CN104257848A - Traditional Chinese medicine for treating hepatic ascites - Google Patents

Traditional Chinese medicine for treating hepatic ascites Download PDF

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CN104257848A
CN104257848A CN201410473164.6A CN201410473164A CN104257848A CN 104257848 A CN104257848 A CN 104257848A CN 201410473164 A CN201410473164 A CN 201410473164A CN 104257848 A CN104257848 A CN 104257848A
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parts
chinese medicine
radix
hepatic ascites
treatment
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赵金芝
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/344—Codonopsis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/68—Plantaginaceae (Plantain Family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a traditional Chinese medicine for treating hepatic ascites. According to the adopted technical scheme, the traditional Chinese medicine is prepared from the following medicinal raw materials in parts by weight: 5-15 parts of veronicastrum herb, 15-25 parts of semen plantaginis, 25-35 parts of bighead atractylodes rhizome, 5-15 parts of kanziol, 5-15 parts of lysimachia christinae hance, 25-35 parts of codonopsis pilosula and 15-25 parts of rhizoma nardostachyos. The traditional Chinese medicine disclosed by the invention is low in toxic and side effect, and has a curative effect on hepatic ascites and has low cost.

Description

A kind of Chinese medicine for the treatment of hepatic ascites
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of Chinese medicine for the treatment of hepatic ascites particularly.
Background technology
Liver is the most important metabolism organ of human body.Cirrhotic ascites is commonly called as hepatic ascites.Normal person's intraperitoneal has a small amount of free ascites, is generally about 50 milliliters, plays and maintains lubrication between internal organs, when too much free fluid appears in intraperitoneal, be called ascites.Cirrhotic ascites is a kind of chronic hepatopathy, once ascites produces, illustrates that the function of liver self is very poor.The hepatic ascites harm of late period to human body is very large, so hepatic ascites patient must treat in time.
Current China treatment hepatic ascites mainly adopts western medical treatment, and doctor trained in Western medicine, while treatment hepatic ascites, can be brought very large side effect, as Drug therapy, mainly comprise diuretic, vasoactive agent and albumin etc.But usually there is many drawbacks, diuresis can cause hypokalemia in body repeatedly, easily excites alkalosis, thus brings out hepatic encephalopathy etc.Also have and adopt the treatment that taps the abdomen, although can very fast having effect, the harm of drawing water be inevitable.Draw water and easily cause infection, form peritonitis, draw water and can lose albumin in a large number, easily cause hepatic coma, albumin must be supplemented in a large number, but albumin is expensive, therefore can cause certain financial burden to patient; And treatment of drawing water needs repeatedly to carry out, and easily recur.
Summary of the invention
In order to overcome the above problems, the invention provides a kind of toxic and side effects little, to hepatic ascites, there is curative effect, the Chinese medicine that cost is low.
The technical solution used in the present invention is: a kind of Chinese medicine for the treatment of hepatic ascites, is made up of following raw material medicaments in part by weight proportioning:
Herba veronicastri villosuli 5 ~ 15 parts, Semen Plantaginis 15 ~ 25 parts, the Rhizoma Atractylodis Macrocephalae 25 ~ 35 parts, Radix Kansui 5 ~ 15 parts,
Herba Lysimachiae 5 ~ 15 parts, Radix Codonopsis 25 ~ 35 parts, Radix Et Rhizoma Nardostachyos 15 ~ 25 parts.
Preferably, the Chinese medicine of above-mentioned treatment hepatic ascites, be made up of following raw material medicaments in part by weight proportioning:
Herba veronicastri villosuli 10 parts, Semen Plantaginis 20 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, Radix Kansui 10 parts,
Herba Lysimachiae 10 parts, Radix Codonopsis 30 parts, Radix Et Rhizoma Nardostachyos 20 parts.
The Chinese medicine of above-mentioned treatment hepatic ascites, described Radix Kansui is stir-baked RADIX KANSUI with vinegar.Its concocting method is: get clean Radix Kansui, mix thoroughly with vinegar, puts in pot and fries to micro-dry with slow fire, take out and dry (every Radix Kansui 100 jin, with vinegar 30 ~ 50 jin).
The Chinese medicine of above-mentioned treatment hepatic ascites, grinds each crude drug, mix homogeneously, makes oral formulations.Described oral formulations is powder, capsule, tablet, electuary and pill.
In the present invention,
Herba veronicastri villosuli: [nature and flavor] bitter in the mouth; Cold nature [return through] returns liver; Spleen; Kidney channel [function cures mainly] row water; Detumescence; Dissipating blood stasis; Removing toxic substances.Main cirrhotic ascites; Oedema due to nephritis; Traumatic injury; Skin ulcer swells furunculosis; Scald; Venom.
Semen Plantaginis: [nature and flavor] sweet in the mouth; Light; Cold nature [return through] returns lung; Liver; Kidney; Urinary bladder channel [function cures mainly] clearing away heat and promoting diuresis; Eliminating dampness by diuresis antidiarrheal; Improving eyesight; Eliminate the phlegm.Main dysuria; Stranguria with turbid discharge leukorrhagia; Edema distension; Heat-damp in summer dysentery; Conjunctival congestion is hidden from view; Expectorant heat syndrome cough is breathed heavily.
The Rhizoma Atractylodis Macrocephalae: [nature and flavor] bitter in the mouth; Sweet; [return through] warm in nature returns spleen; Stomach is through [function cures mainly] invigorating the spleen and benefiting QI; Dampness diuretic; Hidroschesis; Antiabortive.Main deficiency-weakness of spleen-QI; Spiritlessness and weakness; The few abdominal distention of lack of appetite; Large loose stool is thin; Fluid-retention stagnating in the interior; Dysuria; Edema; Dizziness due to fluid-retention; Temperature numbness is ached; Spontaneous sweating due to deficiency of QI; Frequent fetal movement.
Radix Kansui: [nature and flavor] bitter in the mouth; Cold in nature; Poisonous [return through] spleen; Lung; Kidney; Bladder; Large intestine; Small intestine meridian [function cures mainly] removing fluid-retention by purgation; Removing mass relieving constipation.Main edema; Ascites; Prolonged fluid-retention blocked-up chest; Epilepsy; Breath with cough; Sphincter disturbance.
Herba Lysimachiae: [nature and flavor] are sweet; Micro-hardship; [return through] cool in nature liver; Gallbladder; Kidney; Urinary bladder channel [function cures mainly] relieving stranguria by diuresis; Heat-clearing and toxic substances removing; Dissipating blood stasis for subsidence of swelling.Main liver and gall and urinary system calculus; Pyretic stranguria; Oedema due to nephritis; Jaundice due to damp-heat; Sore carbuncle; Venom; Traumatic injury.
Radix Codonopsis: [nature and flavor] sweet in the mouth; Property flat [return through] return spleen; Lung meridian [function cures mainly] strengthening the spleen and tonifying the lung, supplementing QI for promoting the production of body fluid.Main weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung are breathed with cough, spontaneous perspiration of breathing hard, feeble QI two lose all cards.
Radix Et Rhizoma Nardostachyos: [nature and flavor] acrid in the mouth; Sweet; [return through] warm in nature returns spleen; Stomach is through [function cures mainly] regulating QI to relieve pain; Activating spleen and strengthening stomach.Main abdominal distention; Not national diet; Toothache; Beriberi.
Clinical treatment observation of the present invention is as follows:
(1) physical data
Patient 180 example, wherein male 101 example, women 79 example.
(2) diagnostic criteria:
There is jaundice, hematemesis and melena phenomenon in patient; Patient's abdominal tympanites, stomach wall are tightened shinny; Patient's appetite obviously goes down, and namely feels epigastric discomfort and glutted after feed, feels sick; Weak.
(3) Therapeutic Method
Get Herba veronicastri villosuli 9-11g, Semen Plantaginis 18-22g, Rhizoma Atractylodis Macrocephalae 28-32g, stir-baked RADIX KANSUI with vinegar 8-12g, Herba Lysimachiae 8-12g, Radix Codonopsis 28-32g, Radix Et Rhizoma Nardostachyos 18-22g, grind to form fine powder, mix homogeneously, make powder, be divided into 10 parts, every day, early (medicine) being taken before meal was a, within 30 days, was a course for the treatment of, took two courses for the treatment of continuously.
(4) efficacy assessment standard
Cure: jaundice, hematemesis and melena phenomenon disappear; Abdominal part recovers normal condition; Appetite increases; Antisecosis.
Take a turn for the better: jaundice, hematemesis and melena phenomenon disappear; Patient's abdominal tympanites reduces; Appetite increases; Antisecosis.
Invalid: jaundice, hematemesis and melena phenomenon are without improvement; Abdominal tympanites, stomach wall tighten shinny phenomenon without improvement; Without appetite, feel sick; Weak.
(5) therapeutic outcome
After two course of therapy, cure 125 people, take a turn for the better 40 people, invalid 15 people.
The present invention adopts the synergism of 7 taste Chinese medicines, and after taking two courses for the treatment of, cure rate reaches 69.44%, and improvement rate reaches 22.22%, and inefficiency is only 8.33%.
Detailed description of the invention
Embodiment 1
(1) treat a Chinese medicine for hepatic ascites, be made up of following raw material medicaments in part by weight proportioning:
Herba veronicastri villosuli 10g, Semen Plantaginis 20g, Rhizoma Atractylodis Macrocephalae 30g, stir-baked RADIX KANSUI with vinegar 10g, Herba Lysimachiae 10g, Radix Codonopsis 30g, Radix Et Rhizoma Nardostachyos 20g.
(2) preparation method
Stir-baked RADIX KANSUI with vinegar concocting method is: get clean Radix Kansui, mix thoroughly with vinegar, puts in pot and fries to micro-dry with slow fire, take out and dry (every Radix Kansui 100 jin, with vinegar 30 ~ 50 jin).
By above-mentioned crude drug, grind to form fine powder, mix homogeneously, make powder, be divided into 10 parts, each serving with portion.
Embodiment 2
(1) treat a Chinese medicine for hepatic ascites, be made up of following raw material medicaments in part by weight proportioning:
Herba veronicastri villosuli 5g, Semen Plantaginis 25g, Rhizoma Atractylodis Macrocephalae 25g, stir-baked RADIX KANSUI with vinegar 5g, Herba Lysimachiae 15g, Radix Codonopsis 25g, Radix Et Rhizoma Nardostachyos 15g.
(2) preparation method
By above-mentioned crude drug, grind to form fine powder, mix homogeneously, be divided into 10 parts, routinely technique, make capsule preparations, each serving with one.
Embodiment 3
(1) treat a Chinese medicine for hepatic ascites, be made up of following raw material medicaments in part by weight proportioning:
Herba veronicastri villosuli 15g, Semen Plantaginis 15g, Rhizoma Atractylodis Macrocephalae 35g, stir-baked RADIX KANSUI with vinegar 15g, Herba Lysimachiae 5g, Radix Codonopsis 35g, Radix Et Rhizoma Nardostachyos 25g.
(2) preparation method
By above-mentioned crude drug, grind to form fine powder, mix homogeneously, be divided into 10 parts, routinely technique, make pill, each serving using a ball.

Claims (5)

1. treat a Chinese medicine for hepatic ascites, it is characterized in that being made up of following raw material medicaments in part by weight proportioning:
Herba veronicastri villosuli 5 ~ 15 parts, Semen Plantaginis 15 ~ 25 parts, the Rhizoma Atractylodis Macrocephalae 25 ~ 35 parts, Radix Kansui 5 ~ 15 parts,
Herba Lysimachiae 5 ~ 15 parts, Radix Codonopsis 25 ~ 35 parts, Radix Et Rhizoma Nardostachyos 15 ~ 25 parts.
2. the Chinese medicine for the treatment of hepatic ascites as claimed in claim 1, is characterized in that being made up of following raw material medicaments in part by weight proportioning:
Herba veronicastri villosuli 10 parts, Semen Plantaginis 20 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, Radix Kansui 10 parts,
Herba Lysimachiae 10 parts, Radix Codonopsis 30 parts, Radix Et Rhizoma Nardostachyos 20 parts.
3. the Chinese medicine for the treatment of hepatic ascites as claimed in claim 1 or 2, is characterized in that described Radix Kansui is stir-baked RADIX KANSUI with vinegar.
4. the Chinese medicine for the treatment of hepatic ascites as claimed in claim 1 or 2, it is characterized in that each crude drug to grind, mix homogeneously, makes oral formulations.
5. the Chinese medicine for the treatment of hepatic ascites as claimed in claim 4, is characterized in that described oral formulations is powder, capsule, tablet, electuary and pill.
CN201410473164.6A 2014-09-16 2014-09-16 Traditional Chinese medicine for treating hepatic ascites Pending CN104257848A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1211444A (en) * 1998-09-22 1999-03-24 龚晓东 Chinese medicinal powder preparation for treating hepatocirrhosis
CN1698751A (en) * 2005-04-29 2005-11-23 姜德连 Chinese medicinal powder preparation for treating hepatic ascites
CN101757541A (en) * 2009-11-05 2010-06-30 泰一和浦（北京）中医药研究院有限公司 Traditional Chinese medicine composition for treating liver ascites symptoms and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1211444A (en) * 1998-09-22 1999-03-24 龚晓东 Chinese medicinal powder preparation for treating hepatocirrhosis
CN1698751A (en) * 2005-04-29 2005-11-23 姜德连 Chinese medicinal powder preparation for treating hepatic ascites
CN101757541A (en) * 2009-11-05 2010-06-30 泰一和浦（北京）中医药研究院有限公司 Traditional Chinese medicine composition for treating liver ascites symptoms and preparation method thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
李宏红等: "《苓桂术甘汤》", 31 January 2013, 中国医药科技出版社 *
赵焕霞等: "薄层扫描法测定7种腹水草属植物中熊果甙的含量", 《中国野生植物资源》 *
黄亚博: "肝硬变腹水的中医药研究态势述评", 《中医药学刊》 *

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