CN104215629A - Development and production of test paper for rapid testing of aldehyde disinfectant concentration - Google Patents
Development and production of test paper for rapid testing of aldehyde disinfectant concentration Download PDFInfo
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- CN104215629A CN104215629A CN201310220855.0A CN201310220855A CN104215629A CN 104215629 A CN104215629 A CN 104215629A CN 201310220855 A CN201310220855 A CN 201310220855A CN 104215629 A CN104215629 A CN 104215629A
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Abstract
The invention relates to a test card (except glutaraldehyde) for determining the aldehyde concentration of an-aldehyde containing disinfection solution. Aldehydes have the important property that: aldehydes can react with sulfite to generate a colorless or white precipitate, and at the same time, aldehydes react with amino acids to be yellow. Through testes, sulfite and amino acids are selected, the ratio and concentration of the two are adjusted to prepare a mother liquor, then test paper is treated, the treated test paper further adsorbs a certain amount of stabilizer, drying or natural drying is conducted, then shear molding is carried out, and the test paper is fixed on a nonabsorbent base material by an appropriate method, thus obtaining the aldehyde disinfectant concentration test card, and simultaneously a standard color card can be printed on the test card or used individually. By accurate control and regulation of the mother liquor components and treatment conditions, series of test cards sensitive to different concentration ranges can be prepared to test the concentration of aldehyde disinfectants with different aldehydes and different concentration ranges.
Description
Technical field
The invention belongs to disinfecting medicine field, relate to the quick test paper of aldehyde disinfectant (except glutaraldehyde) concentration.
Background technology
Aldehyde disinfectant is widely used in Medical instrument sterilization sterilizing, but in sterilization process, aldehyde disinfectant is constantly consumed, when its concentration is during lower than limit value, within the equal processing time, bactericidal effect is difficult to guarantee, the necessary corresponding prolongation processing time, so, medical institutions need the concentration of often measuring aldehyde disinfectant to guarantee bactericidal effect, the existing useful titration measuring of document, but because of the difference of filling a prescription, to measurement result, disturb very large, often be not used, now more classical is with gas chromatography determination, but because of too loaded down with trivial details, time cost is long, higher to equipment and technical requirement, general different medical unit is limit by condition does not have condition.And adopt aldehyde disinfectant concentration test card of the present invention can directly measure rapidly the concentration range of all kinds of aldehyde disinfectants, its Disinfection Effect is made to objective evaluation.
There is in the market the glutaraldehyde concentration testing card of measuring more simply and rapidly glutaraldehyde concentration, as the glutaraldehyde concentration testing card of Minnesota Mining and Manufacturing Company, and Wuhan Kang Weida health care product company limited and Beijing join the glutaraldehyde concentration testing card that prosperous disinfecting articles for use company limited produces, the patent of declaring has: glutaraldehyde concentration testing card (patent publication No.: CN1477368A), concentration test card (is authorized publication number: CN2702305Y) etc., above several patents are only used for glutaraldehyde concentration test.
We find that the present invention can be suitable for all aldehyde disinfectants under study for action, cut the reagent scope that reagent of the present invention also uses than above glutaraldehyde concentration testing card and expand to some extent.Because the present invention has part principle identical with published patent, so the concentration determination that we are the aldehyde-containing type sanitizer except glutaraldehyde by our usable range regulation.
Summary of the invention
In order to measure intuitively rapidly the concentration range of aldehyde disinfectant, guarantee the Disinfection Effect of sanitizer, we have developed aldehyde disinfectant concentration test card.Aldehyde compound has a critical nature: aldehydes can generate colourless or white precipitate with sulphite reaction, and aldehydes reacts and displaing yellow with amino acids simultaneously.We are through overtesting, select sulphite and amino acids, regulate the two ratio and concentration, make mother liquor, then process test paper, treated test paper adsorbs a certain amount of stabilizing agent again, drying or natural drying, then shear forming, by suitable method, be fixed on the ground not absorbing water, can obtain aldehyde disinfectant concentration test card, also standard color card can be imprinted on test card, or use separately simultaneously.Accurately control and regulate mother liquor composition and treatment conditions, can make the series of tests card to variable concentrations range-sensitive, for testing the aldehyde disinfectant concentration of different aldehydes, variable concentrations scope.During test, only test card evenly adhesional wetting rapidly in wanting to record aldehyde disinfectant solution need be crossed to the change color of 5 ~ 8 minutes observable test cards, according to the variation of color or with prior specified standard colour atla, relatively judge the concentration range of surveyed aldehyde disinfectant.This method is easy and simple to handle, and result is also more accurate, can meet the requirement to aldehyde disinfectant concentration precision clinically completely, and to operator without any special technical requirement, can intuitively to the sterilization situation of aldehyde disinfectant used, assess rapidly.
Embodiment
1, sodium sulphite 0.12604g
Lysine 7.3095g
PH damping fluid 10ml
Purified water is appropriate
100ml processed altogether
2, potassium sulfite 0.15826g
Glycocoll 3.7535g
PH damping fluid 10ml
Purified water is appropriate
100ml processed altogether
3, sodium sulphite 0.12604g
Glycocoll 3.7535g
PH damping fluid 10ml
Purified water is appropriate
100ml processed altogether
4, potassium sulfite 0.15826g
Lysine 7.3095g
PH damping fluid 10ml
Purified water is appropriate
100ml processed altogether
The test solution preparing is placed 24 hours, the test paper of the suitable size of cutting out is immersed in this solution completely, make the chemical composition in the even absorbent solution of test paper energy, soak after 24 hours, test paper is taken out, oven dry or natural drying at 40 ℃, after test paper bone dry, test paper adopts suitable method to be fixed on the ground not absorbing water.So just can make the concentration test card of aldehyde disinfectant.During use with in test card adhesional wetting 4 ~ 8 minutes by the even flavescence of white; When aldehyde disinfectant concentration does not reach while requiring limit, only there is part flavescence, inhomogeneous flavescence or nondiscolouring in 4 ~ 8 minutes in test card adhesional wetting.For the standard color card of preparing in advance easy to use, after colour developing, with standard color card, contrast, get final product judged result.
Claims (8)
1. the aldehyde disinfectant described in is other all aldehyde disinfectants except glutaraldehyde; As: o-phthalaldehyde(OPA) etc.
2. the described quick test paper of aldehyde disinfectant concentration of claim 1, is characterized in that by test paper, standard color card through special processing or does not have standard color card to form.
3. the described test paper of claim 2, through special processing, is characterized in that test paper is used sulfite solution and Freamine Ⅲ and stabilizer treatment test paper; Sulphite wherein, mainly comprises: sodium sulphite, potassium sulfite, calcium sulfite, sodium bisulfite, potassium bisulfite, sodium pyrosulfite, and potassium metabisulfite etc., its concentration range is: 0.001～2mol/L.
4. the described amino acid of claim 3, mainly comprises: the amino acid such as glycocoll, lysine, threonine, tryptophane, phenylalanine; Amino acid whose concentration range is: 0.01～2mol/L.
5. stabilizing agent claimed in claim 3 refers to by wherein one or more such as pH damping fluid, complexing agent, antioxidant and forms.
6. the described test paper of claim 3 is through special processing, mainly dry after dry after above-mentioned several test solutions soak or several test solution mixed liquid dippings respectively; Baking temperature is: 5～100 ℃..
7. the described test paper of claim 3 is through test solution special processing, and the test solution kind of using is different, will directly cause the difference of result; Can be by regulating the concentration of various test solutions to reach the object of the variable concentrations of the different aldehyde disinfectants of test.
8. by observing the variation of test paper color, determine the concentration range of aldehyde disinfectant.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310220855.0A CN104215629A (en) | 2013-06-05 | 2013-06-05 | Development and production of test paper for rapid testing of aldehyde disinfectant concentration |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310220855.0A CN104215629A (en) | 2013-06-05 | 2013-06-05 | Development and production of test paper for rapid testing of aldehyde disinfectant concentration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104215629A true CN104215629A (en) | 2014-12-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN201310220855.0A Pending CN104215629A (en) | 2013-06-05 | 2013-06-05 | Development and production of test paper for rapid testing of aldehyde disinfectant concentration |
Country Status (1)
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104376763A (en) * | 2014-11-11 | 2015-02-25 | 李长久 | Atmospheric pressure and vacuum suction presentation device for teaching experiments |
| CN104677904A (en) * | 2015-02-04 | 2015-06-03 | 北京红辉力上科技有限公司 | Test paper for testing concentration of ortho-phthalaldehyde disinfectant |
| CN106872459A (en) * | 2017-03-06 | 2017-06-20 | 亳州市新健康科技有限公司 | A kind of OPA thimerosal and Concentration Testing test paper and manufacture craft |
| CN106970078A (en) * | 2017-05-15 | 2017-07-21 | 北京长江脉医药科技有限责任公司 | A kind of test paper and its preparation and detection method for detecting OPA |
| CN106970075A (en) * | 2017-03-20 | 2017-07-21 | 广西庆荣卫生消毒制品有限公司 | A kind of OPA Concentration Testing test paper and preparation method thereof |
| CN107024473A (en) * | 2017-05-15 | 2017-08-08 | 北京长江脉医药科技有限责任公司 | A kind of O-phthalaldehyde disinfectant concentration quick detection test paper and preparation method and application |
| CN111024687A (en) * | 2019-12-23 | 2020-04-17 | 广东环凯微生物科技有限公司 | Glutaraldehyde determination test paper and rapid determination method |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1160569A2 (en) * | 2000-05-30 | 2001-12-05 | Integrated Biomedical Technology, Inc. | Assay for aldehyde content |
| CN1477386A (en) * | 2002-08-19 | 2004-02-25 | 杨 柳 | Glutaraldehyde concentration testing card |
| CN2702305Y (en) * | 2004-05-12 | 2005-05-25 | 梁建生 | Concentration test card |
-
2013
- 2013-06-05 CN CN201310220855.0A patent/CN104215629A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1160569A2 (en) * | 2000-05-30 | 2001-12-05 | Integrated Biomedical Technology, Inc. | Assay for aldehyde content |
| CN1477386A (en) * | 2002-08-19 | 2004-02-25 | 杨 柳 | Glutaraldehyde concentration testing card |
| CN2702305Y (en) * | 2004-05-12 | 2005-05-25 | 梁建生 | Concentration test card |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104376763A (en) * | 2014-11-11 | 2015-02-25 | 李长久 | Atmospheric pressure and vacuum suction presentation device for teaching experiments |
| CN104677904A (en) * | 2015-02-04 | 2015-06-03 | 北京红辉力上科技有限公司 | Test paper for testing concentration of ortho-phthalaldehyde disinfectant |
| CN106872459A (en) * | 2017-03-06 | 2017-06-20 | 亳州市新健康科技有限公司 | A kind of OPA thimerosal and Concentration Testing test paper and manufacture craft |
| CN106970075A (en) * | 2017-03-20 | 2017-07-21 | 广西庆荣卫生消毒制品有限公司 | A kind of OPA Concentration Testing test paper and preparation method thereof |
| CN106970078A (en) * | 2017-05-15 | 2017-07-21 | 北京长江脉医药科技有限责任公司 | A kind of test paper and its preparation and detection method for detecting OPA |
| CN107024473A (en) * | 2017-05-15 | 2017-08-08 | 北京长江脉医药科技有限责任公司 | A kind of O-phthalaldehyde disinfectant concentration quick detection test paper and preparation method and application |
| CN107024473B (en) * | 2017-05-15 | 2019-06-25 | 北京长江脉医药科技有限责任公司 | A kind of O-phthalaldehyde disinfectant concentration quick detection test paper and the preparation method and application thereof |
| CN111024687A (en) * | 2019-12-23 | 2020-04-17 | 广东环凯微生物科技有限公司 | Glutaraldehyde determination test paper and rapid determination method |
| CN111024687B (en) * | 2019-12-23 | 2022-03-25 | 广东环凯微生物科技有限公司 | Glutaraldehyde determination test paper and rapid determination method |
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Application publication date: 20141217 |