CN104244966B - 水母发光蛋白用于减少缺血导致的神经损伤 - Google Patents
水母发光蛋白用于减少缺血导致的神经损伤 Download PDFInfo
- Publication number
- CN104244966B CN104244966B CN201280066993.1A CN201280066993A CN104244966B CN 104244966 B CN104244966 B CN 104244966B CN 201280066993 A CN201280066993 A CN 201280066993A CN 104244966 B CN104244966 B CN 104244966B
- Authority
- CN
- China
- Prior art keywords
- aequorin
- injection
- composition
- cell
- ischemic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1767—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161559816P | 2011-11-15 | 2011-11-15 | |
| US61/559,816 | 2011-11-15 | ||
| PCT/US2012/065291 WO2013074798A1 (en) | 2011-11-15 | 2012-11-15 | Apoaequorin for reducing neuronal injury due to ischemia |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104244966A CN104244966A (zh) | 2014-12-24 |
| CN104244966B true CN104244966B (zh) | 2019-01-11 |
Family
ID=47295186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201280066993.1A Active CN104244966B (zh) | 2011-11-15 | 2012-11-15 | 水母发光蛋白用于减少缺血导致的神经损伤 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20140294874A1 (https=) |
| EP (1) | EP2780027B1 (https=) |
| JP (1) | JP6181061B2 (https=) |
| KR (1) | KR102009932B1 (https=) |
| CN (1) | CN104244966B (https=) |
| AU (1) | AU2012340446B2 (https=) |
| BR (1) | BR112014011630A2 (https=) |
| CA (1) | CA2855719C (https=) |
| CY (1) | CY1119300T1 (https=) |
| DK (1) | DK2780027T3 (https=) |
| ES (1) | ES2643392T3 (https=) |
| HR (1) | HRP20171532T1 (https=) |
| HU (1) | HUE035017T2 (https=) |
| IL (1) | IL232494B (https=) |
| IN (1) | IN2014CN04009A (https=) |
| LT (1) | LT2780027T (https=) |
| MX (1) | MX350259B (https=) |
| PL (1) | PL2780027T3 (https=) |
| PT (1) | PT2780027T (https=) |
| SG (1) | SG11201402364WA (https=) |
| SI (1) | SI2780027T1 (https=) |
| WO (1) | WO2013074798A1 (https=) |
| ZA (1) | ZA201403577B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA40959A (fr) * | 2014-11-11 | 2017-09-19 | Quincy Bioscience Llc | Compositions contenant de l'apoaéquorine et leurs procédés d'utilisation pour traiter l'inflammation neuronale |
| KR20180001229A (ko) | 2016-06-27 | 2018-01-04 | 삼성에스디아이 주식회사 | 이차 전지의 제조 방법 및 이를 이용한 이차 전지 |
| SI3515212T1 (sl) * | 2016-09-23 | 2024-10-30 | Quincy Bioscience Llc | Sestavki, ki vsebujejo apoaequorin in vitamin d, ter načini njihove uporabe |
| RU2642961C1 (ru) * | 2017-02-21 | 2018-01-29 | Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") | Способ профилактики ишемии головного мозга |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101437845A (zh) * | 2006-02-15 | 2009-05-20 | 莫沃斯技术有限公司 | 细胞凋亡的方法、基因和蛋白 |
| US20110130336A1 (en) * | 2009-10-16 | 2011-06-02 | Quincy Bioscience, Llc | Method of treating ischemic injury using apoaequorin |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060229243A1 (en) * | 2004-06-21 | 2006-10-12 | Quincy Resource Group, Inc. | Aequorin-containing compositions and methods of using same |
| BRPI0909435A2 (pt) * | 2008-03-11 | 2017-06-13 | Quincy Bioscience Llc | composição e método para tratar de um sintoma ou distúrbio associado com o desequilíbrio do cálcio, uso da apoequorina, e, apoaequorina |
| JP5919604B2 (ja) * | 2008-08-08 | 2016-05-18 | イミューノメディクス、インコーポレイテッドImmunomedics, Inc. | 抗膵癌抗体 |
-
2012
- 2012-11-15 KR KR1020147016261A patent/KR102009932B1/ko active Active
- 2012-11-15 LT LTEP12795955.9T patent/LT2780027T/lt unknown
- 2012-11-15 SI SI201231064T patent/SI2780027T1/sl unknown
- 2012-11-15 BR BR112014011630A patent/BR112014011630A2/pt not_active Application Discontinuation
- 2012-11-15 DK DK12795955.9T patent/DK2780027T3/en active
- 2012-11-15 AU AU2012340446A patent/AU2012340446B2/en active Active
- 2012-11-15 IN IN4009CHN2014 patent/IN2014CN04009A/en unknown
- 2012-11-15 WO PCT/US2012/065291 patent/WO2013074798A1/en not_active Ceased
- 2012-11-15 MX MX2014005798A patent/MX350259B/es active IP Right Grant
- 2012-11-15 PL PL12795955T patent/PL2780027T3/pl unknown
- 2012-11-15 US US14/358,274 patent/US20140294874A1/en not_active Abandoned
- 2012-11-15 SG SG11201402364WA patent/SG11201402364WA/en unknown
- 2012-11-15 CA CA2855719A patent/CA2855719C/en active Active
- 2012-11-15 JP JP2014542463A patent/JP6181061B2/ja active Active
- 2012-11-15 HU HUE12795955A patent/HUE035017T2/en unknown
- 2012-11-15 HR HRP20171532TT patent/HRP20171532T1/hr unknown
- 2012-11-15 ES ES12795955.9T patent/ES2643392T3/es active Active
- 2012-11-15 EP EP12795955.9A patent/EP2780027B1/en active Active
- 2012-11-15 CN CN201280066993.1A patent/CN104244966B/zh active Active
- 2012-11-15 PT PT127959559T patent/PT2780027T/pt unknown
-
2014
- 2014-05-07 IL IL232494A patent/IL232494B/en active IP Right Grant
- 2014-05-16 ZA ZA2014/03577A patent/ZA201403577B/en unknown
-
2017
- 2017-08-08 CY CY20171100851T patent/CY1119300T1/el unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101437845A (zh) * | 2006-02-15 | 2009-05-20 | 莫沃斯技术有限公司 | 细胞凋亡的方法、基因和蛋白 |
| US20110130336A1 (en) * | 2009-10-16 | 2011-06-02 | Quincy Bioscience, Llc | Method of treating ischemic injury using apoaequorin |
Also Published As
| Publication number | Publication date |
|---|---|
| BR112014011630A2 (pt) | 2017-06-27 |
| DK2780027T3 (en) | 2017-09-25 |
| IL232494B (en) | 2019-03-31 |
| LT2780027T (lt) | 2017-10-25 |
| HUE035017T2 (en) | 2018-03-28 |
| HK1202417A1 (en) | 2015-10-02 |
| ZA201403577B (en) | 2015-07-29 |
| NZ624736A (en) | 2016-05-27 |
| SG11201402364WA (en) | 2014-09-26 |
| EP2780027B1 (en) | 2017-07-19 |
| MX350259B (es) | 2017-08-31 |
| AU2012340446B2 (en) | 2017-08-31 |
| IL232494A0 (en) | 2014-06-30 |
| US20140294874A1 (en) | 2014-10-02 |
| HRP20171532T1 (hr) | 2017-11-17 |
| CY1119300T1 (el) | 2018-02-14 |
| CA2855719A1 (en) | 2013-05-23 |
| ES2643392T3 (es) | 2017-11-22 |
| KR102009932B1 (ko) | 2019-08-12 |
| AU2012340446A1 (en) | 2014-05-29 |
| PL2780027T3 (pl) | 2017-11-30 |
| CA2855719C (en) | 2021-10-26 |
| JP6181061B2 (ja) | 2017-08-16 |
| JP2014533692A (ja) | 2014-12-15 |
| EP2780027A1 (en) | 2014-09-24 |
| PT2780027T (pt) | 2017-10-04 |
| KR20140097369A (ko) | 2014-08-06 |
| CN104244966A (zh) | 2014-12-24 |
| SI2780027T1 (sl) | 2017-11-30 |
| MX2014005798A (es) | 2014-05-30 |
| WO2013074798A1 (en) | 2013-05-23 |
| IN2014CN04009A (https=) | 2015-10-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20250319 Address after: texas Patentee after: Jingshui Bioscience Group Co.,Ltd. Country or region after: U.S.A. Address before: Wisconsin Patentee before: Quincy Bioscience, LLC Country or region before: U.S.A. |
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| TR01 | Transfer of patent right |