CN102670773A - Chinese herba preparation for treating scleroderma - Google Patents

Chinese herba preparation for treating scleroderma Download PDF

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Publication number
CN102670773A
CN102670773A CN2012101363431A CN201210136343A CN102670773A CN 102670773 A CN102670773 A CN 102670773A CN 2012101363431 A CN2012101363431 A CN 2012101363431A CN 201210136343 A CN201210136343 A CN 201210136343A CN 102670773 A CN102670773 A CN 102670773A
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weight
parts
chinese medicine
scleroderma
medicine preparation
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CN2012101363431A
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谢培德
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Chengdu LVDI Technology Co Ltd
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Chengdu LVDI Technology Co Ltd
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Priority to CN2012101363431A priority Critical patent/CN102670773A/en
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Abstract

The invention provides a Chinese herba preparation for treating scleroderma, which comprises 28 to 32 parts by weight of astragalus, 12 to 18 parts by weight of codonopsis pilosula, 9 to 15 parts by weight of largehead atractylodesRhizome, 12 to 18 parts by weight of poria cocos, 8 to 12 parts by weight of angelica, 8 to 12 parts by weight of ligusticum wallichii, 7 to 11 parts by weight of peach kernels, 7 to 11 parts by weight of safflowers and 12 to 18 parts by weight of suberect spatholobus stems. Compared with prior art, the Chinese herba preparation for treating the scleroderma distinguishes distinction to treat aiming at inner disease evil of scleroderma, is rapid in curative effect and low in cost, does not have side effect, is obvious in effect, and treats both principal and secondary aspect of diseases.

Description

A kind of Chinese medicine preparation of treating scleroderma
Technical field
The present invention relates to a kind of Chinese medicine, more particularly, relate to a kind of Chinese medicine preparation of treating scleroderma.
Background technology
Scleroderma is a kind of agnogenic autoimmune disease, and is pale or light red with hydroderma, the xerosis cutis that continues, smooth, thicken, hardening, attenuation, alopecia, finger tip and joint are prone to intractable ulcer etc. and are main clinical characteristics.The swelling phase is experienced in typical skin lesion successively, infiltration stage and atrophy phase three phases.Pathological changes is symmetry, and pathological changes is many by pointing gradually to proximal spread, and the boundary of affected skin and normal skin is unclear.Primary disease has the branch of limitation and systematicness, and the former is confined to skin and muscle damage, and in addition the latter still involves internal organs.The scleroderma age of onset to see 20~50 years old more, and the women is more than the male.Limitation person prognosis bona, systemic person, in case lung, the heart, kidney are got involved, the state of an illness worsens rapidly, prognosis is relatively poor.Scleroderma belongs to categories such as the traditional Chinese medical science " BI-syndrome involved the muscle ", " BI-syndrome related to skin ".For the treatment of scleroderma, doctor trained in Western medicine adopts vasoactive agent and connective tissue to form inhibitor for treating more, disease is had certain inhibitory action, but need life-time service, and side effect is more, and curative effect is very not remarkable again.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine preparation of treating scleroderma, it is to the inherent pathogenic factor of scleroderma, distinguishes that disease executing control, and with strong points, curative effect is fast, and cost is low, and has no side effect, and can reach to play good prevention effect.
In order to realize above-mentioned purpose, the present invention adopts following technical scheme: a kind of Chinese medicine preparation of treating scleroderma, in weight portion; Comprise following component: Radix Astragali 28-32, Radix Codonopsis 12-18, Rhizoma Atractylodis Macrocephalae 9-15; Poria 12-18, Radix Angelicae Sinensis 8-12, Rhizoma Chuanxiong 8-12; Semen Persicae 7-11, Flos Carthami 7-11, Caulis Spatholobi 12-18.
The Analysis on Mechanism of Chinese medicine of the present invention:
The Radix Astragali: sweet, tepor.Return lung, spleen, liver, kidney channel.There are benefiting QI for strengthening the superficies, arresting sweating to take off, hold in the palm the effect of skin ulcer granulation promoting, inducing diuresis to remove edema admittedly.
Radix Codonopsis: sweet in the mouth; Property is put down.Return spleen; Lung meridian.Strengthening the spleen and tonifying the lung, supplementing QI for promoting the production of body fluid.Cure mainly weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung breath with cough, breathe hard spontaneous perspiration, feeble QI two and lose all cards." Bencao Congxin ": invigorating the spleen and replenishing QI and taste relieving thirst and restlessness.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth; Sweet; Warm in nature.Return spleen; The stomach warp.Invigorating the spleen and benefiting QI; The dampness diuretic; Hidroschesis.Be used for deficiency-weakness of spleen-QI; Spiritlessness and weakness." herbal classic is met former ": the Rhizoma Atractylodis Macrocephalae, it is living that the expectorant diuretic is controlled anemofrigid-damp arthralgia with there being the dehumidifying benefit dry, dead flesh convulsion subcutaneous ulcer, the blood between the waist umbilicus that looses, reaching chong channel is disease, the merit of contrary gas pain in the abdomen; Making ripely then has and middle QI invigorating, slakes thirst and help produce saliva, and the hidroschesis heat extraction advances diet, antiabortive effect.
Poria: slightly sweet flavor is flat, goes into the heart, lung, spleen channel.Eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming." herbal classic ": the contrary gas of the main breast side of body, melancholy is angerd frightened heresy and is probably throbbed with fear, and the heart is the knot pain down, cold and heat stuffy sensation with restlessness, cough with dyspnea, mouthful burnt dry tongue, diuresis.
Radix Angelicae Sinensis: warm in nature, hide sweet, hot.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Materia Medica of Decoction: Radix Angelicae Sinensis, few the moon of starting with, with its heart master blood also; It is lunar to go into foot, wraps up in blood also with its spleen; Go into the sufficient the moon of fainting, also with its blood stored in the liver.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping." herbal classic ": main apoplexy is gone into the brain headache, arthralgia due to cold, and the clonic spasm of the muscle emergency, the gold wound, married woman's blood closes loss of fecundity.
Semen Persicae: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.Be used for amenorrhea, dysmenorrhea , WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation." medication heart method ": Semen Persicae, bitter to let out stagnant blood, sweet with tissue regeneration promoting blood, so blood coagulation must be used.Heat in dehematizing again.
Flos Carthami: warm in nature, acrid in the mouth.GUIXIN, Liver Channel.Promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.Be used for that amenorrhea, dysmenorrhea, lochia are not all right, lump in the abdomen mass in the abdomen, traumatic injury.
Caulis Spatholobi: bitter, sweet, temperature.Return liver, kidney channel.Relaxing muscles and tendons to promote blood circulation; Nourishing blood for regulating menstruation.Supplementary Amplifications of the Compendium of Materia Medica: invigorate blood circulation warm waist knee joint, paralysis.
To the scleroderma due to the deficient vital QI leading to lingering of pathogen, the traditional Chinese medical science thinks evil and loves with the passing of time that healthy energy is lost QI and blood deficiency greatly, and the five internal organs lose supports.Heart master blood, lung governing qi, cardiopulmonary lose supports then pallor, nervous breathing hard; Spleen governing muscles, main extremity, kidney controlling essence storage is given birth to marrow and is filled brain, and the spleen kidney loses supports, and then the thin limb of shape is tired, dizzy alopecia; Because of the void stasis of blood, integumentary musculature lose for a long time moisten in QI and blood foster, myalgia then, skin is thin like hard paper, the colour of skin is withered; Light red tongue, thin fur, thready and weak pulse is healthy energy and loses greatly, the levying of QI and blood deficiency.
The person of choosing in the side, benefiting QI and nourishing blood, promoting blood circulation to remove obstruction in the collateral, Radix Astragali benefiting QI for strengthening the superficies, the Radix Codonopsis supplementing QI for promoting the production of body fluid, Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI, the Poria invigorating the spleen and regulating the stomach, Chinese angelica blood supplementing is invigorated blood circulation, Rhizoma Chuanxiong, Semen Persicae blood circulation promoting and blood stasis dispelling, Flos Carthami promoting blood circulation to restore menstrual flow, Caulis Spatholobi nourishing blood for regulating menstruation.To scleroderma determined curative effect due to the deficient vital QI leading to lingering of pathogen, prevention effect is remarkable, doublely takes stopgap measures this.
Form of Chinese drug of the present invention can adopt tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.Preferably, can adopt solution, granule, pill and capsule.
Result of use
To the Chinese medicine of 30 scleroderma patients (age 35-50) use treatment scleroderma of the present invention, 1 course of treatment of continued treatment (2 months), wherein 8 examples are cured fully; 18 routine remissions; Invalid 4 examples, overall effective percentage reaches 86.7%, and does not have recurrence.
Instance:
The patient 1: the Shandong, and the women, 40 years old, myalgia, the skin of face change tightly approaches, the colour of skin is withered, points swollen firmly.Take Chinese medicine of the present invention after one month, remission, continued was taken medicine to 1 course of treatment, and transference cure does not have recurrence so far half a year.
The patient 2: the week certain, the male, 50 years old, the dorsal cutaneous complexion changed was pale before 1 month, forearm muscle feel nervous swelling, ache, the colour of skin dries up, hardens, the trend that symptom does not alleviate, then affected area skin begins to thicken, and follows the string gradually.Be diagnosed as scleroderma, take Chinese medicine of the present invention after 1 course of treatment, above-mentioned symptom all disappears, and does not see outbreak so far half a year.
The patient 3: Guo, and the women, 35 years old, Raynaud phenomenon appearred before 2 weeks, and finger skin is pale, becomes stasis of blood green grass or young crops, flushing when disease is sent out, and has numbness and prickling sensation, and blood circulation is not smooth, light red tongue, thin fur.Ulcer appears in the finger part.Be diagnosed as scleroderma, the back uses Chinese medicine of the present invention to treat, and after half course of treatment, above-mentioned symptom is eased, and the sx of ulcer skin lesion continued to take medicine to 1 course of treatment, and above-mentioned symptom all disappears, and does not have recurrence so far.
The specific embodiment
In order to understand the present invention better, through embodiment the present invention is described below.
Embodiment 1
A kind of Chinese medicine preparation of treating scleroderma in weight portion, comprises following component: the Radix Astragali 28, Radix Codonopsis 12, the Rhizoma Atractylodis Macrocephalae 9, Poria 12, Radix Angelicae Sinensis 8, Rhizoma Chuanxiong 8, Semen Persicae 7, Flos Carthami 7, Caulis Spatholobi 12.
Its preparation method is:
In weight portion, get the Radix Astragali 28, Radix Codonopsis 12, the Rhizoma Atractylodis Macrocephalae 9, Poria 12, Radix Angelicae Sinensis 8, Rhizoma Chuanxiong 8, Semen Persicae 7, Flos Carthami 7, Caulis Spatholobi 12; Above-mentioned Chinese medicine is cleaned, and decontamination is put into container and is added water and do not have medical material to soak, and after 30 minutes, big fire decocts to boiling, and slow fire was endured 1 hour slowly then; Medicine juice is leached, bag distribution packaging, one bag of 200ml sooner or later respectively obeys one bag.
Embodiment 2
A kind of Chinese medicine preparation of treating scleroderma in weight portion, comprises following component: the Radix Astragali 32, Radix Codonopsis 18, the Rhizoma Atractylodis Macrocephalae 15, Poria 18, Radix Angelicae Sinensis 12, Rhizoma Chuanxiong 12, Semen Persicae 11, Flos Carthami 11, Caulis Spatholobi 18.
Its preparation method is:
In weight portion, get the Radix Astragali 32, Radix Codonopsis 18, the Rhizoma Atractylodis Macrocephalae 15, Poria 18, Radix Angelicae Sinensis 12, Rhizoma Chuanxiong 12, Semen Persicae 11, Flos Carthami 11, Caulis Spatholobi 18; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; The packing of granule racking machine promptly gets granule.
Embodiment 3
A kind of Chinese medicine preparation of treating scleroderma in weight portion, comprises following component: the Radix Astragali 30, Radix Codonopsis 15, the Rhizoma Atractylodis Macrocephalae 12, Poria 15, Radix Angelicae Sinensis 10, Rhizoma Chuanxiong 10, Semen Persicae 9, Flos Carthami 9, Caulis Spatholobi 15.
Its preparation method is:
In weight portion, get the Radix Astragali 30, Radix Codonopsis 15, the Rhizoma Atractylodis Macrocephalae 12, Poria 15, Radix Angelicae Sinensis 10, Rhizoma Chuanxiong 10, Semen Persicae 9, Flos Carthami 9, Caulis Spatholobi 15; Cleaning, drying mix above-mentioned medical material, use pulverizer to pulverize and are 150-180 order fine powder, and add suitable Mel and mix, the pellet processing machine pill, cold drying, packing promptly gets pill.
Embodiment 4
A kind of Chinese medicine preparation of treating scleroderma in weight portion, comprises following component: the Radix Astragali 30, Radix Codonopsis 15, the Rhizoma Atractylodis Macrocephalae 12, Poria 15, Radix Angelicae Sinensis 10, Rhizoma Chuanxiong 10, Semen Persicae 9, Flos Carthami 9, Caulis Spatholobi 15.
Its preparation method is:
In weight portion, get the Radix Astragali 30, Radix Codonopsis 15, the Rhizoma Atractylodis Macrocephalae 12, Poria 15, Radix Angelicae Sinensis 10, Rhizoma Chuanxiong 10, Semen Persicae 9, Flos Carthami 9, Caulis Spatholobi 15; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, the back is concentrated into the clear paste of relative density 1.10-1.20 with concentrator, gets 2/3 clear paste 120 ℃ of following spray dryinges, the clear paste powder, powder is mixed granulation with residue 1/3 clear paste; Granule is processed the 0.4g/ capsules with the capsule filler.

Claims (4)

1. a Chinese medicine preparation of treating scleroderma is characterized in that, in weight portion, comprises following component: Radix Astragali 28-32, Radix Codonopsis 12-18, Rhizoma Atractylodis Macrocephalae 9-15, Poria 12-18, Radix Angelicae Sinensis 8-12, Rhizoma Chuanxiong 8-12, Semen Persicae 7-11, Flos Carthami 7-11, Caulis Spatholobi 12-18.
2. Chinese medicine preparation according to claim 1 is characterized in that, in weight portion, preferably comprises following component: the Radix Astragali 30, Radix Codonopsis 15, the Rhizoma Atractylodis Macrocephalae 12, Poria 15, Radix Angelicae Sinensis 10, Rhizoma Chuanxiong 10, Semen Persicae 9, Flos Carthami 9, Caulis Spatholobi 15.
3. Chinese medicine preparation according to claim 1 is characterized in that, said Chinese medicine preparation adopts tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.
4. Chinese medicine preparation according to claim 1 is characterized in that said Chinese medicine preparation preferably adopts solution, granule, pill and capsule.
CN2012101363431A 2012-05-04 2012-05-04 Chinese herba preparation for treating scleroderma Withdrawn CN102670773A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104689289A (en) * 2015-03-31 2015-06-10 潍坊医学院附属医院 Chinese herbal preparation for treating localized scleroderma
CN104857211A (en) * 2015-05-26 2015-08-26 河南中医学院 Traditional Chinese medicine for treating systemic sclerosis

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104689289A (en) * 2015-03-31 2015-06-10 潍坊医学院附属医院 Chinese herbal preparation for treating localized scleroderma
CN104857211A (en) * 2015-05-26 2015-08-26 河南中医学院 Traditional Chinese medicine for treating systemic sclerosis

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Application publication date: 20120919