CN104245736B - 抗人死亡受体5胞外区的人源化单克隆抗体 - Google Patents
抗人死亡受体5胞外区的人源化单克隆抗体 Download PDFInfo
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| Application Number | Priority Date | Filing Date | Title |
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| PCT/CN2012/083627 WO2014063368A1 (fr) | 2012-10-26 | 2012-10-26 | Anticorps monoclonal humanisé dans un domaine extracellulaire de l'anti-récepteur de mort humain 5 |
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| CN104245736A CN104245736A (zh) | 2014-12-24 |
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| CN201280072668.6A Active CN104245736B (zh) | 2012-10-26 | 2012-10-26 | 抗人死亡受体5胞外区的人源化单克隆抗体 |
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| Country | Link |
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| US (1) | US9725517B2 (fr) |
| CN (1) | CN104245736B (fr) |
| WO (1) | WO2014063368A1 (fr) |
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| KR102435324B1 (ko) | 2015-01-20 | 2022-08-23 | 아이쥐엠 바이오사이언스 인코포레이티드 | 종양 괴사 인자(ｔｎｆ) 수퍼패밀리 수용체 결합 분자 및 그의 용도 |
| CA3003033A1 (fr) * | 2015-10-30 | 2017-05-04 | Galaxy Biotech, Llc | Anticorps hautement puissants se liant au recepteur de mort 4 et au recepteur de mort 5 |
| BR112018076247A2 (pt) * | 2016-06-16 | 2019-03-26 | The Board Of Trustees Of The Leland Stanford Junior University | anticorpos monoclonais quiméricos e humanizados para cd81 |
| KR101926834B1 (ko) * | 2017-03-21 | 2018-12-07 | 동아에스티 주식회사 | 항-dr5 항체 및 그의 용도 |
| US11230592B2 (en) | 2017-09-27 | 2022-01-25 | The Wistar Institute Of Anatomy And Biology | DNA antibody constructs for use against middle east respiratory syndrome coronavirus |
| CN109957024A (zh) * | 2017-12-25 | 2019-07-02 | 深圳宾德生物技术有限公司 | 一种靶向dr5的单链抗体、嵌合抗原受体t细胞及其制备方法和应用 |
| WO2019157772A1 (fr) * | 2018-02-13 | 2019-08-22 | 和元生物技术（上海）股份有限公司 | Conjugué anticorps anti-trailr2-toxine et son utilisation pharmaceutique en thérapie antitumorale |
| CN110152014B (zh) * | 2018-02-13 | 2022-09-27 | 烟台市和元艾迪斯生物医药科技有限公司 | 抗trailr2抗体-毒素-偶联物及其在抗肿瘤治疗中的药物用途 |
| CN110141666B (zh) * | 2018-02-13 | 2022-09-27 | 烟台市和元艾迪斯生物医药科技有限公司 | 抗trailr2抗体-毒素-偶联物及其在抗肿瘤治疗中的药物用途 |
| CN108452320B (zh) * | 2018-02-13 | 2020-04-10 | 烟台市和元艾迪斯生物医药科技有限公司 | 抗trailr2抗体-毒素-偶联物及其在抗肿瘤治疗中的药物用途 |
| CN115819587B (zh) * | 2022-10-14 | 2023-06-09 | 北京东方百泰生物科技股份有限公司 | 一种抗nkg2a单克隆抗体及其应用 |
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| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| CN100427505C (zh) * | 2004-08-19 | 2008-10-22 | 中国医学科学院基础医学研究所 | 抗人肿瘤坏死因子相关凋亡诱导配体的受体dr5单克隆抗体（ad5-10）及其制法与用途 |
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- 2012-10-26 CN CN201280072668.6A patent/CN104245736B/zh active Active
- 2012-10-26 WO PCT/CN2012/083627 patent/WO2014063368A1/fr active Application Filing
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| Publication number | Publication date |
|---|---|
| CN104245736A (zh) | 2014-12-24 |
| US9725517B2 (en) | 2017-08-08 |
| US20150353638A1 (en) | 2015-12-10 |
| WO2014063368A1 (fr) | 2014-05-01 |
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