CN104274512A - Traditional Chinese medicine for treatment of chronic atrophic gastritis - Google Patents
Traditional Chinese medicine for treatment of chronic atrophic gastritis Download PDFInfo
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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Abstract
The invention belongs to the technical field of traditional Chinese medicine preparation, and particularly relates to a traditional Chinese medicine for the treatment of chronic atrophic gastritis. The traditional Chinese medicine comprises the following components in parts: 25-30 parts of radix astragali, 26-30 parts of radix codonopsis, 8-12 parts of bighead atractylodes rhizome, 12-16 parts of edicated leaven, 8-10 parts of angelica sinensis, 25-30 parts of rhizome of chuanxiong, and 6-8 parts of honey-fried licorice roots. The traditional Chinese medicine prepared according to the invention is simple in formula, low in cost and high in curative effect, has no toxic or side effect, and can treat chronic atrophic gastritis safely and effectively.
Description
Technical field
The invention belongs to Chinese drug preparation technique field, particularly relate to a kind of Chinese medicine for the treatment of chronic atrophic gastritis.
Background technology
Now, due to the increasing gradually of life stress and operating pressure, the bad habit that more people has caught smoking, has been addicted to drink, zest rubbish " quick food " is also more and more favored, but these dietary habit make the health of people be in sub-health state just, especially to stimulation and the infringement of gastric mucosa.Along with popularizing of gastroscope, the recall rate of chronic atrophic gastritis obviously increases.
Chronic atrophic gastritis (Chronic atrophic gastritis) is one of common disease of stomach, refer to that the chronic gastritis of atrophic change has occurred gastric mucosa, the intrinsic body of gland atrophy of the mucosa caused after mucosa surface suffers damage repeatedly, even disappear, the glutinous common pathological change thickened of muscle layer.This disease is one of digestive system commonly encountered diseases, frequently-occurring disease, in chronic gastritis, account for 10% ~ 30%.Pathology is main change with the intrinsic gland atrophy of gastric mucosa, can with intestinal epithelial metaplasia, inflammatory reaction and dysplasia.The indigestion symptoms such as clinical manifestation is Abdeminal pain, belch, stomach poor appetite move back.Although the application of Western medicine can make the symptom of patient improve, be not enough to make the gastric mucosa of atrophy to be repaired.
Summary of the invention
The present invention is directed to the deficiency that above-mentioned prior art exists, a kind of evident in efficacy, cheap, Chinese medicine for the treatment of chronic atrophic gastritis of having no side effect is provided.
The technical scheme that the present invention solves the problems of the technologies described above is as follows: a kind of Chinese medicine for the treatment of chronic atrophic gastritis, is prepared from by the medical material of following weight proportion: Radix Astragali 25-30 part, Radix Codonopsis 26-30 part, Rhizoma Atractylodis Macrocephalae 8-12 part, Massa Medicata Fermentata 12-16 part, Radix Angelicae Sinensis 8-10 part, Rhizoma Chuanxiong 25-30 part and Radix Glycyrrhizae Preparata 6-8 part.
Treat a Chinese medicine for chronic atrophic gastritis, be preferably prepared from by the medical material of following weight proportion: the Radix Astragali 30 parts, Radix Codonopsis 30 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Massa Medicata Fermentata 15 parts, Radix Angelicae Sinensis 10 parts, Rhizoma Chuanxiong 30 parts and Radix Glycyrrhizae Preparata 6 parts.
Pharmacology involved by Chinese medicine of the present invention is as follows:
The Radix Astragali: invigorating the spleen and replenishing QI, yang invigorating, consolidating superficial resistance, poison holding sore, inducing diuresis to remove edema.Containing dimethoxy isoflavone, kumatakenin, choline, betanin, polysaccharide, glucuronic acid and micro-folic acid etc.Energy enhancing human body immunity function, promotes organism metabolism, for deficiency of spleen-QI and stomach-QI.
Radix Codonopsis: QI invigorating strengthening the spleen stomach, containing Saponin, inulin, Alkaloid etc.Spleen and stomach function can be strengthened and QI invigorating.
The Rhizoma Atractylodis Macrocephalae: the spleen strengthening and damp drying, diuretic, hidroschesis, antiabortive.Containing volatile oil.Main body of oil is Rhizoma Atractylodis ketone and atractylodes lactone A, B.The another retinoids containing denier, can adjust gastrointestinal motility function, reduces gastric acidity, reduces gastric acid and pepsic output.
Massa Medicata Fermentata: invigorating the spleen and regulating the stomach, promoting digestion and removing stagnation.Containing compositions such as yeast, amylase, ergosterol, volatile oil, fat, protein and vitamin Bs, thus have fabulous to help digestion, intestinal stasis relieving, stomach function regulating preventing or arresting vomiting, the effect that increases appetite, promote metabolism.Can be used for disease such as treatment chronic gastritis, atrophic gastritis etc. clinically.
Radix Angelicae Sinensis: enrich blood, blood circulation promoting and blood stasis dispelling, regulating menstruation, loosening bowel to relieve constipation.Containing volatile oil, organic acid, saccharide, vitamin, aminoacid etc. in Radix Angelicae Sinensis.Suffer from abdominal pain for deficient cold type.Also have antiinflammatory, antibacterial action.Special efficacy is had to the atrophic gastritis that helicobacter pylori causes.
Rhizoma Chuanxiong: blood circulation promoting and blood stasis dispelling, wind-expelling pain-stopping.Main containing the aldehydes matter such as alkaloid, ferulic acid, again containing volatile oil, lactone and vitamin A, folic acid etc.The breast side of body of qi depression to blood stasis, all pains of suffering from abdominal pain can be treated.
Radix Glycyrrhizae Preparata: invigorating the spleen and replenishing QI, relieving spasm to stop pain.Main containing glycyrrhizin and multiple flavone, can the not enough and gas in benefit of tonifying the spleen and stomach.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects the out-patient of 100 routine chronic atrophic gastritis altogether-2012 years in January, 2010 between JIUYUE, age 19-80 year, course of disease 0.5-5.Be divided at random: treatment group 60 example, blank group 40 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2, test method
The honeyed pill that the oral the present invention of 2.1 treatment group obtains according to specific embodiment 1, sooner or later respectively once.3 months courses for the treatment of.
2.2 blank group oral placebo capsules, sooner or later respectively once.3 months courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and lab testing is normal.
Take a turn for the better: clinical symptom relief, the state of an illness is controlled, lab testing improvement or normal.
Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) |
| Treatment group | 60 | 6(10％) | 50(83.3％) | 4(6.7％) | 93.3％ |
| Blank group | 40 | 0 | 2(5％) | 38(95％) | 5％ |
4, medical case history is enumerated (being protection patients ' privacy, temporarily with surname representative):
4.1 Zhao, man, 76 years old, Zhaoyuan, shandong people, in February, 2010 carried out my institute's row gastroscopy because of abdominal discomfort, and imperfection intestinal epithelial metaplasia that moderate atrophic gastritis accompanied is slight, takes this Chinese medicine 3 months continuously, and the histological examination of row gastroscopic biopsy is slight intestinal epithelial metaplasia.
4.2 Wang, man, 19 years old, Zhaoyuan, shandong people, in December, 2010 carried out my institute's row gastroscopy because of abdominal pain and distension, and imperfection intestinal epithelial metaplasia that moderate atrophic gastritis accompanied is slight, takes this Chinese medicine 3 months continuously, and the histological examination of row gastroscopic biopsy is slight intestinal epithelial metaplasia.
4.3 grandsons, female, 71 years old, Zhaoyuan, shandong people, for many years atrophic gastritis, in March, 2011, I checked by institute's gastroscope, the intestinal epithelial metaplasia of severe atrophic gastritis accompanied severe imperfection, takes this Chinese medicine 6 months continuously, and the histological examination of row gastroscopic biopsy is the slight intestinal epithelial metaplasia of moderate atrophic gastritis accompanied.
4.4 Yans, female, 79 years old, Zhaoyuan, shandong people, in June, 2011 carried out my institute's row gastroscopy because of abdominal discomfort, and imperfection intestinal epithelial metaplasia that moderate atrophic gastritis accompanied is slight, takes this Chinese medicine 3 months continuously, and the histological examination of row gastroscopic biopsy is slight atrophic gastritis.
4.5 Zhangs, female, 73 years old, Laizhou, Shandong people, in November, 2011 carried out my institute's row gastroscopy because of abdominal pain and distension, and imperfection intestinal epithelial metaplasia that moderate atrophic gastritis accompanied is slight, takes this Chinese medicine 3 months continuously, and the histological examination of row gastroscopic biopsy is slight intestinal epithelial metaplasia.
4.6 Wang, female, 38 years old, Laizhou, Shandong people, in February, 2012, Physical Examination carried out my institute's row gastroscopy, and imperfection intestinal epithelial metaplasia that slight atrophic gastritis accompanied is slight, takes this Chinese medicine 3 months continuously, and the histological examination of row gastroscopic biopsy is the slight chronic inflammation of gastric mucosa.
4.7 clothing, man, 41 years old, people from Qixia, Shandong, in June, 2012, Physical Examination carried out my institute's row gastroscopy, and imperfection intestinal epithelial metaplasia that slight atrophic gastritis accompanied is slight, takes this Chinese medicine 3 months continuously, and the histological examination of row gastroscopic biopsy is the slight chronic inflammation of gastric mucosa.
In 4.8 summers, man, 43 years old, people from Longkou, in JIUYUE, 2012 carried out my institute's row gastroscopy because of abdominal pain and distension, and imperfection intestinal epithelial metaplasia that moderate atrophic gastritis accompanied is slight, takes this Chinese medicine 3 months continuously, and the histological examination of row gastroscopic biopsy is slight intestinal epithelial metaplasia.
Visible, the medicament composing prescription that the present invention obtains is simple, and cheap, curative effect is high, has no side effect, can safe and effective treatment chronic atrophic gastritis, and treated effect reaches 93.3%.
Detailed description of the invention
Be described principle of the present invention and feature below in conjunction with example, example, only for explaining the present invention, is not intended to limit scope of the present invention.
Embodiment 1
Treat a Chinese medicine for chronic atrophic gastritis, be prepared from by the medical material of following weight proportion: Radix Astragali 30g, Radix Codonopsis 30g, Rhizoma Atractylodis Macrocephalae 10g, Massa Medicata Fermentata 15g, Radix Angelicae Sinensis 10g, Rhizoma Chuanxiong 30g and Radix Glycyrrhizae Preparata 6g.
Its preparation method is:
(1) take the mixing of above-mentioned raw material, put into drying baker after cleaning up and dry;
(2) the oven dry medical material of step (1) is ground to form graininess, with 100 object sieves, ground raw material is sieved, the little pharmaceutical filtration of granule out, for future use, the grinding of carrying out again that granule is large is sieved, and finally reaches the object of sieving;
(3) 3kg Mel is put into the refining of pot low baking temperature, solidifying as maltosemalt sugar shape, that stirs does not make Jiao;
(4) finally the refined honey of step (3) is mixed with the medicamental pulverata of step (2) and rubs by evenly, place 0.5h, again rub by, make the honeyed pill of 6g size, each serving with a honeyed pill.
Be used for the treatment of chronic atrophic gastritis, oral, every bu is taken for twice sooner or later.
Embodiment 2
Treat a Chinese medicine for chronic atrophic gastritis, be prepared from by the medical material of following weight proportion: Radix Astragali 25g, Radix Codonopsis 26g, Rhizoma Atractylodis Macrocephalae 12g, Massa Medicata Fermentata 16g, Radix Angelicae Sinensis 8g, Rhizoma Chuanxiong 25g and Radix Glycyrrhizae Preparata 8g.
Its preparation method is:
(1) take the mixing of above-mentioned raw material, put into drying baker after cleaning up and dry;
(2) the oven dry medical material of step (1) is ground to form graininess, with 100 object sieves, ground raw material is sieved, the little pharmaceutical filtration of granule out, for future use, the grinding of carrying out again that granule is large is sieved, and finally reaches the object of sieving;
(3) packed in units of 6g by the medicament powder that step (2) obtains, each bag is a dose.
Be used for the treatment of chronic atrophic gastritis, hot water electuary is oral, and every bu is taken for twice sooner or later.
Embodiment 3
Treat a Chinese medicine for chronic atrophic gastritis, be prepared from by the medical material of following weight proportion: Radix Astragali 28g, Radix Codonopsis 28g, Rhizoma Atractylodis Macrocephalae 8g, Massa Medicata Fermentata 12g, Radix Angelicae Sinensis 9g, Rhizoma Chuanxiong 28g and Radix Glycyrrhizae Preparata 7g.
Its preparation method is:
(1) take the mixing of above-mentioned raw material, clean up;
(2) medical material of step (1) is put into medicinal cupping, boil after soaking 0.5h with 4kg clear water, then slow fire infusion is ceased fire to medicine juice residue 1kg;
(3) elimination medicinal residues, obtain medicinal liquid 1500ml, staticly settle 24h, and leaching supernatant concentration is to 500ml, and the sterilizing of every 100ml subpackage, obtains injection, and every 100ml is injection shot.
Be used for the treatment of chronic atrophic gastritis, injection, every bu sooner or later respectively once.
Embodiment 4
Treat a Chinese medicine for chronic atrophic gastritis, be prepared from by the medical material of following weight proportion: Radix Astragali 30g, Radix Codonopsis 30g, Rhizoma Atractylodis Macrocephalae 10g, Massa Medicata Fermentata 15g, Radix Angelicae Sinensis 10g, Rhizoma Chuanxiong 30g and Radix Glycyrrhizae Preparata 6g.
Its preparation method is:
(1) take the mixing of above-mentioned raw material, put into drying baker after cleaning up and dry;
(2) the oven dry medical material of step (1) is ground to form graininess, with 100 object sieves, ground raw material is sieved, the little pharmaceutical filtration of granule out, for future use, the grinding of carrying out again that granule is large is sieved, and finally reaches the object of sieving;
(3) the medicament powder that step (2) obtains is incapsulated shell in units of 0.6g, make capsule, each capsules is a dose.
Be used for the treatment of chronic atrophic gastritis, oral, every bu is taken for twice sooner or later.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (2)
1. treat a Chinese medicine for chronic atrophic gastritis, it is characterized in that being prepared from by the medical material of following weight proportion: Radix Astragali 25-30 part, Radix Codonopsis 26-30 part, Rhizoma Atractylodis Macrocephalae 8-12 part, Massa Medicata Fermentata 12-16 part, Radix Angelicae Sinensis 8-10 part, Rhizoma Chuanxiong 25-30 part and Radix Glycyrrhizae Preparata 6-8 part.
2. a kind of Chinese medicine for the treatment of chronic atrophic gastritis according to claim 1, is characterized in that being prepared from by the medical material of following weight proportion: the Radix Astragali 30 parts, Radix Codonopsis 30 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Massa Medicata Fermentata 15 parts, Radix Angelicae Sinensis 10 parts, Rhizoma Chuanxiong 30 parts and Radix Glycyrrhizae Preparata 6 parts.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109731064A (en) * | 2018-11-29 | 2019-05-10 | 王丽 | A kind of Chinese materia medica preparation for alleviating belly flatulence |
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| CN102641454A (en) * | 2012-05-22 | 2012-08-22 | 江苏省中医药研究院 | Traditional Chinese medicine composition for treating chronic atrophic gastritis |
| CN102716436A (en) * | 2012-05-16 | 2012-10-10 | 王桂琴 | Capsule for treating atrophic gastritis |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102716436A (en) * | 2012-05-16 | 2012-10-10 | 王桂琴 | Capsule for treating atrophic gastritis |
| CN102641454A (en) * | 2012-05-22 | 2012-08-22 | 江苏省中医药研究院 | Traditional Chinese medicine composition for treating chronic atrophic gastritis |
Non-Patent Citations (2)
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109731064A (en) * | 2018-11-29 | 2019-05-10 | 王丽 | A kind of Chinese materia medica preparation for alleviating belly flatulence |
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Application publication date: 20150114 |