CN104258210A - Chinese herbal medicine composition for treating psoriasis and preparation method thereof - Google Patents

Chinese herbal medicine composition for treating psoriasis and preparation method thereof Download PDF

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Publication number
CN104258210A
CN104258210A CN201410494494.3A CN201410494494A CN104258210A CN 104258210 A CN104258210 A CN 104258210A CN 201410494494 A CN201410494494 A CN 201410494494A CN 104258210 A CN104258210 A CN 104258210A
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radix
medicine composition
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chinese herbal
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何天鹏
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486—Millettia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634—Forsythia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/808—Scrophularia (figwort)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968—Ophiopogon (Lilyturf)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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Abstract

The invention discloses a Chinese herbal medicine composition for treating psoriasis and a preparation method thereof. The Chinese herbal medicine composition comprises the following raw material medicines in parts by weight: 6-11 parts of root of rehmannia, 9-15 parts of red paeony root, 5-12 parts of coptis chinensis, 10-16 parts of radix ophiopogonis, 3-7 parts of honeysuckle flower, 4-13 parts of fructus forsythiae, 15-20 parts of angelica sinensis, 12-17 parts of rhizoma smilacis glabrae, 7-15 parts of radix scrophulariae, 14-21 parts of Caulis Spatholobi and 5-10 parts of fleece-flower root. The Chinese herbal medicine composition disclosed by the invention has the beneficial effects that the selected materials are natural traditional Chinese medicine materials, the Chinese herbal medicine composition does not have any toxic or side effect, is fast in effectiveness of treatment of psoriasis, readily available in drug source and low in price, and psoriasis is difficult to reoccur.

Description

One treats psoriasic herbal composite and preparation method thereof
 
Technical field
The invention belongs to technical field of Chinese medicine, be specifically related to one and treat psoriasic herbal composite and preparation method thereof.
Background technology
Psoriasis is commonly called as psoriasis, it is a kind of common chronic recurrent inflammatory dermatoses, characteristic lesions is that red papules or speckle are covered with multilamellar silvery white squama, be apt to occur in extremity and stretch side, scalp and back, serious skin lesion can general whole body, and can occur high heat, pustule, the change of erythroderma sample and whole body size arthropathy.The course of disease is longer, has easy tendency of recurrence, and some cases almost cannot be cured all one's life.The morbidity of this disease, based on person between twenty and fifty, affects larger on the healthy of patient and mental status.Clinical manifestation is with erythema, and squama is main, and whole body all can be fallen ill, and with scalp, it is comparatively common that extremity stretch side, how to increase the weight of in the winter time.According to the feature of skin lesion, psoriasis is divided into Four types clinically, i.e. homeliness type, arthropathica, erythrodermic and pustule type.Psoriatic can have renal damage, also can with liver, eye, gastrointestinal tract, the organ diseases such as cardiovascular.
At present mainly the agents alleviate state of an illness such as Donisolone, 0.1% ~ 2% anthralin Ointment, tar preparation are passed through for treatment psoriasis, the sequelas such as irritant dermatitis may be caused, also need the convalescent period of large section time afterwards, but also likely recur, can not fully recover.So do not have effective fast treating psoriasis now and the herbal composite had no side effect without recurrence.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, providing a kind of rapid, effective treatment psoriasis and without recurring herbal composite of having no side effect and preparation method thereof.
Technical scheme of the present invention is: one treats psoriasic herbal composite, be made up of following weight portion herbal raw material: 6 ~ 11 parts, the Radix Rehmanniae, Radix Paeoniae Rubra 9 ~ 15 parts, Rhizoma Coptidis 5 ~ 12 parts, Radix Ophiopogonis 10 ~ 16 parts, Flos Lonicerae 3 ~ 7 parts, Fructus Forsythiae 4 ~ 13 parts, Radix Angelicae Sinensis 15 ~ 20 parts, Rhizoma Smilacis Glabrae 12 ~ 17 parts, Radix Scrophulariae 7 ~ 15 parts, Caulis Spatholobi 14 ~ 21 parts, the Radix Polygoni Multiflori 5 ~ 10 parts.
Preferably, one treats psoriasic herbal composite, is made up of following weight portion herbal raw material: 8 parts, the Radix Rehmanniae, Radix Paeoniae Rubra 11 parts, Rhizoma Coptidis 5 parts, Radix Ophiopogonis 10 parts, Flos Lonicerae 4 parts, Fructus Forsythiae 5 parts, Radix Angelicae Sinensis 16 parts, Rhizoma Smilacis Glabrae 12 parts, Radix Scrophulariae 7 parts, Caulis Spatholobi 15 parts, the Radix Polygoni Multiflori 7 parts.
Preferably, one treats psoriasic herbal composite, is made up of following weight portion herbal raw material: 10 parts, the Radix Rehmanniae, Radix Paeoniae Rubra 9 parts, Rhizoma Coptidis 8 parts, Radix Ophiopogonis 13 parts, Flos Lonicerae 6 parts, Fructus Forsythiae 10 parts, Radix Angelicae Sinensis 18 parts, Rhizoma Smilacis Glabrae 15 parts, Radix Scrophulariae 11 parts, Caulis Spatholobi 17 parts, the Radix Polygoni Multiflori 9 parts.
This ingredient pharmacology is as follows:
The Radix Rehmanniae: nature and flavor: sweet, cold.Gui Jing: GUIXIN, liver, kidney channel.Effect: Radix Rehmanniae clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis.
Radix Paeoniae Rubra: nature and flavor: bitter, is slightly cold.Gui Jing: return Liver Channel.Effect: clearing away heat and cooling blood, eliminating stasis to stop pain.
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation.
Radix Ophiopogonis: nature and flavor: sweet, micro-hardship, is slightly cold.Gui Jing: GUIXIN, lung, stomach warp.Effect: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.Cure mainly: for dryness of the lung dry cough.Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.
Flos Lonicerae: nature and flavor: sweet, cold.Gui Jing: return lung, the heart, stomach warp.Effect: heat-clearing and toxic substances removing. wind-heat dissipating.
Fructus Forsythiae: nature and flavor: bitter, is slightly cold.Gui Jing: return lung, the heart, small intestine meridian.Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.
Radix Angelicae Sinensis: nature and flavor: sweet, acrid, warm.Gui Jing: return liver, the heart, spleen channel.Effect: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
Rhizoma Smilacis Glabrae: nature and flavor: sweet light is flat.Gui Jing: Liver Channel; Stomach warp; Spleen channel.Function: removing toxic substances, dehumidifying, sharp joint.
Radix Scrophulariae: nature and flavor: sweet, bitter, salty, is slightly cold.Gui Jing: return lung, stomach, kidney channel.Effect: removing heat from blood YIN nourishing, eliminating fire and detoxication.
Caulis Spatholobi: nature and flavor: bitter, sweet, temperature.Gui Jing: return liver, kidney channel.Effect: enrich blood, invigorates blood circulation, dredging collateral.
The Radix Polygoni Multiflori: nature and flavor: bitter, sweet, puckery. temperature.Gui Jing: return liver, the heart, kidney channel.Effect: removing toxic substances, disappears de-, loosening bowel to relieve constipation.
The preparation method of the psoriasic herbal composite for the treatment of of the present invention, is take raw material by above-mentioned formula, inserts in marmite and add cold water soak 20 ~ 30 minutes, add a cover decoction.First decoct with high heat, then use slow fire boiling.Slow fire boiling is after 10 ~ 15 minutes, and leaching is medicinal liquid for the first time; Heating water is appropriate, decocts according to upper method, gets second time medicinal liquid.By twice liquid medicine mixing and get final product.
The invention has the beneficial effects as follows: selected materials is all natural Chinese medicine material, without any side effects; To treatment psoriasis instant effect, not easily recur, medicine source is easy to get, cheap.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment, but protection domain is not limited thereto.
Embodiment 1:
Proportioning: 8 parts, the Radix Rehmanniae, Radix Paeoniae Rubra 11 parts, Rhizoma Coptidis 5 parts, Radix Ophiopogonis 10 parts, Flos Lonicerae 4 parts, Fructus Forsythiae 5 parts, Radix Angelicae Sinensis 16 parts, Rhizoma Smilacis Glabrae 12 parts, Radix Scrophulariae 7 parts, Caulis Spatholobi 15 parts, the Radix Polygoni Multiflori 7 parts.
Embodiment 2:
Proportioning: 10 parts, the Radix Rehmanniae, Radix Paeoniae Rubra 9 parts, Rhizoma Coptidis 8 parts, Radix Ophiopogonis 13 parts, Flos Lonicerae 6 parts, Fructus Forsythiae 10 parts, Radix Angelicae Sinensis 18 parts, Rhizoma Smilacis Glabrae 15 parts, Radix Scrophulariae 11 parts, Caulis Spatholobi 17 parts, the Radix Polygoni Multiflori 9 parts.
The preparation method of the psoriasic herbal composite of above-mentioned treatment: take raw material by above-mentioned formula, inserts in marmite and adds cold water soak 20 ~ 30 minutes, add a cover decoction.First decoct with high heat, then use slow fire boiling.Slow fire boiling is after 10 ~ 15 minutes, and leaching is medicinal liquid for the first time; Heating water is appropriate, decocts according to upper method, gets second time medicinal liquid.By twice liquid medicine mixing and get final product.
The instructions of taking of the psoriasic herbal composite of above-mentioned treatment: every day 1 dose, every day takes for twice.
Model case:
Case 1: Zhang, the age: 25 years old; Sex: male.There is the erythema that boundary is clear, shape size differs, have inflammatory blush, surface coverage multilamellar silvery white squama around.Squama is easy to scrape de-, and light red shinny semitransparent thin film after scraping, scratches the visible little petechia of thin film.Treatment is passed through: after taking two courses for the treatment of of Chinese medicine composition of proportioning in embodiment 1, symptom alleviates, the minimizing of silver bits; To continue to take after a course for the treatment of symptom completely without, follow up a case by regular visits to 1 year, symptom has no recurrence.
Case 2: together certain, the age: 15 years old; Sex: women.Health red papules or speckle are covered with multilamellar silvery white squama, send out and stretch side, scalp and back in extremity, occur high heat, pustule, erythroderma sample.Treat through: after taking 3 courses for the treatment of of Chinese medicine composition of proportioning in the embodiment of the present invention 2, symptom alleviates, and after continuing to take 2 courses for the treatment of, transference cure, follow up a case by regular visits to 1 year, symptom has no recurrence.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (4)

1. treat a psoriasic herbal composite, it is characterized in that, get following bulk drugs, be weight portion: 6 ~ 11 parts, the Radix Rehmanniae, Radix Paeoniae Rubra 9 ~ 15 parts, Rhizoma Coptidis 5 ~ 12 parts, Radix Ophiopogonis 10 ~ 16 parts, Flos Lonicerae 3 ~ 7 parts, Fructus Forsythiae 4 ~ 13 parts, Radix Angelicae Sinensis 15 ~ 20 parts, Rhizoma Smilacis Glabrae 12 ~ 17 parts, Radix Scrophulariae 7 ~ 15 parts, Caulis Spatholobi 14 ~ 21 parts, the Radix Polygoni Multiflori 5 ~ 10 parts.
2. herbal composite as claimed in claim 1, is characterized in that, be made up of the raw material of Chinese medicine of following weight parts: 8 parts, the Radix Rehmanniae, Radix Paeoniae Rubra 11 parts, Rhizoma Coptidis 5 parts, Radix Ophiopogonis 10 parts, Flos Lonicerae 4 parts, Fructus Forsythiae 5 parts, Radix Angelicae Sinensis 16 parts, Rhizoma Smilacis Glabrae 12 parts, Radix Scrophulariae 7 parts, Caulis Spatholobi 15 parts, the Radix Polygoni Multiflori 7 parts.
3. herbal composite as claimed in claim 1, is characterized in that, be made up of the raw material of Chinese medicine of following weight parts: 10 parts, the Radix Rehmanniae, Radix Paeoniae Rubra 9 parts, Rhizoma Coptidis 8 parts, Radix Ophiopogonis 13 parts, Flos Lonicerae 6 parts, Fructus Forsythiae 10 parts, Radix Angelicae Sinensis 18 parts, Rhizoma Smilacis Glabrae 15 parts, Radix Scrophulariae 11 parts, Caulis Spatholobi 17 parts, the Radix Polygoni Multiflori 9 parts.
4. treat a preparation method for psoriasic herbal composite, it is characterized in that, take raw material by formula, insert in marmite and add cold water soak 20 ~ 30 minutes, add a cover decoction; First decoct with high heat, then use slow fire boiling; Slow fire boiling is after 10 ~ 15 minutes, and leaching is medicinal liquid for the first time; Heating water is appropriate, decocts according to upper method, gets second time medicinal liquid; By twice liquid medicine mixing and get final product.
CN201410494494.3A 2014-09-25 2014-09-25 Chinese herbal medicine composition for treating psoriasis and preparation method thereof Pending CN104258210A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104689056A (en) * 2015-03-23 2015-06-10 高旭 Soft capsule for treating psoriasis and preparation method thereof
CN107496785A (en) * 2017-09-29 2017-12-22 南京科兴新材料科技有限公司 One kind treats psoriasis medicament

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104689056A (en) * 2015-03-23 2015-06-10 高旭 Soft capsule for treating psoriasis and preparation method thereof
CN107496785A (en) * 2017-09-29 2017-12-22 南京科兴新材料科技有限公司 One kind treats psoriasis medicament

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