CN104245094A - 分子分离装置 - Google Patents

分子分离装置 Download PDF

Info

Publication number
CN104245094A
CN104245094A CN201380014845.XA CN201380014845A CN104245094A CN 104245094 A CN104245094 A CN 104245094A CN 201380014845 A CN201380014845 A CN 201380014845A CN 104245094 A CN104245094 A CN 104245094A
Authority
CN
China
Prior art keywords
separation membrane
membrane
charge
periphery
components
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201380014845.XA
Other languages
English (en)
Chinese (zh)
Inventor
小约翰·B·斯特森
莎拉·西蒙
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lockheed Martin Corp
Original Assignee
Lockheed Martin Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lockheed Martin Corp filed Critical Lockheed Martin Corp
Priority to CN201710120140.6A priority Critical patent/CN106823846A/zh
Publication of CN104245094A publication Critical patent/CN104245094A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/24—Extraction; Separation; Purification by electrochemical means
    • C07K1/26—Electrophoresis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D57/00—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C
    • B01D57/02—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C by electrophoresis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D35/00—Filtering devices having features not specifically covered by groups B01D24/00 - B01D33/00, or for applications not specifically covered by groups B01D24/00 - B01D33/00; Auxiliary devices for filtration; Filter housing constructions
    • B01D35/06—Filters making use of electricity or magnetism
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/02—Inorganic material
    • B01D71/021—Carbon
    • B01D71/0211—Graphene or derivates thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/20—Specific permeability or cut-off range
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/18—Apparatus therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Electrochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Environmental & Geological Engineering (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Urology & Nephrology (AREA)
  • Electrostatic Separation (AREA)
  • Peptides Or Proteins (AREA)
CN201380014845.XA 2012-03-21 2013-03-20 分子分离装置 Pending CN104245094A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710120140.6A CN106823846A (zh) 2012-03-21 2013-03-20 分子分离装置

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261613578P 2012-03-21 2012-03-21
US61/613,578 2012-03-21
PCT/US2013/033035 WO2013142539A1 (en) 2012-03-21 2013-03-20 Molecular separation device

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201710120140.6A Division CN106823846A (zh) 2012-03-21 2013-03-20 分子分离装置

Publications (1)

Publication Number Publication Date
CN104245094A true CN104245094A (zh) 2014-12-24

Family

ID=48050312

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201710120140.6A Pending CN106823846A (zh) 2012-03-21 2013-03-20 分子分离装置
CN201380014845.XA Pending CN104245094A (zh) 2012-03-21 2013-03-20 分子分离装置

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN201710120140.6A Pending CN106823846A (zh) 2012-03-21 2013-03-20 分子分离装置

Country Status (12)

Country Link
US (2) US9028663B2 (enExample)
EP (1) EP2827974A1 (enExample)
JP (2) JP2015511531A (enExample)
KR (1) KR20140147855A (enExample)
CN (2) CN106823846A (enExample)
AU (2) AU2013235234A1 (enExample)
CA (1) CA2865648A1 (enExample)
IL (1) IL234685A0 (enExample)
IN (1) IN2014DN07731A (enExample)
SA (1) SA113340401B1 (enExample)
SG (1) SG11201405347PA (enExample)
WO (1) WO2013142539A1 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9475709B2 (en) 2010-08-25 2016-10-25 Lockheed Martin Corporation Perforated graphene deionization or desalination
US9193587B2 (en) 2011-07-13 2015-11-24 Lockheed Martin Corporation System and method for water purification and desalination
KR20140146131A (ko) 2012-03-21 2014-12-24 록히드 마틴 코포레이션 활성화 가스 스트림을 사용하여 그래핀을 천공하기 위한 방법들 및 그것으로부터 제조되는 천공된 그래핀
US9463421B2 (en) 2012-03-29 2016-10-11 Lockheed Martin Corporation Planar filtration and selective isolation and recovery device
US9095823B2 (en) * 2012-03-29 2015-08-04 Lockheed Martin Corporation Tunable layered membrane configuration for filtration and selective isolation and recovery devices
US9744617B2 (en) 2014-01-31 2017-08-29 Lockheed Martin Corporation Methods for perforating multi-layer graphene through ion bombardment
US10980919B2 (en) 2016-04-14 2021-04-20 Lockheed Martin Corporation Methods for in vivo and in vitro use of graphene and other two-dimensional materials
US9834809B2 (en) 2014-02-28 2017-12-05 Lockheed Martin Corporation Syringe for obtaining nano-sized materials for selective assays and related methods of use
US9067811B1 (en) * 2012-05-25 2015-06-30 Lockheed Martin Corporation System, method, and control for graphenoid desalination
US10653824B2 (en) 2012-05-25 2020-05-19 Lockheed Martin Corporation Two-dimensional materials and uses thereof
US9610546B2 (en) 2014-03-12 2017-04-04 Lockheed Martin Corporation Separation membranes formed from perforated graphene and methods for use thereof
US9870895B2 (en) 2014-01-31 2018-01-16 Lockheed Martin Corporation Methods for perforating two-dimensional materials using a broad ion field
US9592475B2 (en) 2013-03-12 2017-03-14 Lockheed Martin Corporation Method for forming perforated graphene with uniform aperture size
EP2969153A1 (en) 2013-03-13 2016-01-20 Lockheed Martin Corporation Nanoporous membranes and methods for making the same
US9480952B2 (en) 2013-03-14 2016-11-01 Lockheed Martin Corporation Methods for chemical reaction perforation of atomically thin materials
US9572918B2 (en) * 2013-06-21 2017-02-21 Lockheed Martin Corporation Graphene-based filter for isolating a substance from blood
SG11201606287VA (en) 2014-01-31 2016-08-30 Lockheed Corp Processes for forming composite structures with a two-dimensional material using a porous, non-sacrificial supporting layer
WO2015138808A1 (en) * 2014-03-12 2015-09-17 Lockheed Martin Corporation Graphene-based molecular separation and sequestration device
CA2942496A1 (en) 2014-03-12 2015-09-17 Lockheed Martin Corporation Separation membranes formed from perforated graphene
AU2015229296A1 (en) * 2014-03-12 2016-10-27 Lockheed Martin Corporation In vivo and in vitro use of graphene
AU2015311978A1 (en) 2014-09-02 2017-05-11 Lockheed Martin Corporation Hemodialysis and hemofiltration membranes based upon a two-dimensional membrane material and methods employing same
EP3253429A2 (en) * 2015-02-06 2017-12-13 Cabot Corporation Urea sequestration compositions and methods
WO2017023376A1 (en) 2015-08-05 2017-02-09 Lockheed Martin Corporation Perforatable sheets of graphene-based material
WO2017023377A1 (en) 2015-08-06 2017-02-09 Lockheed Martin Corporation Nanoparticle modification and perforation of graphene
KR20180133430A (ko) 2016-04-14 2018-12-14 록히드 마틴 코포레이션 결함 형성 또는 힐링의 인 시츄 모니터링 및 제어를 위한 방법
WO2017180139A1 (en) 2016-04-14 2017-10-19 Lockheed Martin Corporation Two-dimensional membrane structures having flow passages
WO2017180135A1 (en) 2016-04-14 2017-10-19 Lockheed Martin Corporation Membranes with tunable selectivity
CA3020880A1 (en) 2016-04-14 2017-10-19 Lockheed Martin Corporation Selective interfacial mitigation of graphene defects
JP2019511451A (ja) 2016-04-14 2019-04-25 ロッキード・マーチン・コーポレーション 浮遊法を用いてグラフェンシートを大判転写用に処理する方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040142463A1 (en) * 2001-10-11 2004-07-22 George Walker Methods, compositions, and automated systems for separating rare cells from fluid samples
US20100327847A1 (en) * 2007-09-12 2010-12-30 President And Fellows Of Harvard College High-Resolution Molecular Sensor
CN102242062A (zh) * 2011-04-19 2011-11-16 浙江大学 一种高分辨率的生物传感器
US20120048804A1 (en) * 2010-08-25 2012-03-01 Lockheed Martin Corporation Perforated graphene deionization or desalination

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA26028A1 (fr) 1997-01-09 2004-04-01 Garfield Int Invest Ltd Dessalement de l'eau
GB0100513D0 (en) 2001-01-09 2001-02-21 Smithkline Beecham Plc Process
JP3939943B2 (ja) 2001-08-29 2007-07-04 株式会社Ｇｓｉクレオス 気相成長法による炭素繊維からなるフィルター材
AU2003267094A1 (en) * 2002-09-11 2004-04-30 Temple University - Of The Commonwealth System Of Higher Education System and methods for electrophoretic separation of proteins on protein binding membranes
US7150813B2 (en) * 2003-06-12 2006-12-19 Palo Alto Research Center Incorporated Isoelectric focusing (IEF) of proteins with sequential and oppositely directed traveling waves in gel electrophoresis
US7410574B2 (en) 2004-03-03 2008-08-12 Patent Innovations Llc Magnetic particle filtration apparatus
DE102004062535A1 (de) 2004-12-24 2006-07-06 Forschungszentrum Karlsruhe Gmbh Semipermeables Membransystem für magnetische Partikelfraktionen
DE102005012594A1 (de) * 2005-03-18 2006-09-21 Bayer Technology Services Gmbh Elektrofiltrationsverfahren
US20100059378A1 (en) 2007-07-18 2010-03-11 The Water Company Llc Apparatus and method for removal of ions from a porous electrode that is part of a deionization system
US8409450B2 (en) * 2008-03-24 2013-04-02 The Regents Of The University Of California Graphene-based structure, method of suspending graphene membrane, and method of depositing material onto graphene membrane
US8147599B2 (en) 2009-02-17 2012-04-03 Mcalister Technologies, Llc Apparatuses and methods for storing and/or filtering a substance
EP2230511B1 (en) 2009-03-20 2017-04-26 Ecole Polytechnique Method for varying the diameter of a nanopore contained in a nanoporous membrane functionalised with a ph-dependent polyelectrolyte
EP2464446B1 (en) 2009-08-10 2014-12-24 Danisco US Inc. Cross-flow membrane filtration-based process for protein recovery
US8292092B2 (en) * 2009-09-08 2012-10-23 Teledyne Scientific & Imaging, Llc Macrocyclic pore-apertured carbon nanotube apparatus
CA2772789C (en) * 2009-09-18 2018-10-30 President And Fellows Of Harvard College Bare single-layer graphene membrane having a nanopore enabling high-sensitivity molecular detection and analysis
WO2011063458A1 (en) 2009-11-25 2011-06-03 University Of Sydney Membrane and membrane separation system
AU2011279530A1 (en) 2010-07-14 2013-01-31 Monash University Material and applications therefor
CA2806399A1 (en) * 2010-07-28 2012-02-02 Smartcells, Inc. Recombinantly expressed insulin polypeptides and uses thereof
US9475709B2 (en) * 2010-08-25 2016-10-25 Lockheed Martin Corporation Perforated graphene deionization or desalination
WO2012030368A1 (en) 2010-09-01 2012-03-08 Lawrence Curtin Application of radio frequency to fluidized beds
KR101211850B1 (ko) 2010-09-01 2012-12-12 연세대학교 산학협력단 그라핀 나노 필터 망, 그라핀 나노 필터 및 그 제조방법
US9056282B2 (en) * 2012-01-27 2015-06-16 Empire Technology Development Llc Accelerating transport through graphene membranes
US11135546B2 (en) * 2012-03-15 2021-10-05 Massachusetts Institute Of Technology Graphene based filter
KR20140146131A (ko) * 2012-03-21 2014-12-24 록히드 마틴 코포레이션 활성화 가스 스트림을 사용하여 그래핀을 천공하기 위한 방법들 및 그것으로부터 제조되는 천공된 그래핀
US9067811B1 (en) * 2012-05-25 2015-06-30 Lockheed Martin Corporation System, method, and control for graphenoid desalination
US9610546B2 (en) * 2014-03-12 2017-04-04 Lockheed Martin Corporation Separation membranes formed from perforated graphene and methods for use thereof
US9592475B2 (en) * 2013-03-12 2017-03-14 Lockheed Martin Corporation Method for forming perforated graphene with uniform aperture size
US9572918B2 (en) * 2013-06-21 2017-02-21 Lockheed Martin Corporation Graphene-based filter for isolating a substance from blood
WO2015077751A1 (en) * 2013-11-25 2015-05-28 Northeastern University Freestanding ultra thin membranes and transfer-free fabrication thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040142463A1 (en) * 2001-10-11 2004-07-22 George Walker Methods, compositions, and automated systems for separating rare cells from fluid samples
US20100327847A1 (en) * 2007-09-12 2010-12-30 President And Fellows Of Harvard College High-Resolution Molecular Sensor
US20120048804A1 (en) * 2010-08-25 2012-03-01 Lockheed Martin Corporation Perforated graphene deionization or desalination
CN102242062A (zh) * 2011-04-19 2011-11-16 浙江大学 一种高分辨率的生物传感器

Also Published As

Publication number Publication date
CA2865648A1 (en) 2013-09-26
IN2014DN07731A (enExample) 2015-05-15
JP2015511531A (ja) 2015-04-20
US20130248367A1 (en) 2013-09-26
SG11201405347PA (en) 2014-10-30
US9028663B2 (en) 2015-05-12
IL234685A0 (en) 2014-11-30
CN106823846A (zh) 2017-06-13
AU2018200090A1 (en) 2018-01-25
KR20140147855A (ko) 2014-12-30
US20150218210A1 (en) 2015-08-06
JP2017100127A (ja) 2017-06-08
SA113340401B1 (ar) 2015-08-16
AU2013235234A1 (en) 2014-10-16
WO2013142539A1 (en) 2013-09-26
EP2827974A1 (en) 2015-01-28

Similar Documents

Publication Publication Date Title
CN104245094A (zh) 分子分离装置
US10005038B2 (en) Hemodialysis and hemofiltration membranes based upon a two-dimensional membrane material and methods employing same
US20160339160A1 (en) Two-dimensional materials and uses thereof
US10980919B2 (en) Methods for in vivo and in vitro use of graphene and other two-dimensional materials
WO2017180135A1 (en) Membranes with tunable selectivity
KR101726286B1 (ko) 세포외 소포체 포집 장치 및 그 사용 방법
EP3442786A1 (en) Two-dimensional membrane structures having flow passages
EP3225296A1 (en) Hybrid liquid filter structure
KR102235424B1 (ko) 역침투막 장치 및 그 운전 방법
CN214654867U (zh) 分离芯片及分离装置
CN107446797A (zh) 外泌体处理芯片及处理方法
CN206027245U (zh) 一种微米及亚微米级颗粒离心式过滤收集的控制结构
CN104568561A (zh) 一种蛋白质核酸分离装置和方法
JP6452049B2 (ja) 円形断面を有する流路で構成される流動分別型孔拡散膜分離用モジュール。
JP2012029676A (ja) 核酸濃縮回収用カートリッジ、核酸濃縮回収方法、及び該カートリッジの製造方法
CN105363349A (zh) 一种均一孔径滤膜的制备方法
JP6534068B2 (ja) 高分子溶液中の成分分子を分画する孔拡散膜分離用モジュール
US11767241B2 (en) Device for purifying fluid using ion concentration polarization phenomenon and purification system
JP6052384B2 (ja) 核酸濃縮回収用カートリッジ、核酸濃縮回収方法、及び該カートリッジの製造方法
KR101549850B1 (ko) 바이러스 하이브리드 분리막 및 이의 제조방법
Gavalas Filtering apparatus and method of use
WO2019152476A1 (en) Pulse-modulated periodic backflush for clearance of fouling layers in dead-end filtration systems
CN1634136A (zh) 用于血制品生产中去除脂质体及病素的方法及装置
KR20140141361A (ko) 다공성 구조체 및 그의 제조 방법, 상기 다공성 구조체를 포함하는 분리막, 및 상기 분리막을 포함하는 수처리 장치

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20141224

WD01 Invention patent application deemed withdrawn after publication