CN104284677A - 用于肿瘤诊断和治疗的组合物和方法 - Google Patents

用于肿瘤诊断和治疗的组合物和方法 Download PDF

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Publication number
CN104284677A
CN104284677A CN201380025032.0A CN201380025032A CN104284677A CN 104284677 A CN104284677 A CN 104284677A CN 201380025032 A CN201380025032 A CN 201380025032A CN 104284677 A CN104284677 A CN 104284677A
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antibody
seq
sequence
polypeptide
cdr
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CN201380025032.0A
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Chinese (zh)
Inventor
S·贝克特
M·黑曾
J-A·S·洪戈
J·R·朱努图拉
I·霍泽尔
Y·尚
S-F·于
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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CN201380025032.0A 2012-05-14 2013-03-14 用于肿瘤诊断和治疗的组合物和方法 Pending CN104284677A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261646803P 2012-05-14 2012-05-14
US61/646,803 2012-05-14
US201361776603P 2013-03-11 2013-03-11
US61/776,603 2013-03-11
PCT/US2013/031547 WO2013172961A1 (en) 2012-05-14 2013-03-14 Compositions and methods for the diagnosis and treatment of tumor

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CN104284677A true CN104284677A (zh) 2015-01-14

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US (1) US9580514B2 (https=)
EP (1) EP2849789A4 (https=)
JP (1) JP2015523852A (https=)
KR (1) KR20150013277A (https=)
CN (1) CN104284677A (https=)
BR (1) BR112014027905A2 (https=)
CA (1) CA2871116A1 (https=)
HK (1) HK1201045A1 (https=)
MX (1) MX2014013806A (https=)
RU (1) RU2014145633A (https=)
WO (1) WO2013172961A1 (https=)

Cited By (2)

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CN109709340A (zh) * 2018-12-29 2019-05-03 江苏众红生物工程创药研究院有限公司 人中性粒细胞明胶酶相关脂质运载蛋白定量检测卡及其临床应用
CN113332448A (zh) * 2017-03-17 2021-09-03 浙江孚诺医药股份有限公司 肿瘤靶向多肽、制备方法及其应用

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UA118950C2 (uk) 2011-04-22 2019-04-10 Аптево Рісьорч Енд Девелопмент Ллс Поліпептид, який зв'язує специфічний мембранний антиген простати та комплекс т-клітинного рецептора
PL3489261T3 (pl) 2012-08-24 2021-08-16 The Regents Of The University Of California Przeciwciała i szczepionki do stosowania w leczeniu nowotworów z ekspresją ROR1 i w hamowaniu przerzutu
EP3352760B1 (en) 2015-09-21 2026-03-11 Aptevo Research and Development LLC Cd3 binding polypeptides
WO2017152088A1 (en) 2016-03-04 2017-09-08 JN Biosciences, LLC Antibodies to tigit
IL299099B2 (en) 2016-06-27 2025-07-01 Univ California Cancer treatment combinations
US11690919B2 (en) * 2017-01-17 2023-07-04 The Texas A&M University System Endolysosomal targeting conjugates for improved delivery of cargo molecules to the endolysosomal compartment of target cells
BR112022024221A2 (pt) 2020-06-02 2022-12-20 Arcus Biosciences Inc Anticorpos para tigit
CN112457406B (zh) * 2020-11-27 2022-05-31 中国科学院上海药物研究所 一种抗mmae的单克隆抗体、其编码序列及应用

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