CN104256629A - Total nutrient formulation food for uterine cancer - Google Patents

Total nutrient formulation food for uterine cancer Download PDF

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Publication number
CN104256629A
CN104256629A CN201410575369.5A CN201410575369A CN104256629A CN 104256629 A CN104256629 A CN 104256629A CN 201410575369 A CN201410575369 A CN 201410575369A CN 104256629 A CN104256629 A CN 104256629A
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vitamin
radix
cancer
food
uterus
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胡安然
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A—HUMAN NECESSITIES
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    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
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    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
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    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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Abstract

The invention provides a total nutrient formulation food, a specific total nutrient formulation food or a non-total nutrient formulation food for patients suffering from a uterine cancer to eat. Based on the requirements in 'general rule of formula food for special medical use', the formula is formed by crushing and mixing a variety of extract essence extracted from edible and medicinal traditional Chinese medicine with a prehydrolysis SBE technology and a variety of microencapsulated probiotics as well as biological enzymolysis extraction-based oligopeptide, prebiotics, amino acid, carbohydrate, multivitamins and mineral substances in combination with body characters of the patients suffering from the uterine cancer, which can not only be used as a single nutrient source to meet nutritional requirements of the patients suffering from the uterine cancer, but also has the effects of calming the liver and clearing heat, replenishing qi to invigorate the spleen, staunching bleeding by astriction, activating blood and dissolving stasis, regulating qi to alleviate pain, nourishing yin and kidney, and enhancing the immunity.

Description

The full nutritional formulas of the cancer of the uterus
Technical field
The invention belongs to integration of drinking and medicinal herbs class formula and food technology field, specifically the Traditional Chinese Medicine marrow of " Chinese medicine of integration of drinking and medicinal herbs " is theoretical and " multiple probio " combines, and adds the full nutritional formulas of the cancer of the uterus, specific full nutritional formulas or the non-fully nutritional formulas made for auxiliary material with small peptide, prebiotics, amino acid, carbohydrate, B B-complex, composite mineral matter.
Background technology
Usually the cancer of the uterus is made in fact to refer to carcinoma of endometrium, it occurs in uterus internal layer, it is cancer common in female reproductive system, to be number four in the modal cancer of women position, be more common in the women of 50 ~ 60 years old, post menopausal of being everlasting occurs, and the incidence of disease is worldwide in rising trend in recent years, many positions of health can be transferred to: be diffused into canal of uterine cervix downwards from uterus, be upwards diffused into ovary from fallopian tubal; Also periuterine tissue can be infiltrated; Or transfer to the position away from uterus by lymphatic system and blood circulation, the disorderly women of early marriage, early childbirth, fecund and sexual life has higher illness rate, also have at present and think that the cholesterol in smegma can change carcinogen into after bacterial action, also be the major incentive causing cervical carcinoma, the contingent reason of the cancer of the uterus has: 1. sexual life: if women has the male partner of more than 2, suffer from the probability of the cancer of the uterus and have significant increase especially, the 2. age: within 35 ~ 45 years old, be the cancer of the uterus send out the age well; 3. venereal disease infection: the infection of venereal disease, representative life is more complicated usually, and the relative probability suffering from the cancer of the uterus also can be higher; 4. cervix inflammation: if having long-term Cervical damage, broken skin, erosion, inflammation, all may change early stage uterine cancer cells into; 5. smoking: smoking can increase the chance suffering from the cancer of the uterus: one for smoking can reduce body immunity and make uterine cancer cells accelerated development, another is the development that smoking itself produces some materials and likely causes uterine cancer cells; 6. estrogen, some scholar thinks that lutern can change the stability of cervical epithelial cell, and abnormal change easily occurs, and likely causes the development of uterine cancer cells;
The cancer of the uterus adopts the mode of parenteral nutrition (namely inputting nutritional drugs) to carry out nutritional supplementation to cancer patient clinically more, and long-term parenteral nutrition supplements and easily causes enteron aisle Villus atrophy, and accompanying infection, thus increases the weight of the harm to body; " integration of drinking and medicinal herbs " is to one of contribution of mankind's most worthy among Chinese original medical science; The traditional Chinese medical science is always emphasized " medication not as dietotherapy ", dietotherapy become modern pursue recover one's original simplicity, the optimal selection of health diet; Allow people dispel slight illness in the process enjoying cuisines, avoid and have an injection, take medicine, even pain of surgery.
For food of special nutrients, there are corresponding regulation and Application and Development in the developed country such as the U.S., European Union; And the full nutritional formulas of wholefood clear stipulaties: 2.1.1 in China GB29922-2013 " special medicine purposes formula food general rule " national food safety standard: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need; 2.1.2 specific full nutritional formulas: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need under specified disease or medical condition.
Traditional Chinese medical science traditional medicine is thought: " spleen (i.e. digestive system) is the foundation of acquired constitution ", and stomach health is healthy basis, and 99% of human nutrition needs by intestinal absorption, and intestinal bowel disease is also the source of ten thousand diseases; But along with the age is larger, in enteron aisle, profitable strain (probio) ratio reduces gradually; As Bifidobacterium Bifidum accounts for 98% infant period, be down to 10% to during the middle age, within 65 years old, only account for 5% later; People is older, and probio is fewer, and function of intestinal canal also declines thereupon gradually, more and more studies display, normal flora human consumption, immunity and disease-resistant etc. in have many irreplaceable effects; The change of gut flora composition and the generation of various diseases, particularly intestines problem develop closely related, and find from existing clinical research: probio can play regulating intestinal canal flora, controls intestinal inflammatory effect, is that one intervenes control method safely and effectively.
Though direct probiotic oral has certain effect, but due to probio one cannot field planting in enteron aisle, and stop, occupy-place is little, easily run off, withdraw rear harmful bacteria and easily recur, associated patient needs long-term taking, and treatment cycle is long, often uses afterwards that recurrence rate is very high, for shortening the treatment cycle of associated patient, recurrence rate after minimizing drug withdrawal, this team is by studying the key technology of probio field planting mechanism in enteron aisle over nearly 3 year, make great efforts " Chinese medicine of the integration of drinking and medicinal herbs " compound seeking to improve probio field planting in enteron aisle, consider several key elements of probio field planting in enteron aisle: the existence of prebiotics can play field planting effect, the reduction of intestinal pH environment and the enteron aisle adhesive capacity etc. of raising probiotic cell, based on above-mentioned key element, suitable food materials screen from tens of kinds " Chinese medicines of integration of drinking and medicinal herbs " in this seminar, Late Cambrian interpolation Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, the extract of the traditional Chinese medicine ingredients of the integration of drinking and medicinal herbs such as Gorgon fruit and jerusalem artichoke and stachyose, yeast, after Glu etc., very strong field planting effect is had to external source probio, prescription for probio in enteral microecological formulation is selected to provide experimental basis.
Favourable is in the market primary raw material in order to eat source property small peptide, add the mushroom of medicine-food two-purpose, dried orange peel, matrimony vine, Chinese yam, Poria cocos, the extract of sealwort etc., B B-complex and mineral matter composition compound prescription, utilize the product that probio is primary raw material in addition, but also do not find the constitutive character in conjunction with cancer of the uterus patient, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility is with the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials is the full nutritional formulas that auxiliary material is made, specific full nutritional formulas or similar products.
goal of the invention
The object of the invention is on the theoretical treatment method of succession traditional Chinese medical science marrow, the probio of multiple raising cancer of the uterus patient immunity and the extract of " Chinese medicine of integration of drinking and medicinal herbs " compound combine by initiative, add with small peptide, amino acid, carbohydrate, multivitamin, several mineral materials is auxiliary material, the cancer of the uterus patient institute essential nutrients of hypoimmunity can not only be supplemented, improve body nutrition condition, can also and utilize function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function, probio can play regulating intestinal canal flora, toxic and side effect is little, safe and effective, and the full nutritional formulas of the acceptable applicable cancer of the uterus edible for patients of people, specific full nutritional formulas or non-fully nutritional formulas.
summary of the invention:
This R&D team is according to the requirement of " special medicine purposes formula food general rule ", the constitutive character of the cancer of the uterus patient that binding immunoassay power is low, the advanced physiology of comprehensive nowadays American Harvard University, medicine, the achievement in research such as nutrition and clinical practice, according to " the middle residence that disappears benefit ", marrow theory (the liver of the Traditional Chinese Medicine of " equilibrium is taken good care of ", spleen, kidney three is dirty with being adjusted to main principle), adopt the Chinese medical extract elite of more than 4 kinds medicine-food two-purposes, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin and mineral matter auxiliary material, not only can be used as the nutritional need that single source of nutrition meets cancer of the uterus patient, also has calming liver and clearing heat, replenish qi to invigorate the spleen, astringing for hemostasis.Blood circulation promoting competent silt, regulating qi-flowing for relieving pain, the full nutritional formulas of educating effect of cloudy nourshing kidney and develop immunitypty, specific full nutritional formulas or non-fully nutritional formulas (compound prescription be combined into).
1, the main component of the present invention's formula is:
Chinese medical extract is dirty with being adjusted to main principle from the liver,spleen,kidney three theory of traditional Chinese medical science according to the constitutive character of cancer of the uterus patient, utilize the function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function to build up resistance, and choose following several large class medicine and carry out compatibility; Wherein: the stem of noble dendrobium, reinforcing stomach reg fluid is nourishing Yin and clearing heat; Motherwort, invigorates blood circulation, silt of dispelling, menstruation regulating, disappears water; The fruit of glossy privet, tonifies the liver and kidney, clearind deficient heat, strong waist knee, improve visual and auditory acuity, black beard and hair; The Radix Astragali, it has enhanced machine body immunity function, protects the liver, diuresis, anti-ageing, resisting stress, step-down and antibacterial action more widely; Radix bupleuri, in having and inducing sweat, soothing the liver, rise effect of sun; The bighead atractylodes rhizome, has strengthening the spleen and replenishing qi, eliminating dampness Li Shui, hidroschesis, antiabortive effect; Radix Angelicae Sinensis, benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes laxation; Rattletop, rises sun, delivers, promoting eruption, removing toxic substances; Tarragon, has warming channel for arresting bleeding, eliminating cold to stop pain, effect of antiabortive, wet down desinsection; Safflower, activating blood to promote menstruation, blood stasis removing analgesic; Ligusticum wallichii, has blood-activating and qi-promoting, effect of wind-expelling pain-stopping; The radix paeoniae rubrathe, the row stasis of blood, pain relieving, cool blood, detumescence; Carbonized hair, has effect of astringing to arrest bleeding, stagnation resolvation diuresis; Edible tulip has clearing heat and detoxicating, the effect of the carbuncle that disappears dissipating bind; Selfheal, has the effect of improving eyesight of relieving inflammation or internal heat, and can control red eye, swell pain, headache etc.; Cordyceps militaris, can regulate whole body function, improves immunocompetence, strengthen the phagocytic function of macrophage, the formation of enhancing antibody; Donkey-hide gelatin, enriching yin of enriching blood, moisturizes, hemostasis; Poria cocos, has the function of clearing damp and promoting diuresis, beneficial spleen and stomach, antitoxic heart-soothing and sedative; The root of Dahurain angelica, function expels pathogenic wind from the body surface, eliminating cold to stop pain, dehumidifying are sensible, detumescence and apocenosis; Ginseng, tonifying Qi emergency treatment of collapse, beneficial blood multiple arteries and veins, mental-tranquilization, promote the production of body fluid to quench thirst, tonifying lung Dingchuan, invigorating the spleen to arrest diarrhea, holder poison close sore etc.; Peach kernel, the broken blood stasis of blood, moisturizes laxation; Chinese yam, has nourishing strong, aid digestion, holds back abnormal sweating, effect of antidiarrheal; Matrimony vine, the effects such as LBP-X has Promote immunity, anti-ageing, antitumor, scavenging free radicals, antifatigue, radioresistance, protects the liver, reproductive function protection and improvement;
Medicinal and edible Chinese medicine extract of the present invention refers to Cordyceps sinensis (aweto mycelium), the stem of noble dendrobium, lucidum spore powder (broken wall), motherwort, the fruit of glossy privet, the Radix Astragali, radix bupleuri, the bighead atractylodes rhizome, Radix Angelicae Sinensis, the root of herbaceous peony, the root bark of tree peony, rattletop, tarragon, safflower, the dried rhizome of rehmannia, Ligusticum wallichii, the radix paeoniae rubrathe, myrrh, the seed of Chinese dodder, carbonized hair, oldenlandia diffusa, edible tulip, the red sage root, golden cypress, radix scrophulariae, selfheal, Cordyceps militaris, donkey-hide gelatin, Poria cocos, the root of Dahurain angelica, ginseng, peach kernel, Chinese yam, matrimony vine, coix seed, dandelion, Semen Benincasae, sophora flower, Radix et Rhizoma Gynurae divaricatae, peppermint, Radix Glycyrrhizae, mountain Cape jasmine, oyster wherein more than 4 kinds or all, biological enzymolysis or prehydrolysis SBE is adopted to extract and microencapsulation, mixture after spray-dried and cryodesiccated extract.
2, multiple probio: make probio major part can arrive enteron aisle by the strong acid environment of stomach, to promote the propagation of probio, regulate microecological balance in intestines, promote the absorption to trace element, strengthen taste motor function, accelerate the absorption of drug effect, improve the micropopulation of mucous membrane surface or the balance of enzyme, or stimulate body specificity or nonspecific immunity mechanism, improve body colonization resistance or immunity; Xing etc., with Bifidobacterium and Bacillus acidi lactici pretreatment law during ischemia/reperfusion rat, obviously can reduce the level of intestinal endotoxemia and the generation of preventing liver injury; Selective enteron aisle decontamination dye is also the important measures of adjustment intestinal microecology, has research application enteron aisle not absorb rifamycin antibiotic former times bright (rifaximin), by urease-producing in suppression enteron aisle and the growth of producing ammonium bacteria, builds up resistance;
Multiple probio of the present invention all adopts the probio after microencapsulation, except streptococcus thermophilus, wherein Bifidobacterium: refer to that bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum are wherein a kind of, several or all mix; Lactobacillus refers to: lactobacillus acidophilus powder, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, Lactobacillus plantarum, lactobacillus paraceasi, Yue Shi lactobacillus are wherein a kind of, several or all mix.
3, small peptide: be oligopeptide, refer to the small molecule protein utilizing bio-enzyme engineering technology separation and Extraction from animal or vegetable protein, its mean molecule quantity is at below 1000Dalton, soluble in water, to acid, thermally-stabilised, can not need directly to absorb through digestion, bioavailability is high, absorbing and utilizing the amino acid and complete protein that are better than dissociating, can be applicable in Protein intake food, especially for the crowd that abilities of digestive and absorption is low, small peptide is splendid nitrogenous source, except trophic function, small peptide also has a series of physiological active functions: the digestion and absorption function improving small intestine, strengthen immunity of organisms, anti-oxidant, auxiliary adjustment blood sugar, auxiliary adjustment of blood fat, aided blood pressure-lowering, radioresistance, promote mineral absorption, strengthen the action effect of function factor in medicine-food two-purpose Chinese herbal medicine,
Small peptide of the present invention refers to that maize oligopeptide, wheat oligopeptide, marine collagen peptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide are wherein a kind of, several or all mix.
4, prebiotics: with short probio intestinal colonisation, enteron aisle convergence, reduce intestinal pH environment, also do not utilized by most enteron aisle spoilage organisms, but beneficial bacteria in human body can be promoted---the growth and breeding of lactobacillus, Bifidobacterium, thus spoilage organisms can be suppressed to grow, contribute to improving and maintaining enteron aisle normal function; Long-term edible can to delay senility, defaecation, raising immunity, the absorptivity that alleviates burden of liver, improve nutrient, particularly can improve the absorption of body to metal ions such as calcium, iron, zinc; Optionally promote outside the growth and breeding of beneficial bacterium (bifid, lactic acid), also can metabolism be acid product as organic acids such as lactic acid, knot intestinal pH is reduced, suppresses the growth of intestinal harmful bacillus; Water-Electrolyte in small intestine is made to be trapped in enteric cavity, produce and highly ooze effect, stimulate enterocinesia to cause laxative, thus promote the discharge of intestinal endotoxin and other toxicants, lactulose also can directly endotoxin in deactivation enteron aisle, reduce gut pH, extensively model is applied to the treatment of enhancing cancer of the uterus resistance;
Prebiotics of the present invention is 2 classes
A. very strong field planting effect prebiotics is had to external source probio: the extract of Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, jerusalem artichoke, stachyose, yeast wherein several or all mix;
B. common prebiotics: oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix;
Originally oligoisomaltose, stachyose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix is referred to.
5, carbohydrate: carbohydrate is by carbon, hydrogen and oxygen three kinds of element compositions, it is for human body provides nutrient the most cheap in three of heat energy kinds of main nutrients, when taking in sufficient, energy can be provided in time by rapid oxidation in vivo, the protein of preciousness is avoided to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the glycolipid of nerve fiber and the important composition composition of DNA (DNA) conveyed hereditary information, and the glycogen contained in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin that some poisonous chemical substance and various pathogenic microorganisms produce,
Carbohydrate of the present invention refers to Arabinose, fructose, galactolipin, lactose, glucose, maltose, water-soluble dietary fiber, starch, glycogen one wherein, several or all mix.
6. amino acid: be divided into essential amino acid and nonessential amino acid, is the base unit forming protein, gives protein specific molecular morphosis, make it have biochemical activity; Absorb appropriate methionine and contribute to the metabolism of various sulfur-containing compound in human body and the methyl contained by it methylates to Toxic or medicine and plays the effect of removing toxic substances; Leucine can repair muscle, controls blood sugar, and provides energy to bodily tissue, essential amino acid phenylalanine can suppress cancer growth, can reduce again the toxic and side effect of medicine, and lysine can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development; Arginine contributes to changing the ammonia in blood into urea and excreting out; For hyperammonemia, hepatic dysfunction etc. are all powerful; Histidine reduces gastric acidity, relaxes the pain of gastrointestinal procedures, alleviates gestational period vomiting and scorching hot sense, suppresses nervous by vegetative nerve and alimentary canal that is that cause festers, to anaphylactia, as also powerful in asthma etc.; Tryptophan can prevent pellagra, depression, improving water flood and adjustment mood;
Amino acid of the present invention refers to Glu, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix.
7. vitamin and mineral matter:
Vitamin and mineral matter are the nutrients of needed by human, the nutrient of the vitamin added in the present invention to be vitamin and mineral matter be needed by human;
The vitamin added in the present invention is vitamin A, vitamin D, vitamin E, vitamin K, vitamin K1, vitamin C, vitamin B1, vitamin B2, vitamin B6, vitamin B12, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin one wherein, several or all mix;
The mineral matter added in the present invention is calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum one wherein, several or all mix, and mineral matter of the present invention is added to the organic or inorganic compound of this mineral matter;
In the present invention, the addition of vitamin and minerals performs with reference to " special medicine purposes formula food general rule ", now for 1000g finished product, addition is vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g.
8. the present invention is with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology of the industrialization production of formation; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product prevent and treat the cancer of the uterus significantly improves compared with the like product of market.
9. adopt above-mentioned integrated innovation technique various batching to be mixed solid beverage, the granule of making powdery, and be distributed into 10g/ bag, after dissolving with about 150ml warm water (45 degree), directly drink or take in through nasal feeding; Also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require.
The characteristic of this full nutritional formulas of filling a prescription and the following aspects is mainly manifested in the effect of body:
1. the present invention is the requirement according to " special medicine purposes formula food general rule ", in conjunction with the constitutive character of cancer of the uterus patient, the achievement in research developments such as the advanced physiology of comprehensive nowadays American Harvard University, medicine, nutrition and clinical practice, vary with each individual, gold compatibility.
2. the present invention is according to the marrow theory (liver,spleen,kidney three is dirty with being adjusted to main principle) of the Traditional Chinese Medicine of " the middle residence that disappears is mended ", " equilibrium is taken good care of ", the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is adopted to be primary raw material, with prebiotics, carbohydrate, amino acid, multivitamin and mineral matter for auxiliary material, the organic assembling of various batching, various function is merged, and by the synergy between active ingredient, humidification effect.
3. have effective absorbency, utilize formula of the present invention, various component adopts the food of suitable ratio collocation preparation, in isotonic state after a certain amount of water-soluble solution, small intestine can be arrived quickly through stomach, absorb fast, completely, cancer of the uterus patient desired nutritional can be supplemented rapidly.
4. in the present invention's formula, adopt the extract of various medicine-food two-purpose Chinese herbal medicine, containing several functions active component, not only increase the concentration of function factor, reduce the absorption of various impurity, contribute to alleviating liver kidney burden, there is the effect strengthening resistance of human body, also have calming liver and clearing heat, replenish qi to invigorate the spleen, astringing for hemostasis.Blood circulation promoting competent silt, regulating qi-flowing for relieving pain, educates effect of cloudy nourshing kidney and develop immunitypty.
5. probio contained in the present invention's formula, multiple probio can safeguard enteron aisle normal bacteria colony balance, suppress the growth of pathogen, prevent gastrointestinal disorders etc., synthetic vitamin in enteron aisle, amino acid and raising body are to the absorption of calcium ion, strengthen human immunologic function, prevent antibiotic side effect, improve host to the tolerance of radioactive ray, lactobacillus significantly increases intestinal mucosal immune globulin A (SIgA) content, to body intestinal mucosa local immunity, there is regulating action, regulate stomach, intestines Tiny ecosystem, calcium can be improved, phosphorus, the utilization rate of iron, promote the absorption of iron and vitamin D, produce vitamin K and Cobastab, the absorption of cholesterol can also be reduced.
6. formula food of the present invention with the food source property bioactive short peptide in multiple source for nitrogenous source, because small peptide does not need digestion and Absorbable rod, more be conducive to the utilization of body, effectively can improve cancer of the uterus patient negative nitrogen balance, and food source property small peptide can improve the 26S Proteasome Structure and Function of intestinal epithelial cell, improves the absorbability of intestinal mucosa.
7. this prescription have employed this team by over nearly 3 year to the achievement that the key technology of probio field planting mechanism in enteron aisle is studied, improve " Chinese medicine of integration of drinking and medicinal herbs " compound of probio field planting in enteron aisle, the existence combining prebiotics can play the key elements such as field planting effect, the reduction of intestinal pH environment and the enteron aisle adhesive capacity of raising probiotic cell, and therefore the composition of this food formula greatly strengthen the field planting effect to external source probio.
8. prebiotics contained in the present invention's formula; by promoting the growth and breeding of probio in intestines; suppress the growth of spoilage organisms; form one protective barrier at intestinal mucosal surface simultaneously; the damage of enteron aisle spoilage organisms to intestinal mucosa can be resisted; reduce the absorption of intestinal toxic material; intestines peristalsis can also be promoted; accelerate the discharge of residuals in intestines; constipation can be prevented; and by promoting that the growth and breeding of beneficial bacteria of intestinal tract also can strengthen immunity of organisms, the bioactivators such as small peptide, carbohydrate and active polysaccharide have synergy.
9, in the present invention's formula, contained carbohydrate is for human body provides three of heat energy kinds of main nutrients, energy can be provided in time by rapid oxidation in vivo, the protein of preciousness is avoided to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the glycolipid of nerve fiber and the important composition composition of DNA (DNA) conveyed hereditary information, and the glycogen contained in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin that some poisonous chemical substance and various pathogenic microorganisms produce.
10, contained in the present invention's formula amino acid, it is the base unit forming protein, give protein specific molecular morphosis, make it have biochemical activity, contribute to the metabolism of various sulfur-containing compound in human body and the methyl contained by it methylates to Toxic or medicine and plays the effect of removing toxic substances, muscle can be repaired, control blood sugar, and provide energy to bodily tissue, also can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development.
11, formula food of the present invention is containing multivitamin and mineral matter, can supplement rapidly the micronutrient needed for cancer of the uterus patient, small peptide by with the chelating of calcium, iron, zinc etc. after, further increase the absorptivity of mineral matter element.
12, not fatty and cholesterol in the present invention's formula, while supplementary protein, micronutrient, can not increase the absorption of fat, cholesterol, avoid the adverse effect of the high protein diet such as meat, egg.
Detailed description of the invention
Below by following examples, the invention will be further described, and it will contribute to understanding the present invention.
Embodiment one
Realizing the full nutritional formulas of the object of the invention cancer of the uterus is constitutive character in conjunction with cancer of the uterus patient, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with the Chinese medical extract elite of more than 4 kinds medicine-food two-purposes, multiple probio, small peptide for primary raw material, the food made for auxiliary material with prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials;
Fill a prescription by following raw materials according and consumption thereof: the extract of medicine-food two-purpose: Cordyceps sinensis (aweto mycelium) 7g, stem of noble dendrobium 7g, lucidum spore powder (broken wall) 7g, motherwort 7g, fruit of glossy privet 7g, Radix Astragali 7g, radix bupleuri 7g, bighead atractylodes rhizome 6g, Radix Angelicae Sinensis 6g, root of herbaceous peony 6g, root bark of tree peony 6g, rattletop 6g, tarragon 6g, safflower 6g, dried rhizome of rehmannia 6g, Ligusticum wallichii 6g, radix paeoniae rubrathe 5g, myrrh 5g, seed of Chinese dodder 5g, carbonized hair 5g, oldenlandia diffusa 5g, edible tulip 5g, red sage root 5g, golden cypress 4g, radix scrophulariae 4g, selfheal 4g, Cordyceps militaris 4g, donkey-hide gelatin 4g, Poria cocos 4g, root of Dahurain angelica 4g, ginseng 4g, peach kernel 3g, Chinese yam 3g, matrimony vine 3g, coix seed 3g, dandelion 3g, Semen Benincasae 3g, sophora flower 2g, Radix et Rhizoma Gynurae divaricatae 2g, peppermint 2g, Radix Glycyrrhizae 2g, mountain Cape jasmine 2g, oyster 2g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,
First will to be motherwort during making, the fruit of glossy privet, the Radix Astragali, radix bupleuri, the bighead atractylodes rhizome, Radix Angelicae Sinensis, the root of herbaceous peony, the root bark of tree peony, rattletop, tarragon, safflower, the dried rhizome of rehmannia, Ligusticum wallichii, the radix paeoniae rubrathe, myrrh, the seed of Chinese dodder, carbonized hair, oldenlandia diffusa, edible tulip, the red sage root, golden cypress, radix scrophulariae, selfheal, donkey-hide gelatin, the root of Dahurain angelica, ginseng, matrimony vine, dandelion, Semen Benincasae, sophora flower, Radix et Rhizoma Gynurae divaricatae, peppermint, Radix Glycyrrhizae, mountain Cape jasmine, oyster, the membrane of a chicken's gizzard, Chinese yam, Gorgon fruit soak after add cycloheptaamylose, with prehydrolysis SBE technology extract after, spray-dried and preparation flour, then add biological enzymolysis extract small peptide, prebiotics, amino acid, Cordyceps sinensis (aweto mycelium), the stem of noble dendrobium, lucidum spore powder (broken wall), Cordyceps militaris, carbohydrate, multivitamin and mineral matter, and add Poria cocos, peach kernel, coix seed, carry out pasteurization after donkey-hide gelatin is pulverized and mixed together 1 hour, then add the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus also mixes the solid beverage making powdery, granule, and be distributed into 10g/ bag, after dissolving with about 150ml warm water (45 degree), directly drink or take in through nasal feeding, also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require.
Embodiment two
The full nutritional formulas of the above-mentioned cancer of the uterus also comprises following component by weight: the extract of medicine-food two-purpose: Cordyceps militaris 16g, donkey-hide gelatin 16g, Poria cocos 14g, root of Dahurain angelica 14g, ginseng 14g, peach kernel 14g, Chinese yam 12g, matrimony vine 12g, coix seed 12g, dandelion 12g, Semen Benincasae 10g, sophora flower 10g, Radix et Rhizoma Gynurae divaricatae 10g, peppermint 10g, Radix Glycyrrhizae 8g, mountain Cape jasmine 8g, oyster 8g,
Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g.
Embodiment three
The full nutritional formulas of the above-mentioned cancer of the uterus also comprises following component by weight: the extract of medicine-food two-purpose: Cordyceps militaris 16g, donkey-hide gelatin 16g, Poria cocos 14g, root of Dahurain angelica 14g, ginseng 14g, peach kernel 14g, Chinese yam 12g, matrimony vine 12g, coix seed 12g, dandelion 12g, Semen Benincasae 10g, sophora flower 10g, Radix et Rhizoma Gynurae divaricatae 10g, peppermint 10g, Radix Glycyrrhizae 8g, mountain Cape jasmine 8g, oyster 8g,
Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, carbohydrate 150g, prebiotics 100g, several amino acids 100g.
Embodiment four
The full nutritional formulas of the above-mentioned cancer of the uterus also comprises following component by weight: small peptide 350g, carbohydrate 300g, several amino acids 100g, Bifidobacterium 50g, lactobacillus 50g, streptococcus thermophilus 25g, prebiotics 100g, B B-complex and mineral matter 25g; Energy contained by every 100 g should be not less than 295 kJ (70 kcal).
The present invention with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product improve cancer of the uterus patient immunity significantly improves compared with the like product of market.

Claims (10)

1. the full nutritional formulas of the cancer of the uterus, it is characterized in that the constitutive character in conjunction with cancer of the uterus patient, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with the Chinese medical extract elite of more than 4 kinds medicine-food two-purposes, multiple probio, small peptide for primary raw material, the food made for auxiliary material with prebiotics, carbohydrate, amino acid, multivitamin, several mineral materials;
Fill a prescription by following raw materials according and consumption thereof: the extract of medicine-food two-purpose: Cordyceps sinensis (aweto mycelium) 7g, stem of noble dendrobium 7g, lucidum spore powder (broken wall) 7g, motherwort 7g, fruit of glossy privet 7g, Radix Astragali 7g, radix bupleuri 7g, bighead atractylodes rhizome 6g, Radix Angelicae Sinensis 6g, root of herbaceous peony 6g, root bark of tree peony 6g, rattletop 6g, tarragon 6g, safflower 6g, dried rhizome of rehmannia 6g, Ligusticum wallichii 6g, radix paeoniae rubrathe 5g, myrrh 5g, seed of Chinese dodder 5g, carbonized hair 5g, oldenlandia diffusa 5g, edible tulip 5g, red sage root 5g, golden cypress 4g, radix scrophulariae 4g, selfheal 4g, Cordyceps militaris 4g, donkey-hide gelatin 4g, Poria cocos 4g, root of Dahurain angelica 4g, ginseng 4g, peach kernel 3g, Chinese yam 3g, matrimony vine 3g, coix seed 3g, dandelion 3g, Semen Benincasae 3g, sophora flower 2g, Radix et Rhizoma Gynurae divaricatae 2g, peppermint 2g, Radix Glycyrrhizae 2g, mountain Cape jasmine 2g, oyster 2g, Bifidobacterium 100g, lactobacillus 100g, streptococcus thermophilus 50g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,
Its preparation method is first will to be yellow motherwort, the fruit of glossy privet, the Radix Astragali, radix bupleuri, the bighead atractylodes rhizome, Radix Angelicae Sinensis, the root of herbaceous peony, the root bark of tree peony, rattletop, tarragon, safflower, the dried rhizome of rehmannia, Ligusticum wallichii, the radix paeoniae rubrathe, myrrh, the seed of Chinese dodder, carbonized hair, oldenlandia diffusa, edible tulip, the red sage root, golden cypress, radix scrophulariae, selfheal, donkey-hide gelatin, the root of Dahurain angelica, ginseng, matrimony vine, dandelion, Semen Benincasae, sophora flower, Radix et Rhizoma Gynurae divaricatae, peppermint, Radix Glycyrrhizae, mountain Cape jasmine, oyster, the membrane of a chicken's gizzard, Chinese yam, Gorgon fruit soak after add cycloheptaamylose, with prehydrolysis SBE technology extract after, spray-dried and preparation flour, then add biological enzymolysis extract small peptide, prebiotics, amino acid, Cordyceps sinensis (aweto mycelium), the stem of noble dendrobium, lucidum spore powder (broken wall), Cordyceps militaris, carbohydrate, multivitamin and mineral matter, and add Poria cocos, peach kernel, coix seed, carry out pasteurization after donkey-hide gelatin is pulverized and mixed together 1 hour, then add the Bifidobacterium after microencapsulation, lactobacillus, the various batchings that streptococcus thermophilus also adds appropriate carbohydrate mixing again mix the solid beverage making powdery, granule, and be distributed into 10g/ bag, after dissolving with about 150ml warm water (45 degree), directly drink or take in through nasal feeding, also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require.
2. the full nutritional formulas formula of the cancer of the uterus according to claim 1, it is characterized in that described medicine-food two-purpose Chinese herbal medicine extract is: Cordyceps sinensis (aweto mycelium), the stem of noble dendrobium, lucidum spore powder (broken wall), motherwort, the fruit of glossy privet, the Radix Astragali, radix bupleuri, the bighead atractylodes rhizome, Radix Angelicae Sinensis, the root of herbaceous peony, the root bark of tree peony, rattletop, tarragon, safflower, the dried rhizome of rehmannia, Ligusticum wallichii, the radix paeoniae rubrathe, myrrh, the seed of Chinese dodder, carbonized hair, oldenlandia diffusa, edible tulip, the red sage root, golden cypress, radix scrophulariae, selfheal, Cordyceps militaris, donkey-hide gelatin, Poria cocos, the root of Dahurain angelica, ginseng, peach kernel, Chinese yam, matrimony vine, coix seed, dandelion, Semen Benincasae, sophora flower, Radix et Rhizoma Gynurae divaricatae, peppermint, Radix Glycyrrhizae, mountain Cape jasmine, oyster wherein more than 4 kinds or all mix.
3. the full nutritional formulas formula of the cancer of the uterus according to claim 1, is characterised in that and can be prepared into powdery, graininess, capsule shape, tablet shape, beverage based food according to described formula mixing.
4. the full nutritional formulas formula of the cancer of the uterus according to claim 1, also comprises following component by weight: small peptide 350g, carbohydrate 300g, several amino acids 100g, Bifidobacterium 50g, lactobacillus 50g, streptococcus thermophilus 25g, prebiotics 100g, B B-complex and mineral matter 25g.
5. the full nutritional formulas formula of the cancer of the uterus according to claim 1, is characterized in that described prebiotics is. have that very strong field planting effect prebiotics is Chinese yam to external source probio, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, the extract of jerusalem artichoke, stachyose, yeast and common prebiotics wherein several or all mix.
6. require the full nutritional formulas formula of the cancer of the uterus described in 1, it is characterized in that described amino acid is Glu, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix.
7. the full nutritional formulas formula of the cancer of the uterus according to claim 1, is characterized in that described carbohydrate is Arabinose, fructose, galactolipin, lactose, glucose, maltose, water-soluble dietary fiber, starch, glycogen one wherein, several or all mix.
8. the full nutritional formulas formula of the cancer of the uterus according to claim 1, is characterized in that with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology of the industrialization production of formation; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, make product prevent and treat cancer of the uterus effect and significantly improve compared with the like product of market.
9. the full nutritional formulas formula of the cancer of the uterus according to claim 1, is characterized in that described vitamin is vitamin A, vitamin D, vitamin E, vitamin K, vitamin K1, vitamin C, vitamin B1, vitamin B2, vitamin B6, vitamin B12, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin one wherein, several or all mix; Described mineral matter is calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum one wherein, several or all mix.
10. the full nutritional formulas formula of the cancer of the uterus according to claim 1, is characterized in that described small peptide is marine collagen peptide, maize oligopeptide, wheat oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide is wherein a kind of, several or all mix.
CN201410575369.5A 2014-10-25 2014-10-25 Total nutrient formulation food for uterine cancer Pending CN104256629A (en)

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