CN104189700A - Traditional Chinese medicine for treating senile dementia - Google Patents

Traditional Chinese medicine for treating senile dementia Download PDF

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Publication number
CN104189700A
CN104189700A CN201410491687.3A CN201410491687A CN104189700A CN 104189700 A CN104189700 A CN 104189700A CN 201410491687 A CN201410491687 A CN 201410491687A CN 104189700 A CN104189700 A CN 104189700A
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parts
grams
radix
rhizoma
fructus
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CN201410491687.3A
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Chinese (zh)
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李玉富
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Abstract

The invention discloses a traditional Chinese medicine for treating senile dementia. The traditional Chinese medicine is prepared from the following medicinal materials: fructus corni, epimedium herb, placenta hominis, abelmoschus sagittifolius merr, rhizoma curculiginis, Chinese wolfberry, shizandra berry, rhizoma acori Talarinowii, milkwort, roasted bombyx batryticatus, ligusticum wallichii, semen ziziphi spinosae, caulis polygoni multiflori, prepared rehmannia roots, rhizoma polygonati, fleeceflower roots, angelica sinensis, cistanche, radix salviae miltiorrhizae, radix puerariae, Chinese dodder seeds, raspberry, astragalus complanatus, cyperus rotundus, cratoneuron filicinum, rosemary, fenugreek, fructus psoraleae, Chinese yam, red paeony roots, radix astragali, codonopsis pilosula, beggiatoa mirabilis, dens draconis, rhizoma gastrodiae, lumbricus, peach kernel, poria with hostwood, parasitic loranthus, buckbean, Chinese mahonia leaves, actinidia arguta, raw fossil bone, raw oyster shell, alpinia oxyphylla, tenodera aridifolia stoll and rhizoma coptidis. The traditional Chinese medicine can be used for safely and effectively treating the senile dementia.

Description

A kind of Chinese medicine for the treatment of alzheimer disease
Technical field
The present invention relates to a kind of Chinese medicine, particularly a kind of Chinese medicine for the treatment of alzheimer disease.
Background technology
Alzheimer disease is a kind of nervous system degenerative disease that carries out sexual development of onset concealment.Show as feature with generalized dementias such as dysmnesia, aphasia, apraxia, agnosia, the infringement of visual space technical ability, execution dysfunction and personality and behavior changes clinically, the cause of disease is not bright so far.Within 65 years old, sent out in the past patient, claimed presenile dementia; Within 65 years old, claim alzheimer disease with sequela person.Slowly or concealment, when patient and household are often unable to explain clearly onset to this disease onset.Be more common in 70 years old above (average 73 years old of male, women is 75 years old) old man, a few patients symptom after physical disease, fracture or spirit are upset is clear rapidly.Women is compared with male many (female: man is 3: 1).Main manifestations is the decline gradually of decrease of cognitive function, mental symptom and behavior disorder, activity of daily living.Still lack at present the effective medicine of generally recognized as safe for alzheimer disease.
Summary of the invention
The problem to be solved in the present invention is: a kind of Chinese medicine for the treatment of alzheimer disease is provided, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing alzheimer disease.
In order to solve the problems of the technologies described above, the present invention by the following technical solutions:
A Chinese medicine for the treatment of alzheimer disease, is characterized in that, it is to be prepared into by the medical material of following parts by weight proportioning: 30 parts of Fructus Corni, 30 parts of Herba Epimedii, 20 parts of Placenta Hominiss, 20 parts of Radix Abelmoschi Sagittifolii, 12 parts of Rhizoma Curculiginises, 30 parts of Fructus Lycii, 9 parts of Fructus Schisandrae Chinensis, 12 parts of Rhizoma Acori Graminei, 12 parts of Radix Polygalaes, 12 parts of Bombyx Batryticatus(processed), 12 parts of Rhizoma Chuanxiongs, 12 parts of Semen Ziziphi Spinosaes, 12 parts of Caulis Polygoni Multiflori, 25 parts, Radix Rehmanniae Preparata, 25 parts of Rhizoma Polygonatis, 12 parts of Radix Polygoni Multiflori, 12 parts of Radix Angelicae Sinensis, 12 parts of Herba Cistanches, 20 parts of Radix Salviae Miltiorrhizaes, 25 parts of Radix Puerariaes, 25 parts of Semen Cuscutae, 15 parts of Fructus Rubies, 15 parts of Semen Astragali Complanatis, 20 parts of dried tubers, 20 parts of Cratoneuron filicinum (Hedw.) Spruc.(Lolsk), 15 parts of Herba Rosmarini Officinaliss, 12 parts of Semen Trigonellaes, 15 parts of Fructus Psoraleaes, 25 parts of Rhizoma Dioscoreaes, 25 parts of Radix Paeoniae Rubra, 30 parts of the Radixs Astragali, 30 parts of Radix Codonopsis, 15 parts of sulfur bacterias, 10 parts of Dens Draconiss, 20 parts, Rhizoma Gastrodiae, 20 parts of Pheretimas, 20 parts, Semen Persicae, 30 parts of Poria cum Radix Pinis, 15 parts of Herba Taxillis, 20 parts of Herba menyanthiss, 15 parts of Folium Mahoniae, 30 parts of Fructus Actinidiae Argutaes, 20 parts of Os Draconis, 20 parts of Concha Ostreae, 20 parts of Fructus Alpiniae Oxyphyllae, 15 parts of Ootheca Mantidiss, 12 parts of Rhizoma Coptidis.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, general material
Inventor in March, 2005-2014 are collected the out-patient of 30 routine alzheimer disease, age 66-80 year, course of disease 1-2 altogether between year February.Be divided at random: treatment group 20 examples, matched group 10 examples.The data there was no significant differences such as two groups of ages, the state of an illness, have comparability.
2, test method
Matched group oral placebo capsule, sooner or later respectively once.30 days courses for the treatment of.
The capsule that the oral the present invention for the treatment of group makes according to specific embodiment 1, every bu is taken for 2 times sooner or later.30 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
(1) recovery from illness: clinical symptoms and sign disappear completely or substantially disappear;
(2) effective: clinical symptoms and sign are most of to take a turn for the better or is clearly better;
(3) invalid; Clinical symptoms and sign are all not improved, and symptom is as front, DeGrain.
3.2 treatment statistical results are in table 1.
Table 1 liang group curative effect comparison
Group Case number Recovery from illness Effective Invalid Untoward reaction Total effective rate %
Treatment group 20 8 9 3 0(0%) 85%
Matched group 10 0 1 9 0(0%) 10%
Visible, the medicine that the preferred embodiment for the present invention makes can be treated alzheimer disease safely and effectively.
Detailed description of the invention
In order to understand better and to implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take 30 grams of Fructus Corni, 30 grams of Herba Epimedii, 20 grams of Placenta Hominiss, 20 grams of Radix Abelmoschi Sagittifolii, 12 grams of Rhizoma Curculiginises, 30 grams of Fructus Lycii, 9 grams of Fructus Schisandrae Chinensis, 12 grams of Rhizoma Acori Graminei, 12 grams of Radix Polygalaes, 12 grams of Bombyx Batryticatus(processed), 12 grams of Rhizoma Chuanxiongs, 12 grams of Semen Ziziphi Spinosaes, 12 grams of Caulis Polygoni Multiflori, 25 grams, Radix Rehmanniae Preparata, 25 grams of Rhizoma Polygonatis, 12 grams of Radix Polygoni Multiflori, 12 grams of Radix Angelicae Sinensis, 12 grams of Herba Cistanches, 20 grams of Radix Salviae Miltiorrhizaes, 25 grams of Radix Puerariaes, 25 grams of Semen Cuscutae, 15 grams of Fructus Rubies, 15 grams of Semen Astragali Complanatis, 20 grams of dried tubers, 20 grams of Cratoneuron filicinum (Hedw.) Spruc.(Lolsk), 15 grams of Herba Rosmarini Officinaliss, 12 grams of Semen Trigonellaes, 15 grams of Fructus Psoraleaes, 25 grams of Rhizoma Dioscoreaes, 25 grams of Radix Paeoniae Rubra, 30 grams of the Radixs Astragali, 30 grams of Radix Codonopsis, 15 grams of sulfur bacterias, 10 grams of Dens Draconiss, 20 grams, Rhizoma Gastrodiae, 20 grams of Pheretimas, 20 grams, Semen Persicae, 30 grams of Poria cum Radix Pinis, 15 grams of Herba Taxillis, 20 grams of Herba menyanthiss, 15 grams of Folium Mahoniae, 30 grams of Fructus Actinidiae Argutaes, 20 grams of Os Draconis, 20 grams of Concha Ostreae, 20 grams of Fructus Alpiniae Oxyphyllae, 15 grams of Ootheca Mantidiss, 12 grams of Rhizoma Coptidis.Add 10 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pack in capsulae vacuus, must meet the capsule of one day consumption of normal adult.
Be used for the treatment of alzheimer disease.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take 30 grams of Fructus Corni, 30 grams of Herba Epimedii, 20 grams of Placenta Hominiss, 20 grams of Radix Abelmoschi Sagittifolii, 12 grams of Rhizoma Curculiginises, 30 grams of Fructus Lycii, 9 grams of Fructus Schisandrae Chinensis, 12 grams of Rhizoma Acori Graminei, 12 grams of Radix Polygalaes, 12 grams of Bombyx Batryticatus(processed), 12 grams of Rhizoma Chuanxiongs, 12 grams of Semen Ziziphi Spinosaes, 12 grams of Caulis Polygoni Multiflori, 25 grams, Radix Rehmanniae Preparata, 25 grams of Rhizoma Polygonatis, 12 grams of Radix Polygoni Multiflori, 12 grams of Radix Angelicae Sinensis, 12 grams of Herba Cistanches, 20 grams of Radix Salviae Miltiorrhizaes, 25 grams of Radix Puerariaes, 25 grams of Semen Cuscutae, 15 grams of Fructus Rubies, 15 grams of Semen Astragali Complanatis, 20 grams of dried tubers, 20 grams of Cratoneuron filicinum (Hedw.) Spruc.(Lolsk), 15 grams of Herba Rosmarini Officinaliss, 12 grams of Semen Trigonellaes, 15 grams of Fructus Psoraleaes, 25 grams of Rhizoma Dioscoreaes, 25 grams of Radix Paeoniae Rubra, 30 grams of the Radixs Astragali, 30 grams of Radix Codonopsis, 15 grams of sulfur bacterias, 10 grams of Dens Draconiss, 20 grams, Rhizoma Gastrodiae, 20 grams of Pheretimas, 20 grams, Semen Persicae, 30 grams of Poria cum Radix Pinis, 15 grams of Herba Taxillis, 20 grams of Herba menyanthiss, 15 grams of Folium Mahoniae, 30 grams of Fructus Actinidiae Argutaes, 20 grams of Os Draconis, 20 grams of Concha Ostreae, 20 grams of Fructus Alpiniae Oxyphyllae, 15 grams of Ootheca Mantidiss, 12 grams of Rhizoma Coptidis.Add 12 times of water gagings, decoct 2 hours, filter; Filtering residue adds 10 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, pack, must meet the powder of one day consumption of normal adult.
Be used for the treatment of alzheimer disease.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take 30 grams of Fructus Corni, 30 grams of Herba Epimedii, 20 grams of Placenta Hominiss, 20 grams of Radix Abelmoschi Sagittifolii, 12 grams of Rhizoma Curculiginises, 30 grams of Fructus Lycii, 9 grams of Fructus Schisandrae Chinensis, 12 grams of Rhizoma Acori Graminei, 12 grams of Radix Polygalaes, 12 grams of Bombyx Batryticatus(processed), 12 grams of Rhizoma Chuanxiongs, 12 grams of Semen Ziziphi Spinosaes, 12 grams of Caulis Polygoni Multiflori, 25 grams, Radix Rehmanniae Preparata, 25 grams of Rhizoma Polygonatis, 12 grams of Radix Polygoni Multiflori, 12 grams of Radix Angelicae Sinensis, 12 grams of Herba Cistanches, 20 grams of Radix Salviae Miltiorrhizaes, 25 grams of Radix Puerariaes, 25 grams of Semen Cuscutae, 15 grams of Fructus Rubies, 15 grams of Semen Astragali Complanatis, 20 grams of dried tubers, 20 grams of Cratoneuron filicinum (Hedw.) Spruc.(Lolsk), 15 grams of Herba Rosmarini Officinaliss, 12 grams of Semen Trigonellaes, 15 grams of Fructus Psoraleaes, 25 grams of Rhizoma Dioscoreaes, 25 grams of Radix Paeoniae Rubra, 30 grams of the Radixs Astragali, 30 grams of Radix Codonopsis, 15 grams of sulfur bacterias, 10 grams of Dens Draconiss, 20 grams, Rhizoma Gastrodiae, 20 grams of Pheretimas, 20 grams, Semen Persicae, 30 grams of Poria cum Radix Pinis, 15 grams of Herba Taxillis, 20 grams of Herba menyanthiss, 15 grams of Folium Mahoniae, 30 grams of Fructus Actinidiae Argutaes, 20 grams of Os Draconis, 20 grams of Concha Ostreae, 20 grams of Fructus Alpiniae Oxyphyllae, 15 grams of Ootheca Mantidiss, 12 grams of Rhizoma Coptidis.Add 8 times of water gagings, decoct 2 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, and granulate according to this area common process, pack, must meet the granule of one day consumption of normal adult.
Be used for the treatment of alzheimer disease.Oral, every bu is taken for twice sooner or later.
Facts have proved through a large amount of clinical treatments, the present invention treats the Chinese medicine of alzheimer disease, belongs to pure Chinese medicinal preparation, little to human body toxicity, side effect, to treatment alzheimer disease have reliably, safety, significant therapeutic effect.

Claims (1)

1. a Chinese medicine for the treatment of alzheimer disease, is characterized in that, it is to be prepared into by the medical material of following parts by weight proportioning: 30 parts of Fructus Corni, 30 parts of Herba Epimedii, 20 parts of Placenta Hominiss, 20 parts of Radix Abelmoschi Sagittifolii, 12 parts of Rhizoma Curculiginises, 30 parts of Fructus Lycii, 9 parts of Fructus Schisandrae Chinensis, 12 parts of Rhizoma Acori Graminei, 12 parts of Radix Polygalaes, 12 parts of Bombyx Batryticatus(processed), 12 parts of Rhizoma Chuanxiongs, 12 parts of Semen Ziziphi Spinosaes, 12 parts of Caulis Polygoni Multiflori, 25 parts, Radix Rehmanniae Preparata, 25 parts of Rhizoma Polygonatis, 12 parts of Radix Polygoni Multiflori, 12 parts of Radix Angelicae Sinensis, 12 parts of Herba Cistanches, 20 parts of Radix Salviae Miltiorrhizaes, 25 parts of Radix Puerariaes, 25 parts of Semen Cuscutae, 15 parts of Fructus Rubies, 15 parts of Semen Astragali Complanatis, 20 parts of dried tubers, 20 parts of Cratoneuron filicinum (Hedw.) Spruc.(Lolsk), 15 parts of Herba Rosmarini Officinaliss, 12 parts of Semen Trigonellaes, 15 parts of Fructus Psoraleaes, 25 parts of Rhizoma Dioscoreaes, 25 parts of Radix Paeoniae Rubra, 30 parts of the Radixs Astragali, 30 parts of Radix Codonopsis, 15 parts of sulfur bacterias, 10 parts of Dens Draconiss, 20 parts, Rhizoma Gastrodiae, 20 parts of Pheretimas, 20 parts, Semen Persicae, 30 parts of Poria cum Radix Pinis, 15 parts of Herba Taxillis, 20 parts of Herba menyanthiss, 15 parts of Folium Mahoniae, 30 parts of Fructus Actinidiae Argutaes, 20 parts of Os Draconis, 20 parts of Concha Ostreae, 20 parts of Fructus Alpiniae Oxyphyllae, 15 parts of Ootheca Mantidiss, 12 parts of Rhizoma Coptidis.
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104548020A (en) * 2014-12-31 2015-04-29 东莞市智健医疗科技有限公司 Application of medicine composition in preparing medicine curing senile dementia
KR101946818B1 (en) 2015-03-12 2019-02-13 주식회사 파미니티 Composition for Improving Memory, Preventing, Improving or Treating Cognitive Disorder and Brain Diseases

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CN1181966A (en) * 1997-09-19 1998-05-20 薛廷民 Medicine for senile dementia and its preparation
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104548020A (en) * 2014-12-31 2015-04-29 东莞市智健医疗科技有限公司 Application of medicine composition in preparing medicine curing senile dementia
CN104548020B (en) * 2014-12-31 2017-11-07 东莞市智健医疗科技有限公司 A kind of purposes of pharmaceutical composition in treatment senile dementia is prepared
KR101946818B1 (en) 2015-03-12 2019-02-13 주식회사 파미니티 Composition for Improving Memory, Preventing, Improving or Treating Cognitive Disorder and Brain Diseases

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