CN103330803A - Chinese medicinal composition for vasculitis - Google Patents
Chinese medicinal composition for vasculitis Download PDFInfo
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- CN103330803A CN103330803A CN2013102766843A CN201310276684A CN103330803A CN 103330803 A CN103330803 A CN 103330803A CN 2013102766843 A CN2013102766843 A CN 2013102766843A CN 201310276684 A CN201310276684 A CN 201310276684A CN 103330803 A CN103330803 A CN 103330803A
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Abstract
The invention discloses a Chinese medicinal composition for vasculitis. The composition is composed of monkshood, radix aconiti agrestis, lycopodium clavatum, rhizoma cyperi, corydalis tuber, medicinal cyathula root, Radix Paeoniae Alba, cassia twig, radix clematidis,safflower, Caulis Spatholobi, Astragalus membranaceus, Ligusticum wallichii,angelica, Salvia miltiorrhiza, pangolin, spina Gleditsiae and sargentgloryvine stem according to a certain weight ratio. The composition has efficacies of promoting blood circulation, removing blood stasis, dispelling cold, relieving pain, dredging collaterals and promoting granulation, and can effectively treat vasculitis.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of for vasculitic Chinese medicine composition.
Background technology
Vasculitis, full name " thromboangiitis obliterans " is the allergic inflammation that betides blood vessel, small artery segmental stricture, obturation in causing, acra loses nutrition, ulcer occurs, necrosis, is a kind of obstinate angiopathy, is not that a kind of inflammation of blood vessel wall itself shows.Belong to the traditional Chinese medical science " necrosis " category.The traditional Chinese medical science thinks that the generation of primary disease because of the heart, spleen, deficiency of the kidney void, feels the heresy of cold-damp again, makes the meridian stasis resistance, and yang-energy can not the Wen Dasi end, and acra loses in keeping, strongly fragrant evil heat-transformation, and cause " necrosis ".Chinese traditional treatment is mainly with blood circulation promoting and blood stasis dispelling, and the dispersing cold for relieving pain method is improved or corrected disturbance of blood circulation, especially microcirculation disturbance, increases blood flow and removes whole body or local hematogenous blockage.The Chinese medicine vasculitis is evident in efficacy, is worth promoting clinically.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition, this Chinese medicine composition has determined curative effect, characteristics easy and simple to handle, cheap for the treatment vasculitis.
The present invention selects Radix Aconiti Lateralis Preparata, Radix Aconiti Kusnezoffii, Herba Lycopodii, Rhizoma Cyperi, Rhizoma Corydalis, Radix Cyathulae, the Radix Paeoniae Alba, Ramulus Cinnamomi, Radix Clematidis, Flos Carthami, Caulis Spatholobi, the Radix Astragali, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Squama Manis, Spina Gleditsiae, Caulis Sargentodoxae to make up, make each efficacy of drugs produce synergism these drug regimens, make it to have blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain, the effect of collateral dredging granulation promoting, thus vasculitis can effectively be treated.
The effect of Chinese medicine of the present invention:
Wherein:
Radix Aconiti Lateralis Preparata: be the processed goods of the daughter root of ranunculaceae plant Aconitum carmichjaelii Debx. Aconitum carmichaeli Debx..Nature and flavor suffering, sweet, big heat; Poisonous.GUIXIN, kidney, spleen channel.Effect: recuperating depleted YANG and rescuing the patient from collapse, it is supporing yang to mend fire, dispersing cold for relieving pain.
Radix Aconiti Kusnezoffii: be the dried root of ranunculaceae plant Aconitum kusnezoffii Reichb Aconitum kusnezoffii Reichb..The nature and flavor suffering, heat, poisonous.Go into liver, spleen, lung meridian.Effect: search wind prevailing over dampness, dispersing cold for relieving pain is opened expectorant, detumescence.
Herba Lycopodii: be the dry herb of lycopsid Lycopodium clavatum Lycopodium japonicum Thunb..Nature and flavor hardship, suffering, temperature.Go into Liver Channel.Effect: expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral.
Rhizoma Cyperi: be the dry rhizome of sedge dried tuber.Nature and flavor are slightly cold, and are sweet, nontoxic.Go into liver, tri-jiao channel.Effect: the resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving.
Rhizoma Corydalis: be the dry tuber of papaveraceae plant corydalis.Nature and flavor suffering, hardship, temperature; Nontoxic.Go into pericardium, liver, spleen, lung meridian.Effect: promoting blood circulation to remove blood stasis, regulating QI to relieve pain.
Radix Cyathulae: be the dry root of amaranthaceous plant Radix Cyathulae Cyathula officinalis Kuan.Sweet, the little hardship of nature and flavor, flat.Return liver, kidney channel.Effect: blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness.
The Radix Paeoniae Alba: be the root of dicotyledon medicine ranunculaceae plant Radix Paeoniae (cultigen).Nature and flavor are slightly cold, and are bitter, sour.Return liver, spleen channel.Effect: nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.
Ramulus Cinnamomi: be the dry twig of canella Cortex Cinnamomi Cinnamomum cassia Presl.Nature and flavor suffering, sweet, temperature.GUIXIN, lung, urinary bladder channel.Effect: diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain.
Radix Clematidis: be the dry root and rhizome of ranunculaceae plant Radix Clematidis Clematis chinensis Osbeck, Clematis hexapetala Clematis hexapetala Pall. or northeast clematis Clematis manshurica Rupr..Nature and flavor suffering, salty, temperature, poisonous.Go into urinary bladder channel.Effect: expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the hypochondriac lump of loosing.
Flos Carthami: be the tubular corolla of feverfew Flos Carthami Carthamus tinctorius L..The nature and flavor temperature, suffering.GUIXIN, Liver Channel.Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.Flos Carthami has analgesic activity.
Caulis Spatholobi: be the dry rattan of leguminous plant spatholobus suberectus Spatholobus suberectus Dunn.Nature and flavor hardship, sweet, temperature.Return liver, kidney channel.Effect: relaxing muscles and tendons to promote blood circulation, nourishing blood for regulating menstruation.
The Radix Astragali: be the root of leguminous herbaceous plant's Radix Astagali, Radix Astragali.Nature and flavor are sweet, tepor.Return lung, spleen, liver, kidney channel.Effect: benefiting QI for strengthening the superficies, arresting sweating take off, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema admittedly.
Rhizoma Chuanxiong: be the dry rhizome of samphire Rhizoma Chuanxiong Ligusticum chuanxiong Hort..The nature and flavor suffering, temperature.Return liver, gallbladder, pericardium channel.Effect: blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping.
Radix Angelicae Sinensis: be umbelliferae angelica Angelica sinensis(Oliv.) root of Diels.The nature and flavor temperature, sweet, hot.Return liver, the heart, spleen channel.Effect: enrich blood and invigorate blood circulation, pain relieving.
Radix Salviae Miltiorrhizae: be the dry root and rhizome of dicotyledon Labiatae Labiatae salvia Radix Salviae Miltiorrhizae Salvia miltiorrhiza Bge..The nature and flavor hardship is slightly cold.Go into the heart, Liver Channel.Effect: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind.
Squama Manis: be the scute of Manidae animal Squama Manis Manis pentadactyla Linnaeus.Nature and flavor are salty, are slightly cold.Return liver, stomach warp.Effect: blood circulation promoting and dispersing pathogen accumulation, the stimulating milk secretion of stimulating the menstrual flow, eliminating carbuncle is burst hard.
Spina Gleditsiae: be the Spina jujubae of leguminous plant Fructus Gleditsia.The nature and flavor suffering, temperature.Return lung, Liver Channel.Effect: promoting blood circulation by removing wind, detumescence and apocenosis.
Caulis Sargentodoxae: be the dry rattan of Lardizabalaceae plant Caulis Sargentodoxae Sargentodoxa cuneata (Oliv.) Rehd. et wils..The nature and flavor hardship, flat.Go into liver, large intestine channel.Effect: the eliminating carbuncle that relieves internal heat, promoting blood circulation to remove obstruction in the collateral, wind dispelling insecticide.
Medicine material consumption of the present invention is groped to sum up to draw through the inventor in a large number, and each raw material consumption is for all to have curative effect preferably in the following weight parts scope: Radix Aconiti Lateralis Preparata 10-20 part, Radix Aconiti Kusnezoffii 7-17 part, Herba Lycopodii 15-25 part, Rhizoma Cyperi 10-20 part, Rhizoma Corydalis 15-25 part, Radix Cyathulae 15-25 part, Radix Paeoniae Alba 10-20 part, Ramulus Cinnamomi 19-29 part, Radix Clematidis 19-29 part, Flos Carthami 5-15 part, Caulis Spatholobi 25-35 part, Radix Astragali 55-65 part, Rhizoma Chuanxiong 7-17 part, Radix Angelicae Sinensis 10-20 part, Radix Salviae Miltiorrhizae 25-35 part, Squama Manis 3-9 part, Spina Gleditsiae 19-29 part, Caulis Sargentodoxae 19-29 part.
Wherein be preferably: 15 parts of Radix Aconiti Lateralis Preparatas, 12 parts of Radix Aconiti Kusnezoffii, 20 parts of Herba Lycopodiis, 15 parts of Rhizoma Cyperis, 20 parts of Rhizoma Corydalis, 20 parts of Radix Cyathulaes, 15 parts of the Radix Paeoniae Albas, 24 parts of Ramulus Cinnamomi, 24 parts of Radix Clematidis, 10 parts on Flos Carthami, 30 parts of Caulis Spatholobis, 60 parts of the Radixs Astragali, 12 parts of Rhizoma Chuanxiongs, 15 parts of Radix Angelicae Sinensis, 30 parts of Radix Salviae Miltiorrhizaes, 6 parts of Squama Maniss, 24 parts of Spina Gleditsiaes, 24 parts of Caulis Sargentodoxae.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into powder.Specifically these crude drug pulverize mix homogeneously can be made powder, decocting becomes the decoction washout.
Medicine of the present invention has blood circulation promoting and blood stasis dispelling, dispersing cold for relieving pain, and effects such as collateral dredging granulation promoting, and determined curative effect, easy and simple to handle, cheap, according to clinical 100 routine patients being observed statistics, use medicine total effective rate course for the treatment of total effective rate 80%, two course for the treatment of 95% of the present invention.
The specific embodiment
Embodiment one, 10 parts of Radix Aconiti Lateralis Preparatas, 7 parts of Radix Aconiti Kusnezoffii, 15 parts of Herba Lycopodiis, 10 parts of Rhizoma Cyperis, 15 parts of Rhizoma Corydalis, 15 parts of Radix Cyathulaes, 10 parts of the Radix Paeoniae Albas, 19 parts of Ramulus Cinnamomi, 19 parts of Radix Clematidis, 5 parts on Flos Carthami, 25 parts of Caulis Spatholobis, 55 parts of the Radixs Astragali, 7 parts of Rhizoma Chuanxiongs, 10 parts of Radix Angelicae Sinensis, 25 parts of Radix Salviae Miltiorrhizaes, 3 parts of Squama Maniss, 19 parts of Spina Gleditsiaes, 19 parts of Caulis Sargentodoxae.
Embodiment two, 15 parts of Radix Aconiti Lateralis Preparatas, 12 parts of Radix Aconiti Kusnezoffii, 20 parts of Herba Lycopodiis, 15 parts of Rhizoma Cyperis, 20 parts of Rhizoma Corydalis, 20 parts of Radix Cyathulaes, 15 parts of the Radix Paeoniae Albas, 24 parts of Ramulus Cinnamomi, 24 parts of Radix Clematidis, 10 parts on Flos Carthami, 30 parts of Caulis Spatholobis, 60 parts of the Radixs Astragali, 12 parts of Rhizoma Chuanxiongs, 15 parts of Radix Angelicae Sinensis, 30 parts of Radix Salviae Miltiorrhizaes, 6 parts of Squama Maniss, 24 parts of Spina Gleditsiaes, 24 parts of Caulis Sargentodoxae.
Embodiment three, 20 parts of Radix Aconiti Lateralis Preparatas, 17 parts of Radix Aconiti Kusnezoffii, 25 parts of Herba Lycopodiis, 20 parts of Rhizoma Cyperis, 25 parts of Rhizoma Corydalis, 25 parts of Radix Cyathulaes, 20 parts of the Radix Paeoniae Albas, 29 parts of Ramulus Cinnamomi, 29 parts of Radix Clematidis, 15 parts on Flos Carthami, 35 parts of Caulis Spatholobis, 65 parts of the Radixs Astragali, 17 parts of Rhizoma Chuanxiongs, 20 parts of Radix Angelicae Sinensis, 35 parts of Radix Salviae Miltiorrhizaes, 9 parts of Squama Maniss, 29 parts of Spina Gleditsiaes, 29 parts of Caulis Sargentodoxae.
Be the clinical statistics data that the patient uses medicine of the present invention below:
One, physical data
Accept out-patient's totally 100 examples for medical treatment, male's 72 examples wherein, women's 28 examples, M-F 2.6:1,31 years old mean age.
Two, tcm diagnosis standard
1, is mainly in the lower limb one or both sides.The patient can be subjected to, and freezing, moist, long-term volume is inhaled medical histories such as pharynx, wound.
2, from the beginning of toe, refer to cold type of pain, the tingle distending pain of shank, the walking increase the weight of for a long time, alleviate during rest, be intermittent claudication, FU YANG pulse the pulse of anterior tibial artery weakens, shank can have migration acute thrombophlebitis (phlebitis).The pain that continues is persistence, and acra skin is sent out cold, and then skin is dark red, livid purple when sagging, xerosis cutis, and hair comes off, and the toenail distortion thickens, amyotrophy, FU YANG pulse the pulse of anterior tibial artery disappears.And then the necrosis of betiding property, sharp ache is lain awake all night, and sits with one's arms about one's knees.When festering contamination, moist necrosis appears, acra red and swollen heat pain, whole body heating.
3, the patient mostly is 20～40 years old male greatly.Arteriosclerosis obliterans is mainly in the old people.
4, ultrasonic doppler, rheography, nail fold microcirculation, angiography, X line chest are taken the photograph inspections such as sheet, blood-fat and blood sugar, except assisted diagnosis, still can understand vascular occlusion position and degree.
Three, using method
According to drug weight proportioning of the present invention, every day the weighting raw materials potion, washout affected part behind the decocting.30 days is a course for the treatment of.
Four, efficacy assessment standard
Cure: suffer from limb pain and disappear, color of the leather, skin temperature are recovered normally, wound healing, the stride activity freely, or FU YANG pulse the pulse of anterior tibial artery can be touched.
Take a turn for the better: pain disappears substantially, but the stride activity can not be lasting, and open sore part scope is dwindled.
Do not heal: pain can not be controlled, and ulcer can not heal, or continues to develop to near-end.
Five, therapeutic outcome statistics
Wherein: total effective rate=cure rate+improvement rate
Model case and curative effect:
Case one, Zhang, the man 35 years old, occurred before 3 years that biped is sent out cold, the symptom of being afraid of cold, not diagnosis and treatment always; Sent out cool obvious, left sufficient pain because of biped before half a year, soak with the hot water foot voluntarily, blister appears in left skin of dorsum of foot, and left skin of dorsum of foot blackening in succession checks white and greasy fur, deep-thready pulse, and FU YANG pulse the pulse of anterior tibial artery weakens.Be diagnosed as: two thromboangiitis obliterans of lower limb.The patient uses external washout with traditional Chinese herbs of the present invention after course for the treatment of, pain and be afraid of cool transference cure.
Case two, Wu, the man 43 years old, examines and states the cold of right foot, is afraid of cold intermittent cyllopodia two days.Right leg is felt nervous and with distending pain, the inspection foot is aubergine when standing, thin white fur of tongue, and deep red tongue, stringy pulse is slow.Be diagnosed as: the right lower extremity thromboangiitis obliterans.The patient uses Chinese medicine of the present invention after course for the treatment of, and all diseases disappear, and are almost recovered.
Case three, Liu, the man, 26 years old, examine and state left leg pain, stride inconvenience, the pain increased during night, and time sense is numb, checks patient's face Huang Shaohua, and spirit is stranded tired, and the shank color of the leather is not bright, and deep-thready pulse is puckery, purplish tongue.Be diagnosed as: the left lower extremity thromboangiitis obliterans.The patient uses Chinese medicine of the present invention after two courses for the treatment of, clinical symptom disappearance.
Claims (2)
1. one kind is used for vasculitic Chinese medicine composition, it is characterized in that this Chinese medicine composition is made up of following medicaments in part by weight: Radix Aconiti Lateralis Preparata 10-20 part, Radix Aconiti Kusnezoffii 7-17 part, Herba Lycopodii 15-25 part, Rhizoma Cyperi 10-20 part, Rhizoma Corydalis 15-25 part, Radix Cyathulae 15-25 part, Radix Paeoniae Alba 10-20 part, Ramulus Cinnamomi 19-29 part, Radix Clematidis 19-29 part, Flos Carthami 5-15 part, Caulis Spatholobi 25-35 part, Radix Astragali 55-65 part, Rhizoma Chuanxiong 7-17 part, Radix Angelicae Sinensis 10-20 part, Radix Salviae Miltiorrhizae 25-35 part, Squama Manis 3-9 part, Spina Gleditsiae 19-29 part, Caulis Sargentodoxae 19-29 part.
2. described for vasculitic Chinese medicine composition according to claims 1, it is characterized in that, formed by following medicaments in part by weight: 15 parts of Radix Aconiti Lateralis Preparatas, 12 parts of Radix Aconiti Kusnezoffii, 20 parts of Herba Lycopodiis, 15 parts of Rhizoma Cyperis, 20 parts of Rhizoma Corydalis, 20 parts of Radix Cyathulaes, 15 parts of the Radix Paeoniae Albas, 24 parts of Ramulus Cinnamomi, 24 parts of Radix Clematidis, 10 parts on Flos Carthami, 30 parts of Caulis Spatholobis, 60 parts of the Radixs Astragali, 12 parts of Rhizoma Chuanxiongs, 15 parts of Radix Angelicae Sinensis, 30 parts of Radix Salviae Miltiorrhizaes, 6 parts of Squama Maniss, 24 parts of Spina Gleditsiaes, 24 parts of Caulis Sargentodoxae.
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| CN201310276684.3A CN103330803B (en) | 2013-07-03 | 2013-07-03 | Chinese medicinal composition for vasculitis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103830426A (en) * | 2014-03-28 | 2014-06-04 | 广州市中医医院 | Traditional Chinese medicine composition for treating angiitis |
| CN110151853A (en) * | 2019-03-21 | 2019-08-23 | 江苏康缘药业股份有限公司 | A kind of application of Chinese medicine composition in preparation treatment phlebitis drug |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101053632A (en) * | 2006-04-13 | 2007-10-17 | 吴希文 | Traditional Chinese medicine for treating thromboangitis obliterans |
| CN102526259A (en) * | 2010-12-13 | 2012-07-04 | 陈冠卿 | Drug for curing rheumatoid arthritis |
-
2013
- 2013-07-03 CN CN201310276684.3A patent/CN103330803B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101053632A (en) * | 2006-04-13 | 2007-10-17 | 吴希文 | Traditional Chinese medicine for treating thromboangitis obliterans |
| CN102526259A (en) * | 2010-12-13 | 2012-07-04 | 陈冠卿 | Drug for curing rheumatoid arthritis |
Non-Patent Citations (3)
| Title |
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| 付革新等: "中西医结合治疗血栓闭塞性脉管炎40例", 《河北中医》, vol. 22, no. 08, 28 August 2000 (2000-08-28), pages 623 * |
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| 李咏梅等: "辨证治疗50例系统性硬皮病临床总结", 《新中医》, vol. 30, no. 08, 15 August 1998 (1998-08-15) * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103830426A (en) * | 2014-03-28 | 2014-06-04 | 广州市中医医院 | Traditional Chinese medicine composition for treating angiitis |
| CN110151853A (en) * | 2019-03-21 | 2019-08-23 | 江苏康缘药业股份有限公司 | A kind of application of Chinese medicine composition in preparation treatment phlebitis drug |
| CN110151853B (en) * | 2019-03-21 | 2021-07-23 | 江苏康缘药业股份有限公司 | Application of traditional Chinese medicine composition in preparation of medicine for treating phlebitis |
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