A (en) * | 2012-10-29 | 2013-07-03 | 赵言林 | Application of pseudo-ginseng and maca composition to treatment of dizziness, headache and hand-foot numbness |
| CN103584098A (en) * | 2013-11-16 | 2014-02-19 | 丽江玛咖生物科技有限公司 | Maca almond tablet and preparation method thereof |
| KR20140103572A (en) * | 2013-02-18 | 2014-08-27 | (주)엠피위즈 | A functional liquid composition comprising arginine, maca powder extract, citric acid and polydextrose as main ingredients |
-
2014
- 2014-10-10 CN CN201410530466.2A patent/CN104286872B/en not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102757880A (en) * | 2012-07-25 | 2012-10-31 | 北京中科健宇生物科技有限公司 | Maca health-care wine and preparation method thereof |
| CN102824545A (en) * | 2012-08-22 | 2012-12-19 | 厦门鹰君药业有限公司 | Blood sugar-reduction traditional Chinese medicine composition |
| CN103181951A (en) * | 2012-10-29 | 2013-07-03 | 赵言林 | Application of pseudo-ginseng and maca composition to treatment of dizziness, headache and hand-foot numbness |
| KR20140103572A (en) * | 2013-02-18 | 2014-08-27 | (주)엠피위즈 | A functional liquid composition comprising arginine, maca powder extract, citric acid and polydextrose as main ingredients |
| CN103584098A (en) * | 2013-11-16 | 2014-02-19 | 丽江玛咖生物科技有限公司 | Maca almond tablet and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 黄族和: "褐藻胶肠溶片剂研制报告", 《福建水产》, vol. 3, no. 10, 31 December 1998 (1998-12-31), pages 35 - 41 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104642966A (en) * | 2015-03-17 | 2015-05-27 | 武俐宏 | Using and preparation methods of konjak vitamin powder |
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