CN104258184A - Powder for treating beriberi and preparation method thereof - Google Patents
Powder for treating beriberi and preparation method thereof Download PDFInfo
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Abstract
The invention discloses powder for treating beriberi and a preparation method thereof. The powder comprises the following components: pericarpium arecae, cortex acanthopanacis, pawpaw, rhizoma nardostachyos, radix stephaniae tetrandrae, fructus evodiae, rhizoma atractylodis, phaseolus calcaratus, bunge cherry seed, dolichos lablab, fenugreek, betel nut and coix seed. The preparation method comprises the following steps: (1) drying pericarpium arecae, cortex acanthopanacis, pawpaw, rhizoma nardostachyos, radix stephaniae tetrandrae, fructus evodiae, rhizoma atractylodis, phaseolus calcaratus, bunge cherry seed, dolichos lablab, fenugreek, betel nut and coix seed for later use; (2) sterilizing pericarpium arecae, cortex acanthopanacis, pawpaw, rhizoma nardostachyos, radix stephaniae tetrandrae, fructus evodiae, rhizoma atractylodis, phaseolus calcaratus, bunge cherry seed, dolichos lablab, fenugreek, betel nut and coix seed dried in the step (1) through ultraviolet rays; and (3) sufficiently stirring and mixing the raw materials sterilized in the step (2), grinding the materials into powder through a grinder, sieving, collecting powder, sealing and packaging depending on dosage. The powder disclosed by the invention not only has functions of clearing heat, promoting uresis, detoxifying and killing insects, but also can kill fungi effectively and cure beriberi; and the powder is gentle in efficacy and causes no injury to foot skin.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of powder for the treatment of beriberi and preparation method thereof.
Background technology
Beriberi, is medically referred to as tinea pedis, is because skin of sole of foot sweat gland is abundanter, perspires more, cause the wet environment being conducive to fungus growth, is a kind of extremely common fungal infection dermatoses.
At present, that treats beriberi has the ointment such as " daktarin ", " PIYANPING ", treats each have their own characteristic.But above-mentioned ointment all belongs to hormone medicine, prohibit the use there being the crowd of allergic constitution, and life-time service can produce digestive system and ulcer, osteoporosis, affect growth promoter, especially for child, upgrowth and development of children then can be made to have inhibitory action, also can make that human body is got fat, inducing neural mental symptom, as depression, and treatment is not dug up the roots, easy recurrent exerbation.
The traditional Chinese medical science is thought, primary disease mostly is damp and hot invasion and attack, and damp invasion of lower energizer is so-called, and when with clearing away heat-damp and promoting diuresis, removing toxic substances parasite killing, for controlling, adopts yin deficiency by soaking feet in Chinese medicament solution beriberi prescription to have huge effect for treatment beriberi.
Chinese patent CN 101972270 B discloses a kind of externally-applied powder preventing and treating beriberi, is made up of the raw material of following ratio of quality and the number of copies: zinc acetate 12 ~ 15 parts, 10 ~ 13 parts, benzoic acid, salicylic acid 9 ~ 12 parts, 5 ~ 8 parts, zinc sulfate.Though this technical scheme can killing fungus, prevent and treat the effect of beriberi, damage can be caused to foot's skin.
Chinese patent CN 102366574 A discloses the beriberic Chinese herbal medicine for external use powder for the treatment of, and this Chinese herbal medicine powder is made up of the medicine of following weight proportion: Herba Taraxaci 16 ~ 10 parts, Gypsum Fibrosum 10 ~ 30 parts, Mirabilitum crystallina 10 ~ 20 parts, Herba Rabdosiae glaucocalycis 6 ~ 10 parts, brave parent root 6 ~ 12 parts, Ramulus et Folium Phyllodii Pulchelli 6 ~ 12 parts, Melica scabrosa Trin. 10 ~ 15 parts, Desmos chinensis 6 ~ 12 parts, Herba Senecionis Scandentis 6 ~ 10 parts, Herba Melicae Scabrosae 10 ~ 15 parts, Tectaria subtriphlla (Hook. Et Arn.) 10 ~ 15 parts, Herba Pteridis Multifidae 10 ~ 15 parts.Although this technical scheme is furnished with the Chinese herbal medicine of multiple suppression beriberi, what play a major role is Gypsum Fibrosum, and Hui Shi foot produces the sequela of burning.
Summary of the invention
Based on above-mentioned information, the object of the present invention is to provide powder of a kind for the treatment of beriberi gentle, evident in efficacy with performance and preparation method thereof.
The technical scheme of the powder for the treatment of beriberi of the present invention is as follows:
A kind of powder for the treatment of beriberi, Main Ingredients and Appearance is herbal powder, described herbal powder by weight, comprises following component: Pericarpium Arecae 4 ~ 9 parts, Cortex Acanthopancis 4 ~ 9 parts, Fructus Chaenomelis 6 ~ 9 parts, Radix Et Rhizoma Nardostachyos 3 ~ 6 parts, Radix Stephaniae Tetrandrae 4 ~ 9 parts, Fructus Evodiae 1 ~ 5 part, Rhizoma Atractylodis 3 ~ 9 parts, Semen Phaseoli 9 ~ 30 parts, Semen Pruni 6 ~ 9 parts, Testa dolichoris 6 ~ 9 parts, Semen Trigonellae 4 ~ 9 parts, Semen Arecae 3 ~ 9 parts, Semen Coicis 9 ~ 30 parts.
Preferably, described herbal powder by weight, comprises following component: Pericarpium Arecae 5 ~ 8 parts, Cortex Acanthopancis 5 ~ 8 parts, Fructus Chaenomelis 7 ~ 9 parts, Radix Et Rhizoma Nardostachyos 4 ~ 6 parts, Radix Stephaniae Tetrandrae 4 ~ 8 parts, Fructus Evodiae 2 ~ 4 parts, Rhizoma Atractylodis 4 ~ 8 parts, Semen Phaseoli 10 ~ 25 parts, Semen Pruni 7 ~ 9 parts, Testa dolichoris 7 ~ 9 parts, Semen Trigonellae 5 ~ 8 parts, Semen Arecae 4 ~ 8 parts, Semen Coicis 10 ~ 25 parts.
More preferably, described herbal powder by weight, comprises following component: Pericarpium Arecae 7 parts, Cortex Acanthopancis 7 parts, Fructus Chaenomelis 8 parts, Radix Et Rhizoma Nardostachyos 5 parts, Radix Stephaniae Tetrandrae 6 parts, Fructus Evodiae 3 parts, Rhizoma Atractylodis 6 parts, Semen Phaseoli 20 parts, Semen Pruni 8 parts, Testa dolichoris 8 parts, Semen Trigonellae 6 parts, Semen Arecae 6 parts, Semen Coicis 20 parts.
Pericarpium Arecae, pungent, tepor.Return spleen, stomach, large intestine, small intestine meridian.Promoting the circulation of QI to alleviate the stagnation in middle-JIAO, inducing diuresis to remove edema.For retention of damp leading to blockage of QI, gastral cavity abdominal distention is vexed, defecates not well, edema distension, beriberi edema, dysuria.
Cortex Acanthopancis, pungent, bitter, temperature.Return liver, kidney channel.Expelling wind and removing dampness, liver and kidney tonifying, bone and muscle strengthening, inducing diuresis to remove edema.For Bi condition, muscles and bones flaccidity is soft, children's's walking retardation in children, and body void is weak, edema, beriberi.
Fructus Chaenomelis, acid, temperature.Return liver, spleen channel.Relaxing muscles and tendons and activating QI and blood in the collateral, stomach function regulating removing dampness.For arthralgia chiefly caused by damp pathogen contracture, the heavy pain of waist knee joint acid, heat-damp in summer is vomited and diarrhoea, convulsion spasm and pain, beriberi edema.
Radix Et Rhizoma Nardostachyos, pungent, sweet, warm.Return spleen, stomach warp.Regulating QI to relieve pain, relieving stagnation and activating the spleen, external damp eliminating is subsided a swelling.Take orally for distension and fullness in the abdomen, inappetence, vomiting; External treatment is used for toothache, beriberi toxic swelling.3～6g。Suitable amount used externally, bathingly gargles or decocts soup foot bath or grind deposited affected part into powder.
Radix Stephaniae Tetrandrae, bitter, cold.Return bladder, lung meridian.Wind-expelling pain-stopping, inducing diuresis to remove edema.For rheumatic arthralgia, edema beriberi, dysuria, eczema sore.
Fructus Evodiae is pungent, bitter, warm.Slightly poisonous.Return liver, spleen, stomach, kidney channel.Dispersing cold for relieving pain, stopping nausea and vomiting by lowering the adverse flow of QI, supporing yang antidiarrheal.For headache due to JUE YIN disorder, colic of cold type is suffered from abdominal pain, the disturbance of lower legs due to pathogenic cold and dampness, abdominal pain during menstruation, gastral cavity abdomen hypochondriac pain, vomiting acid regurgitation, Diarrhoea.
Rhizoma Atractylodis, pungent, bitter, temperature.Return spleen, stomach, Liver Channel.Drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For retention of dampness in middle-JIAO, distension and fullness in the abdomen, has loose bowels, edema, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia, and eyes dusk is puckery
Semen Phaseoli is sweet, sour, flat.GUIXIN, small intestine meridian.Inducing diuresis to remove edema, removing toxic substances and promoting pus discharge.For edema distension, beriberi edema, jaundice dark coloured urine, beriberoid pyretic arthralgia, carbuncle sore tumefacting virus, abdominalgia with intestinal abscess.Suitable amount used externally, grinds into powder and dresses.
Semen Pruni, pungent, bitter, sweet, flat.Return spleen, large intestine, small intestine meridian.Loosening bowel to relieve constipation, therapeutic method to keep the adverse QI flowing downwards diuretic.For intestine-dryness due to consumption of fluid, stagnation of QI due to dyspepsia, abdominal distention constipation, edema, beriberi, dysuria.
Testa dolichoris, sweet, flat.Return spleen, stomach warp.Invigorating the spleen and regulating the stomach, removing dampness of relieving summer heat.For accumulateing in heat-damp in summer, vomiting is had loose bowels, uncomfortable in chest indigestion and loss of appetite, beriberi edema, women's leukorrhagia.
Semen Trigonellae, bitter, temperature.Return kidney channel.Warming the kidney to activate YANG, cold-dispelling pain-relieving.For insufficiency of kidney-YANG, below element deficiency and cold, cold and pain in the lower abdomen, colic of cold type is suffered from abdominal pain, the disturbance of lower legs due to pathogenic cold and dampness.
Semen Arecae, bitter, pungent, temperature.Return stomach, large intestine channel.Parasite killing, removing food stagnancy, circulation of qi promoting, diuretic, preventing the attack (or recurrence) of malaria.For taeniasis, ascariasis, fasciolopsiasis buski, abdominal pain due to worm stagnation, stagnant dysentery, tenesmus, edema beriberi, malaria.
Semen Coicis is sweet, light, cool.Return spleen, stomach, lung meridian.Promoting diuresis to eliminate damp pathogen, invigorating the spleen to arrest diarrhea, eliminating impediment, evacuation of pus, detoxicating and resolving stagnation of pathogens.For edema, beriberi, dysuria, diarrhea due to hypofunction of the spleen, arthralgia chiefly caused by damp pathogen contracture, lung abscess, acute appendicitis, wart, cancerous protuberance.
Treat a preparation method for the powder of beriberi, comprise the steps:
(1) Pericarpium Arecae, Cortex Acanthopancis, Fructus Chaenomelis, Radix Et Rhizoma Nardostachyos, Radix Stephaniae Tetrandrae, Fructus Evodiae, Rhizoma Atractylodis, Semen Phaseoli, Semen Pruni, Testa dolichoris, Semen Trigonellae, Semen Arecae, Semen Coicis is taken, by weight, dry for standby;
(2) raw material irradiation-sterilize under uviol lamp of, being prepared by step (1);
(3), by raw material prepared by step (2) be fully uniformly mixed, be ground into powder body, sieve through pulverizer, collect powder body, divided dose packs.
Preferably, in step (1), bake out temperature is 40 ~ 60 DEG C, and drying time is 12 ~ 24 hours.
More preferably, in step (1), bake out temperature is 50 DEG C, and drying time is 16 hours.
Preferably, the ultraviolet wavelength of step (2) medium ultraviolet light irradiation sterilization is 240 ~ 280nm, and uitraviolet intensity is 60 ~ 100W/cm
2, sterilizing time is 40 ~ 80 minutes.
More preferably, step (2) medium ultraviolet wavelength is 260nm, and uitraviolet intensity is 70 W/cm
2, sterilizing time is 60 minutes.
In step (3), powder diameter is 40 ~ 60 orders.
Beneficial effect of the present invention is: the Chinese crude drug with Cortex Acanthopancis, Fructus Chaenomelis, Radix Et Rhizoma Nardostachyos, Radix Stephaniae Tetrandrae, Rhizoma Atractylodis, Testa dolichoris, Semen Trigonellae etc. with expelling wind and removing dampness, be equipped with Pericarpium Arecae, Semen Pruni etc. again and there is the Chinese medicine adjustments such as consumer edema, finally be aided with the removing toxic substances disinsection efficiency of Semen Coicis, Semen Phaseoli and Semen Arecae, both there is clearing away heat-damp and promoting diuresis effect, there is again the effect of removing toxic substances parasite killing, thus can fundamentally eradicate beriberi and recurrence, and drug effect is gentle, to foot's skin zero damage.And this powder preparation technology is simple, be applicable to large-scale production.
Detailed description of the invention
Below the specific embodiment of the present invention is described in detail.
Embodiment 1
(1), take Pericarpium Arecae 7 parts, Cortex Acanthopancis 7 parts, Fructus Chaenomelis 8 parts, Radix Et Rhizoma Nardostachyos 5 parts, Radix Stephaniae Tetrandrae 6 parts, Fructus Evodiae 3 parts, Rhizoma Atractylodis 6 parts, Semen Phaseoli 20 parts, Semen Pruni 8 parts, Testa dolichoris 8 parts, Semen Trigonellae 6 parts, Semen Arecae 6 parts, Semen Coicis 20 parts and dry 20 hours at 40 DEG C, for subsequent use;
(2), the raw material of drying in step (1) is placed on uviol lamp under, select 260nm ultraviolet wavelength, exposure rate is 70 W/cm
2, sterilizing time is 60 minutes, for subsequent use.
(3), by after the complete raw material of sterilization is fully uniformly mixed in step (2), throw in batches and carry out pulverizing to obtain powder body to pulverizer, cross 60 mesh sieves, collect powder body, divided dose packs, specification: 20g/ wraps.
Using method: powder one bag getting above-mentioned treatment beriberi, down in the warm water of 5L, water temperature is 35 ~ 40 DEG C, after stirring, foot bath 20 minutes.Within seven days, be a course for the treatment of, general 2 ~ 3 courses for the treatment of can fully recover, and never recommit.
Embodiment 2
(1), take Pericarpium Arecae 8 parts, Cortex Acanthopancis 8 parts, Fructus Chaenomelis 9 parts, Radix Et Rhizoma Nardostachyos 6 parts, Radix Stephaniae Tetrandrae 7 parts, Fructus Evodiae 5 parts, Rhizoma Atractylodis 7 parts, Semen Phaseoli 22 parts, Semen Pruni 9 parts, Testa dolichoris 9 parts, Semen Trigonellae 7 parts, Semen Arecae 7 parts, Semen Coicis 22 parts and dry 20 hours at 40 DEG C, for subsequent use;
(2), the raw material of drying in step (1) is placed on uviol lamp under, select 250nm ultraviolet wavelength, exposure rate is 80 W/cm
2, sterilizing time is 70 minutes, for subsequent use.
(3), by after the complete raw material of sterilization is fully uniformly mixed in step (2), throw in batches and carry out pulverizing to obtain powder body to pulverizer, cross 60 mesh sieves, collect powder body, divided dose packs, specification: 20g/ wraps.
Using method is with embodiment 1.
Embodiment 3
(1), take Pericarpium Arecae 9 parts, Cortex Acanthopancis 9 parts, Fructus Chaenomelis 9 parts, Radix Et Rhizoma Nardostachyos 6 parts, Radix Stephaniae Tetrandrae 8 parts, Fructus Evodiae 4 parts, Rhizoma Atractylodis 8 parts, Semen Phaseoli 25 parts, Semen Pruni 9 parts, Testa dolichoris 9 parts, Semen Trigonellae 8 parts, Semen Arecae 9 parts, Semen Coicis 25 parts and dry 24 hours at 40 DEG C, for subsequent use;
(2), the raw material of drying in step (1) is placed on uviol lamp under, select 270nm ultraviolet wavelength, exposure rate is 90 W/cm
2, sterilizing time is 80 minutes, for subsequent use.
(3), by after the complete raw material of sterilization is fully uniformly mixed in step (2), throw in batches and carry out pulverizing to obtain powder body to pulverizer, cross 60 mesh sieves, collect powder body, divided dose packs, specification: 20g/ wraps.
Using method is with embodiment 1.
Embodiment 4
(1), take Pericarpium Arecae 6 parts, Cortex Acanthopancis 6 parts, Fructus Chaenomelis 7 parts, Radix Et Rhizoma Nardostachyos 4 parts, Radix Stephaniae Tetrandrae 5 parts, Fructus Evodiae 2 parts, Rhizoma Atractylodis 5 parts, Semen Phaseoli 18 parts, Semen Pruni 7 parts, Testa dolichoris 7 parts, Semen Trigonellae 5 parts, Semen Arecae 5 parts, Semen Coicis 18 parts and dry 22 hours at 40 DEG C, for subsequent use;
(2), the raw material of drying in step (1) is placed on uviol lamp under, select 240nm ultraviolet wavelength, exposure rate is 60 W/cm
2, sterilizing time is 40 minutes, for subsequent use.
(3), by after the complete raw material of sterilization is fully uniformly mixed in step (2), throw in batches and carry out pulverizing to obtain powder body to pulverizer, cross 40 mesh sieves, collect powder body, divided dose packs, specification: 20g/ wraps
Using method is with embodiment 1.
Embodiment 5
(1), take Pericarpium Arecae 5 parts, Cortex Acanthopancis 5 parts, Fructus Chaenomelis 6 parts, Radix Et Rhizoma Nardostachyos 3 parts, Radix Stephaniae Tetrandrae 4 parts, Fructus Evodiae 1 part, Rhizoma Atractylodis 4 parts, Semen Phaseoli 15 parts, Semen Pruni 6 parts, Testa dolichoris 6 parts, Semen Trigonellae 4 parts, Semen Arecae 3 parts, Semen Coicis 15 parts and dry 18 hours at 40 DEG C, for subsequent use;
(2), the raw material of drying in step (1) is placed on uviol lamp under, select 280nm ultraviolet wavelength, exposure rate is 100 W/cm
2, sterilizing time is 80 minutes, for subsequent use.
(3), by after the complete raw material of sterilization is fully uniformly mixed in step (2), throw in batches and carry out pulverizing to obtain powder body to pulverizer, cross 40 mesh sieves, collect powder body, divided dose packs, specification: 20g/ wraps
Using method is with embodiment 1.
Powder the trying out by people more than 120 for the treatment of beriberi of the present invention, wherein man 80 people, woman 40 people, less than 20 years old 10,21 ~ 30 years old 30 example, 31 ~ 40 years old 25 profit, 41 ~ 50 years old 25 example, 51 ~ 60 years old 20 example, more than 60 years old 10 is routine; Minimum 15 years old of age, maximum 77 years old.Wherein finally 90 example, cure rate reaches 75%; Take a turn for the better 25 examples, improvement rate 20.8%; Invalid 5 examples, inefficiency 4.1%; Total effective rate reaches 95.8%.
Model case:
(1) single ××, man, 22 years old, when seeing a doctor, toe was itched bitterly, cracking, heavy with moistures; When treatment, adopt above-mentioned important powder foot bath, foot bath is after 14 days, and toe heals, and foot bath is after 20 days, and foot's colour of skin is normal, and toe is smooth, to therapeutic effect very satisfaction.
(2) open ××, female, 43 years old, when seeing a doctor, toe is itched bitterly, cracking, and sole has blister; When treatment, adopt above-mentioned important powder foot bath, foot bath is after 16 days, and toe heals, and blister disappears, and foot bath is after 21 days, and thoroughly not bitterly, foot's colour of skin is normal, and toe is smooth, to therapeutic effect very satisfaction.
Although embodiment of the present invention are open as above, but it is not restricted to listed in description and embodiment utilization, it can be applied to various applicable the field of the invention completely, for those skilled in the art, can easily realize other amendment, therefore do not deviating under the general concept that claim and equivalency range limit, the present invention is not limited to specific details.
Claims (9)
1. treat the powder of beriberi for one kind, it is characterized in that, by weight, following component is comprised: Pericarpium Arecae 4 ~ 9 parts, Cortex Acanthopancis 4 ~ 9 parts, Fructus Chaenomelis 6 ~ 9 parts, Radix Et Rhizoma Nardostachyos 3 ~ 6 parts, Radix Stephaniae Tetrandrae 4 ~ 9 parts, Fructus Evodiae 1 ~ 5 part, Rhizoma Atractylodis 3 ~ 9 parts, Semen Phaseoli 9 ~ 30 parts, Semen Pruni 6 ~ 9 parts, Testa dolichoris 6 ~ 9 parts, Semen Trigonellae 4 ~ 9 parts, Semen Arecae 3 ~ 9 parts, Semen Coicis 9 ~ 30 parts.
2. a kind of powder for the treatment of beriberi according to claim 1, it is characterized in that, by weight, following component is comprised: Pericarpium Arecae 5 ~ 8 parts, Cortex Acanthopancis 5 ~ 8 parts, Fructus Chaenomelis 7 ~ 9 parts, Radix Et Rhizoma Nardostachyos 4 ~ 6 parts, Radix Stephaniae Tetrandrae 4 ~ 8 parts, Fructus Evodiae 2 ~ 4 parts, Rhizoma Atractylodis 4 ~ 8 parts, Semen Phaseoli 10 ~ 25 parts, Semen Pruni 7 ~ 9 parts, Testa dolichoris 7 ~ 9 parts, Semen Trigonellae 5 ~ 8 parts, Semen Arecae 4 ~ 8 parts, Semen Coicis 10 ~ 25 parts.
3. a kind of powder for the treatment of beriberi according to claim 2, it is characterized in that, by weight, following component is comprised: Pericarpium Arecae 7 parts, Cortex Acanthopancis 7 parts, Fructus Chaenomelis 8 parts, Radix Et Rhizoma Nardostachyos 5 parts, Radix Stephaniae Tetrandrae 6 parts, Fructus Evodiae 3 parts, Rhizoma Atractylodis 6 parts, Semen Phaseoli 20 parts, Semen Pruni 8 parts, Testa dolichoris 8 parts, Semen Trigonellae 6 parts, Semen Arecae 6 parts, Semen Coicis 20 parts.
4. treat a preparation method for the powder of beriberi described in any one of claim 1 ~ 3, it is characterized in that, comprise the steps:
(1) Pericarpium Arecae, Cortex Acanthopancis, Fructus Chaenomelis, Radix Et Rhizoma Nardostachyos, Radix Stephaniae Tetrandrae, Fructus Evodiae, Rhizoma Atractylodis, Semen Phaseoli, Semen Pruni, Testa dolichoris, Semen Trigonellae, Semen Arecae, Semen Coicis is taken, by weight, dry for standby;
(2) raw material irradiation-sterilize under uviol lamp of, being prepared by step (1);
(3), by raw material prepared by step (2) be fully uniformly mixed, be ground into powder body, sieve through pulverizer, collect powder body, divided dose packs.
5. a kind of preparation method for the treatment of the powder of beriberi according to claim 4, is characterized in that, the bake out temperature of step (1) is 40 ~ 60 DEG C, and drying time is 12 ~ 24 hours.
6. a kind of preparation method for the treatment of the powder of beriberi according to claim 5, is characterized in that, in step (1), bake out temperature is 50 DEG C, and drying time is 16 hours.
7. a kind of preparation method for the treatment of the powder of beriberi according to claim 4, is characterized in that, step (2) medium ultraviolet germicidal wavelength is 240 ~ 280nm, and uitraviolet intensity is 60 ~ 100W/cm
2, sterilizing time is 40 ~ 80 minutes.
8. a kind of preparation method for the treatment of the powder of beriberi according to claim 7, is characterized in that, step (2) medium ultraviolet germicidal wavelength is 260nm, and uitraviolet intensity is 70W/cm
2, sterilizing time is 60 minutes.
9. a kind of preparation method for the treatment of the powder of beriberi according to claim 4, is characterized in that, in step (3), diameter of particle is 40 ~ 60 orders.
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Application publication date: 20150107 |