CN104173878A - Traditional Chinese medicine for treating acute glomerulonephritis - Google Patents

Traditional Chinese medicine for treating acute glomerulonephritis Download PDF

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CN104173878A
CN104173878A CN201410443272.9A CN201410443272A CN104173878A CN 104173878 A CN104173878 A CN 104173878A CN 201410443272 A CN201410443272 A CN 201410443272A CN 104173878 A CN104173878 A CN 104173878A
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parts
grams
herba
radix
rhizoma
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张震
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Abstract

The invention discloses a traditional Chinese medicine for treating acute glomerulonephritis. The traditional Chinese medicine is prepared from the following medicinal materials in parts by weight: mussaenda pubescens, celandine, white willow, ardisia crispa, false loosestrife, poria cocos, grifola, veronicastrum herb, bighead atractylodes rhizome, ficus formosana, lantern plant calyx, ramose scouring rush herb, lalang grass rhizome, costus tonkinensis, corn stigma, hairy euphorbia, phaseolus calcaratus, ground hemlock, phyllanthus ruinaria, plantain herb, rhizoma smilacis glabrae, rubia cordifolia, semen pharbitidis, pilea pumila, cortex kadsurae radicis, honeysuckle, fructus forsythia, exocarpium benincasae, duckweed, periostracum cicada, lumbricus, cortex dictamni, rhizoma dioscoreae nipponicae, ginkgo, tender catchweed bedstraw herb, carbo of typhae pollen, semen plantaginis (package), dandelion, selfheal, scutellaria baicalensis, radix codonopsis, salviae miltiorrhizae, red peony root, cortex mori radicis, fructus lycii, oldenlandia diffusa, cordate houttuynia, achyranthes bidentata, rhizoma alismatis and platycodon grandiflorum. A clinical experiment proves that the acute glomerulonephritis can be safely and effectively treated by the traditional Chinese medicine.

Description

A kind of Chinese medicine for the treatment of acute glomerulonephritis
Technical field
The present invention relates to a kind of field of Chinese medicines, particularly a kind of Chinese medicine for the treatment of acute glomerulonephritis.
Background technology
Acute nephritis is that a kind of both sides kidney diffusivity glomerule infringement causing due to allergy after infecting is main acute illness, the feature of primary disease is that onset is more anxious, there is the serial clinical manifestations such as hematuria, albuminuria, cylinderuria, edema, oliguria, hypertension in 1-3 week after infection, acute glomerulonephritis clinical manifestation symptom most patient in 1. early stage has pioneer to infect history in previous month in morbidity, as suppurative tonsillitis, onset is unexpected, hyperpyrexia, but also can recessive slowly onset.2. onset starts mainly with oliguria, or oliguria, even anuria gradually.Can be simultaneously with gross hematuria, the persistent period not etc., but microscopic hematuria sustainable existence, routine urinalysis changes with acute glomerulonephritis basic identical.3. there is edema in the about half patient of edema in the time starting oliguria, attaches most importance to face and lower limb.Once edema occurs being difficult to disappear.4. part patient, with hypertension, also has and after onset, in process, occurs hypertension when hypertension onset, once blood pressure increases, is persistence, is difficult for automatic descending.5. to be that persistence increases the weight of be the feature of primary disease to renal function injury.Glomerular filtration rate obviously reduces and renal tubular function obstacle exists simultaneously.Still lack at present the effective medicine of generally recognized as safe for acute glomerulonephritis.At present treatment acute glomerulonephritis medicine is cured the symptoms, not the disease, and conventionally has dependency and a side effect.Therefore the Chinese medicine of researching and developing a kind of safe and effective treatment acute glomerulonephritis is very with practical value.
Summary of the invention
The problem to be solved in the present invention is: a kind of Chinese medicine for the treatment of acute glomerulonephritis is provided, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing acute glomerulonephritis.
In order to solve the problems of the technologies described above, the present invention by the following technical solutions:
A Chinese medicine for the treatment of acute glomerulonephritis, is characterized in that, it is to be prepared into by the medical material of following parts by weight proportioning: 12 parts of Radix Mussaendae, 12 parts of Herba Chelidoniis, 15 parts of Salix albas, 12 parts of Radix Ardisiae Crispaes, 12 parts of Herba Ludwigiae Prostratae, 12 parts, Poria, 12 parts of Polyporus, 12 parts of Herba veronicastri villosulis, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Taiwan banyans, 12 parts of Calyx seu Fructus physaliss, 12 parts of Herba equiseti ramosissimis, 15 parts of Rhizoma Imperataes, 12 parts of light leaf Costus speciosuss, 15 parts of Stigma Maydis, 12 parts of Ramulus et Folium Bauhiniae Faberi, 25 parts of Semen Phaseolis, 15 parts of Ramulus et folium taxi cuspidataes, 10 parts of Cacumen Securinegae Suffruticosaes, 20 parts of Herba Plantaginiss, 20 parts of Rhizoma Smilacis Glabraes, 12 parts, Radix Rubiae, 3 parts of Semen Pharbitidiss, 10 parts of pilea mongolicas, 12 parts of Cortex cercis chinensiss, 15 parts of Flos Loniceraes, 15 parts of Fructus Forsythiaes, 15 parts of Exocarpium Benincasaes, 12 parts, Herba Spirodelae, 9 parts of Periostracum Cicadaes, 12 parts of Pheretimas, 12 parts of Cortex Dictamni, 12 parts of Rhizoma Dioscoreae Nipponicae, 9 parts of Semen Ginkgoes, 12 parts of Herba Galii Teneris, 9 parts of Pollen Typhae carbon, 12 parts of Semen Plantaginiss (bag), 15 parts of Herba Taraxacis, 15 parts of Spica Prunellaes, 12 parts of Radix Scutellariaes, 15 parts of Radix Codonopsis, 12 parts of Radix Salviae Miltiorrhizaes, 12 parts of Radix Paeoniae Rubra, 12 parts of Cortex Mori, 15 parts of Fructus Lycii, 30 parts of Herba Hedyotidis Diffusaes, 20 parts of Herba Houttuyniae, 10 parts of Radix Achyranthis Bidentataes, 9 parts of Rhizoma Alismatis, 9 parts of Radix Platycodoniss.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, general material
Inventor in February, 2009-2013 are collected the out-patient of 50 routine acute glomerulonephritiss, age 21-55 year, course of disease 2-3 altogether between year March.Be divided at random: treatment group 30 examples, matched group 20 examples.The data there was no significant differences such as two groups of ages, the state of an illness, have comparability.
2, test method
Matched group oral placebo capsule, sooner or later respectively once.30 days courses for the treatment of.
The capsule that the oral the present invention for the treatment of group makes according to specific embodiment 1, every bu is taken for 2 times sooner or later.30 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
(1) recovery from illness: clinical symptoms and sign disappear completely or substantially disappear;
(2) effective: clinical symptoms and sign are most of to take a turn for the better or is clearly better;
(3) invalid; Clinical symptoms and sign are all not improved, and symptom is as front, DeGrain.
3.2 treatment statistical results are in table 1.
Table 1 liang group curative effect comparison
Group Case number Recovery from illness Effective Invalid Untoward reaction Total effective rate %
Treatment group 30 20 7 3 0(0%) 90%
Matched group 20 0 1 19 0(0%) 5%
Visible, the medicine that the preferred embodiment for the present invention makes can be treated acute glomerulonephritis safely and effectively.
Detailed description of the invention
In order to understand better and to implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take 12 grams of Radix Mussaendae, 12 grams of Herba Chelidoniis, 15 grams of Salix albas, 12 grams of Radix Ardisiae Crispaes, 12 grams of Herba Ludwigiae Prostratae, 12 grams, Poria, 12 grams of Polyporus, 12 grams of Herba veronicastri villosulis, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 10 grams of Taiwan banyans, 12 grams of Calyx seu Fructus physaliss, 12 grams of Herba equiseti ramosissimis, 15 grams of Rhizoma Imperataes, 12 grams of light leaf Costus speciosuss, 15 grams of Stigma Maydis, 12 grams of Ramulus et Folium Bauhiniae Faberi, 25 grams of Semen Phaseolis, 15 grams of Ramulus et folium taxi cuspidataes, 10 grams of Cacumen Securinegae Suffruticosaes, 20 grams of Herba Plantaginiss, 20 grams of Rhizoma Smilacis Glabraes, 12 grams, Radix Rubiae, 3 grams of Semen Pharbitidiss, 10 grams of pilea mongolicas, 12 grams of Cortex cercis chinensiss, 15 grams of Flos Loniceraes, 15 grams of Fructus Forsythiaes, 15 grams of Exocarpium Benincasaes, 12 grams, Herba Spirodelae, 9 grams of Periostracum Cicadaes, 12 grams of Pheretimas, 12 grams of Cortex Dictamni, 12 grams of Rhizoma Dioscoreae Nipponicae, 9 grams of Semen Ginkgoes, 12 grams of Herba Galii Teneris, 9 grams of Pollen Typhae carbon, 12 grams of Semen Plantaginiss (bag), 15 grams of Herba Taraxacis, 15 grams of Spica Prunellaes, 12 grams of Radix Scutellariaes, 15 grams of Radix Codonopsis, 12 grams of Radix Salviae Miltiorrhizaes, 12 grams of Radix Paeoniae Rubra, 12 grams of Cortex Mori, 15 grams of Fructus Lycii, 30 grams of Herba Hedyotidis Diffusaes, 20 grams of Herba Houttuyniae, 10 grams of Radix Achyranthis Bidentataes, 9 grams of Rhizoma Alismatis, 9 grams of Radix Platycodoniss.Add 10 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pack in capsulae vacuus, must meet the capsule of one day consumption of normal adult.
Be used for the treatment of acute glomerulonephritis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take 12 grams of Radix Mussaendae, 12 grams of Herba Chelidoniis, 15 grams of Salix albas, 12 grams of Radix Ardisiae Crispaes, 12 grams of Herba Ludwigiae Prostratae, 12 grams, Poria, 12 grams of Polyporus, 12 grams of Herba veronicastri villosulis, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 10 grams of Taiwan banyans, 12 grams of Calyx seu Fructus physaliss, 12 grams of Herba equiseti ramosissimis, 15 grams of Rhizoma Imperataes, 12 grams of light leaf Costus speciosuss, 15 grams of Stigma Maydis, 12 grams of Ramulus et Folium Bauhiniae Faberi, 25 grams of Semen Phaseolis, 15 grams of Ramulus et folium taxi cuspidataes, 10 grams of Cacumen Securinegae Suffruticosaes, 20 grams of Herba Plantaginiss, 20 grams of Rhizoma Smilacis Glabraes, 12 grams, Radix Rubiae, 3 grams of Semen Pharbitidiss, 10 grams of pilea mongolicas, 12 grams of Cortex cercis chinensiss, 15 grams of Flos Loniceraes, 15 grams of Fructus Forsythiaes, 15 grams of Exocarpium Benincasaes, 12 grams, Herba Spirodelae, 9 grams of Periostracum Cicadaes, 12 grams of Pheretimas, 12 grams of Cortex Dictamni, 12 grams of Rhizoma Dioscoreae Nipponicae, 9 grams of Semen Ginkgoes, 12 grams of Herba Galii Teneris, 9 grams of Pollen Typhae carbon, 12 grams of Semen Plantaginiss (bag), 15 grams of Herba Taraxacis, 15 grams of Spica Prunellaes, 12 grams of Radix Scutellariaes, 15 grams of Radix Codonopsis, 12 grams of Radix Salviae Miltiorrhizaes, 12 grams of Radix Paeoniae Rubra, 12 grams of Cortex Mori, 15 grams of Fructus Lycii, 30 grams of Herba Hedyotidis Diffusaes, 20 grams of Herba Houttuyniae, 10 grams of Radix Achyranthis Bidentataes, 9 grams of Rhizoma Alismatis, 9 grams of Radix Platycodoniss.Add 12 times of water gagings, decoct 2 hours, filter; Filtering residue adds 10 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, pack, must meet the powder of one day consumption of normal adult.
Be used for the treatment of acute glomerulonephritis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take 12 grams of Radix Mussaendae, 12 grams of Herba Chelidoniis, 15 grams of Salix albas, 12 grams of Radix Ardisiae Crispaes, 12 grams of Herba Ludwigiae Prostratae, 12 grams, Poria, 12 grams of Polyporus, 12 grams of Herba veronicastri villosulis, 10 grams of the Rhizoma Atractylodis Macrocephalaes, 10 grams of Taiwan banyans, 12 grams of Calyx seu Fructus physaliss, 12 grams of Herba equiseti ramosissimis, 15 grams of Rhizoma Imperataes, 12 grams of light leaf Costus speciosuss, 15 grams of Stigma Maydis, 12 grams of Ramulus et Folium Bauhiniae Faberi, 25 grams of Semen Phaseolis, 15 grams of Ramulus et folium taxi cuspidataes, 10 grams of Cacumen Securinegae Suffruticosaes, 20 grams of Herba Plantaginiss, 20 grams of Rhizoma Smilacis Glabraes, 12 grams, Radix Rubiae, 3 grams of Semen Pharbitidiss, 10 grams of pilea mongolicas, 12 grams of Cortex cercis chinensiss, 15 grams of Flos Loniceraes, 15 grams of Fructus Forsythiaes, 15 grams of Exocarpium Benincasaes, 12 grams, Herba Spirodelae, 9 grams of Periostracum Cicadaes, 12 grams of Pheretimas, 12 grams of Cortex Dictamni, 12 grams of Rhizoma Dioscoreae Nipponicae, 9 grams of Semen Ginkgoes, 12 grams of Herba Galii Teneris, 9 grams of Pollen Typhae carbon, 12 grams of Semen Plantaginiss (bag), 15 grams of Herba Taraxacis, 15 grams of Spica Prunellaes, 12 grams of Radix Scutellariaes, 15 grams of Radix Codonopsis, 12 grams of Radix Salviae Miltiorrhizaes, 12 grams of Radix Paeoniae Rubra, 12 grams of Cortex Mori, 15 grams of Fructus Lycii, 30 grams of Herba Hedyotidis Diffusaes, 20 grams of Herba Houttuyniae, 10 grams of Radix Achyranthis Bidentataes, 9 grams of Rhizoma Alismatis, 9 grams of Radix Platycodoniss.Add 8 times of water gagings, decoct 2 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, and granulate according to this area common process, pack, must meet the granule of one day consumption of normal adult.
Be used for the treatment of acute glomerulonephritis.Oral, every bu is taken for twice sooner or later.
Facts have proved through a large amount of clinical treatments, the present invention treats the Chinese medicine of acute glomerulonephritis, belongs to pure Chinese medicinal preparation, little to human body toxicity, side effect, to treatment acute glomerulonephritis have reliably, safety, significant therapeutic effect.

Claims (1)

1. a Chinese medicine for the treatment of acute glomerulonephritis, is characterized in that, it is to be prepared into by the medical material of following parts by weight proportioning: 12 parts of Radix Mussaendae, 12 parts of Herba Chelidoniis, 15 parts of Salix albas, 12 parts of Radix Ardisiae Crispaes, 12 parts of Herba Ludwigiae Prostratae, 12 parts, Poria, 12 parts of Polyporus, 12 parts of Herba veronicastri villosulis, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Taiwan banyans, 12 parts of Calyx seu Fructus physaliss, 12 parts of Herba equiseti ramosissimis, 15 parts of Rhizoma Imperataes, 12 parts of light leaf Costus speciosuss, 15 parts of Stigma Maydis, 12 parts of Ramulus et Folium Bauhiniae Faberi, 25 parts of Semen Phaseolis, 15 parts of Ramulus et folium taxi cuspidataes, 10 parts of Cacumen Securinegae Suffruticosaes, 20 parts of Herba Plantaginiss, 20 parts of Rhizoma Smilacis Glabraes, 12 parts, Radix Rubiae, 3 parts of Semen Pharbitidiss, 10 parts of pilea mongolicas, 12 parts of Cortex cercis chinensiss, 15 parts of Flos Loniceraes, 15 parts of Fructus Forsythiaes, 15 parts of Exocarpium Benincasaes, 12 parts, Herba Spirodelae, 9 parts of Periostracum Cicadaes, 12 parts of Pheretimas, 12 parts of Cortex Dictamni, 12 parts of Rhizoma Dioscoreae Nipponicae, 9 parts of Semen Ginkgoes, 12 parts of Herba Galii Teneris, 9 parts of Pollen Typhae carbon, 12 parts of Semen Plantaginiss (bag), 15 parts of Herba Taraxacis, 15 parts of Spica Prunellaes, 12 parts of Radix Scutellariaes, 15 parts of Radix Codonopsis, 12 parts of Radix Salviae Miltiorrhizaes, 12 parts of Radix Paeoniae Rubra, 12 parts of Cortex Mori, 15 parts of Fructus Lycii, 30 parts of Herba Hedyotidis Diffusaes, 20 parts of Herba Houttuyniae, 10 parts of Radix Achyranthis Bidentataes, 9 parts of Rhizoma Alismatis, 9 parts of Radix Platycodoniss.
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105012767A (en) * 2015-08-20 2015-11-04 黄峰 Orally-taken medicament for treating acute postinfectious glomerulonephritis and preparation method thereof
CN106421561A (en) * 2016-11-28 2017-02-22 广西慧投互联网金融服务有限公司 Heat-clearing and diuretic traditional Chinese medicine composition

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1268355A (en) * 2000-01-08 2000-10-04 陈柏林 Yichanmanshenkang medicine for curing nephroses

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1268355A (en) * 2000-01-08 2000-10-04 陈柏林 Yichanmanshenkang medicine for curing nephroses

Non-Patent Citations (3)

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Title
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朱定华: "《基层医生临床实用全书》", 31 January 2006 *
李瑞岭等: "《内科金方》", 31 July 2001 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105012767A (en) * 2015-08-20 2015-11-04 黄峰 Orally-taken medicament for treating acute postinfectious glomerulonephritis and preparation method thereof
CN106421561A (en) * 2016-11-28 2017-02-22 广西慧投互联网金融服务有限公司 Heat-clearing and diuretic traditional Chinese medicine composition

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