CN104996989A

CN104996989A - Medical formula food for blood stasis constitutions

Info

Publication number: CN104996989A
Application number: CN201510161141.6A
Authority: CN
Inventors: 陈昕; 秦孝发; 吴�灿; 胡安然; 蔡缨
Original assignee: Jing Shanmei Biotech Inc
Current assignee: Jing Shanmei Biotech Inc
Priority date: 2015-04-08
Filing date: 2015-04-08
Publication date: 2015-10-28

Abstract

The invention belongs to the technical field of medicinal and edible formulas and new resource foods, and particularly provides a medical formula food, a specific medical formula food or a non-specific medical formula food for patients with blood stasis constitutions to eat. According to the requirements of the <General Rules for Formula Foods for Special Medical Purposes>, combining the constitution characteristics of patients with the blood stasis constitutions, and reasonably mixing various 'medicinal and edible' traditional Chinese medicines according to the quintessence theory of traditional Chinese medicine science, the formula food is prepared by mixing essences extracted from various medicinal and edible traditional Chinese medicines by adopting a prehydrolysis SBE technique, various micro-capsulated probiotics, short peptides extracted through biological enzymolysis, prebiotics, amino acid, carbohydrate, grease with a health-care function, various vitamins and mineral substances and other technologies. Not only can the formula food be used as a single nutrient source to meet the nutritional requirements of the patients with the blood stasis constitutions, but also the formula food has the efficacies of promoting blood circulation for removing blood stasis, promoting flow of qi and blood circulation, removing blood stasis for relieving pain, warming yang for promoting blood circulation and enhancing immunity.

Description

Blood stasis constitutional medicine formula food

Technical field

The invention belongs to integration of drinking and medicinal herbs class formula and new resource food technical field, specifically the Traditional Chinese Medicine marrow of " Chinese medicine of integration of drinking and medicinal herbs " is theoretical and " multiple probio " combines, and adds with small peptide, prebiotics, amino acid, carbohydrate, the blood stasis constitutional medicine formula food, specific full nutritional formulas or the non-fully nutritional formulas that have the grease of health care, B B-complex, composite mineral matter to make for auxiliary material.

Background technology

Blood stasis refers to the one card type in Chinese medical discrimination, blood stasis and blood operation are not smooth, there is hemostasis, blood stasis is found in a variety of disease, generally speaking, all blood leaving passages through which vital energy circulates can not dissipate stagnant in certain with the stasis of blood in time, or thrombosis, operation is obstructed, pool within passages through which vital energy circulates or organ in the state of stagnating, all be blood stasis, blood stasis physique refers in body the pathologic basis of undertone or the extravasated blood internal resistance having blood operation not smooth, take extravasated blood as the constitution status of main manifestations feature, syndrome of blood stasis does not move with shouting pain, tenderness, lump, hemorrhage, words onyx is purple dark, uneven pulses etc. are dialectical main points, hemostasis stops amassing, train of thought is obstructed, mechanism of qi blocks, stagnation of QI and blood may bring about pain, therefore sharp ache, as acupuncture is lancinated, position is fixing not to be moved, because pressing makes mechanism of qi more block, the pain increased and tenderness, night, the moon was arrogant, cloudy blood stagnation and pain more, hemostasis cohesion local, and with the passing of time do not fall apart, just become lump, lump is between skin tissue, and look is livid purple look, if lump is abdominal cavity person, can touch hard tangible block, what push away is motionless, the pain of pressing, and is referred to as scar and amasss, hemostasis blocks channels, and QI-blood circulation is obstructed, and gushes network broken and see hemorrhage with hyperamization, because hemostasis stops not removing in aggressiveness, blocking train of thought, or be again hemorrhage reason, therefore its hemorrhage feature out to stop, repeatedly endlessly, blood-stasis internal-depression, QI-blood circulation is smooth, failure of skin and muscle to be nourished, therefore darkish complexion, and pachylosis is as scale and shell, and even lip onyx is purple dark, and the position of hemostasis is different, and clinical manifestation is also different, and such as stasis blocking is subcutaneous, then subcutaneously see ecchymosis, stasis blocking flesh table channels, skin surface occurs thread as thread, stasis blocking liver arteries and veins, be then shown in that belly blue veins exposes, stasis blocking lower limb, be then shown in shank blue veins protuberance, bend, even curl agglomerating, blood-stasis internal-depression, the not life of new blood, women is as seen through closing, tongue is purple dark, and thready and hesitant pulse is common the resembling of hemostasis, the reason that blood stasis physique is formed: 1, Familial Occurrence, 2, the obstruction of the circulation of vital energy causes blood stasis, 3, the deficiency of vital energy causes blood stasis, and 4, the deficiency of yang is cold and cool causes blood stasis, 5, the cloudy liquid of the deficiency of Yin, damp and hot → thermal burn, water is few, and blood is thick causes blood stasis, 6, and phlegm is wet causes blood stasis " integration of drinking and medicinal herbs " to be to one of contribution of mankind's most worthy among Chinese original medical science, the traditional Chinese medical science is always emphasized " medication not as dietotherapy ", dietotherapy become modern pursue recover one's original simplicity, the optimal selection of health diet, allow people dispel slight illness in the process enjoying cuisines, avoid and have an injection, take medicine, even pain of surgery,

For food of special nutrients, there are corresponding regulation and Application and Development in the developed country such as the U.S., European Union; And the full nutritional formulas of wholefood clear stipulaties: 2.1.1 in China GB29922-2013 " special medicine purposes formula food general rule " national food safety standard: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need; 2.1.2 specific full nutritional formulas: can be used as the special medicine purposes formula food that single source of nutrition meets target group's nutritional need under specified disease or medical condition;

Deficiency of blood physique person mostly also is the patient of stomach Flora Disturbance, and traditional Chinese medical science traditional medicine is thought: " spleen (i.e. digestive system) is the foundation of acquired constitution ", and stomach health is healthy basis, and 99% of human nutrition needs by intestinal absorption, and intestinal bowel disease is also the source of ten thousand diseases; But along with the age is larger, in enteron aisle, profitable strain (probio) ratio reduces gradually; As Bifidobacterium accounts for 98% infant period, be down to 10% to during the middle age, within 65 years old, only account for 5% later; People is older, and probio is fewer, and function of intestinal canal also declines thereupon gradually, more and more studies display, normal flora human consumption, immunity and disease-resistant etc. in have many irreplaceable effects; The change of gut flora composition and the generation of various diseases, particularly intestines problem develop closely related, and find from existing clinical research: probio can play regulating intestinal canal flora, controls intestinal inflammatory effect, is that one intervenes control method safely and effectively;

Though direct probiotic oral has certain effect, but due to probio cannot field planting in enteron aisle, and stop, occupy-place is little, easily run off, withdraw rear harmful bacteria and easily recur, associated patient needs long-term taking, and treatment cycle is long, often uses afterwards that recurrence rate is very high, for shortening the treatment cycle of associated patient, recurrence rate after minimizing drug withdrawal, this team is by the key technology research to probio field planting mechanism in enteron aisle over nearly 3 year, make great efforts " Chinese medicine of the integration of drinking and medicinal herbs " compound seeking to improve probio field planting in enteron aisle, consider several key elements of probio field planting in enteron aisle: the existence of prebiotics can play field planting effect, the reduction of intestinal pH environment and the enteron aisle adhesive capacity etc. of raising probiotic cell, based on above-mentioned key element, suitable food materials screen from tens of kinds " Chinese medicines of integration of drinking and medicinal herbs " in this seminar, Late Cambrian interpolation Chinese yam, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, the extract of the traditional Chinese medicine ingredients of the integration of drinking and medicinal herbs such as Gorgon fruit and jerusalem artichoke and stachyose, yeast, after Glu etc., very strong field planting effect is had to external source probio, prescription for probio in enteral microecological formulation is selected to provide experimental basis,

Favourable is in the market primary raw material in order to eat source property small peptide, add the mushroom of medicine-food two-purpose, dried orange peel, matrimony vine, Chinese yam, Poria cocos, the extract of sealwort etc., B B-complex and mineral matter composition compound prescription, utilize the product that probio is primary raw material in addition, but also do not find the constitutive character in conjunction with blood stasis physique person, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility is with the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, amino acid, there is the grease of health care, multivitamin, several mineral materials is the medical science formula food that auxiliary material is made, specific full nutritional formulas or similar products.

goal of the invention

The object of the invention is on the theoretical treatment method of succession traditional Chinese medical science marrow, the initiative extract by the probio of the immunity of multiple raising blood stasis physique person and " Chinese medicine of integration of drinking and medicinal herbs " compound combines, add with small peptide, amino acid, carbohydrate, there is the grease of health care, multivitamin, several mineral materials is auxiliary material, the blood stasis physique person institute essential nutrients of hypoimmunity can not only be supplemented, improve body nutrition condition, can also and utilize function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function, probio can play regulating intestinal canal flora, toxic and side effect is little, safe and effective, and the medical science formula food that the acceptable applicable blood stasis physique person of people eats, specific full nutritional formulas or non-fully nutritional formulas.

summary of the invention:

This R&D team is according to the requirement of " special medicine purposes formula food general rule ", the constitutive character of the blood stasis physique person that binding immunoassay power is low, the advanced physiology of comprehensive nowadays American Harvard University, medicine, the achievement in research such as nutrition and clinical practice, according to " the middle residence that disappears benefit ", marrow theory (the liver of the Traditional Chinese Medicine of " equilibrium is taken good care of ", spleen, kidney three is dirty with being adjusted to main principle), adopt a kind of, the Chinese medical extract elite of several or whole mixing medicine-food two-purpose and new resource food, multiple probio, small peptide is primary raw material, with prebiotics, carbohydrate, there is the grease of health care, amino acid, multivitamin and mineral matter auxiliary material, not only can be used as the nutritional need that single source of nutrition meets blood stasis physique person, promoting blood circulation and removing blood stasis in addition, the promoting flow of qi and blood circulation, stasis-dispelling and pain-killing, Wen Yang invigorates blood circulation and the medical science formula food of effect of develop immunitypty, specific full nutritional formulas or non-fully nutritional formulas (compound prescription be combined into),

1, the main component of the present invention's formula is:

Chinese medical extract is dirty with being adjusted to main principle from the liver,spleen,kidney three theory of traditional Chinese medical science according to the constitutive character of blood stasis physique, utilizes the function factor in medicine-food two-purpose Chinese herbal medicine to regulate body function to build up resistance, and chooses following several large class medicine and carry out compatibility; Wherein: Radix Angelicae Sinensis taste is sweet, pungent, warm, enriches blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation; The fleece-flower root is bitter sweet puckery, tepor, nourishing the blood and yin; Relax bowel; Preventing malaria; Dispel the wind; Removing toxic substances, radix bupleuri nature and flavor are bitter, are slightly cold, return liver, gallbladder channel, and in having and inducing sweat, soothing the liver, rise effect of sun, the bighead atractylodes rhizome has strengthening the spleen and replenishing qi, eliminating dampness Li Shui, hidroschesis, antiabortive effect, and motherwort taste is arduous, cool, and invigorate blood circulation, silt of dispelling, menstruation regulating, disappear water, red sage root nature and flavor hardship, is slightly cold; The thoughts of returning home, Liver Channel, have stasis-dispelling and pain-killing, activating blood to promote menstruation, the effect of the relieving restlessness that clears away heart-fire, and the pungent and sweet temperature of safflower is bitter, and activating blood to promote menstruation, goes stasis of blood pain relieving, and Radix et Rhizoma Gynurae divaricatae taste is pungent, light; Property is put down, hypoglycemic, clearing heat and cooling blood; Promoting blood circulation and stopping pain; Hemostasis, mulberries nourishing yin and supplementing blood, promote the production of body fluid moisturize, ease constipation toxin expelling, Colla Corii Asini nourishing blood enriching yin, moisturizes, hemostasis, effect that peach kernel has promoting blood circulation, relaxes bowel;

Medicinal and edible Chinese medicine extract of the present invention refers to Radix Angelicae Sinensis, the fleece-flower root, radix bupleuri, the bighead atractylodes rhizome, motherwort, the red sage root, safflower, dendrobium candidum, Cordyceps sinensis (aweto mycelium), lucidum spore powder (broken wall), Radix et Rhizoma Gynurae divaricatae, mulberries, hawthorn, lotus leaf, sea-buckthorn, mountain Cape jasmine, rose, the root of kudzu vine, peach blossom, line leaf broom top, ampelopsis grossdentata leaf, Euglena, combined spicebush leaf, Tea Flower, haematococcus pluvialis, Camellia nitidissima, leaf of Moringa, Noni fruit, eucommia Bark male flower, phoenix peony, Guangdong Cordyceps militaris, Cordyceps sinensis (aweto mycelium), Cordyceps militaris, lucidum spore powder (broken wall), donkey-hide gelatin, peach kernel, chlorella pyrenoidosa, Saussurea involucrata culture, currant lobate layer bacterium fermentation mycelium, ground dragon protein, first milk basic protein one wherein, several or whole, biological enzymolysis or prehydrolysis SBE is adopted to extract and microencapsulation, mixture after spray-dried and cryodesiccated extract,

2, multiple probio: make probio major part can arrive enteron aisle by the strong acid environment of stomach, to promote the propagation of probio, regulate microecological balance in intestines, promote the absorption to trace element, strengthen taste motor function, accelerate the absorption of drug effect, improve the micropopulation of mucous membrane surface or the balance of enzyme, or stimulate body specificity or nonspecific immunity mechanism, improve body colonization resistance or immunity; Xing etc., with Bifidobacterium and Bacillus acidi lactici pretreatment law during ischemia/reperfusion rat, obviously can reduce the level of intestinal endotoxemia and the generation of preventing liver injury; Selective enteron aisle decontamination dye is also the important measures of adjustment intestinal microecology, has research application enteron aisle not absorb rifamycin antibiotic former times bright (rifaximin), by urease-producing in suppression enteron aisle and the growth of producing ammonium bacteria, builds up resistance;

Multiple probio of the present invention all adopts the probio after microencapsulation, and the probio described in it is: Bifidobacterium, lactobacillus, streptococcus thermophilus, Pediococcus acidilactici are wherein a kind of, several or all mix;

Bifidobacterium above a refers to: bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum, animal bifidobacteria (bifidobacterium lactis);

Lactobacillus above b refers to: lactobacillus acidophilus, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii subspecies, lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, Lactobacillus plantarum, lactobacillus paraceasi, Yue Shi lactobacillus, lactobacillus paraceasi, Lactobacillus crispatus, lactobacillus delbruockii subspecies bulgaricus, lactobacillus reuteri;

3, small peptide: be oligopeptide, refer to the small molecule protein utilizing bio-enzyme engineering technology separation and Extraction from animal or vegetable protein, its mean molecule quantity is at below 1000Dalton, soluble in water, to acid, thermally-stabilised, can not need directly to absorb through digestion, bioavailability is high, absorbing and utilizing the amino acid and complete protein that are better than dissociating, can be applicable in Protein intake food, especially for the crowd that abilities of digestive and absorption is low, small peptide is splendid nitrogenous source, except trophic function, small peptide also has a series of physiological active functions: the digestion and absorption function improving small intestine, strengthen immunity of organisms, anti-oxidant, auxiliary adjustment blood sugar, auxiliary adjustment of blood fat, aided blood pressure-lowering, radioresistance, promote mineral absorption, strengthen the action effect of function factor in medicine-food two-purpose Chinese herbal medicine,

Small peptide of the present invention refers to that maize oligopeptide, wheat oligopeptide, marine collagen peptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide are wherein a kind of, several or all mix;

4, prebiotics: with short probio intestinal colonisation, enteron aisle convergence, reduce intestinal pH environment, also do not utilized by most enteron aisle spoilage organisms, but beneficial bacteria in human body can be promoted---the growth and breeding of lactobacillus, Bifidobacterium, thus spoilage organisms can be suppressed to grow, contribute to improving and maintaining enteron aisle normal function; Long-term edible can to delay senility, defaecation, raising immunity, the absorptivity that alleviates burden of liver, improve nutrient, particularly can improve the absorption of body to metal ions such as calcium, iron, zinc; Optionally promote outside the growth and breeding of beneficial bacterium (bifid, lactic acid), also can metabolism be acid product as organic acids such as lactic acid, knot intestinal pH is reduced, suppresses the growth of intestinal harmful bacillus; Water-Electrolyte in small intestine is made to be trapped in enteric cavity, produce and highly ooze effect, enterocinesia is stimulated to cause laxative, thus promote the discharge of intestinal endotoxin and other toxicants, lactulose also can directly endotoxin in deactivation enteron aisle, reduce gut pH, extensively model is applied to the treatment of enhancing blood stasis physique resistance;

Prebiotics of the present invention is 2 classes

A. have very strong field planting effect prebiotics to external source probio: Chinese yam, Poria cocos, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, jerusalem artichoke extract;

B. common prebiotics: oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide, cotton seed compound sugar, trehalose, stachyose, yeast;

Prebiotics of the present invention is: the extract of Chinese yam, Poria cocos, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, jerusalem artichoke, cotton seed compound sugar, trehalose, stachyose, yeast, oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix;

5. carbohydrate: carbohydrate is by carbon, hydrogen and oxygen three kinds of element compositions, it is for human body provides nutrient the most cheap in three of heat energy kinds of main nutrients, when taking in sufficient, energy can be provided in time by rapid oxidation in vivo, the protein of preciousness is avoided to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the glycolipid of nerve fiber and the important composition composition of DNA (DNA) conveyed hereditary information, and the glycogen contained in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin that some poisonous chemical substance and various pathogenic microorganisms produce,

Carbohydrate of the present invention refers to Arabinose, fructose, swan-mussel polysaccharide, resistant dextrin, chitosan oligosaccharide, yeast beta-dextran, galactolipin, lactose, glucose, maltose, water-soluble dietary fiber, starch, glycogen one wherein, several or all mix;

6. there is the grease of health care to refer to there is health-care effect to the person, and finished product energy can be increased, make the energy contained by every 100 g of finished product of the present invention should be not less than 295 kJ (70 kcal); As the street cleaner that fish oil is human vas, can also prevention of arterial sclerosis, apoplexy and heart disease.Fish oil is the diseases such as hypertension, coronary heart disease, headstroke, diabetes, rheumatic arthritis, cancer; Linseed oil has fat-reducing, reduces cholesterol, improves the effects such as renal function; Peony seed oil has reducing blood lipid and hypotensive, strengthens autoimmunity, prevention diabetes, effect of anti-curing cancers; Samara oil prevents and treats hypertension, high fat of blood, effect of the illnesss such as vascular sclerosis;

Of the present invention have the grease of health care to refer to linseed oil, peony seed oil, samara oil, silybum marianum seed oil, phytosterin ester, imperial rice bran oil, tea seed oil, fish oil, fish oil extract, arachidonic acid oil, SPE, DHA algal oil, krill oil, Suaeda salsa seed oil, U.S. rattan fruit oil, rhus glabra oil, medium chain triglyceride, oxhide gelatin, smooth bark Lai wood fruit oil, amygdalus pedunculata pall oil, middle LCFA edible oil, acer truncatum seed oil, Epigallo-catechin gallate (EGCG), triglyceride oil, lutein ester one wherein, several or all mix,

7, amino acid: be divided into essential amino acid and nonessential amino acid, is the base unit forming protein, gives protein specific molecular morphosis, make it have biochemical activity; Absorb appropriate methionine and contribute to the metabolism of various sulfur-containing compound in human body and the methyl contained by it methylates to Toxic or medicine and plays the effect of removing toxic substances; Leucine can repair muscle, controls blood sugar, and provides energy to bodily tissue, essential amino acid phenylalanine can suppress cancer growth, can reduce again the toxic and side effect of medicine, and lysine can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development; Arginine contributes to changing the ammonia in blood into urea and excreting out; For hyperammonemia, hepatic dysfunction etc. are all powerful; Histidine reduces gastric acidity, relaxes the pain of gastrointestinal procedures, alleviates gestational period vomiting and scorching hot sense, suppresses nervous by vegetative nerve and alimentary canal that is that cause festers, to anaphylactia, as also powerful in asthma etc.; Tryptophan can prevent pellagra, depression, improving water flood and adjustment mood;

Amino acid of the present invention refers to Glu, GABA, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix;

8, vitamin and mineral matter: vitamin and mineral matter are the nutrients of needed by human, the nutrient of the vitamin added in the present invention to be vitamin and mineral matter be needed by human;

The vitamin added in the present invention is vitamin A, vitamin D, vitamin E, vitamin K, vitamin K1, vitamin C, vitamin B1, vitamin B2, vitamin B6, vitamin B12, Cobastab e, Cobastab u, nicotinic acid, folic acid, pantothenic acid, choline, biotin one wherein, several or all mix;

The mineral matter added in the present invention is calcium, phosphorus, potassium, sodium, magnesium, chlorine, iron, zinc, selenium, copper, manganese, iodine, fluorine, chromium, molybdenum one wherein, several or all mix, and mineral matter of the present invention is added to the organic or inorganic compound of this mineral matter;

In the present invention, the addition of vitamin and minerals performs with reference to " special medicine purposes formula food general rule ", now for 1000g finished product, addition is vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,

The present invention with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product strengthen blood stasis physique resistance significantly improves compared with the like product of market;

9. adopt above-mentioned integrated innovation technique various batching to be mixed solid beverage, the granule of making powdery, and be distributed into 10g/ bag, after dissolving with about 150ml warm water (45 degree), directly drink or take in through nasal feeding; Also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require;

The characteristic of this full nutritional formulas of filling a prescription and the following aspects is mainly manifested in the effect of body:

1. the present invention is the requirement according to " special medicine purposes formula food general rule ", in conjunction with the constitutive character of blood stasis physique person, the achievement in research developments such as the advanced physiology of comprehensive nowadays American Harvard University, medicine, nutrition and clinical practice, vary with each individual, gold compatibility;

2. the present invention is according to the marrow theory (liver,spleen,kidney three is dirty with being adjusted to main principle) of the Traditional Chinese Medicine of " the middle residence that disappears is mended ", " equilibrium is taken good care of ", the Chinese medical extract elite of multiple medicine-food two-purpose, multiple probio, small peptide is adopted to be primary raw material, with prebiotics, carbohydrate, amino acid, the grease having health care, multivitamin and mineral matter for auxiliary material, the organic assembling of various batching, various function is merged, and by the synergy between active ingredient, humidification effect;

3. have effective absorbency, utilize formula of the present invention, various component adopts the food of suitable ratio collocation preparation, in isotonic state after a certain amount of water-soluble solution, small intestine can be arrived quickly through stomach, absorb fast, completely, blood stasis physique person desired nutritional can be supplemented rapidly;

4. in the present invention's formula, adopt the extract of various medicine-food two-purpose Chinese herbal medicine, containing several functions active component, not only increase the concentration of function factor, reduce the absorption of various impurity, contribute to alleviating liver kidney burden, have and strengthen the effect of resistance of human body, promoting blood circulation and removing blood stasis, the promoting flow of qi and blood circulation in addition, stasis-dispelling and pain-killing, Wen Yang invigorate blood circulation and effect of develop immunitypty, 5. probio contained in the present invention's formula, multiple probio can safeguard enteron aisle normal bacteria colony balance, suppress the growth of pathogen, prevent gastrointestinal disorders etc., synthetic vitamin in enteron aisle, amino acid and raising body are to the absorption of calcium ion, strengthen human immunologic function, prevent antibiotic side effect, improve host to the tolerance of radioactive ray, lactobacillus significantly increases intestinal mucosal immune globulin A (SIgA) content, to body intestinal mucosa local immunity, there is regulating action, regulate stomach, intestines Tiny ecosystem, calcium can be improved, phosphorus, the utilization rate of iron, promote the absorption of iron and vitamin D, produce vitamin K and Cobastab, the absorption of cholesterol can also be reduced,

6. formula food of the present invention with the food source property bioactive short peptide in multiple source for nitrogenous source, because small peptide does not need digestion and Absorbable rod, more be conducive to the utilization of body, effectively can improve blood stasis physique person negative nitrogen balance, and food source property small peptide can improve the 26S Proteasome Structure and Function of intestinal epithelial cell, improves the absorbability of intestinal mucosa;

7. this prescription have employed this team by the achievement to probio key technology research of field planting mechanism in enteron aisle over nearly 3 year, improve " Chinese medicine of integration of drinking and medicinal herbs " compound of probio field planting in enteron aisle, the existence combining prebiotics can play the key elements such as field planting effect, the reduction of intestinal pH environment and the enteron aisle adhesive capacity of raising probiotic cell, and therefore the composition of this food formula greatly strengthen the field planting effect to external source probio;

8. prebiotics contained in the present invention's formula, by promoting the growth and breeding of probio in intestines, suppress the growth of spoilage organisms, form one protective barrier at intestinal mucosal surface simultaneously, the damage of enteron aisle spoilage organisms to intestinal mucosa can be resisted, reduce the absorption of intestinal toxic material, intestines peristalsis can also be promoted, accelerate the discharge of residuals in intestines, constipation can be prevented, and by promoting that the growth and breeding of beneficial bacteria of intestinal tract also can strengthen immunity of organisms, the bioactivators such as small peptide, carbohydrate and active polysaccharide have synergy;

9, in the present invention's formula, contained carbohydrate is for human body provides three of heat energy kinds of main nutrients, energy can be provided in time by rapid oxidation in vivo, the protein of preciousness is avoided to be used to provide energy, carbohydrate is also the glycoprotein of cell membrane, the glycolipid of nerve fiber and the important composition composition of DNA (DNA) conveyed hereditary information, and the glycogen contained in carbohydrate, when it lays in abundance in liver, liver cell has stronger detoxification ability to the toxin that some poisonous chemical substance and various pathogenic microorganisms produce,

10, in the present invention's formula, the contained grease of health care that has not only has health-care effect to the person, and provide the energy needed for normal life for human body, make the energy contained by the every 100g of finished product of the present invention should be not less than 295 kJ (70 kcal);

11, contained in the present invention's formula amino acid, it is the base unit forming protein, give protein specific molecular morphosis, make it have biochemical activity, contribute to the metabolism of various sulfur-containing compound in human body and the methyl contained by it methylates to Toxic or medicine and plays the effect of removing toxic substances, muscle can be repaired, control blood sugar, and provide energy to bodily tissue, also can improve absorption and the utilization of food protein, reach balanced nutritious, enhancing development;

12, formula food of the present invention is containing multivitamin and mineral matter, can supplement rapidly the micronutrient needed for blood stasis physique, small peptide by with the chelating of calcium, iron, zinc etc. after, further increase the absorptivity of mineral matter element;

13, not fatty and cholesterol in the present invention's formula, while supplementary protein, micronutrient, can not increase the absorption of fat, cholesterol, avoid the adverse effect of the high protein diet such as meat, egg.

Detailed description of the invention

Below by following case study on implementation, the invention will be further described, and it will contribute to understanding the present invention;

Case study on implementation one

Realizing the object of the invention blood stasis constitutional medicine formula food is constitutive character in conjunction with blood stasis physique person, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with a kind of, several or whole medicinal and edible Chinese medicine extract essences and new resource food, multiple probio, small peptide for primary raw material, with prebiotics, carbohydrate, amino acid, the medical science formula food that has the grease multivitamin of health care, several mineral materials to make for auxiliary material;

Fill a prescription by following raw materials according and consumption thereof: the extract of medicine-food two-purpose and new resource food: Radix Angelicae Sinensis 12g, fleece-flower root 12g, radix bupleuri 11g, bighead atractylodes rhizome 11g, motherwort 10g, red sage root 10g, safflower 9g, dendrobium candidum 9g, Cordyceps sinensis (aweto mycelium) 8g, lucidum spore powder (broken wall) 8g, Cordyceps militaris 7g, Radix et Rhizoma Gynurae divaricatae 7g, mulberries 7g, donkey-hide gelatin 7g, peach kernel 6g, hawthorn 6g, lotus leaf 6g, sea-buckthorn 6g, mountain Cape jasmine 6g, rose 6g, root of kudzu vine 5g, peach blossom 5g, line leaf broom top 5g, ampelopsis grossdentata leaf 5g, Euglena 4g, combined spicebush leaf 4g, Tea Flower 4g, haematococcus pluvialis 4g, Camellia nitidissima 3g, leaf of Moringa 3g, Noni fruit 3g, eucommia Bark male flower 2g, phoenix peony 2g, the sub-1g of Guangdong Cordyceps militaris, chlorella pyrenoidosa 7g, Saussurea involucrata culture 5g, currant lobate layer bacterium fermentation mycelium 2g, ground dragon protein 2g, first milk basic protein 1g, multiple probio 300g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, there is the grease 100g of health care, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,

First will to be Radix Angelicae Sinensis during making, the fleece-flower root, radix bupleuri, the bighead atractylodes rhizome, motherwort, the red sage root, safflower, dendrobium candidum, Cordyceps sinensis (aweto mycelium), lucidum spore powder (broken wall), Radix et Rhizoma Gynurae divaricatae, mulberries, hawthorn, lotus leaf, sea-buckthorn, mountain Cape jasmine, rose, the root of kudzu vine, peach blossom, line leaf broom top, ampelopsis grossdentata leaf, Euglena, combined spicebush leaf, Tea Flower, haematococcus pluvialis, Camellia nitidissima, leaf of Moringa, Noni fruit, eucommia Bark male flower, phoenix peony soak after add cycloheptaamylose, with prehydrolysis SBE technology extract after, spray-dried and preparation flour, then add biological enzymolysis extract Cordyceps sinensis (aweto mycelium), Guangdong Cordyceps militaris, Cordyceps militaris, lucidum spore powder (broken wall), donkey-hide gelatin, peach kernel, chlorella pyrenoidosa, Saussurea involucrata culture, currant lobate layer bacterium fermentation mycelium, ground dragon protein, first milk basic protein, small peptide, prebiotics, amino acid, carbohydrate, there is the grease of health care, carry out pasteurization after multivitamin and mineral matter are pulverized and mixed together 1 hour, then add the Bifidobacterium after microencapsulation, lactobacillus, streptococcus thermophilus also mixes the solid beverage making powdery, granule, and be distributed into 10g/ bag, after dissolving with about 150ml warm water (45 degree), directly drink or take in through nasal feeding, also can add appropriate attached material make capsule, tablet or add sweetener and black sesame powder make biscuit etc. fast, instant food is convenient to go out to carry edible, if make beverage, save spray-dried, add auxiliary material etc. less, be distributed into 10-65ml/ bottle, early, middle and late 0.5 hour after meal of every day is drink 1 bottle respectively, and all operations all carries out meeting in the clean dried environment that " special medicine purposes formula food Good Manufacture Practice " require,

Manufacture craft of the present invention with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology that the industrialization of formation is produced; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product prevent and treat blood stasis physique significantly improves compared with the like product of market.

Case study on implementation two

Above-mentioned blood stasis constitutional medicine formula food also comprises following component by weight, the extract of medicine-food two-purpose: Cordyceps militaris 7g, Radix et Rhizoma Gynurae divaricatae 7g, mulberries 7g, donkey-hide gelatin 7g, peach kernel 6g, hawthorn 6g, lotus leaf 6g, sea-buckthorn 6g, mountain Cape jasmine 6g, rose 6g, root of kudzu vine 5g, peach blossom 5g, line leaf broom top 5g, ampelopsis grossdentata leaf 5g, Euglena 4g, combined spicebush leaf 4g, Tea Flower 4g, haematococcus pluvialis 4g, Camellia nitidissima 3g, leaf of Moringa 3g, Noni fruit 3g, eucommia Bark male flower 2g, phoenix peony 2g, the sub-1g of Guangdong Cordyceps militaris, chlorella pyrenoidosa 7g, Saussurea involucrata culture 5g, currant lobate layer bacterium fermentation mycelium 2g, ground dragon protein 2g, first milk basic protein 1g, prebiotics 350g, probio 300g, small peptide 150g, several amino acids 100g, carbohydrate 100g, there is the grease 100g of health care, water-soluble dietary fiber 50g, vitamin and mineral matter 25g.

Case study on implementation three

Above-mentioned blood stasis constitutional medicine formula food also comprises following component by weight: the Chinese medical extract elite of several medicine-food two-purpose and new resource food 400g, prebiotics 350g, small peptide 350g, carbohydrate 300g, the grease 300g, the several amino acids 100g that have health care, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).

Case study on implementation four

The certain medical formula food of above-mentioned blood stasis physique also comprises following component by weight: prebiotics 700g, small peptide 500g, carbohydrate 300g, multiple probio 300g, several amino acids 100g, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).

Case study on implementation five

Above-mentioned blood stasis constitutional medicine formula food also comprises following component by weight: prebiotics 500g, small peptide 350g, carbohydrate 300g, multiple probio 250g, several amino acids 100g, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).

Case study on implementation six

Above-mentioned blood stasis constitutional medicine formula food also comprises following component by weight: small peptide 350g, prebiotics 350g, carbohydrate 300g, the grease 300g, the several amino acids 100g that have health care, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295kJ (70kcal).

Claims

1. blood stasis constitutional medicine formula food, it is characterized in that the constitutive character in conjunction with blood stasis physique patient, marrow according to Traditional Chinese Medicine is theoretical, vary with each individual, gold compatibility with a kind of, several or whole medicinal and edible Chinese medicine extract essences and new resource food, multiple probio, small peptide for primary raw material, with prebiotics, carbohydrate, amino acid, the medical science formula food that has the grease of health care, multivitamin, several mineral materials to make for auxiliary material;

Fill a prescription by following raw materials according and consumption thereof, the extract of medicine-food two-purpose and new resource food: Radix Angelicae Sinensis 12g, fleece-flower root 12g, radix bupleuri 11g, bighead atractylodes rhizome 11g, motherwort 10g, red sage root 10g, safflower 9g, dendrobium candidum 9g, Cordyceps sinensis (aweto mycelium) 8g, lucidum spore powder (broken wall) 8g, Cordyceps militaris 7g, Radix et Rhizoma Gynurae divaricatae 7g, mulberries 7g, donkey-hide gelatin 7g, peach kernel 6g, hawthorn 6g, lotus leaf 6g, sea-buckthorn 6g, mountain Cape jasmine 6g, rose 6g, root of kudzu vine 5g, peach blossom 5g, line leaf broom top 5g, ampelopsis grossdentata leaf 5g, Euglena 4g, combined spicebush leaf 4g, Tea Flower 4g, haematococcus pluvialis 4g, Camellia nitidissima 3g, leaf of Moringa 3g, Noni fruit 3g, eucommia Bark male flower 2g, phoenix peony 2g, the sub-1g of Guangdong Cordyceps militaris, chlorella pyrenoidosa 7g, Saussurea involucrata culture 5g, currant lobate layer bacterium fermentation mycelium 2g, ground dragon protein 2g, first milk basic protein 1g, multiple probio 300g, small peptide 200g, prebiotics 100g, several amino acids 100g, carbohydrate 100g, there is the grease 100g of health care, vitamin A 0.01g, vitamin D 0.000015g, vitamin E 0.12g, vitamin K 0.0075g, vitamin K1 0.00001g, vitamin C 10.625g, vitaminB10 .016g, vitamin B2 0.016g, vitamin B6 0.015g, Cobastab 0.0023g, Cobastab e, Cobastab u, nicotinic acid 0.2g, folic acid 0.003g, pantothenic acid 0.051g, choline 2.5g, biotin 0.000057g, calcium 6.2g, phosphorus 4.5g, potassium 10g, sodium 16.17g, magnesium 1.7g, chlorine, iron 0.15g, zinc 6.2g, selenium 0.00012g, copper 0.007g, manganese 0.018g, iodine 0.00001g, fluorine 0.00001g, chromium 0.00001g, molybdenum 0.00001g,

Manufacture craft of the present invention is characterized in that with microcapsules, biological enzymolysis, prehydrolysis SBE, spraying dry and freeze drying integrated innovation, the key technology of the industrialization production of formation; Microencapsulation resist technology, to efficiently solve in oral process high temperature and strong acid gastric juice to the deactivation of probio; Adopt three layers of buried microcapsules technology of protein, Chinese medical extract again with extract also microencapsulation process through biological enzymolysis or prehydrolysis SBE technology after mixes, to solve the coexistence problems of " multiple probio " and " Chinese medicine of integration of drinking and medicinal herbs " component, there is certain high temperature resistance and strong acid characteristic, be conducive to probio and stop field planting by oral arrival in enteron aisle by gastric juice smoothly, the effect making product prevent and treat blood stasis physique significantly improves compared with the like product of market.

2. blood stasis constitutional medicine formula food according to claim 1, it is characterized in that described medicine-food two-purpose Chinese herbal medicine extract and new resource food are: Radix Angelicae Sinensis, the fleece-flower root, radix bupleuri, the bighead atractylodes rhizome, motherwort, the red sage root, safflower, dendrobium candidum, Cordyceps sinensis (aweto mycelium), lucidum spore powder (broken wall), Radix et Rhizoma Gynurae divaricatae, mulberries, hawthorn, lotus leaf, sea-buckthorn, mountain Cape jasmine, rose, the root of kudzu vine, peach blossom, line leaf broom top, ampelopsis grossdentata leaf, Euglena, combined spicebush leaf, Tea Flower, haematococcus pluvialis, Camellia nitidissima, leaf of Moringa, Noni fruit, eucommia Bark male flower, phoenix peony, Guangdong Cordyceps militaris, Cordyceps sinensis (aweto mycelium), Cordyceps militaris, lucidum spore powder (broken wall), donkey-hide gelatin, peach kernel, chlorella pyrenoidosa, Saussurea involucrata culture, currant lobate layer bacterium fermentation mycelium, ground dragon protein, first milk basic protein one wherein, several or all mix.

3. blood stasis constitutional medicine formula food according to claim 1, is characterised in that and can be prepared into powdery, graininess, capsule shape, tablet shape, beverage based food according to described formula mixing.

4. blood stasis constitutional medicine formula food according to claim 1, also comprises following component by weight: the Chinese medical extract elite of several medicine-food two-purpose and new resource food 400g, prebiotics 350g, small peptide 350g, carbohydrate 300g, the grease 300g, the several amino acids 100g that have health care, B B-complex and mineral matter 25g; Energy contained by every 100g should be not less than 295 kJ (70 kcal).

5. blood stasis constitutional medicine formula food according to claim 1, is characterized in that described probio is: Bifidobacterium, lactobacillus, streptococcus thermophilus, Pediococcus acidilactici, wherein a kind of, several or all mix;

Bifidobacterium above refers to: bifidobacterium adolescentis, bifidobacterium lactis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium infantis, bifidobacterium longum, animal bifidobacteria (bifidobacterium lactis);

Lactobacillus above refers to: lactobacillus acidophilus, Lactobacillus casei, lactobacillus bulgaricus, Lactobacillus delbrueckii, newborn subspecies lactobacillus gasseri, lactobacillus fermenti, Lactobacillus helveticus, Lactobacillus salivarius, Lactobacillus rhamnosus, lactobacillus reuteri, Lactobacillus plantarum, lactobacillus paraceasi, Yue Shi lactobacillus, lactobacillus paraceasi, Lactobacillus crispatus, lactobacillus delbruockii subspecies bulgaricus, lactobacillus reuteri.

6. blood stasis constitutional medicine formula food according to claim 1, it is characterized in that described prebiotics is: the extraction mixture of Chinese yam, Poria cocos, heart of a lotus seed benevolence, the membrane of a chicken's gizzard, Gorgon fruit, jerusalem artichoke, cotton seed compound sugar, trehalose, stachyose, yeast, oligoisomaltose, FOS, soyabean oligosaccharides, xylo-oligosaccharide one wherein, several or all mix.

7. blood stasis constitutional medicine formula food according to claim 1, is characterized in that described amino acid is: Glu, GABA, methionine, isoleucine, tyrosine, phenylalanine, lysine, arginine, histidine, tryptophan, citrulling, ornithine, taurine one wherein, several or all mix.

8. the medical science formula food of blood stasis physique according to claim 1, is characterized in that described carbohydrate is that carbohydrate of the present invention refers to Arabinose, fructose, swan-mussel polysaccharide, resistant dextrin, chitosan oligosaccharide, yeast beta-dextran, galactolipin, lactose, glucose, maltose, water-soluble dietary fiber, starch, glycogen one wherein, several or all mix.

9. liver cancer medical science formula food according to claim 1, it is characterized in that the described grease of health care that has is: refer to linseed oil, peony seed oil, samara oil, silybum marianum seed oil, phytosterin ester, imperial rice bran oil, tea seed oil, fish oil, fish oil extract, arachidonic acid oil, SPE, DHA algal oil, krill oil, Suaeda salsa seed oil, U.S. rattan fruit oil, rhus glabra oil, medium chain triglyceride, oxhide gelatin, smooth bark Lai wood fruit oil, amygdalus pedunculata pall oil, middle LCFA edible oil, acer truncatum seed oil, Epigallo-catechin gallate (EGCG), triglyceride oil, lutein ester one wherein, several or all mix.

10. blood stasis constitutional medicine formula food according to claim 1, is characterized in that described small peptide is: marine collagen peptide, maize oligopeptide, wheat oligopeptide, sea bone peptide, Soyprotein peptide, whey protein peptide, ovalbumin peptide are wherein a kind of, several or all mix.