CN104187168B - A kind of compound premix preventing quail cold stress enteritis - Google Patents
A kind of compound premix preventing quail cold stress enteritis Download PDFInfo
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- CN104187168B CN104187168B CN201410459881.3A CN201410459881A CN104187168B CN 104187168 B CN104187168 B CN 104187168B CN 201410459881 A CN201410459881 A CN 201410459881A CN 104187168 B CN104187168 B CN 104187168B
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Abstract
The present invention relates to a kind of compound premix special preventing quail cold stress enteritis, belong to feed additive field, solve current the Northeast quail cold stress enteritis and take place frequently and serious common problem.The premix that concentrated medicine, vitamin, mineral matter, functional component are integrated is provided.Chinese medicine in premix Chinese prescription of the present invention, by the principle compatibility of " monarch ", finally innovatively determines kind and the optimum amount of Chinese herbal medicine through repetition test and checking.Play the anti-cold stress of glucosidase procyanidins simultaneously, improve these two kinds of functions of meat, omit the interpolation using vitamin C and vitamin E.
Description
Technical field
The invention provides a kind of compound premix preventing quail cold stress enteritis, belong to field of feed additive technology.
Background technology
Quail is the special fowl that economic worth is very high, and China has become the first in the world and supported quail big country, have the good reputation of " animal ginseng ".Be considered as high-grade nourishing treasure by people, be also the important source material of herbal cuisine simultaneously.Quail not only edible nourishing is worth very high, its medical value is also very high, domestic quail aquaculture mainly concentrates on east and central China area, the Northeast is because of region cold and low temperature time remaining is long, environment temperature is starkly lower than the minimum temperature needed for Feeding Quails, quail due to health little, alimentary canal is not long, digestion power is not as good as other birds, responsive, strong to cold stress (Coldstress) reaction, the disease of digestive tracts such as quail poor growth, meat decline, diarrhoea malaria is had blood in stool are high, the death rate is high, and quail is higher to nutrient requirement.At present, almost do not have for quail premix compound special, all make the conventional premix of birds in quail perfect compound feed, effect is not obvious, specific aim is poor, premix for anti-cold stress has no in prior art to be recorded, the quail premix compound special be not integrated about concentrated medicine, vitamin, mineral matter, functional component.
About glucosidase procyanidins, according to the difference of the degree of polymerization, OPC is divided into again glucosidase procyanidins (oligomericproathocyanidin, OPC) and height to gather OPC (polymericproathocyanidin, PPC).The OPC of the degree of polymerization more than 7 is called high poly-OPC, and the degree of polymerization is that the OPC of 2-7 is called glucosidase procyanidins.Free radical superfluous in OPC energy purged body, improve the immunity of human body, can be used as anti-cancer, anti-sudden change, the principle active component of prevention and cure of cardiovascular disease medicine and the natural etc. as safety non-toxic, have been widely used at field tools such as medicine, health care, food, daily-use chemical industries.Glucosidase procyanidins has stronger physiologically active.Glucosidase procyanidins has very strong oxidation resistance.The antioxidation activity of OPC is higher than VE and VC in vivo, and glucosidase procyanidins also has antibacterial, anti-inflammatory; Glucosidase procyanidins also can maintain skin elasticity, improves cutis laxa, coarse, wrinkle and regulation of skin function.In prior art, glucosidase procyanidins is used for feed addictive and also has report, CN103271235A discloses the application of glucosidase procyanidins as the feed addictive of prolongation quality guaranteed period of eggs, is wherein also applied to quail.CN1654463A discloses a kind of oligomeric proanthocyanidins and preparation method and application, and the oligomeric proanthocyanidins wherein adding 400mg/kg in poultry feed does not affect egg quality, can also reduce the content of cholesterol in egg.Also do not report at present and use it for the anti-cold stress of quail.
Summary of the invention
Object of the present invention: provide a kind of and there is the premix that cost is low, technique simple, be easy to operation, be integrated without the need to complex device, the concentrated medicine being applicable to the advantages such as large-scale breeding, vitamin, mineral matter, functional component.
The technical problem that the present invention solves: solve current the Northeast quail cold stress enteritis and take place frequently and serious common problem.The premix that concentrated medicine, vitamin, mineral matter, functional component are integrated is provided.
Technical scheme of the present invention:
On the basis of inventor's previous work, inventor provide a kind of compound premix preventing quail cold stress enteritis, with parts by weight: glucosidase procyanidins 10-20 part, dandelion 5-8 part, bark of eucommia 5-8 part, purslane 5-8 part, cordate houttuynia 5-8 part, Radix Astragali 5-8 part, plantain seed 5-8 part, mother chrysanthemum 5-8 part, vitamin A 0.5-0.8 part, vitamin D
30.01-0.3 part, Cobastab
10.05-0.07 part, Cobastab
20.5-1 part, Cobastab
60.1-0.6 part, Cobastab
120.08-0.1 part, folic acid 0.06-0.18 part, biotin 0.02-0.25 part, nicotinic acid 0.8-1.2 part; Kelp Powder 5-8 part, sodium selenite 2-3 part.
Described premix is pulverized rear mixing by each raw material drying and be get final product.
The application of described premix: Meat-type quail, under the condition of 0 ~ 12 ± 1 DEG C, adds this premix by weight 0.003%-0.01% in Meat-type quail adequate diet.
The present invention also provides a kind of preparation method preventing the compound premix of quail cold stress enteritis, dandelion 5-8 part, bark of eucommia 5-8 part, purslane 5-8 part, cordate houttuynia 5-8 part, Radix Astragali 5-8 part, plantain seed 5-8 part, mother chrysanthemum 5-8 part are mixed and made into the trickle powder of 600 object by this preparation method, both.Also by the warm water of fine powder with 60 DEG C, by weight, can soak 2 hours with the material-water ratio of 1:2, then heat 30-50 minute with slow fire, concentration is 1/2nd of original volume, obtains filtrate, mix and get final product after dusting with other raw material of described weight portion after filtration.
Premix of the present invention can also use other conventional method to prepare.
Dandelion, has another name called dandelion, is the kind that health ministry lists medicine-food two-purpose recently in.Record according to Compendium of Material Medica, dandelion can heat-clearing poison, helping digestion is malicious, disappear that it is swollen to dislike.
The bark of eucommia: filling liver kidney, strengthening the bones and muscles.
Cordate houttuynia: taste is pungent; Cold nature; Return lung channel.Effect is clearing heat and detoxicating, inducing diuresis to reduce edema.Control pneumonia, lung abscess, hot dysentery, malaria, oedema, gonorrhoea, leukorrhea.
Chrysanthemum have mother chrysanthemum and family chrysanthemum point, wherein family chrysanthemum clears liver and improve vision, and the loose fire of mother chrysanthemum toxic removing, sweetness and bitterness is slightly cold, clearing heat and detoxicating, all has certain effectiveness to eye strain, headache, hypertension etc.In Compendium of Material Medica, the drug effect of chrysanthemum tea is also documented in detail: property is sweet, be slightly cold, there is effect of loose wind-heat, flat liver improving eyesight.
Radix Astragali invigorating qi for consolidating superficies, holder sore myogenic.
Plantain seed reducing fever and causing diuresis.
Purslane has clearing heat and detoxicating, the effect such as to stop blooding treating stranguria.Cure mainly acute, subacute dermatitis and enteritis, bacillary dysentery, treatment pyogenic infections from tumour or sore, damage by worms bite, eczema, appendicitis, hookworm disease, banded spore rash and functional uterine bleeding.1. antibacterial action: ethanol extract has the inhibitory action of height to Escherichia coli, proteus, shigella dysenteriae, typhoid fever, paratyphosum Bacterium. also there is inhibitory action in various degree to staphylococcus aureus, fungi such as Austria Du big belly microspore tinea bacterium, tubercle bacillus.Slight inhibitory action is had to Pseudomonas aeruginosa. experiment shows, when mouse peritoneal Escherichia Coli Injection infects, then invalid with residue water decoction after alcohol extract or alcohol extracting.
Beneficial effect of the present invention:
(1) premix that medicine, vitamin, mineral matter, functional component are integrated is concentrated in this premix.
(2) Chinese medicine in premix Chinese prescription of the present invention is by the principle compatibility of " monarch ", kind and the optimum amount of Chinese herbal medicine is finally innovatively determined through repetition test and checking, under the existence of vitamin and mineral matter, greatly reduce the use of Chinese medicine material kind, although reduce, but still have synergistic function between various traditional Chinese medicine ingredients, its technique effect is also very good, to treatment quail cold stress enteritis, there is splendid and unexpected technique effect.The present invention with the clearing heat and detoxicating dandelion of the cool blood of detoxicating, clearing heat and detoxicating antibacterial purslane for monarch, minister is clearing heat and detoxicating to have, the hot dysentery of inducing diuresis to reduce edema, the cordate houttuynia of malaria effect, help with invigorating qi for consolidating superficies, the Radix Astragali of holder sore myogenic and the plantain seed of reducing fever and causing diuresis, to have the loose fire of toxic removing, the chrysanthemum that sweetness and bitterness is slightly cold is for making coordinating the drug actions of a prescription.
(3) playing the anti-cold stress of glucosidase procyanidins simultaneously, improve these two kinds of functions of meat, is trial and the breakthrough of field of fodder; Inventor finds unexpectedly, uses glucosidase procyanidins can omit the interpolation using vitamin C and vitamin E, still can obtain same technique effect, reduce cost.
(4) mineral matter only uses the effect that Kelp Powder, sodium selenite just can reach.Each constituent content cooperatively interacts, Synergistic, the obvious grow of anti-cold stress ability of Meat-type quail, and intestines problem significantly reduces, and meat tenderizes and flexible.This feed addictive can meet the nutritional need that poultry is in best immune state, improves poultry, especially the ability of supporting cold stress of quail.The present invention can avoid the use of the additive such as hormone, antibiotic, is of value to the health of animals and humans, increases edible safety.
Detailed description of the invention
Embodiment 1: a kind of compound premix special preventing quail cold stress enteritis, it is characterized in that this compound premix is made up of following raw material, with parts by weight: glucosidase procyanidins 10 parts, dandelion 5 parts, the bark of eucommia 5 parts, purslane 5 parts, cordate houttuynia 5 parts, the Radix Astragali 5 parts, plantain seed 5 parts, mother chrysanthemum 5 parts, vitamin A 0.5 part, vitamin D
30.01 part, Cobastab
10.05 part, Cobastab
20.5, Cobastab
60.1 part, Cobastab
120.08 part, 0.06 part, folic acid, biotin 0.02 part, 0.8 part, nicotinic acid; Kelp Powder 5 parts, sodium selenite 2 parts.
Embodiment 2: a kind of compound premix special preventing quail cold stress enteritis, it is characterized in that this compound premix is made up of following raw material, with parts by weight: glucosidase procyanidins 20 parts, dandelion 8 parts, the bark of eucommia 8 parts, purslane 8 parts, cordate houttuynia 8 parts, the Radix Astragali 8 parts, plantain seed 8 parts, mother chrysanthemum 8 parts, vitamin A 0.8 part, vitamin D
30.3 part, Cobastab
10.07 part, Cobastab
21 part, Cobastab
60.6 part, Cobastab
120.1 part, 0.18 part, folic acid, biotin 0.25 part, 1.2 parts, nicotinic acid; Kelp Powder 8 parts, sodium selenite 3 parts.
Embodiment 3 one kinds prevents the compound premix special of quail cold stress enteritis, it is characterized in that this compound premix is made up of following raw material, with parts by weight: glucosidase procyanidins 15 parts, dandelion 7 parts, the bark of eucommia 6 parts, purslane 6 parts, cordate houttuynia 6 parts, the Radix Astragali 6 parts, plantain seed 6 parts, mother chrysanthemum 6 parts, vitamin A 0.6 part, vitamin D
30.08 part, Cobastab
10.06 part, Cobastab
20.6 part, Cobastab
60.5 part, Cobastab
120.09 part, 0.08 part, folic acid, biotin 0.08 part, 1.0 parts, nicotinic acid; Kelp Powder 6 parts, sodium selenite 2.5 parts.
Contrast test
Materials and methods
Laboratory sample: Chinese medicine composition of the present invention and feed, by formula of the present invention and method preparation.
Animal used as test
Experimental animal is the Sha Weimate Meat-type quail of 1 age in days, totally 220, when raising to 7 age in days, be divided into 2 groups at random, often organize 120, 1 group is that Normal group (feed routinely by quail perfect compound feed, containing conventional quail or fowl vitamin in feed, mineral substance premix, add by 0.01%), all the other 1 group (the 2nd group) feed of feeding containing Chinese medicine composition (feed routinely by quail perfect compound feed, in feed, premix replaces with premix of the present invention), feed 20 days, other condition such as feeding and management method is all consistent, in whole process of the test, the each group of equal free choice feeding of young quail and drinking-water.
To carrying out the stimulation of quail cold stress: get above-mentioned two groups of equal healthy quails, often organize and get 100 respectively, carry out cold stress process respectively at 12 ± 1 DEG C, stress time 10d respectively.In whole process of the test, each group equal free choice feeding of young quail and drinking-water, search for food as the conventional daily ration of quail.The clinical manifestation of keeper's observed and recorded.In experimentation, choose the quail (being all considered as disease quail of the symptom of digestive tract such as all appearance are suffered from diarrhoea, have blood in stool, dysentery, lassitude) occurring intestinal inflammatory symptom count.
Results and analysis
Table 2 clinical test results
| Group | Morbidity number | Healthy number | The incidence of disease | Self-healing |
| 1st group | 40 | 60 | 40% | 6 |
| 2nd group | 5 | 95 | 5% | 4 |
Table 2 analysis result shows, illustrates that feed of the present invention all has obvious prevention effect to the quail all kinds intestinal inflammatory caused by cold stress.
Claims (5)
1. one kind is prevented the compound premix special of quail cold stress enteritis, it is characterized in that this compound premix is made up of following raw material, with parts by weight: glucosidase procyanidins 10-20 part, dandelion 5-8 part, bark of eucommia 5-8 part, purslane 5-8 part, cordate houttuynia 5-8 part, Radix Astragali 5-8 part, plantain seed 5-8 part, mother chrysanthemum 5-8 part, vitamin A 0.5-0.8 part, vitamin D
30.01-0.3 part, Cobastab
10.05-0.07 part, Cobastab
20.5-1 part, Cobastab
60.1-0.6 part, Cobastab
120.08-0.1 part, folic acid 0.06-0.18 part, biotin 0.02-0.25 part, nicotinic acid 0.8-1.2 part; Kelp Powder 5-8 part, sodium selenite 2-3 part.
2. premix as claimed in claim 1, is characterized in that, each raw material drying is pulverized rear mixing and be get final product.
3. the application of premix as claimed in claim 1 or 2: Meat-type quail, under the condition of 12 ± 1 DEG C, adds this premix by weight 0.003%-0.05% in Meat-type quail adequate diet.
4. a kind of preparation method preventing the compound premix of quail cold stress enteritis described in claim 1, dandelion 5-8 part, bark of eucommia 5-8 part, purslane 5-8 part, cordate houttuynia 5-8 part, Radix Astragali 5-8 part, plantain seed 5-8 part, mother chrysanthemum 5-8 part are mixed and made into the trickle powder of 600 object by this preparation method, with the warm water of 60 DEG C, by weight, 2 hours are soaked with the material-water ratio of 1:2, again with slow fire heating 30-50 minute, concentration is 1/2nd of original volume, filter to get filtrate, mix with other raw material of described weight portion and get final product after dusting.
5. the application of the premix of method acquisition as claimed in claim 4: Meat-type quail, under the condition of 12 ± 1 DEG C, adds this premix by weight 0.003%-0.05% in Meat-type quail adequate diet.
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| CN201410459881.3A CN104187168B (en) | 2014-09-11 | 2014-09-11 | A kind of compound premix preventing quail cold stress enteritis |
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| CN104187168B true CN104187168B (en) | 2016-04-06 |
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Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1126551A (en) * | 1995-07-11 | 1996-07-17 | 张映春 | Converting agent for multivitamin chicken feed |
| WO2004091307A2 (en) * | 2003-04-08 | 2004-10-28 | Advanced Bionutriton Corporation | Feed additives against diseasse infection in terrestrial and aquatic animals |
| CN100413857C (en) * | 2004-02-13 | 2008-08-27 | 杭州利欣生物科技有限公司 | Procyanidins oligomer and its preparing method and use |
| CN101485399B (en) * | 2009-02-25 | 2011-11-09 | 山东中基牧业发展有限公司 | Processing technique of composite premix feed for egg-laying quail |
| CN103271235B (en) * | 2013-04-02 | 2014-04-23 | 中国农业科学院北京畜牧兽医研究所 | Application of oligomeric procyanidine as feed additive for prolonging shelf lives of eggs |
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